TCONS_00039089-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00039089-protein
Unique NameTCONS_00039089-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length276

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00039089-protein ID=TCONS_00039089-protein|Name=TCONS_00039089-protein|organism=Clytia hemisphaerica|type=polypeptide|length=276bp
ELNLEVDKQLCLSPFFQQTKSQTLIMSVFIQQKWKDETLTWKKEDYGGHI
KSINVDPSRVWKPDIVLYSNADEDKTFGGNLDRLNTRVRLFYDGNITWLA
PIILRSQCSIDVTYFPFDTQNCTLKFGSWTYERARLNLRDGGIKMAQTKE
YEANSEWKLISTYNMRHDIEYPCCKDEFYPDITFHIVIARRSLFYLCNLI
FPMTVIGMLTMLSFLLPAESGERISLAITLLLAMTVFMLVVADIIPATSD
VIPLVGIFFSASMIEMVIMIVVLCYI
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_023537XLOC_023537Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00039089TCONS_00039089Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR006201Neur_channel
IPR006202Neur_chan_lig-bd
IPR006029Neurotrans-gated_channel_TM
IPR018000Neurotransmitter_ion_chnl_CS
Vocabulary: Cellular Component
TermDefinition
GO:0016021integral component of membrane
Vocabulary: Biological Process
TermDefinition
GO:0006811ion transport
Vocabulary: Molecular Function
TermDefinition
GO:0005216ion channel activity
GO:0005230extracellular ligand-gated ion channel activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006811 ion transport
cellular_component GO:0016021 integral component of membrane
molecular_function GO:0005230 extracellular ligand-gated ion channel activity
molecular_function GO:0005216 ion channel activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR006201Neurotransmitter-gated ion-channelPRINTSPR00252NRIONCHANNELcoord: 186..198
score: 31.12
coord: 108..122
score: 57.19
coord: 25..41
score: 32.18
coord: 59..70
score: 43.1
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainGENE3D2.70.170.10coord: 5..197
e-value: 2.8E-53
score: 180.1
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainPFAMPF02931Neur_chan_LBDcoord: 19..191
e-value: 1.2E-46
score: 158.8
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainSUPERFAMILY63712Nicotinic receptor ligand binding domain-likecoord: 19..191
NoneNo IPR availableGENE3D1.20.58.390coord: 198..276
e-value: 6.4E-23
score: 80.5
IPR006029Neurotransmitter-gated ion-channel transmembrane domainPFAMPF02932Neur_chan_membcoord: 199..273
e-value: 2.0E-18
score: 67.3
IPR006029Neurotransmitter-gated ion-channel transmembrane domainSUPERFAMILY90112Neurotransmitter-gated ion-channel transmembrane porecoord: 193..273
IPR018000Neurotransmitter-gated ion-channel, conserved sitePROSITEPS00236NEUROTR_ION_CHANNELcoord: 108..122

Blast
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BLAST of TCONS_00039089-protein vs. Swiss-Prot (Human)
Match: ACHA3 (Neuronal acetylcholine receptor subunit alpha-3 OS=Homo sapiens GN=CHRNA3 PE=1 SV=4)

HSP 1 Score: 224.557 bits (571), Expect = 3.396e-70
Identity = 112/256 (43.75%), Postives = 166/256 (64.84%), Query Frame = 0 
Query:   21 SQTLIMSVFIQQKWKDETLTWKKEDYGGHIKSINVDPSRVWKPDIVLYSNADEDKTFGGNLDRLNTRVRLFYDGNITWLAPIILRSQCSIDVTYFPFDTQNCTLKFGSWTYERARLNLRDGGIKMAQTKEYEANSEWKLISTYNMRHDIEYPCCKDEFYPDITFHIVIARRSLFYLCNLIFPMTVIGMLTMLSFLLPAESGERISLAITLLLAMTVFMLVVADIIPATSDVIPLVGIFFSASMIEMVIMIVVLCYI 276
            +Q +  +++++Q W D  L W   DYGG  + + V   ++WKPDIVLY+NA  D           T+  L Y G +TW+ P I +S C IDVTYFPFD QNCT+KFGSW+Y++A+++L   G  M   K+Y  + EW +I     +HDI+Y CC +E YPDIT+ + I R  LFY  NLI P  +I  LT+L F LP++ GE+++L I++LL++TVF+LV+ + IP+TS VIPL+G +   +MI + + IV+  ++
Sbjct:   78 NQIMETNLWLKQIWNDYKLKWNPSDYGGA-EFMRVPAQKIWKPDIVLYNNAVGDFQVDDK-----TKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIGSSM-NLKDYWESGEWAIIKAPGYKHDIKYNCC-EEIYPDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFV 325
The following BLAST results are available for this feature:
BLAST of TCONS_00039089-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
ACHA33.396e-7043.75Neuronal acetylcholine receptor subunit alpha-3 OS... [more]
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