TCONS_00017220-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00017220-protein
Unique NameTCONS_00017220-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length391

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00017220-protein ID=TCONS_00017220-protein|Name=TCONS_00017220-protein|organism=Clytia hemisphaerica|type=polypeptide|length=391bp
MKEKNFVVLLIVVSVASTTAAHKLHHHNHKKNFTTDFNGAPPPPGAGADL
GPDESVMDHIMKVNLRKADGHDAPHMYTDDGSYVELFEGDIIKTPRLEDE
VAEMKDGSQGGLRANDAINRGQWTDGEIPYTFHSYFSSAGRSVVRKAIEV
FKKHTCIKFRPRSGSDHNYVTFMHGGGCSSMIGMQGGRQQISLANGCLVT
GIAVHEMMHAAGFYHEQSRRDRDQYIRINWSNINRPMWYNFQKYQSGQAS
TLGEAYDKKSVMHYGNYAFSINGRKTIQSLSNYNEVLGQRSGFSKIDIAQ
LNKYYNCKNTGGGGGGGGGGGGGSGFKDNYEFCFLLPKYCKNSWVKTNCQ
KTCCVDKYKDMCPYWRQRGFCTASDNKNWMKLNCPKSCGFC
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_009637XLOC_009637Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00017220TCONS_00017220Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001506Peptidase_M12A
IPR003582ShKT_dom
IPR006026Peptidase_Metallo
IPR024079MetalloPept_cat_dom
IPR034035Astacin-like_dom
Vocabulary: Molecular Function
TermDefinition
GO:0004222metalloendopeptidase activity
GO:0008237metallopeptidase activity
GO:0008270zinc ion binding
Vocabulary: Biological Process
TermDefinition
GO:0006508proteolysis
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006508 proteolysis
molecular_function GO:0004222 metalloendopeptidase activity
molecular_function GO:0008237 metallopeptidase activity
molecular_function GO:0008270 zinc ion binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001506Peptidase M12APRINTSPR00480ASTACINcoord: 144..162
score: 35.44
coord: 216..233
score: 52.04
coord: 197..215
score: 51.23
coord: 293..306
score: 43.33
coord: 255..270
score: 51.35
IPR001506Peptidase M12APFAMPF01400Astacincoord: 122..308
e-value: 4.0E-67
score: 225.4
IPR003582ShKT domainSMARTSM00254ShkT_1coord: 306..353
e-value: 31.0
score: 4.6
coord: 354..391
e-value: 0.013
score: 24.6
IPR003582ShKT domainPFAMPF01549ShKcoord: 330..353
e-value: 1.3
score: 9.6
coord: 354..391
e-value: 3.5E-9
score: 36.9
IPR003582ShKT domainPROSITEPS51670SHKTcoord: 353..391
score: 12.594
IPR006026Peptidase, metallopeptidaseSMARTSM00235col_5coord: 119..258
e-value: 2.7E-45
score: 166.5
IPR024079Metallopeptidase, catalytic domainGENE3D3.40.390.10coord: 116..309
e-value: 1.6E-58
score: 197.5
IPR034035Astacin-like metallopeptidase domainCDDcd04280ZnMc_astacin_likecoord: 125..305
e-value: 3.7713E-87
score: 263.663
NoneNo IPR availableSUPERFAMILY55486Metalloproteases ("zincins"), catalytic domaincoord: 122..307

Blast
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BLAST of TCONS_00017220-protein vs. Swiss-Prot (Human)
Match: MEP1A (Meprin A subunit alpha OS=Homo sapiens GN=MEP1A PE=1 SV=2)

HSP 1 Score: 142.895 bits (359), Expect = 2.770e-37
Identity = 81/229 (35.37%), Postives = 118/229 (51.53%), Query Frame = 0 
Query:   84 VELFEGDIIKTPRLEDEVAEMKDGSQGGLRANDAINRGQWTDGEIPYTFHSYFSSAGRSVVRKAIEVFKKHTCIKFRPRSGSDHNYVTFMHGGGCSSMIGMQGGRQQISLANGCLVTGIAVHEMMHAAGFYHEQSRRDRDQYIRINWSNINRPMWYNFQKYQSGQASTLGEAYDKKSVMHYGNYAFSINGR-KTIQS-LSNYNEVLGQRSGFSKIDIAQLNKYYNCKNT 310
            ++LF+GDI            +   S+ GLR  +     +WT   IPY          +  +  A E+F+  +C+ F+P  G + +Y+ F    GC S +G Q   Q IS+  GC    I  HE++HA GFYHEQSR DRD Y+ I W  I     +NF  Y     + L   YD +S+MHY  ++F+ N    TI + +  +N ++GQR  FS ID+ +LN+ YNC  T
Sbjct:   52 LDLFQGDI------------LLQKSRNGLRDPNT----RWT-FPIPYILADNLGLNAKGAILYAFEMFRLKSCVDFKPYEG-ESSYIIFQQFDGCWSEVGDQHVGQNISIGQGCAYKAIIEHEILHALGFYHEQSRTDRDDYVNIWWDQILSGYQHNFDTYDDSLITDLNTPYDYESLMHYQPFSFNKNASVPTITAKIPEFNSIIGQRLDFSAIDLERLNRMYNCTTT 262
The following BLAST results are available for this feature:
BLAST of TCONS_00017220-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
MEP1A2.770e-3735.37Meprin A subunit alpha OS=Homo sapiens GN=MEP1A PE... [more]
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