Secreted tripeptidyl peptidase (polypeptide) - C. hemisphaerica

Overview


Name	Secreted tripeptidyl peptidase
Unique Name	TCONS_00025980-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	562

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00025980-protein ID=TCONS_00025980-protein|Name=Secreted tripeptidyl peptidase|organism=Clytia hemisphaerica|type=polypeptide|length=562bp
MKGLGLLLLICCCTPLEAVVYSSLEADQSIDYWQDEGWERLERVESHKII
ELSFALKQENLQQFEELFWKVSDPDSPFYGKYLSADEITDMIAPSYETIT
LIEKWLANHGVFDCDLVANRDYMNCRMSCKTAEEILTGAVFFYFRHDKYH
KKVIRSASRYYIHAYIAEYLDFVGGVHRFPAVNWLKTKIEDMPEVNAHNR
GVHVGVYPKILRQRYNLTTDDIGSHPNNSQVVAQFLEQYFSNADLGEFMS
MFVKNDFTHQSEINKVIGPNGAKSGIEASLDTQYIMGTGANITTWFWSTA
GRHDNQEPFLLWLQNVASTKEVPPVHSVSYGDVESSLSVPYMQRVNTEFM
KAGVRGITILFASGDDGAACKKGKFSPQFPVSSPYITGVGGTGFSNPFTV
GPEFAYEISGGGFSNVFDQPKYQTDAVAAYMHTEGVPPQNLFNKTGRAYP
DIAALCRHFWVVNNRVPVPGVMGTSASTPSVAGIISMVNEHRLNANKPVM
GFLNPFIYKNPQAFYDVTSGCNEGCLTHDKGFCATEGFDPVTGYGSPNFP
DLVKAAMAVFKH

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_014617	XLOC_014617	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00025980	TCONS_00025980	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR015366	S53_propep
IPR000209	Peptidase_S8/S53_dom
IPR030400	Sedolisin_dom
IPR009020	Peptidase/Inhibitor_I9

Vocabulary: **Molecular Function**
Term	Definition
GO:0008236	serine-type peptidase activity
GO:0004252	serine-type endopeptidase activity

Vocabulary: **Biological Process**
Term	Definition
GO:0006508	proteolysis

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0006508	proteolysis
molecular_function	GO:0004252	serine-type endopeptidase activity
molecular_function	GO:0008236	serine-type peptidase activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR015366	Peptidase S53, activation domain	SMART	SM00944	Pro_kuma_activ_2	coord: 35..179 e-value: 2.3E-32 score: 123.5
IPR015366	Peptidase S53, activation domain	PFAM	PF09286	Pro-kuma_activ	coord: 37..179 e-value: 4.7E-28 score: 98.2
IPR015366	Peptidase S53, activation domain	CDD	cd11377	Pro-peptidase_S53	coord: 37..176 e-value: 8.72417E-37 score: 132.37
IPR000209	Peptidase S8/S53 domain	GENE3D	3.40.50.200		coord: 204..559 e-value: 7.3E-33 score: 113.4
IPR000209	Peptidase S8/S53 domain	SUPERFAMILY	52743	Subtilisin-like	coord: 205..557
IPR030400	Sedolisin domain	PROSITE	PS51695	SEDOLISIN	coord: 205..559 score: 31.502
IPR030400	Sedolisin domain	CDD	cd04056	Peptidases_S53	coord: 205..553 e-value: 2.81766E-118 score: 356.241
IPR009020	Protease propeptides/proteinase inhibitor I9	SUPERFAMILY	54897	Protease propeptides/inhibitors	coord: 36..185

Blast

[Close]

BLAST of Secreted tripeptidyl peptidase vs. Swiss-Prot (Human)
Match: TPP1 (Tripeptidyl-peptidase 1 OS=Homo sapiens GN=TPP1 PE=1 SV=2)

HSP 1 Score: 518.85 bits (1335), Expect = 7.304e-180
Identity = 268/565 (47.43%), Postives = 367/565 (64.96%), Query Frame = 0

