TCONS_00022120-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00022120-protein
Unique NameTCONS_00022120-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length578

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00022120-protein ID=TCONS_00022120-protein|Name=TCONS_00022120-protein|organism=Clytia hemisphaerica|type=polypeptide|length=578bp
MASEEQLEELEAIQAIFMDEYKDHSKKNCSPEFTIQLVPLQSTIAKDVHA
RLGLRVKFTTTYPNDPPIFSFEDTKGLSDEDLKSLKKEIMTQAEELCGEV
MILQLTHHIQEFLYRHNKPSLSFFEQMVQNQMKQEELQNLEQQKIEAERV
AQDREQDENVIRQVEEELKKRTEVKRKRQVSQCQQSSPQQSSLFVNKVET
IPRKLPFKCSQDRQKFFVYQFKDGNKKVFCSSCIGHFYVGACTVLAIDES
DGNKLSLTEWKWKSQQSAHHQQQKKKVHFTSSSGSSGGEKQIDDQAKQIQ
SITQEFNYLKSKVNYGGLINYHALDFDHSATNISAKLLSDSITGLCLASY
LQEDGLPLSLLHHICRQIVDGLYFLHSKSVVHHNLNLETTFINEQNEVTL
SGYAMVRRICDLCISPSSSSSFNDKTEEEEQNGGRGKLLFRQDMKAGKKG
DIYNMGLIALSLYQGHSLIQLPIDFPEDLPDALLSFLKSCLDVEEDKRST
AAQLLQHAFICDKIIDNPKTKHTQQNNGASKNDHSESNXPGVKCLQILIG
KKHHHQEASQTQTKIAEESSKSQQQQQQ
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_012404XLOC_012404Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00022120TCONS_00022120Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000719Prot_kinase_dom
IPR006575RWD-domain
IPR016135UBQ-conjugating_enzyme/RWD
IPR011009Kinase-like_dom
Vocabulary: Molecular Function
TermDefinition
GO:0004672protein kinase activity
GO:0005524ATP binding
GO:0005515protein binding
Vocabulary: Biological Process
TermDefinition
GO:0006468protein phosphorylation
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006468 protein phosphorylation
molecular_function GO:0005524 ATP binding
molecular_function GO:0005515 protein binding
molecular_function GO:0004672 protein kinase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 130..174
NoneNo IPR availableGENE3D1.10.510.10coord: 343..578
e-value: 3.0E-23
score: 81.6
IPR000719Protein kinase domainSMARTSM00220serkin_6coord: 221..510
e-value: 3.4E-6
score: -47.5
IPR000719Protein kinase domainPFAMPF00069Pkinasecoord: 300..510
e-value: 7.5E-11
score: 41.8
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 228..510
score: 14.563
IPR006575RWD domainSMARTSM00591RWD2001bcoord: 8..116
e-value: 6.6E-23
score: 92.1
IPR006575RWD domainPFAMPF05773RWDcoord: 4..113
e-value: 1.5E-21
score: 76.7
IPR006575RWD domainPROSITEPS50908RWDcoord: 8..116
score: 22.606
IPR016135Ubiquitin-conjugating enzyme/RWD-likeGENE3D3.10.110.10coord: 2..127
e-value: 3.0E-27
score: 94.7
IPR016135Ubiquitin-conjugating enzyme/RWD-likeSUPERFAMILY54495UBC-likecoord: 3..119
IPR011009Protein kinase-like domainSUPERFAMILY56112Protein kinase-like (PK-like)coord: 295..512

Blast
[Close]
BLAST of TCONS_00022120-protein vs. Swiss-Prot (Human)
Match: E2AK4 (eIF-2-alpha kinase GCN2 OS=Homo sapiens GN=EIF2AK4 PE=1 SV=3)

HSP 1 Score: 108.612 bits (270), Expect = 1.604e-24
Identity = 89/291 (30.58%), Postives = 145/291 (49.83%), Query Frame = 0 
Query:  233 CIGHF-YVGACTVLAIDESDGNKLSLTEWKWKSQQSAHHQQQKKKVHFTSSSGSSGGEKQIDDQAKQIQSITQEFNYLKSKVNYGGLINYHALDFDHSATNISAKLLSDSITGLCLASYLQEDG-LPLSLLHHICRQIVDGLYFLHSKSVVHHNLNLETTFINEQNEVTLSGYAMVRRICDLCISPSSSSSFNDKTEEEEQNGGRGKLLFRQDMKAGKKGDIYNMGLIALSLYQGHSLIQLPIDFPEDLPDALLSFLKSCLDVEEDKRSTAAQLLQHAFICDKIIDNPKTK 521
            CIG    +G     A++ + G  + L EW          Q QKK   F +S      +++ID   KQIQ    EFN L  K+++  ++ Y A++      +I   +L + I+G+ LA++L   G +P+  L     Q++ GL +LHS SVVH  L+     ++ +  V ++ Y++ +R+ D+C          D  E+         L +    K GKKGD++ +GL+ LSL QG    + P+  P DLP     FLK C+ +++ +R +  QLL+H+FI      NP+ K
Sbjct:  285 CIGSDEQLGKLVYNALETATGGFVLLYEWVL--------QWQKKMGPFLTSQE----KEKIDKCKKQIQGTETEFNSL-VKLSHPNVVRYLAMNLKEQDDSIVVDILVEHISGVSLAAHLSHSGPIPVHQLRRYTAQLLSGLDYLHSNSVVHKVLSASNVLVDAEGTVKITDYSISKRLADICK--------EDVFEQTRVRFSDNALPY----KTGKKGDVWRLGLLLLSLSQGQECGEYPVTIPSDLPADFQDFLKKCVCLDDKERWSPQQLLKHSFI------NPQPK 544

HSP 2 Score: 93.5893 bits (231), Expect = 1.066e-19
Identity = 52/144 (36.11%), Postives = 86/144 (59.72%), Query Frame = 0 
Query:    9 ELEAIQAIFMDEYKDHSKKNCSP-----EFTIQLVPLQSTIAKDVHARLGLRVKFTTTYPNDPPIFSFEDTKGLSDEDLKSLKKEIMTQAEELCGEVMILQLTHHIQEFLYRHNKPSL-SFFEQMVQNQMKQEELQNLEQQKIE 146
            EL+A++AI+  +++D     C P     E  + L P Q    ++V+ ++ LRVK   TYP+  P    ++ KGLS+E +  LK  +   A++ CGEVMI +L +H+Q FL  HNKP   SF E+M++ + ++E+ + LE ++ E
Sbjct:   26 ELQALEAIYGADFQDLRPDACGPVKEPPEINLVLYP-QGLTGEEVYVKVDLRVKCPPTYPDVVPEIELKNAKGLSNESVNLLKSRLEELAKKHCGEVMIFELAYHVQSFLSEHNKPPPKSFHEEMLERRAQEEQQRLLEAKRKE 168
The following BLAST results are available for this feature:
BLAST of TCONS_00022120-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
E2AK41.604e-2430.58eIF-2-alpha kinase GCN2 OS=Homo sapiens GN=EIF2AK4... [more]
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