TCONS_00023124-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00023124-protein
Unique NameTCONS_00023124-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length994

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00023124-protein ID=TCONS_00023124-protein|Name=TCONS_00023124-protein|organism=Clytia hemisphaerica|type=polypeptide|length=994bp
MDFKIVKMRNFHLVLFSLVMFKGLLSMNDLTDKDDVKHTIQRRSSNSDVC
DDNRPCQIPEFRTHPRNISYPIKQRLRCRAVGNPQPIITWRKLNVNSNAM
ADTSIDPQNKHYRISTERKRIKDGNFKGYREMVVSTMNIESWNSDTNPAV
YACVAKNQEGETLSKKSFVTKEGAGFPNSHGVPGDKNFKLEEKCLPLKNS
SACWGYLDPTRSVYTEGNIEVKEDMLQTIKKVLAMNQHKISNKCKPLVLP
FLCYFNMPYCSHGNNLKRRPQMICKQDCTLLSKTDCQKEFEFAQKDRSLT
AVVPQSCDELPSTNCTKTFQEMDRVRNYLEQMKAMASLLPKVGTKVNSGD
FCYFDKGEEYLGIENRTVTGLSCLRWKNSNHNFCRNPSNVLRERPWCFTD
NNGAFAYCNIQQCAIPDSQTSSILYTIIPCLLFALILSLAIITLAWRRHK
EHYYQATPGSPKQLVPRVNPKILELNREDLCDFRMLGDGNIGRVYTADYT
GSKDGRTFTASVAVKAIIEKASNQQIQDFVREAETRANFKHENVIALIGV
ISKEEPLSLIYEYTEFGDLHEYLLRHSPNFSDAHAADNCGPLEFNDLFAI
AKQIANGMSYLSSHAFVHKDLAARNCLVAENGIVKISDFSGLCDMYAGDY
YRAPGRPPLPVRWMAPEAISQMNFTTASDVWSFSILLWEVFSYGSRPFFG
LSNYQAMEHILDSKLLPCPDHCPKPIFEIMAECWVVDPNDRPAFPEIYNN
LKSISDVASTQSSGPRRQYTPDIGGNSSHGADIPLHLSDVKMHSSVHSIT
PPSVRKCQRDLPLGSYRSSMHSRHSSNPSVHSIGHHPGSIHSSSMVSQPR
SVPSMMMNNIQRMAPARPHNNHHSLPRDGYHSLNRGGDHHSQNNYLIDNQ
YPMHAMDHHSISSASSHRMHPMGAYSSYTPSYPPSLTGPPASSVFSRQSS
DHPSSKTSESIKSYVSSSQPQRHHSHHSNHHVGHHGNGNAQVYL
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_012995XLOC_012995Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00023124TCONS_00023124Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001245Ser-Thr/Tyr_kinase_cat_dom
IPR000001Kringle
IPR013783Ig-like_fold
IPR020067Frizzled_dom
IPR008266Tyr_kinase_AS
IPR007110Ig-like_dom
IPR000719Prot_kinase_dom
IPR013806Kringle-like
IPR011009Kinase-like_dom
Vocabulary: Molecular Function
TermDefinition
GO:0004672protein kinase activity
GO:0005515protein binding
GO:0005524ATP binding
Vocabulary: Biological Process
TermDefinition
GO:0006468protein phosphorylation
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006468 protein phosphorylation
molecular_function GO:0005524 ATP binding
molecular_function GO:0005515 protein binding
molecular_function GO:0004672 protein kinase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPRINTSPR00109TYRKINASEcoord: 610..628
score: 61.11
coord: 659..669
score: 65.2
coord: 722..744
score: 41.79
coord: 678..700
score: 56.75
coord: 561..574
score: 38.49
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPFAMPF07714Pkinase_Tyrcoord: 484..751
e-value: 3.8E-81
score: 272.1
IPR000001KringleSMARTSM00130KR_2coord: 350..415
e-value: 5.1E-11
score: 52.6
IPR000001KringlePROSITEPS50070KRINGLE_2coord: 351..413
score: 13.773
NoneNo IPR availableGENE3D2.40.20.10coord: 325..378
e-value: 0.0023
score: 17.9
NoneNo IPR availableGENE3D3.30.200.20coord: 464..563
e-value: 4.9E-16
score: 58.0
NoneNo IPR availableGENE3D1.10.510.10coord: 564..973
e-value: 1.6E-44
score: 151.5
NoneNo IPR availableGENE3D2.40.20.10coord: 379..424
e-value: 2.7E-8
score: 33.8
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 866..895
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 814..850
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 758..777
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 934..994
NoneNo IPR availableCDDcd00192PTKccoord: 484..752
e-value: 8.29555E-110
score: 341.826
IPR013783Immunoglobulin-like foldGENE3D2.60.40.10coord: 56..171
e-value: 1.5E-7
score: 31.1
IPR020067Frizzled domainPFAMPF01392Fzcoord: 220..314
e-value: 2.4E-6
score: 28.1
IPR020067Frizzled domainGENE3D1.10.2000.10coord: 186..324
e-value: 5.9E-10
score: 39.0
IPR020067Frizzled domainPROSITEPS50038FZcoord: 189..318
score: 13.967
IPR008266Tyrosine-protein kinase, active sitePROSITEPS00109PROTEIN_KINASE_TYRcoord: 616..628
IPR007110Immunoglobulin-like domainPROSITEPS50835IG_LIKEcoord: 59..164
score: 8.938
IPR007110Immunoglobulin-like domainSUPERFAMILY48726Immunoglobulincoord: 123..169
coord: 59..92
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 480..754
score: 34.153
IPR013806Kringle-like foldSUPERFAMILY57440Kringle-likecoord: 350..422
IPR011009Protein kinase-like domainSUPERFAMILY56112Protein kinase-like (PK-like)coord: 468..759

