TCONS_00028501-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00028501-protein
Unique NameTCONS_00028501-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length229

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00028501-protein ID=TCONS_00028501-protein|Name=TCONS_00028501-protein|organism=Clytia hemisphaerica|type=polypeptide|length=229bp
SGVHECGDFHACIQILITRNEKVHSAQTKIQQHGKLQCASSTPYNSTPNQ
RDRVNLSNEEILQLCKEKKLALHSLEATLNDHKRAVEIRRSFVTAEIGKE
ADALDDLPYENYNYEKVYGVCCENVIGYCTIPLGVAGPLLLDNNKFYVPM
ATTEGCLVASTNRGCSALRASGGVFSYLIGDGMTRGPVVRMASAREACLV
REWIEEQDNFVILSEAFNQSSRFTELQEI
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_016150XLOC_016150Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00028501TCONS_00028501Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR002202HMG_CoA_Rdtase
IPR023282HMG_CoA_Rdtase_N
IPR023074HMG_CoA_Rdtase_cat
IPR009029HMG_CoA_Rdtase_sub-bd_dom
IPR009023HMG_CoA_Rdtase_NAD(P)-bd_dom
Vocabulary: Biological Process
TermDefinition
GO:0055114oxidation-reduction process
GO:0015936coenzyme A metabolic process
Vocabulary: Molecular Function
TermDefinition
GO:0004420hydroxymethylglutaryl-CoA reductase (NADPH) activity
GO:0050662coenzyme binding
GO:0016616oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0015936 coenzyme A metabolic process
biological_process GO:0055114 oxidation-reduction process
molecular_function GO:0050662 coenzyme binding
molecular_function GO:0004420 hydroxymethylglutaryl-CoA reductase (NADPH) activity
molecular_function GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 65..85
IPR002202Hydroxymethylglutaryl-CoA reductase, class I/IIPRINTSPR00071HMGCOARDTASEcoord: 121..142
score: 69.41
coord: 148..168
score: 85.02
IPR002202Hydroxymethylglutaryl-CoA reductase, class I/IIPFAMPF00368HMG-CoA_redcoord: 85..229
e-value: 4.6E-44
score: 150.8
IPR002202Hydroxymethylglutaryl-CoA reductase, class I/IIPROSITEPS50065HMG_COA_REDUCTASE_4coord: 58..229
score: 43.481
IPR023282Hydroxymethylglutaryl-CoA reductase, N-terminalGENE3D1.10.3270.10coord: 54..131
e-value: 5.9E-28
score: 96.3
IPR023074Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domainGENE3D3.90.770.10coord: 132..229
e-value: 5.8E-27
score: 94.3
IPR009029Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domainSUPERFAMILY56542Substrate-binding domain of HMG-CoA reductasecoord: 48..183
IPR009023Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domainSUPERFAMILY55035NAD-binding domain of HMG-CoA reductasecoord: 182..229

Blast
[Close]
BLAST of TCONS_00028501-protein vs. Swiss-Prot (Human)
Match: HMDH (3-hydroxy-3-methylglutaryl-coenzyme A reductase OS=Homo sapiens GN=HMGCR PE=1 SV=1)

HSP 1 Score: 190.66 bits (483), Expect = 6.505e-56
Identity = 89/174 (51.15%), Postives = 118/174 (67.82%), Query Frame = 0 
Query:   56 LSNEEILQLCKEKKLALHSLEATLNDHKRAVEIRRSFVTAEIGKEADALDDLPYENYNYEKVYGVCCENVIGYCTIPLGVAGPLLLDNNKFYVPMATTEGCLVASTNRGCSALRASGGVFSYLIGDGMTRGPVVRMASAREACLVREWIEEQDNFVILSEAFNQSSRFTELQEI 229
            LS+ EI+QL   K +  + LE  +  H+R V IRR  ++ ++  E  +L  LPY +YNY  V G CCENVIGY  IP+GVAGPL LD  +F VPMATTEGCLVASTNRGC A+   GG  S ++ DGMTRGPVVR+  A ++  V+ W+E  + F ++ EAF+ +SRF  LQ++
Sbjct:  462 LSDAEIIQLVNAKHIPAYKLETLMETHERGVSIRRQLLSKKL-SEPSSLQYLPYRDYNYSLVMGACCENVIGYMPIPVGVAGPLCLDEKEFQVPMATTEGCLVASTNRGCRAIGLGGGASSRVLADGMTRGPVVRLPRACDSAEVKAWLETSEGFAVIKEAFDSTSRFARLQKL 634
The following BLAST results are available for this feature:
BLAST of TCONS_00028501-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
HMDH6.505e-5651.153-hydroxy-3-methylglutaryl-coenzyme A reductase OS... [more]
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