TCONS_00022141-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00022141-protein
Unique NameTCONS_00022141-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length251

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00022141-protein ID=TCONS_00022141-protein|Name=TCONS_00022141-protein|organism=Clytia hemisphaerica|type=polypeptide|length=251bp
PKIMIVAFEVPEIWKDASHGKIKVENPIVELDGDEMTRIIWHKIKGELIL
PYLDIDCKYYDLGLPYRDETNDQVTVDAAEAILKYNVGVKCATITPDEER
VTEFNLKEMWRSPNGTIRNILGGTVFREPIMCTNVPRLVPGWVEPIVIGR
HAHGDQYKAQDVVVKGAGKFEIQFTPKDGSEKTTVDVFDFDGSGGCIMGM
YNTDESIRDFAHSCFQYALMKKWPLYMSTKNTILKRYDGRFKDIFQDIFE
E
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_012420XLOC_012420Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00022141TCONS_00022141Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR024084IsoPropMal-DH-like_dom
IPR004790Isocitrate_DH_NADP
Vocabulary: Biological Process
TermDefinition
GO:0055114oxidation-reduction process
GO:0006102isocitrate metabolic process
Vocabulary: Molecular Function
TermDefinition
GO:0016616oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0004450isocitrate dehydrogenase (NADP+) activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006102 isocitrate metabolic process
biological_process GO:0055114 oxidation-reduction process
molecular_function GO:0004450 isocitrate dehydrogenase (NADP+) activity
molecular_function GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR024084Isopropylmalate dehydrogenase-like domainSMARTSM01329Iso_dh_2coord: 27..251
e-value: 2.9E-13
score: 1.9
IPR024084Isopropylmalate dehydrogenase-like domainPFAMPF00180Iso_dhcoord: 23..250
e-value: 1.1E-34
score: 120.0
IPR004790Isocitrate dehydrogenase NADP-dependentTIGRFAMTIGR00127TIGR00127coord: 21..250
e-value: 1.8E-128
score: 426.5
NoneNo IPR availableGENE3D3.40.718.10coord: 19..251
e-value: 6.4E-78
score: 261.8
NoneNo IPR availableSUPERFAMILY53659Isocitrate/Isopropylmalate dehydrogenase-likecoord: 20..251

Blast
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BLAST of TCONS_00022141-protein vs. Swiss-Prot (Human)
Match: IDHP (Isocitrate dehydrogenase [NADP], mitochondrial OS=Homo sapiens GN=IDH2 PE=1 SV=2)

HSP 1 Score: 352.443 bits (903), Expect = 3.420e-121
Identity = 166/231 (71.86%), Postives = 193/231 (83.55%), Query Frame = 0 
Query:   21 KIKVENPIVELDGDEMTRIIWHKIKGELILPYLDIDCKYYDLGLPYRDETNDQVTVDAAEAILKYNVGVKCATITPDEERVTEFNLKEMWRSPNGTIRNILGGTVFREPIMCTNVPRLVPGWVEPIVIGRHAHGDQYKAQDVVVKGAGKFEIQFTPKDGSEKTTVDVFDFDGSGGCIMGMYNTDESIRDFAHSCFQYALMKKWPLYMSTKNTILKRYDGRFKDIFQDIFEE 251
            +IKV  P+VE+DGDEMTRIIW  IK +LILP++DI  KY+DLGLP RD+T+DQVT+D+A A  KY+V VKCATITPDE RV EF LK+MW+SPNGTIRNILGGTVFREPI+C N+PRLVPGW +PI IGRHAHGDQYKA D V   AG F++ FTPKDGS     +V++F  +GG  MGMYNTDESI  FAHSCFQYA+ KKWPLYMSTKNTILK YDGRFKDIFQ+IF++
Sbjct:   43 RIKVAKPVVEMDGDEMTRIIWQFIKEKLILPHVDIQLKYFDLGLPNRDQTDDQVTIDSALATQKYSVAVKCATITPDEARVEEFKLKKMWKSPNGTIRNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRAGTFKMVFTPKDGSGVKEWEVYNFP-AGGVGMGMYNTDESISGFAHSCFQYAIQKKWPLYMSTKNTILKAYDGRFKDIFQEIFDK 272
The following BLAST results are available for this feature:
BLAST of TCONS_00022141-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
IDHP3.420e-12171.86Isocitrate dehydrogenase [NADP], mitochondrial OS=... [more]
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