TCONS_00015027-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00015027-protein
Unique Name	TCONS_00015027-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	606

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00015027-protein ID=TCONS_00015027-protein|Name=TCONS_00015027-protein|organism=Clytia hemisphaerica|type=polypeptide|length=606bp
MICSVFNKSCSVMTTGLMIFILVLTTLTYLTDCKPTTSNDFVNTTTTLWT
TEAVNTTHRPSTTIDTLSDFPEWVIDYLVRYGYMDEKRAYKINKTPFNAA
DKLSYKRSELEAGLREYQDFMTLPTTGRLDKRTMEALHKKRCGMPDKVRR
DDTTFKMSLTPTGQRKKRDLVLQKVDKNKKGSGFASSKTTRRFYWNINPK
PKYGGLLRPNIWLSLEYAFNRWASVTDAVFIRGDRLNWSDILIGFWTKDH
GDGNPFDGPGGTVGHADVSNRNVHLDEEENWGAKPEDIFLWLHPSKGTDF
IQAAIHEIGHVLGLSHDKDSDSVMFPTLQQFQPLSYYSLSTSDMNRIKSS
FGRCEPDVIDAMFVNKFLDGKTYIIKGPFIYQMDERKREVVQSWPRATTL
PFLAPTFVDEAFWHTDHFLYFFNKDGYYIYDSTNDPTVNRSPLFNLNKNG
YDVGFRGLKHHKYIDAAMVMDYKDDITGKTKPTSFLFQDEWVYKWDKVET
NWQRSIIPAEKVADGWPKLIRNVFPGLPGRIDTAFTWSYDGRTYFFVGRY
FYIWDPVKNIADGLYPTYQWQNVCEIYLCQVAPTPNVYNCESWDLTMDNC
HGYCHN

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_008412	XLOC_008412	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00015027	TCONS_00015027	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR021190	Pept_M10A
IPR006026	Peptidase_Metallo
IPR018487	Hemopexin-like_repeat
IPR024079	MetalloPept_cat_dom
IPR001818	Pept_M10_metallopeptidase
IPR002477	Peptidoglycan-bd-like
IPR000585	Hemopexin-like_dom

Vocabulary: **Molecular Function**
Term	Definition
GO:0008270	zinc ion binding
GO:0004222	metalloendopeptidase activity
GO:0008237	metallopeptidase activity

Vocabulary: **Biological Process**
Term	Definition
GO:0006508	proteolysis

Vocabulary: **Cellular Component**
Term	Definition
GO:0031012	extracellular matrix

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0006508	proteolysis
cellular_component	GO:0031012	extracellular matrix
molecular_function	GO:0004222	metalloendopeptidase activity
molecular_function	GO:0008237	metallopeptidase activity
molecular_function	GO:0008270	zinc ion binding

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR021190	Peptidase M10A	PRINTS	PR00138	MATRIXIN	coord: 137..150 score: 40.24 coord: 215..230 score: 35.44 coord: 239..267 score: 52.82 coord: 339..352 score: 32.67 coord: 303..328 score: 47.89
IPR006026	Peptidase, metallopeptidase	SMART	SM00235	col_5	coord: 181..353 e-value: 9.1E-8 score: 41.8
IPR018487	Hemopexin-like repeats	SMART	SM00120	HX_rpt_3	coord: 359..406 e-value: 1.6 score: 14.0 coord: 531..574 e-value: 2.0 score: 13.2 coord: 408..448 e-value: 6.3 score: 9.5 coord: 464..529 e-value: 28.0 score: 4.6
IPR018487	Hemopexin-like repeats	PROSITE	PS51642	HEMOPEXIN_2	coord: 356..403 score: 10.814
IPR018487	Hemopexin-like repeats	PROSITE	PS51642	HEMOPEXIN_2	coord: 461..527 score: 10.308
IPR018487	Hemopexin-like repeats	PROSITE	PS51642	HEMOPEXIN_2	coord: 528..576 score: 10.868
IPR024079	Metallopeptidase, catalytic domain	GENE3D	3.40.390.10		coord: 68..358 e-value: 4.9E-46 score: 156.6
IPR001818	Peptidase M10, metallopeptidase	PFAM	PF00413	Peptidase_M10	coord: 211..351 e-value: 9.2E-27 score: 93.7
None	No IPR available	PIRSF	PIRSF001191	MMP_stromelysin	coord: 77..358 e-value: 2.0E-48 score: 163.1 coord: 404..509 e-value: 0.0057 score: 13.1 coord: 454..575 e-value: 7.1E-8 score: 29.3 coord: 355..448 e-value: 2.3E-7 score: 27.7
None	No IPR available	SUPERFAMILY	55486	Metalloproteases ("zincins"), catalytic domain	coord: 204..351
IPR002477	Peptidoglycan binding-like	PFAM	PF01471	PG_binding_1	coord: 76..137 e-value: 2.2E-7 score: 30.9
IPR002477	Peptidoglycan binding-like	SUPERFAMILY	47090	PGBD-like	coord: 67..146
IPR000585	Hemopexin-like domain	GENE3D	2.110.10.10		coord: 452..573 e-value: 1.2E-12 score: 47.5
IPR000585	Hemopexin-like domain	SUPERFAMILY	50923	Hemopexin-like domain	coord: 353..573

