Asparaginase protein (polypeptide) - C. hemisphaerica

Overview
NameAsparaginase protein
Unique NameTCONS_00056024-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length654

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00056024-protein ID=TCONS_00056024-protein|Name=Asparaginase protein|organism=Clytia hemisphaerica|type=polypeptide|length=654bp
MLHSTQSGKVYENPLSGRKVARVLVIYTGGTIGMKDNGTGGYTVVPNYFA
QALKRLPMLYDEDFAESGMPELSNECEMNPDLPYCKYSKLVMPMSKMGVR
VVYYIKELDPILDSSNMSMEHWTMIAKVVKENYDYFDSFVILHGTDTMAY
TASALSYMFENLDKTVVLTGSQIPIFEQRNDGRSNFIGALVIAGHFIIPE
VTLFFNNKLFRGNRSQKVSASDLDAFDSPNLPPLAKLGTDIEVAWDAVFP
KTSMLPFHLHDKMSENVGLLQLFPGINAQIVRAFLSAPMEGIVIESFGSG
NIPSNRPDLVKEFKEAAERGVLMLNITQCARGTVTDAYAAGRVLFEIGVI
PGYDMTPEAALAKMAYVLSKKEITHSQRREFLEKNIRGEMTFPKTHKQFS
MKDGGLIQTVAKTLSLGSQQEMNSVRKTLLPVLLTCAAKAGDLNSIKDLV
DQGANLNEPSDYDGKTSLHLAAAEGHVNVVQYLLLHGASYFVRDRRGRTP
LFDAIRNKNSRIVDMLISSGANFDQDNMEVARELSIAATDNDVERLRLWL
RCNVNMNISDLEGRSPLHVAVLKGNKEAVKFLVEEAHVNVNRKDIFGRTP
IENAVELQSKDVLQILLQVLQNKRSNGTMNKLNGVTGDVNMNNLINCKMN
CGGN
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_035250XLOC_035250Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00056024TCONS_00056024Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR006034Asparaginase/glutaminase-like
IPR002110Ankyrin_rpt
IPR006033AsnASEI
IPR020683Ankyrin_rpt-contain_dom
IPR027474L-asparaginase_N
IPR027473L-asparaginase_C
IPR020827Asparaginase/glutaminase_AS1
Vocabulary: Molecular Function
TermDefinition
GO:0005515protein binding
GO:0004067asparaginase activity
Vocabulary: Biological Process
TermDefinition
GO:0006520cellular amino acid metabolic process
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006520 cellular amino acid metabolic process
molecular_function GO:0004067 asparaginase activity
molecular_function GO:0005515 protein binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR006034Asparaginase/glutaminase-likePRINTSPR00139ASNGLNASEcoord: 23..34
score: 49.21
coord: 316..334
score: 26.82
coord: 137..155
score: 59.4
IPR006034Asparaginase/glutaminase-likeSMARTSM00870Asparaginase_2coord: 22..378
e-value: 2.8E-113
score: 392.3
IPR006034Asparaginase/glutaminase-likePROSITEPS51732ASN_GLN_ASE_3coord: 21..385
score: 64.957
IPR006034Asparaginase/glutaminase-likeSUPERFAMILY53774Glutaminase/Asparaginasecoord: 101..395
coord: 18..61
IPR002110Ankyrin repeatPRINTSPR01415ANKYRINcoord: 512..526
score: 32.65
coord: 464..479
score: 42.83
IPR002110Ankyrin repeatSMARTSM00248ANK_2acoord: 596..625
e-value: 450.0
score: 7.6
coord: 463..492
e-value: 6.0E-5
score: 32.4
coord: 429..458
e-value: 160.0
score: 10.9
coord: 496..525
e-value: 0.0011
score: 28.2
coord: 562..592
e-value: 6.4E-4
score: 29.0
IPR002110Ankyrin repeatPROSITEPS50088ANK_REPEATcoord: 562..584
score: 10.606
IPR002110Ankyrin repeatPROSITEPS50088ANK_REPEATcoord: 496..528
score: 11.114
IPR002110Ankyrin repeatPROSITEPS50088ANK_REPEATcoord: 463..495
score: 14.212
IPR006033L-asparaginase, type ITIGRFAMTIGR00519TIGR00519coord: 107..391
e-value: 7.8E-82
score: 272.9
IPR020683Ankyrin repeat-containing domainGENE3D1.25.40.20coord: 516..629
e-value: 1.3E-22
score: 79.8
IPR020683Ankyrin repeat-containing domainPFAMPF12796Ank_2coord: 436..525
e-value: 1.1E-16
score: 61.1
coord: 534..618
e-value: 3.3E-11
score: 43.5
IPR020683Ankyrin repeat-containing domainGENE3D1.25.40.20coord: 403..515
e-value: 2.8E-26
score: 91.8
IPR020683Ankyrin repeat-containing domainPROSITEPS50297ANK_REP_REGIONcoord: 434..618
score: 45.997
IPR020683Ankyrin repeat-containing domainSUPERFAMILY48403Ankyrin repeatcoord: 433..618
IPR027474L-asparaginase, N-terminalPFAMPF00710Asparaginasecoord: 22..247
e-value: 3.3E-62
score: 209.4
IPR027474L-asparaginase, N-terminalGENE3D3.40.50.1170coord: 17..265
e-value: 3.5E-82
score: 274.1
IPR027473L-asparaginase, C-terminal domainGENE3D3.40.50.40coord: 266..393
e-value: 1.3E-37
score: 128.1
NoneNo IPR availablePIRSFPIRSF000654ILKcoord: 523..639
e-value: 2.3E-13
score: 47.5
coord: 364..531
e-value: 5.5E-20
score: 69.3
NoneNo IPR availableSFLDSFLDS00057Glutaminase/Asparaginasecoord: 18..394
e-value: 0.0
score: 431.9
NoneNo IPR availableCDDcd08963L-asparaginase_Icoord: 22..370
e-value: 1.94728E-113
score: 344.948
NoneNo IPR availableCDDcd00204ANKcoord: 461..583
e-value: 3.87927E-31
score: 117.485
NoneNo IPR availableCDDcd00204ANKcoord: 557..618
e-value: 3.11019E-11
score: 60.0898
IPR020827Asparaginase/glutaminase, active site 1PROSITEPS00144ASN_GLN_ASE_1coord: 25..33

