TCONS_00017220-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00017220-protein
Unique Name	TCONS_00017220-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	391

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00017220-protein ID=TCONS_00017220-protein|Name=TCONS_00017220-protein|organism=Clytia hemisphaerica|type=polypeptide|length=391bp
MKEKNFVVLLIVVSVASTTAAHKLHHHNHKKNFTTDFNGAPPPPGAGADL
GPDESVMDHIMKVNLRKADGHDAPHMYTDDGSYVELFEGDIIKTPRLEDE
VAEMKDGSQGGLRANDAINRGQWTDGEIPYTFHSYFSSAGRSVVRKAIEV
FKKHTCIKFRPRSGSDHNYVTFMHGGGCSSMIGMQGGRQQISLANGCLVT
GIAVHEMMHAAGFYHEQSRRDRDQYIRINWSNINRPMWYNFQKYQSGQAS
TLGEAYDKKSVMHYGNYAFSINGRKTIQSLSNYNEVLGQRSGFSKIDIAQ
LNKYYNCKNTGGGGGGGGGGGGGSGFKDNYEFCFLLPKYCKNSWVKTNCQ
KTCCVDKYKDMCPYWRQRGFCTASDNKNWMKLNCPKSCGFC

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_009637	XLOC_009637	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00017220	TCONS_00017220	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR001506	Peptidase_M12A
IPR003582	ShKT_dom
IPR006026	Peptidase_Metallo
IPR024079	MetalloPept_cat_dom
IPR034035	Astacin-like_dom

Vocabulary: **Molecular Function**
Term	Definition
GO:0004222	metalloendopeptidase activity
GO:0008237	metallopeptidase activity
GO:0008270	zinc ion binding

Vocabulary: **Biological Process**
Term	Definition
GO:0006508	proteolysis

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0006508	proteolysis
molecular_function	GO:0004222	metalloendopeptidase activity
molecular_function	GO:0008237	metallopeptidase activity
molecular_function	GO:0008270	zinc ion binding

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR001506	Peptidase M12A	PRINTS	PR00480	ASTACIN	coord: 144..162 score: 35.44 coord: 216..233 score: 52.04 coord: 197..215 score: 51.23 coord: 293..306 score: 43.33 coord: 255..270 score: 51.35
IPR001506	Peptidase M12A	PFAM	PF01400	Astacin	coord: 122..308 e-value: 4.0E-67 score: 225.4
IPR003582	ShKT domain	SMART	SM00254	ShkT_1	coord: 306..353 e-value: 31.0 score: 4.6 coord: 354..391 e-value: 0.013 score: 24.6
IPR003582	ShKT domain	PFAM	PF01549	ShK	coord: 330..353 e-value: 1.3 score: 9.6 coord: 354..391 e-value: 3.5E-9 score: 36.9
IPR003582	ShKT domain	PROSITE	PS51670	SHKT	coord: 353..391 score: 12.594
IPR006026	Peptidase, metallopeptidase	SMART	SM00235	col_5	coord: 119..258 e-value: 2.7E-45 score: 166.5
IPR024079	Metallopeptidase, catalytic domain	GENE3D	3.40.390.10		coord: 116..309 e-value: 1.6E-58 score: 197.5
IPR034035	Astacin-like metallopeptidase domain	CDD	cd04280	ZnMc_astacin_like	coord: 125..305 e-value: 3.7713E-87 score: 263.663
None	No IPR available	SUPERFAMILY	55486	Metalloproteases ("zincins"), catalytic domain	coord: 122..307

Blast

[Close]

BLAST of TCONS_00017220-protein vs. Swiss-Prot (Human)
Match: MEP1A (Meprin A subunit alpha OS=Homo sapiens GN=MEP1A PE=1 SV=2)

HSP 1 Score: 142.895 bits (359), Expect = 2.770e-37
Identity = 81/229 (35.37%), Postives = 118/229 (51.53%), Query Frame = 0

Query:   84 VELFEGDIIKTPRLEDEVAEMKDGSQGGLRANDAINRGQWTDGEIPYTFHSYFSSAGRSVVRKAIEVFKKHTCIKFRPRSGSDHNYVTFMHGGGCSSMIGMQGGRQQISLANGCLVTGIAVHEMMHAAGFYHEQSRRDRDQYIRINWSNINRPMWYNFQKYQSGQASTLGEAYDKKSVMHYGNYAFSINGR-KTIQS-LSNYNEVLGQRSGFSKIDIAQLNKYYNCKNT 310
            ++LF+GDI            +   S+ GLR  +     +WT   IPY          +  +  A E+F+  +C+ F+P  G + +Y+ F    GC S +G Q   Q IS+  GC    I  HE++HA GFYHEQSR DRD Y+ I W  I     +NF  Y     + L   YD +S+MHY  ++F+ N    TI + +  +N ++GQR  FS ID+ +LN+ YNC  T
Sbjct:   52 LDLFQGDI------------LLQKSRNGLRDPNT----RWT-FPIPYILADNLGLNAKGAILYAFEMFRLKSCVDFKPYEG-ESSYIIFQQFDGCWSEVGDQHVGQNISIGQGCAYKAIIEHEILHALGFYHEQSRTDRDDYVNIWWDQILSGYQHNFDTYDDSLITDLNTPYDYESLMHYQPFSFNKNASVPTITAKIPEFNSIIGQRLDFSAIDLERLNRMYNCTTT 262

The following BLAST results are available for this feature:

BLAST of TCONS_00017220-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00017220-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
MEP1A	2.770e-37	35.37	Meprin A subunit alpha OS=Homo sapiens GN=MEP1A PE...	[more]

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TCONS_00017220-protein (polypeptide) - C. hemisphaerica