TCONS_00017174-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00017174-protein
Unique Name	TCONS_00017174-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	689

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00017174-protein ID=TCONS_00017174-protein|Name=TCONS_00017174-protein|organism=Clytia hemisphaerica|type=polypeptide|length=689bp
MVNLRTLSNILIVLYIVGIFSATNANSHTRLQKINTEAGRRDKVFKKGAT
QAGHDRRFELRKNKLKQLMNVTKDSEDLSEGVEDQDLQPDGNAEFNPMEG
INVAEPIGYDATGLNYRSIPTEDSEQRLIANNEIFNDENTFINNGNALPP
LEDETENENALTPSESESTETVSEDPVSNALTDSEEQAANALTQSVDQGV
NALQTPSGENGNVQQTEEENAGMEKTETAEENPGSKSIVSFGDVFNWLKG
LFSKKLKKKKKKVQLQVLADDGEGGEEVEDDEKSKEEREEEENLKAKLLK
VFQEEKLKEKLKIGNQKLYNDDAKKKLAAALDEKAKSDKERAEKEKQKLV
AKLQNTKQQDDKQQQAPKLPDKPLQDDSVYKDDAENIQALQIQQNLQVEK
GQLQEQENLRKLHAMAIAASKARQKLINQLMQNATRLSEKSRQNIELWLK
NITGMDIGATTDLNSKLTNMDLMTLNRDYFIHHPPNHVIFFNQHQPMSNP
TTYHVTKYNGGHLVHHYEHFYNQNPSHVSVNHYVSRTKPCLNGGLIVPLG
NGEIGCVCKNGFYGPYCEDFDYCSLKPCKNRGKCYPIDVAPRIQCTCLKQ
FYGKLCEKVNPCFEHVCKNGGTCTHNGEGKTECVCKPGYNGDRCQYIDSC
LPSPCKNGGVCHQTVVDRLLNSGNFTCECPIQFKGPLCQ

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_009608	XLOC_009608	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00017174	TCONS_00017174	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR000742	EGF-like_dom
IPR001881	EGF-like_Ca-bd_dom
IPR013032	EGF-like_CS

Vocabulary: **Molecular Function**
Term	Definition
GO:0005509	calcium ion binding

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
molecular_function	GO:0005509	calcium ion binding

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 389..409
None	No IPR available	COILS	Coil	Coil	coord: 320..359
None	No IPR available	GENE3D	2.10.25.10		coord: 527..569 e-value: 2.6E-5 score: 23.6 coord: 647..689 e-value: 3.6E-10 score: 39.2
None	No IPR available	GENE3D	2.10.25.10		coord: 608..646 e-value: 3.2E-9 score: 36.0
None	No IPR available	GENE3D	2.10.25.10		coord: 570..607 e-value: 1.2E-7 score: 31.1
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 201..236
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 139..180
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 334..378
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 72..91
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 271..293
None	No IPR available	CDD	cd00054	EGF_CA	coord: 609..645 e-value: 1.35011E-6 score: 44.935
None	No IPR available	CDD	cd00054	EGF_CA	coord: 647..689 e-value: 7.39109E-6 score: 43.009
None	No IPR available	SUPERFAMILY	57196	EGF/Laminin	coord: 608..646
None	No IPR available	SUPERFAMILY	57196	EGF/Laminin	coord: 647..689
None	No IPR available	SUPERFAMILY	57196	EGF/Laminin	coord: 569..608
IPR000742	EGF-like domain	SMART	SM00181	egf_5	coord: 611..645 e-value: 0.0021 score: 27.3 coord: 572..607 e-value: 2.2 score: 17.3 coord: 649..689 e-value: 5.8E-4 score: 29.2 coord: 539..568 e-value: 220.0 score: 0.6
IPR000742	EGF-like domain	PFAM	PF00008	EGF	coord: 650..686 e-value: 6.0E-5 score: 23.2
IPR000742	EGF-like domain	PROSITE	PS50026	EGF_3	coord: 569..607 score: 16.759
IPR000742	EGF-like domain	PROSITE	PS50026	EGF_3	coord: 646..689 score: 14.29
IPR000742	EGF-like domain	PROSITE	PS50026	EGF_3	coord: 531..568 score: 10.878
IPR000742	EGF-like domain	PROSITE	PS50026	EGF_3	coord: 608..645 score: 19.878
IPR001881	EGF-like calcium-binding domain	SMART	SM00179	egfca_6	coord: 647..689 e-value: 0.13 score: 8.8 coord: 608..645 e-value: 0.039 score: 13.1 coord: 569..607 e-value: 0.19 score: 7.6
IPR013032	EGF-like, conserved site	PROSITE	PS00022	EGF_1	coord: 595..606
IPR013032	EGF-like, conserved site	PROSITE	PS01186	EGF_2	coord: 633..644
IPR013032	EGF-like, conserved site	PROSITE	PS01186	EGF_2	coord: 556..567
IPR013032	EGF-like, conserved site	PROSITE	PS00022	EGF_1	coord: 556..567
IPR013032	EGF-like, conserved site	PROSITE	PS00022	EGF_1	coord: 633..644
IPR013032	EGF-like, conserved site	PROSITE	PS00022	EGF_1	coord: 677..688