Blast

[Close]

BLAST of TCONS_00015027-protein vs. Swiss-Prot (Human)
Match: MMP12 (Macrophage metalloelastase OS=Homo sapiens GN=MMP12 PE=1 SV=1)

HSP 1 Score: 117.857 bits (294), Expect = 3.035e-28
Identity = 127/501 (25.35%), Postives = 211/501 (42.12%), Query Frame = 0

Query:   83 YMDEKRAYKINKTPFNAADKLSYKRSELEAGLREYQDFMTLPTTGRLDKRTMEALHKKRCGMPDKVRRDDTTFKMSLTPTGQRKKRDLVLQKVDKNKKGSGFASSKTTRRFYWNINPKPKYGGLLRPNIWLSLEYAFNRWASVTDAVFIRGDRLNWSDILIGFWTKDHGDGNPFDGPGGTVGHADVSNRNV----HLDEEENWGAKPEDIFLWLHPSKGTDFIQAAIHEIGHVLGLSHDKDSDSVMFPTLQQFQPLSYYSLSTSDMNRIKSSFG-----------------RCEPDV-IDAMFVNKFLDGKTYIIKGPFIY-QMDERKREVV----QSWPRATTLPFLAPTFVDEAF-WHTDHFLYFFNKDGYYIYDSTNDPTVNRSPLFNLNKNGYDVGFRGLKHHKYIDAAMVMDYKDDITGKTKPTSFLFQDEWVYKWDKVETNWQRSIIPAEKVADGWPKLIRNVFPGLPGRIDTAFTWSYDGRTYFFVGRYFYIWD 555
            Y+++    +INK P     K+ Y  + ++  ++E Q F+ L  TG+LD  T+E +H  RCG+PD              P G   ++  +  +++                   N  P      + R ++  ++  AF  W++VT   F + +    +DIL+ F    HGD + FDG GG + HA      +    H DE+E           W   S GT+    A+HEIGH LGL H  D  +VMFPT  ++  ++ + LS  D+  I+S +G                  C+P++  DA+     +  K +  K  F + ++ ER +  V      WP   TL    P+ ++ A+     + ++ F  D Y++         N  P  N  K+ +  GF      K IDAA        +       ++ F D   +++D+            + +  G+PKLI   F G+  +ID  F +S +   YFF G   + +D
Sbjct:   36 YLEKFYGLEINKLP---VTKMKYSGNLMKEKIQEMQHFLGLKVTGQLDTSTLEMMHAPRCGVPD-------VHHFREMPGGPVWRKHYITYRIN-------------------NYTPD-----MNREDVDYAIRKAFQVWSNVTPLKFSKINT-GMADILVVFARGAHGDFHAFDGKGGILAHAFGPGSGIGGDAHFDEDE----------FWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTY-KYVDINTFRLSADDIRGIQSLYGDPKENQRLPNPDNSEPALCDPNLSFDAVTT---VGNKIFFFKDRFFWLKVSERPKTSVNLISSLWP---TL----PSGIEAAYEIEARNQVFLFKDDKYWLIS-------NLRPEPNYPKSIHSFGFPNFV--KKIDAA--------VFNPRFYRTYFFVDNQYWRYDERR----------QMMDPGYPKLITKNFQGIGPKIDAVF-YSKNKYYYFFQGSNQFEYD 452

The following BLAST results are available for this feature:

BLAST of TCONS_00015027-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00015027-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
MMP12	3.035e-28	25.35	Macrophage metalloelastase OS=Homo sapiens GN=MMP1...	[more]

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TCONS_00015027-protein (polypeptide) - C. hemisphaerica