TCONS_00051018-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00051018-protein
Unique NameTCONS_00051018-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length381

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00051018-protein ID=TCONS_00051018-protein|Name=TCONS_00051018-protein|organism=Clytia hemisphaerica|type=polypeptide|length=381bp
ACACSKQHVRSFETQVDTFAVFLYTPPVEIQFVIENETEKSHLKMASTEP
LRVCVTGAAGQIAYSLLYSIGNGDVFGKSQPITLLLLDIPPMMPVLEGVV
MELQDCSLPLLHEVVGTADPNVSFNNVDAAILVGAMPRREGMERKDLLKA
NAKIFEDQGKALDQYAKKTVKILVVGNPANTNCLIASKCAPSIPKENFSC
LTKLDQNRAISQVAMRLGIKTCDVSKVIIWGNHSSTQYPDVQHGFVNLNG
QAVPITEAVKDDNWIQGEFLRTVQTRGAAIIKARKLSSAMSAAKAICDHM
RVWWFGTAEGEYMSMGVITDGTHYGIPEDIVYSFPLTIGAGHKYTIVDGL
EINAFSRQKMDLSAKELVEERDVALAFLKKE
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_032340XLOC_032340Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00051018TCONS_00051018Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001557L-lactate/malate_DH
IPR022383Lactate/malate_DH_C
IPR001236Lactate/malate_DH_N
IPR010945Malate_DH_type2
IPR011274Malate_DH_NAD-dep_euk
IPR001252Malate_DH_AS
IPR015955Lactate_DH/Glyco_Ohase_4_C
IPR016040NAD(P)-bd_dom
Vocabulary: Biological Process
TermDefinition
GO:0055114oxidation-reduction process
GO:0019752carboxylic acid metabolic process
GO:0006108malate metabolic process
GO:0005975carbohydrate metabolic process
Vocabulary: Molecular Function
TermDefinition
GO:0016616oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0016491oxidoreductase activity
GO:0016615malate dehydrogenase activity
GO:0030060L-malate dehydrogenase activity
GO:0003824catalytic activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0005975 carbohydrate metabolic process
biological_process GO:0019752 carboxylic acid metabolic process
biological_process GO:0006108 malate metabolic process
biological_process GO:0055114 oxidation-reduction process
molecular_function GO:0003824 catalytic activity
molecular_function GO:0030060 L-malate dehydrogenase activity
molecular_function GO:0016615 malate dehydrogenase activity
molecular_function GO:0016491 oxidoreductase activity
molecular_function GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001557L-lactate/malate dehydrogenasePIRSFPIRSF000102Lac_mal_DHcoord: 47..378
e-value: 4.0E-65
score: 217.9
NoneNo IPR availableGENE3D3.90.110.10coord: 202..376
e-value: 1.3E-47
score: 161.2
NoneNo IPR availableGENE3D3.40.50.720coord: 52..201
e-value: 1.0E-24
score: 86.6
IPR022383Lactate/malate dehydrogenase, C-terminalPFAMPF02866Ldh_1_Ccoord: 202..377
e-value: 1.2E-37
score: 129.3
IPR001236Lactate/malate dehydrogenase, N-terminalPFAMPF00056Ldh_1_Ncoord: 52..198
e-value: 2.5E-36
score: 124.8
IPR010945Malate dehydrogenase, type 2TIGRFAMTIGR01759TIGR01759coord: 49..374
e-value: 1.2E-149
score: 495.7
IPR010945Malate dehydrogenase, type 2HAMAPMF_01517Malate_dehydrog_2coord: 47..378
score: 47.49
IPR011274Malate dehydrogenase, NAD-dependent, cytosolicTIGRFAMTIGR01758TIGR01758coord: 52..376
e-value: 1.1E-153
score: 509.4
IPR011274Malate dehydrogenase, NAD-dependent, cytosolicCDDcd01336MDH_cytoplasmic_cytosoliccoord: 49..375
e-value: 0.0
score: 619.642
IPR001252Malate dehydrogenase, active sitePROSITEPS00068MDHcoord: 201..213
IPR015955Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminalSUPERFAMILY56327LDH C-terminal domain-likecoord: 202..379
IPR016040NAD(P)-binding domainSUPERFAMILY51735NAD(P)-binding Rossmann-fold domainscoord: 49..200

Blast
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BLAST of TCONS_00051018-protein vs. Swiss-Prot (Human)
Match: MDHC (Malate dehydrogenase, cytoplasmic OS=Homo sapiens GN=MDH1 PE=1 SV=4)

HSP 1 Score: 493.812 bits (1270), Expect = 2.462e-176
Identity = 230/331 (69.49%), Postives = 277/331 (83.69%), Query Frame = 0 
Query:   48 TEPLRVCVTGAAGQIAYSLLYSIGNGDVFGKSQPITLLLLDIPPMMPVLEGVVMELQDCSLPLLHEVVGTADPNVSFNNVDAAILVGAMPRREGMERKDLLKANAKIFEDQGKALDQYAKKTVKILVVGNPANTNCLIASKCAPSIPKENFSCLTKLDQNRAISQVAMRLGIKTCDVSKVIIWGNHSSTQYPDVQHGFVNLNGQAVPITEAVKDDNWIQGEFLRTVQTRGAAIIKARKLSSAMSAAKAICDHMRVWWFGTAEGEYMSMGVITDGTHYGIPEDIVYSFPLTIGAGHKYTIVDGLEINAFSRQKMDLSAKELVEERDVALAFL 378
            +EP+RV VTGAAGQIAYSLLYSIGNG VFGK QPI L+LLDI PMM VL+GV+MELQDC+LPLL +V+ T   +V+F ++D AILVG+MPRREGMERKDLLKAN KIF+ QG ALD+YAKK+VK++VVGNPANTNCL ASK APSIPKENFSCLT+LD NRA +Q+A++LG+   DV  VIIWGNHSSTQYPDV H  V L G+ V + EA+KDD+W++GEF+ TVQ RGAA+IKARKLSSAMSAAKAICDH+R  WFGT EGE++SMGVI+DG  YG+P+D++YSFP+ I     +  V+GL IN FSR+KMDL+AKEL EE++ A  FL
Sbjct:    2 SEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLDITPMMGVLDGVLMELQDCALPLLKDVIATDKEDVAFKDLDVAILVGSMPRREGMERKDLLKANVKIFKSQGAALDKYAKKSVKVIVVGNPANTNCLTASKSAPSIPKENFSCLTRLDHNRAKAQIALKLGVTANDVKNVIIWGNHSSTQYPDVNHAKVKLQGKEVGVYEALKDDSWLKGEFVTTVQQRGAAVIKARKLSSAMSAAKAICDHVRDIWFGTPEGEFVSMGVISDGNSYGVPDDLLYSFPVVI-KNKTWKFVEGLPINDFSREKMDLTAKELTEEKESAFEFL 331
The following BLAST results are available for this feature:
BLAST of TCONS_00051018-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
MDHC2.462e-17669.49Malate dehydrogenase, cytoplasmic OS=Homo sapiens ... [more]
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