TCONS_00015027-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00015027-protein
Unique NameTCONS_00015027-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length606

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00015027-protein ID=TCONS_00015027-protein|Name=TCONS_00015027-protein|organism=Clytia hemisphaerica|type=polypeptide|length=606bp
MICSVFNKSCSVMTTGLMIFILVLTTLTYLTDCKPTTSNDFVNTTTTLWT
TEAVNTTHRPSTTIDTLSDFPEWVIDYLVRYGYMDEKRAYKINKTPFNAA
DKLSYKRSELEAGLREYQDFMTLPTTGRLDKRTMEALHKKRCGMPDKVRR
DDTTFKMSLTPTGQRKKRDLVLQKVDKNKKGSGFASSKTTRRFYWNINPK
PKYGGLLRPNIWLSLEYAFNRWASVTDAVFIRGDRLNWSDILIGFWTKDH
GDGNPFDGPGGTVGHADVSNRNVHLDEEENWGAKPEDIFLWLHPSKGTDF
IQAAIHEIGHVLGLSHDKDSDSVMFPTLQQFQPLSYYSLSTSDMNRIKSS
FGRCEPDVIDAMFVNKFLDGKTYIIKGPFIYQMDERKREVVQSWPRATTL
PFLAPTFVDEAFWHTDHFLYFFNKDGYYIYDSTNDPTVNRSPLFNLNKNG
YDVGFRGLKHHKYIDAAMVMDYKDDITGKTKPTSFLFQDEWVYKWDKVET
NWQRSIIPAEKVADGWPKLIRNVFPGLPGRIDTAFTWSYDGRTYFFVGRY
FYIWDPVKNIADGLYPTYQWQNVCEIYLCQVAPTPNVYNCESWDLTMDNC
HGYCHN
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_008412XLOC_008412Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00015027TCONS_00015027Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR021190Pept_M10A
IPR006026Peptidase_Metallo
IPR018487Hemopexin-like_repeat
IPR024079MetalloPept_cat_dom
IPR001818Pept_M10_metallopeptidase
IPR002477Peptidoglycan-bd-like
IPR000585Hemopexin-like_dom
Vocabulary: Molecular Function
TermDefinition
GO:0008270zinc ion binding
GO:0004222metalloendopeptidase activity
GO:0008237metallopeptidase activity
Vocabulary: Biological Process
TermDefinition
GO:0006508proteolysis
Vocabulary: Cellular Component
TermDefinition
GO:0031012extracellular matrix
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006508 proteolysis
cellular_component GO:0031012 extracellular matrix
molecular_function GO:0004222 metalloendopeptidase activity
molecular_function GO:0008237 metallopeptidase activity
molecular_function GO:0008270 zinc ion binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR021190Peptidase M10APRINTSPR00138MATRIXINcoord: 137..150
score: 40.24
coord: 215..230
score: 35.44
coord: 239..267
score: 52.82
coord: 339..352
score: 32.67
coord: 303..328
score: 47.89
IPR006026Peptidase, metallopeptidaseSMARTSM00235col_5coord: 181..353
e-value: 9.1E-8
score: 41.8
IPR018487Hemopexin-like repeatsSMARTSM00120HX_rpt_3coord: 359..406
e-value: 1.6
score: 14.0
coord: 531..574
e-value: 2.0
score: 13.2
coord: 408..448
e-value: 6.3
score: 9.5
coord: 464..529
e-value: 28.0
score: 4.6
IPR018487Hemopexin-like repeatsPROSITEPS51642HEMOPEXIN_2coord: 356..403
score: 10.814
IPR018487Hemopexin-like repeatsPROSITEPS51642HEMOPEXIN_2coord: 461..527
score: 10.308
IPR018487Hemopexin-like repeatsPROSITEPS51642HEMOPEXIN_2coord: 528..576
score: 10.868
IPR024079Metallopeptidase, catalytic domainGENE3D3.40.390.10coord: 68..358
e-value: 4.9E-46
score: 156.6
IPR001818Peptidase M10, metallopeptidasePFAMPF00413Peptidase_M10coord: 211..351
e-value: 9.2E-27
score: 93.7
NoneNo IPR availablePIRSFPIRSF001191MMP_stromelysincoord: 77..358
e-value: 2.0E-48
score: 163.1
coord: 404..509
e-value: 0.0057
score: 13.1
coord: 454..575
e-value: 7.1E-8
score: 29.3
coord: 355..448
e-value: 2.3E-7
score: 27.7
NoneNo IPR availableSUPERFAMILY55486Metalloproteases ("zincins"), catalytic domaincoord: 204..351
IPR002477Peptidoglycan binding-likePFAMPF01471PG_binding_1coord: 76..137
e-value: 2.2E-7
score: 30.9
IPR002477Peptidoglycan binding-likeSUPERFAMILY47090PGBD-likecoord: 67..146
IPR000585Hemopexin-like domainGENE3D2.110.10.10coord: 452..573
e-value: 1.2E-12
score: 47.5
IPR000585Hemopexin-like domainSUPERFAMILY50923Hemopexin-like domaincoord: 353..573