Blast

[Close]

BLAST of TCONS_00017174-protein vs. Swiss-Prot (Human)
Match: NOTC3 (Neurogenic locus notch homolog protein 3 OS=Homo sapiens GN=NOTCH3 PE=1 SV=2)

HSP 1 Score: 112.079 bits (279), Expect = 3.045e-25
Identity = 57/155 (36.77%), Postives = 76/155 (49.03%), Query Frame = 0

Query:  539 PCLNGGLIVPLGNGEIGCVCKNGFYGPYCEDFDYCSLKPCKNRGKCYPIDVA--PRIQCTCLKQFYGKLCEKVNPCFEHVCKNGGTCTHNGEGKTECVCKPGYNGDRCQY-IDSC-LPSPCKNGGVCHQTVVDRLLNSGNFTCECPIQFKGPLCQ 689
            PC NGG    L + E  C+C  G+ G  C+  D C   PC  RG C    VA   R  C C + F G  C   +PC    C +G  C+   +G+  C C PGY G  C+  +D C +  PC++GG C  T        G+F C+CP  + GPLC+
Sbjct:   48 PCANGGRCTQLPSREAACLCPPGWVGERCQLEDPCHSGPCAGRGVCQSSVVAGTARFSCRCPRGFRGPDCSLPDPCLSSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTCLNT-------PGSFRCQCPAGYTGPLCE 195

HSP 2 Score: 99.7525 bits (247), Expect = 2.001e-21
Identity = 63/154 (40.91%), Postives = 70/154 (45.45%), Query Frame = 0

Query:  539 PCLNGGLIVPLGNGEIGCVCKNGFYGPYC-EDFDYCSLKPCKNRGKCYPIDVAPRIQCTCLKQFYGKLCEKVNP-CFEHVCKNGGTCTHNGEGKTECVCKPGYNGDRCQY-IDSCLPSPCKNGGVCHQTVVDRLLNSGNFTCECPIQFKGPLCQ 689
            PCLNGG     G G   C C  GF GP C  D D C   PC   G C   D      CTC   + G  CE+  P C    C NGGTC  +G     C+C+PGY G  CQ+  D CL  PC +GGVC             F C C   F GP CQ
Sbjct:  857 PCLNGGSCQD-GVGSFSCSCLPGFAGPRCARDVDECLSNPC-GPGTC--TDHVASFTCTCPPGYGGFHCEQDLPDCSPSSCFNGGTCV-DGVNSFSCLCRPGYTGAHCQHEADPCLSRPCLHGGVCSAA-------HPGFRCTCLESFTGPQCQ 998

HSP 3 Score: 96.6709 bits (239), Expect = 1.872e-20
Identity = 57/157 (36.31%), Postives = 80/157 (50.96%), Query Frame = 0