Query:    4 LGLLLLICCCTPLEAVVYSSLEADQSIDYWQDEGWERLERVESHKIIELSFALKQENLQQFEELFWKVSDPDSPFYGKYLSADEITDMIAPSYETITLIEKWLANHGVFDCDLVANRDYMNCRMSCKTAEEILTGAVFFYFRHDKYHKKVIRSASRYYIHAYIAEYLDFVGGVHRFPAVNWLKTKIEDMPEVNAHNRGVHVGVYPKILRQRYNLTTDDIGS-HPNNSQVVAQFLEQYFSNADLGEFMSMFVKNDFTHQSEINKVIGPNG-AKSGIEASLDTQYIMGTGANITTWFWSTAGRHDNQEPFLLWLQNVASTKEVPPVHSVSYGDVESSLSVPYMQRVNTEFMKAGVRGITILFASGDDGAAC----KKGKFSPQFPVSSPYITGVGGTGFSNPFTVGPEFAYEISGGGFSNVFDQPKYQTDAVAAYMHTEGVPPQNL-FNKTGRAYPDIAALCRHFWVVNNRVPVPGVMGTSASTPSVAGIISMVNEHRLNANKPVMGFLNPFIYKNPQA-FYDVTSGCNEGCLTHD---KGFCATEGFDPVTGYGSPNFPDLVKAAM 557
            LGL  LI     L      S E DQ        GW  L R +  + + L+FAL+Q+N+++  EL   VSDP SP YGKYL+ + + D++ PS  T+  ++KWL   G   C  V  +D++ C +S + AE +L GA F ++        V+RS   Y +   +A ++DFVGG+HRFP  + L+ + E  P+V     G+H+GV P ++R+RYNLT+ D+GS   NNSQ  AQFLEQYF ++DL +FM +F  N F HQ+ + +V+G  G  ++GIEASLD QY+M  GANI+TW +S+ GRH+ QEPFL WL  +++   +P VH+VSYGD E SLS  Y+QRVNTE MKA  RG+T+LFASGD GA C     + +F P FP SSPY+T VGGT F  PF +  E    ISGGGFSNVF +P YQ +AV  ++ +    P +  FN +GRAYPD+AAL   +WVV+NRVP+P V GTSASTP   GI+S++NEHR+ + +P +GFLNP +Y+   A  +DVT GC+E CL  +   +GFC+  G+DPVTG+G+PNFP L+K  +
Sbjct:    8 LGLFALI-----LSGKCSYSPEPDQRRTL--PPGWVSLGRADPEEELSLTFALRQQNVERLSELVQAVSDPSSPQYGKYLTLENVADLVRPSPLTLHTVQKWLLAAGAQKCHSVITQDFLTCWLSIRQAELLLPGAEFHHYVGGPTETHVVRSPHPYQLPQALAPHVDFVGGLHRFPPTSSLRQRPE--PQVTG-TVGLHLGVTPSVIRKRYNLTSQDVGSGTSNNSQACAQFLEQYFHDSDLAQFMRLFGGN-FAHQASVARVVGQQGRGRAGIEASLDVQYLMSAGANISTWVYSSPGRHEGQEPFLQWLMLLSNESALPHVHTVSYGDDEDSLSSAYIQRVNTELMKAAARGLTLLFASGDSGAGCWSVSGRHQFRPTFPASSPYVTTVGGTSFQEPFLITNEIVDYISGGGFSNVFPRPSYQEEAVTKFLSSSPHLPPSSYFNASGRAYPDVAALSDGYWVVSNRVPIPWVSGTSASTPVFGGILSLINEHRILSGRPPLGFLNPRLYQQHGAGLFDVTRGCHESCLDEEVEGQGFCSGPGWDPVTGWGTPNFPALLKTLL 561

The following BLAST results are available for this feature:

BLAST of Secreted tripeptidyl peptidase vs. Swiss-Prot (Human)

BLAST of Secreted tripeptidyl peptidase vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
TPP1	7.304e-180	47.43	Tripeptidyl-peptidase 1 OS=Homo sapiens GN=TPP1 PE...	[more]

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Secreted tripeptidyl peptidase (polypeptide) - C. hemisphaerica