Blast
[Close]
BLAST of TCONS_00023124-protein vs. Swiss-Prot (Human)
Match: ROR2 (Tyrosine-protein kinase transmembrane receptor ROR2 OS=Homo sapiens GN=ROR2 PE=1 SV=2)

HSP 1 Score: 331.257 bits (848), Expect = 2.625e-98
Identity = 230/790 (29.11%), Postives = 363/790 (45.95%), Query Frame = 0 
Query:   39 TIQRRSSNSDVCDDNRPCQ--------IPEFRTHPRNISYPIKQR---------LRCRAVGNPQPIITWRKLNVNSNAMADTSIDPQNKHYRISTERKRIKDGNFKGYREMVVSTMNIESWNSDTNPAVYACVAKNQEGETLSKKSFVTKEGAGFPNSHGVPGDKNFKLEEKCLPLKNSSACWGYLDPTRSVYTEGNIEVKEDMLQTIKKVLAM--NQHKISNKCKPLVLPFLCYFNMPYCSHGNNLKRRPQMICKQDCTLLSKTDCQKEFEFAQKD-RSLTAVVPQSCDELP------STNCTKTFQEMDRVRNYLEQMKAMASLLPKVGTKVNSGDFCYFDKGEEYLGIENRTVTGLSCLRWK-----------------NSNHNFCRNPSNVLRERPWCFTDN-NGAFAYCNIQQCAIPDSQTSSILYTIIPCLLFALILSLAIITLAWRRHKEHYYQATP------GSPKQ--LVPRVN----PKILELNREDLCDFRMLGDGNIGRVYTADYTGSKDGRTFTASVAVKAIIEKASNQQIQDFVREAETRANFKHENVIALIGVISKEEPLSLIYEYTEFGDLHEYLLRHSPNFSDAHAADN----CGPLEFNDLFAIAKQIANGMSYLSSHAFVHKDLAARNCLVAENGIVKISDFSGLCDMYAGDYYRAPGRPPLPVRWMAPEAISQMNFTTASDVWSFSILLWEVFSYGSRPFFGLSNYQAMEHILDSKLLPCPDHCPKPIFEIMAECWVVDPNDRPAFPEIYNNLKSISDV----ASTQSSG 764
            ++ R S   +V D N P          IP  + +  N   P+            L C+  GNP P + W K                N    +   R+ I      G R      + I+  ++ T+   Y CVA N      +      + G     +H    D  +  +  C P +   AC  ++   R++Y + +++++ ++   I     M      +S++C    +P  C+F  P C    +   +P+ +C+ +C +L    C++E+  A+ +   L  +    C+ LP      + NC +     +R+  Y +                     CY   G +Y G  + T +G  C  W                     H +CRNP   + E PWCFT N N     C++  C+  DS    ILY ++P +   L+++     +   R+K+    +TP       SP Q   +P +N     K+ E++   +     LG+   G+VY     G   G   T +VA+K + +KA     ++F  EA  RA  +H NV+ L+GV++K++PLS+I+ Y   GDLHE+L+  SP+ SD  + D+       LE  D   +  QIA GM YLSSH  VHKDLA RN LV +   VKISD     ++YA DYY+  G   LP+RWMAPEAI    F+  SD+WS+ ++LWEVFSYG +P+ G SN   +E I + ++LPCPD CP  ++ +M ECW   P+ RP F +I++ L++  ++    +S Q+SG
Sbjct:   27 SVSRTSGEVEVLDPNDPLGPLDGQDGPIPTLKGYFLNFLEPVNNITIVQGQTAILHCKVAGNPPPNVRWLK----------------NDAPVVQEPRRIIIRKTEYGSR------LRIQDLDT-TDTGYYQCVATNGMKTITATGVLFVRLGPTHSPNHNFQDD--YHEDGFCQPYRGI-ACARFIG-NRTIYVD-SLQMQGEIENRITAAFTMIGTSTHLSDQCSQFAIPSFCHFVFPLCD-ARSRTPKPRELCRDECEVLESDLCRQEYTIARSNPLILMRLQLPKCEALPMPESPDAANCMRIGIPAERLGRYHQ---------------------CYNGSGMDYRGTASTTKSGHQCQPWALQHPHSHHLSSTDFPELGGGHAYCRNPGGQM-EGPWCFTQNKNVRMELCDVPSCSPRDSSKMGILYILVPSIAIPLVIACLFFLVCMCRNKQKASASTPQRRQLMASPSQDMEMPLINQHKQAKLKEISLSAVRFMEELGEDRFGKVYKGHLFGPAPGEQ-TQAVAIKTLKDKAEGPLREEFRHEAMLRARLQHPNVVCLLGVVTKDQPLSMIFSYCSHGDLHEFLVMRSPH-SDVGSTDDDRTVKSALEPPDFVHLVAQIAAGMEYLSSHHVVHKDLATRNVLVYDKLNVKISDLGLFREVYAADYYKLLGNSLLPIRWMAPEAIMYGKFSIDSDIWSYGVVLWEVFSYGLQPYCGYSNQDVVEMIRNRQVLPCPDDCPAWVYALMIECWNEFPSRRPRFKDIHSRLRAWGNLSNYNSSAQTSG 763
The following BLAST results are available for this feature:
BLAST of TCONS_00023124-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
ROR22.625e-9829.11Tyrosine-protein kinase transmembrane receptor ROR... [more]
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