Query:  536 RTKPCLNGGLIVPLGNGEIGCVCKNGFYGPYCE-DFDYCSLKPCKNRGKCYPIDVAPRIQCTCLKQFYGKLCEK-VNPCFEHVCKNGGTCTHNGEGKTECVCKPGYNGDRCQ-YIDSCLPSPCKNGGVCHQTVVDRLLNSGNFTCECPIQFKGPLCQ 689
            ++ PC+NGG+     NG   C C +GF G  C+ D D C+  PC+N  KC  +D     +C C + F G LC++ V+ C    C +G  C  +G     C C PGY G RC+  +D C   PC++GG C   +VD+ L      C CP    G  C+
Sbjct:  474 QSSPCVNGGVCKDRVNG-FSCTCPSGFSGSTCQLDVDECASTPCRNGAKC--VDQPDGYECRCAEGFEGTLCDRNVDDCSPDPCHHG-RCV-DGIASFSCACAPGYTGTRCESQVDECRSQPCRHGGKCLD-LVDKYL------CRCPSGTTGVNCE 618

HSP 4 Score: 94.7449 bits (234), Expect = 8.346e-20
Identity = 54/144 (37.50%), Postives = 70/144 (48.61%), Query Frame = 0

Query:  551 NGEIGCVCKNGFYGPYC-EDFDYCSL--KPCKNRGKCYPIDVAPRIQCTCLKQFYGKLCEK-VNPCFEHVCKNGGTCTHNGEGKTECVCKPGYNGDRCQY-IDSCLPSPCKNGGVCHQTVVDRLLNSGNFTCECPIQFKGPLCQ 689
            NG   C C  GF G  C +D D CS+   PC++ G+C  ++      C C + + G  CE  VN C    C+N  TC  +  G+  C+C  G+ G  C+  ID C  SPC NGGVC   V         F+C CP  F G  CQ
Sbjct:  372 NGRAICTCPPGFTGGACDQDVDECSIGANPCEHLGRC--VNTQGSFLCQCGRGYTGPRCETDVNECLSGPCRNQATCL-DRIGQFTCICMAGFTGTYCEVDIDECQSSPCVNGGVCKDRV-------NGFSCTCPSGFSGSTCQ 505

HSP 5 Score: 93.2041 bits (230), Expect = 2.358e-19
Identity = 50/156 (32.05%), Postives = 73/156 (46.79%), Query Frame = 0

Query:  537 TKPCLNGGLIVPLGNGEIGCVCKNGFYGPYCE-DFDYCSL-KPCKNRGKCYPIDVAPRIQCTCLKQFYGKLCEK-VNPCFEHVCKNGGTCTHNGEGKTECVCKPGYNGDRCQY-IDSCLPSPCKNGGVCHQTVVDRLLNSGNFTCECPIQFKGPLC 688
            + PC +G       +G   C C  G+ G  C  D D C + +PC++ G C  ++     +C C   + G LCE    PC    C+NGGTC  +G+   +C C PG+ G  C+  +D C    C NGG C   V         + C+CP ++ G  C
Sbjct:  125 SSPCAHGARCSVGPDGRFLCSCPPGYQGRSCRSDVDECRVGEPCRHGGTC--LNTPGSFRCQCPAGYTGPLCENPAVPCAPSPCRNGGTCRQSGDLTYDCACLPGFEGQNCEVNVDDCPGHRCLNGGTCVDGV-------NTYNCQCPPEWTGQFC 271

HSP 6 Score: 87.4261 bits (215), Expect = 1.586e-17
Identity = 58/200 (29.00%), Postives = 79/200 (39.50%), Query Frame = 0

Query:  537 TKPCLNGGLIVPLGNGEIGCVCKNGFYGPYCEDF-DYCSLKPCKNRGKCYP--------------------------------------------IDVAPRIQCTCLKQFYGKLCEK-VNPCFEHVCKNGGTCTHNGEGKTECVCKPGYNGDRCQ-YIDSCLPSPCKNGGVCHQTVVDRLLNSGNFTCECPIQFKGPLCQ 689
            ++PCL+GG+      G   C C   F GP C+   D+CS +PC+N G+C                                              +D      C C +   G  CE+ V+PC    C++GGTC     G   C C PGYNGD C+  +D C   PC++GG C   V         + C CP    G LC+
Sbjct:  968 SRPCLHGGVCSAAHPG-FRCTCLESFTGPQCQTLVDWCSRQPCQNGGRCVQTGAYCLCPPGWSGRLCDIRSLPCREAAAQIGVRLEQLCQAGGQCVDEDSSHYCVCPEGRTGSHCEQEVDPCLAQPCQHGGTC-RGYMGGYMCECLPGYNGDNCEDDVDECASQPCQHGGSCIDLV-------ARYLCSCPPGTLGVLCE 1158