Blast
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BLAST of TCONS_00015027-protein vs. Swiss-Prot (Human)
Match: MMP12 (Macrophage metalloelastase OS=Homo sapiens GN=MMP12 PE=1 SV=1)

HSP 1 Score: 117.857 bits (294), Expect = 3.035e-28
Identity = 127/501 (25.35%), Postives = 211/501 (42.12%), Query Frame = 0 
Query:   83 YMDEKRAYKINKTPFNAADKLSYKRSELEAGLREYQDFMTLPTTGRLDKRTMEALHKKRCGMPDKVRRDDTTFKMSLTPTGQRKKRDLVLQKVDKNKKGSGFASSKTTRRFYWNINPKPKYGGLLRPNIWLSLEYAFNRWASVTDAVFIRGDRLNWSDILIGFWTKDHGDGNPFDGPGGTVGHADVSNRNV----HLDEEENWGAKPEDIFLWLHPSKGTDFIQAAIHEIGHVLGLSHDKDSDSVMFPTLQQFQPLSYYSLSTSDMNRIKSSFG-----------------RCEPDV-IDAMFVNKFLDGKTYIIKGPFIY-QMDERKREVV----QSWPRATTLPFLAPTFVDEAF-WHTDHFLYFFNKDGYYIYDSTNDPTVNRSPLFNLNKNGYDVGFRGLKHHKYIDAAMVMDYKDDITGKTKPTSFLFQDEWVYKWDKVETNWQRSIIPAEKVADGWPKLIRNVFPGLPGRIDTAFTWSYDGRTYFFVGRYFYIWD 555
            Y+++    +INK P     K+ Y  + ++  ++E Q F+ L  TG+LD  T+E +H  RCG+PD              P G   ++  +  +++                   N  P      + R ++  ++  AF  W++VT   F + +    +DIL+ F    HGD + FDG GG + HA      +    H DE+E           W   S GT+    A+HEIGH LGL H  D  +VMFPT  ++  ++ + LS  D+  I+S +G                  C+P++  DA+     +  K +  K  F + ++ ER +  V      WP   TL    P+ ++ A+     + ++ F  D Y++         N  P  N  K+ +  GF      K IDAA        +       ++ F D   +++D+            + +  G+PKLI   F G+  +ID  F +S +   YFF G   + +D
Sbjct:   36 YLEKFYGLEINKLP---VTKMKYSGNLMKEKIQEMQHFLGLKVTGQLDTSTLEMMHAPRCGVPD-------VHHFREMPGGPVWRKHYITYRIN-------------------NYTPD-----MNREDVDYAIRKAFQVWSNVTPLKFSKINT-GMADILVVFARGAHGDFHAFDGKGGILAHAFGPGSGIGGDAHFDEDE----------FWTTHSGGTNLFLTAVHEIGHSLGLGHSSDPKAVMFPTY-KYVDINTFRLSADDIRGIQSLYGDPKENQRLPNPDNSEPALCDPNLSFDAVTT---VGNKIFFFKDRFFWLKVSERPKTSVNLISSLWP---TL----PSGIEAAYEIEARNQVFLFKDDKYWLIS-------NLRPEPNYPKSIHSFGFPNFV--KKIDAA--------VFNPRFYRTYFFVDNQYWRYDERR----------QMMDPGYPKLITKNFQGIGPKIDAVF-YSKNKYYYFFQGSNQFEYD 452
The following BLAST results are available for this feature:
BLAST of TCONS_00015027-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
MMP123.035e-2825.35Macrophage metalloelastase OS=Homo sapiens GN=MMP1... [more]
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