TCONS_00053160-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00053160-protein
Unique NameTCONS_00053160-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length649

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00053160-protein ID=TCONS_00053160-protein|Name=TCONS_00053160-protein|organism=Clytia hemisphaerica|type=polypeptide|length=649bp
KKTKSTYRRMTPRFVKIHVTADDSFMKKHADKESAVKYINSLIKGTNLVF
RDKSLDASFHVILEGINYVKNREVKIQSKDPKKSLKDACRIMYDKKKELG
LDFHFGLFLTRRNFGYSGFTPLYRMCVNYKSCALAFDSGIRTSFIIAHEI
GHSVGIAHDGDHNECGVDVAHGSVMAPQVHSRFDRFFWSNCSRRQIHQNI
RYFSCLLKEKPPKINTSALDLPGVTHNLDGQCKYTFGRKYSGCLGIRSPD
QYCRFLFCRVPNQKNRCSYLSLPPVDGTICAKNQWCVKGKCIPFGRLTPT
PVDGGFSKWSAWSSCTTRCGPGVSKRYRKCDSPRPIFGGKPCNGSKTEWK
MCEDYTPCHIHKTFEDQRDDSCYAFGTGWKWFRPSDISRRLRNLSFDLNF
ENGFGSWTHAPNTTTKWQLHQGATQTPETGPSVDHTFGNKTGKYMYFESS
YPRLKGDNAMLVSPTILTPASCVRMYFHMLGKRIGTLKILQLDVNNTVIS
VLWKRSSSAGKYWYNIQFDVFYHKEYKIGIEATRGSSYLSDFAIDDIEIT
PGQCLDRRAEPTLDDTSPCRLYCRHPQKNYLQIGKDVSDGLKCSSTSSNI
CVDGKCQRLGCDGLIGSDKQYDKCGICGGKNIDYNCVHQEFNMQVQLTK
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_033553XLOC_033553Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00053160TCONS_00053160Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR006586ADAM_Cys-rich
IPR000884TSP1_rpt
IPR000998MAM_dom
IPR001590Peptidase_M12B
IPR024079MetalloPept_cat_dom
IPR013320ConA-like_dom
Vocabulary: Cellular Component
TermDefinition
GO:0016020membrane
Vocabulary: Molecular Function
TermDefinition
GO:0004222metalloendopeptidase activity
GO:0008237metallopeptidase activity
Vocabulary: Biological Process
TermDefinition
GO:0006508proteolysis
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006508 proteolysis
cellular_component GO:0016020 membrane
molecular_function GO:0004222 metalloendopeptidase activity
molecular_function GO:0008237 metallopeptidase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR006586ADAM, cysteine-richSMARTSM00608acrcoord: 214..294
e-value: 0.0044
score: -15.8
IPR000884Thrombospondin type-1 (TSP1) repeatSMARTSM00209TSP1_2coord: 306..359
e-value: 6.6E-8
score: 42.3
IPR000884Thrombospondin type-1 (TSP1) repeatPFAMPF00090TSP_1coord: 307..358
e-value: 4.6E-10
score: 39.5
IPR000884Thrombospondin type-1 (TSP1) repeatGENE3D2.20.100.10coord: 302..358
e-value: 8.7E-13
score: 47.9
IPR000884Thrombospondin type-1 (TSP1) repeatPROSITEPS50092TSP1coord: 303..359
score: 11.161
IPR000884Thrombospondin type-1 (TSP1) repeatSUPERFAMILY82895TSP-1 type 1 repeatcoord: 302..352
IPR000998MAM domainSMARTSM00137MAM_2coord: 393..556
e-value: 2.7E-25
score: 100.0
IPR000998MAM domainPFAMPF00629MAMcoord: 399..554
e-value: 6.8E-34
score: 117.0
IPR000998MAM domainPROSITEPS50060MAM_2coord: 396..556
score: 25.858
IPR000998MAM domainCDDcd06263MAMcoord: 399..554
e-value: 1.56719E-39
score: 141.361
IPR001590Peptidase M12B, ADAM/reprolysinPFAMPF01421Reprolysincoord: 13..202
e-value: 1.8E-15
score: 57.3
IPR001590Peptidase M12B, ADAM/reprolysinPROSITEPS50215ADAM_MEPROcoord: 13..200
score: 13.586
NoneNo IPR availableGENE3D2.60.120.200coord: 392..554
e-value: 5.4E-43
score: 146.4
NoneNo IPR availableSUPERFAMILY55486Metalloproteases ("zincins"), catalytic domaincoord: 10..208
IPR024079Metallopeptidase, catalytic domainGENE3D3.40.390.10coord: 9..230
e-value: 4.4E-44
score: 150.3
IPR013320Concanavalin A-like lectin/glucanase domainSUPERFAMILY49899Concanavalin A-like lectins/glucanasescoord: 395..554