HSP 7 Score: 85.8853 bits (211), Expect = 3.963e-17
Identity = 51/156 (32.69%), Postives = 72/156 (46.15%), Query Frame = 0

Query:  538 KPCLNGGLIVPLGNGEIGCVCKNGFYGPYCEDF---DYCSLKPCKNRGKCYPIDVAPRIQCTCLKQFYGKLCEKVNPCFEHVCKNGGTCTHNGEGKTECVCKPGYNGDRCQY-IDSCL-PSPCKNGGVCHQTVVDRLLNSGNFTCECPIQFKGPLC 688
            +PC +G  I     G   CVC+ G+ GP C      D C  +PC+  G C    +     CTC     G+ CE ++PC  + C++GG C         C C  G+ G RCQ  +D C  P+PC   G+C          +G+F+C C   + GP C
Sbjct:  702 EPCSHG--ICYDAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMG--FHCTCPPGVQGRQCELLSPCTPNPCEHGGRCESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICTNL-------AGSFSCTCHGGYTGPSC 846

HSP 8 Score: 85.5001 bits (210), Expect = 5.439e-17
Identity = 52/158 (32.91%), Postives = 73/158 (46.20%), Query Frame = 0

Query:  537 TKPCLNGGLIVPLGNGEIGCVCKNGFYGPYCEDFDY-CSLKPCKNRGKCYPIDVAPRIQCTCLKQFYGKLCEKV---NPCFEHVCKNGGTCTHNGEGKTECVCKPGYNGDRCQYIDSCLPSPCKNGGVCHQTVVDRLLNSGNF-TCECPIQFKGPLCQ 689
            + PC  GG  V   NG   C+C  G   P C    + C+ +PC + G CY  D     +C C   + G  C +    + C    C+ GGTC+ +G G   C C PG  G +C+ +  C P+PC++GG C           G    C CP  ++GP CQ
Sbjct:  663 SSPCGEGGSCVDGENG-FRCLCPPGSLPPLCLPPSHPCAHEPCSH-GICY--DAPGGFRCVCEPGWSGPRCSQSLARDACESQPCRAGGTCSSDGMG-FHCTCPPGVQGRQCELLSPCTPNPCEHGGRCESA-------PGQLPVCSCPQGWQGPRCQ 808

HSP 9 Score: 83.5741 bits (205), Expect = 2.119e-16
Identity = 56/157 (35.67%), Postives = 73/157 (46.50%), Query Frame = 0

Query:  537 TKPCLNGGLIVPLGNGEIGCVCKNGFYGPYCEDFDYCSLKPCKNRGKCYPIDVAP--RIQCTCLKQFYGKLCEK-VNPCFEHV-CKNGGTCTHNGEGKTECVCKPGYNGDRC-QYIDSCLPSPCKNGGVCHQTVVDRLLNSGNFTCECPIQFKGPLC 688
            ++PC  GG     G G   C C  G  G  CE    C+  PC++ G+C   + AP     C+C + + G  C++ V+ C     C   G CT N  G   C C  GY G  C Q I+ C P+PC NGG C   V       G+F+C C   F GP C
Sbjct:  740 SQPCRAGGTCSSDGMG-FHCTCPPGVQGRQCELLSPCTPNPCEHGGRC---ESAPGQLPVCSCPQGWQGPRCQQDVDECAGPAPCGPHGICT-NLAGSFSCTCHGGYTGPSCDQDINDCDPNPCLNGGSCQDGV-------GSFSCSCLPGFAGPRC 884

The following BLAST results are available for this feature:

BLAST of TCONS_00017174-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00017174-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
NOTC3	3.045e-25	36.77	Neurogenic locus notch homolog protein 3 OS=Homo s...	[more]

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TCONS_00017174-protein (polypeptide) - C. hemisphaerica