Blast
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BLAST of Asparaginase protein vs. Swiss-Prot (Human)
Match: LPP60 (60 kDa lysophospholipase OS=Homo sapiens GN=ASPG PE=2 SV=3)

HSP 1 Score: 433.335 bits (1113), Expect = 5.950e-145
Identity = 236/564 (41.84%), Postives = 344/564 (60.99%), Query Frame = 0 
Query:   22 RVLVIYTGGTIGMKDNGTGGYTVVPNYFAQALKRLPMLYDEDFAES-GMPELSNECEMNPDLPYCKYSKLVMPMSKMGVRVVYYIKELDPILDSSNMSMEHWTMIAKVVKENYDYFDSFVILHGTDTMAYTASALSYMFENLDKTVVLTGSQIPIFEQRNDGRSNFIGALVIAGHFIIPEVTLFFNNKLFRGNRSQKVSASDLDAFDSPNLPPLAKLGTDIEVAWDAVFPKTSMLPFHLHDKMSENVGLLQLFPGINAQIVRAFLSAPMEGIVIESFGSGNIPSNRPDLVKEFKEAAERGVLMLNITQCARGTVTDAYAAGRVLFEIGVIPGYDMTPEAALAKMAYVLSKKEITHSQRREFLEKNIRGEMTFPKT-HKQFSMKDGGLIQTVAKTLSLGSQQEMNSVRKTLLPVLLTCAAKAGDLNSIKDLVDQGANLNEPSDYDGKTSLHLAAAEGHVNVVQYLLLHGASYFVRDRRGRTPLFDAIRNKNSRIVDMLISSGANFDQDNMEVA-RELSIAATDNDVERLRLWLRCNVNMNISDLEGRSPLHVAVLKGNKEAVKFL 582
            R+L +YTGGTIGM+     G  V     A  L+ LPM +DE+ A + G+ E                  LV+P +    R++Y + E  P+ DSS+M++  W  +A+ +K +Y+ +  FV++HGTDTMA+ AS LS+M ENL KTV+LTG+Q+PI    +DGR N +GAL++AG ++IPEV LFF N+LFRGNR+ KV A    AF SPNL PLA +G DI +  + V          +H  M ++VGLL+L+PGI A +VRAFL  P++G+V+E+FGSGN P+ +PDL++E + A ERG++++N T C +G VT  YAAG  +   GVI G+DMT EAALAK++YVL +  ++   R+E L K++RGEMT P    ++ S++   L   V+  LSL   QE +++R  L+P L   AA AGD+ +++ LV+ G++L    D++G+T LH AA  GH   V  LL  G     RD  G +PL  A+R ++  ++ +L  +GA+     +E A  EL   A   D+E L++W +   ++     +G S LHVA   GN   V FL
Sbjct:   10 RLLAVYTGGTIGMRSEL--GVLVPGTGLAAILRTLPMFHDEEHARARGLSE----------------DTLVLPPASRNQRILYTVLECQPLFDSSDMTIAEWVCLAQTIKRHYEQYHGFVVIHGTDTMAFAASMLSFMLENLQKTVILTGAQVPIHALWSDGRENLLGALLMAGQYVIPEVCLFFQNQLFRGNRATKVDARRFAAFCSPNLLPLATVGADITINRELVRKVDGKAGLVVHSSMEQDVGLLRLYPGIPAALVRAFLQPPLKGVVMETFGSGNGPT-KPDLLQELRVATERGLVIVNCTHCLQGAVTTDYAAGMAMAGAGVISGFDMTSEAALAKLSYVLGQPGLSLDVRKELLTKDLRGEMTPPSVEERRPSLQGNTLGGGVSWLLSLSGSQEADALRNALVPSLACAAAHAGDVEALQALVELGSDLGL-VDFNGQTPLHAAARGGHTEAVTMLLQRGVDVNTRDTDGFSPLLLAVRGRHPGVIGLLREAGASLSTQELEEAGTELCRLAYRADLEGLQVWWQAGADLGQPGYDGHSALHVAEAAGNLAVVAFL 553
The following BLAST results are available for this feature:
BLAST of Asparaginase protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
LPP605.950e-14541.8460 kDa lysophospholipase OS=Homo sapiens GN=ASPG P... [more]
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