TCONS_00034961-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00034961-protein
Unique NameTCONS_00034961-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length452

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00034961-protein ID=TCONS_00034961-protein|Name=TCONS_00034961-protein|organism=Clytia hemisphaerica|type=polypeptide|length=452bp
HKSIKKKKKGKMLAIIWLLTFHIDVSLAQQNVASPDSIVSQDEMTYLTEK
LFRNYNKKAIPIVNGQPIEVKVKLGILDMVPKEHAKLHFSMDSYIQYRWI
DPRLEFNFTKATKARFLAYDWRVLEDLWTPNLYFIEAKFGMQHEIPDPNL
LVFISPDGEVLLHRRLSITSFCPMKLEKFPFDVQHCSMTIEPYSYHTVYL
RLAWDRLTWLNLELQDFADVSIKMNSLPFYKYTPISEKSWSRLVVKFQFR
RNIDLYLFRDFLPCIFIVALSWINFWVNYRSTPARVLLSITTVLTIVTMT
NQIRLTSPSEELFRSIDYYMMFCNLFVFAALLETTMVGMTAPNSKPADRL
QQIMDILQNDDDDDDDETLHETHEQPTGDGNEGKQNDKKATINEFPLMET
FKLGPLHFYKGETHNVDKYSRILFPLSFMVFNIAFFVAHLFDNTVWSTSA
HA
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_020353XLOC_020353Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00034961TCONS_00034961Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR006201Neur_channel
IPR006028GABAA/Glycine_rcpt
IPR006029Neurotrans-gated_channel_TM
IPR006202Neur_chan_lig-bd
IPR018000Neurotransmitter_ion_chnl_CS
Vocabulary: Cellular Component
TermDefinition
GO:0016021integral component of membrane
Vocabulary: Biological Process
TermDefinition
GO:0006811ion transport
Vocabulary: Molecular Function
TermDefinition
GO:0005216ion channel activity
GO:0005230extracellular ligand-gated ion channel activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006811 ion transport
cellular_component GO:0016021 integral component of membrane
molecular_function GO:0005230 extracellular ligand-gated ion channel activity
molecular_function GO:0005216 ion channel activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR006201Neurotransmitter-gated ion-channelPRINTSPR00252NRIONCHANNELcoord: 126..137
score: 26.09
coord: 247..259
score: 26.35
coord: 90..106
score: 29.17
coord: 172..186
score: 52.04
IPR006028Gamma-aminobutyric acid A receptor/Glycine receptor alphaPRINTSPR00253GABAARECEPTRcoord: 282..303
score: 46.14
coord: 316..337
score: 45.09
coord: 419..439
score: 40.16
coord: 256..276
score: 39.99
IPR006029Neurotransmitter-gated ion-channel transmembrane domainPFAMPF02932Neur_chan_membcoord: 262..342
e-value: 8.2E-19
score: 68.5
IPR006029Neurotransmitter-gated ion-channel transmembrane domainSUPERFAMILY90112Neurotransmitter-gated ion-channel transmembrane porecoord: 256..441
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainPFAMPF02931Neur_chan_LBDcoord: 47..252
e-value: 2.9E-38
score: 131.4
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainGENE3D2.70.170.10coord: 39..257
e-value: 1.8E-42
score: 144.7
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainSUPERFAMILY63712Nicotinic receptor ligand binding domain-likecoord: 45..252
NoneNo IPR availableGENE3D1.20.58.390coord: 258..447
e-value: 9.3E-33
score: 112.8
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 361..387
IPR018000Neurotransmitter-gated ion-channel, conserved sitePROSITEPS00236NEUROTR_ION_CHANNELcoord: 172..186

Blast
BLAST of TCONS_00034961-protein vs. Swiss-Prot (Human)
Match: GBRB1 (Gamma-aminobutyric acid receptor subunit beta-1 OS=Homo sapiens GN=GABRB1 PE=1 SV=2)

HSP 1 Score: 191.815 bits (486), Expect = 1.008e-55
Identity = 133/478 (27.82%), Postives = 228/478 (47.70%), Query Frame = 0
Query:   16 IWLLTFHIDVSLAQQNVASPDSIVSQDEMTYLTE---KLFRNYNKKAIPIVNGQPIEVKVKLGI--LDMVPKEHAKLHFSMDSYIQYRWIDPRLEFNFTKATKARFLAYDWRVLEDLWTPNLYFIEAKFGMQHEIPDPNLLVFISPDGEVLLHRRLSITSFCPMKLEKFPFDVQHCSMTIEPYSYHTVYLRLAWD----RLTWLN-LELQDFADVSIKMNSLPFYKYTPISEKSWSRLVVKFQFRRNIDLYLFRDFLPCIFIVALSWINFWVNYRSTPARVLLSITTVLTIVTMTNQIRLTSPSEELFRSIDYYMMFCNLFVFAALLETTMVGM----TAPNSKPADRLQQI--------MDILQNDDDDDDDETLHETHEQPTGDGNEGKQNDKKATINEF---------PLMETFKLGPLHFYKG----------------------ETHNVDKYSRILFPLSFMVFNIAFFVAHL 440
            + LL+F + +++    V    S      M+Y+ E   +L + Y+ +  P   G P++V +++ +  +DMV      + +++  Y Q  W D RL ++         L  D RV + LW P+ YF+  K    H +   N ++ + PDG VL   R++ T+ C M L ++P D Q+C++ IE Y Y T  +   W+     +T +N +EL  F+ V  KM S    K    +  ++ RL + F+ +RNI  ++ + ++P   I  LSW++FW+NY ++ ARV L ITTVLT+ T++  +R T P     ++ID Y+M C +FVF ALLE   V        P  K A +  Q         M+ +Q D   +   +  E   + +G       +D KAT+  +         PL      G      G                      + +++DK+SR+ FP++F +FN+ +++ ++
Sbjct:   10 LGLLSFPVMITM----VCCAHSTNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPPVDVGMRIDVASIDMV--SEVNMDYTLTMYFQQSWKDKRLSYSGIPLN----LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWNGGEGAVTGVNKIELPQFSIVDYKMVS----KKVEFTTGAYPRLSLSFRLKRNIGYFILQTYMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTISTHLRETLPKIPYVKAIDIYLMGCFVFVFLALLEYAFVNYIFFGKGPQKKGASKQDQSANEKNKLEMNKVQVDAHGNILLSTLEIRNETSGSEVLTSVSDPKATMYSYDSASIQYRKPLSSREAYGRALDRHGVPSKGRIRRRASQLKVKIPDLTDVNSIDKWSRMFFPITFSLFNVVYWLYYV 473          
The following BLAST results are available for this feature:
BLAST of TCONS_00034961-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
GBRB11.008e-5527.82Gamma-aminobutyric acid receptor subunit beta-1 OS... [more]
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