Blast
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BLAST of TCONS_00053160-protein vs. Swiss-Prot (Human)
Match: ATS3 (A disintegrin and metalloproteinase with thrombospondin motifs 3 OS=Homo sapiens GN=ADAMTS3 PE=2 SV=4)

HSP 1 Score: 225.328 bits (573), Expect = 1.311e-62
Identity = 126/367 (34.33%), Postives = 201/367 (54.77%), Query Frame = 0 
Query:   15 VKIHVTADDSFMKKHADKESAVKYINSLIKGTNLVFRDKSLDASFHVILEG---INYVKNREVKIQSKDPKKSLKDACRIMYDKKK-ELGLDFHF--GLFLTRRNFG---YSGFTPLYRMCVNYKSCALAFDSGIRTSFIIAHEIGHSVGIAHDGDHNECGVDVAHGSVMAPQVHSRFDRFFWSNCSRRQIHQNIRYFSCLLKEKPPKINTSALDLPGVTHNLDGQCKYTFGRKYSGCLGIRSPDQYCRFLFCRVPNQKNRCSYLSLPPVDGTICAKNQWCVKGKCIPFGRLTPTPVDGGFSKWSAWSSCTTRCGPGVSKRYRKCDSPRPIFGGKPCNGSKTEWKMCEDYTPCHIHKTFEDQRDDSC 372
            +++ +  DDS ++ H  KE    Y+ +L+   N ++ D+SL    +V+L     + Y K+  + I+  +P +SL++ CR    +++ +L    H    +FLTR++FG     G+ P+  MC   +SC L  + G  ++F++AHE GH +G+ HDG  N CG + A GSVMAP V + F R+ WS CS +++ + I  + CLL +          +LPG+ +++D QC++ FG  Y  C   R+ D  C+ L+C  P+    C     PP+DGT CA  +WC KG C+ +        DG +  W+ + SC+  CG GV  R R+C++P PI GG+ C G   E+++C +   C  H  FED R   C
Sbjct:  258 IEVLLGVDDSVVRFHG-KEHVQNYLLTLMNIVNEIYHDESLGVHINVVLVRMIMLGYAKSISL-IERGNPSRSLENVCRWASQQQRSDLNHSEHHDHAIFLTRQDFGPAGMQGYAPVTGMCHPVRSCTLNHEDGFSSAFVVAHETGHVLGMEHDGQGNRCGDETAMGSVMAPLVQAAFHRYHWSRCSGQELKRYIHSYDCLLDDPFDHDWPKLPELPGINYSMDEQCRFDFGVGYKMCTAFRTFDP-CKQLWCSHPDNPYFCKTKKGPPLDGTECAAGKWCYKGHCM-WKNANQQKQDGNWGSWTKFGSCSRTCGTGVRFRTRQCNNPMPINGGQDCPGVNFEYQLC-NTEECQKH--FEDFRAQQC 617
The following BLAST results are available for this feature:
BLAST of TCONS_00053160-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
ATS31.311e-6234.33A disintegrin and metalloproteinase with thrombosp... [more]
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