TCONS_00020651-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00020651-protein
Unique Name	TCONS_00020651-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	431

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00020651-protein ID=TCONS_00020651-protein|Name=TCONS_00020651-protein|organism=Clytia hemisphaerica|type=polypeptide|length=431bp
MMSIDAFLIMNWFDPRLTWNKTLYNDTDKINLRGDKIWTPDIMLINRGNP
VAKFHTELYISKVLVFNDGNAVWSNLVTLDVSCDLDVTWFPVDKQECSMK
FGSWSYDRTQLSLVFLNKPNSTTGLKSDAFNIDSGEWVIEEFEAEETIVR
FSCCPMPFSVISYTLSMSRVSLYYFMYILLPLVSLAFLFLLVFHIPADSG
ERMGFGVTILLSITVYLLVISEKLPEKSNEXLLSITVYLLVISEKLPEKS
NDAPMLGICFITIFYILIFALMMAAGTTIFARRVTKPPEWLLNLTTKGCF
KLNSDDLAARKVRPVMSKKFSCGHMRRGTVTESDFTLKSNGMLNGNGVIV
NGNCHDEADRNAIHHRRPNTPKVFEQDNPMERTIEEMEDQYNDDWIKICR
ALDKKLFIFFLIVIILIPIIVTVSLDKTGLA

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_011583	XLOC_011583	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00020651	TCONS_00020651	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR006201	Neur_channel
IPR006202	Neur_chan_lig-bd
IPR006029	Neurotrans-gated_channel_TM
IPR018000	Neurotransmitter_ion_chnl_CS

Vocabulary: **Cellular Component**
Term	Definition
GO:0016021	integral component of membrane

Vocabulary: **Biological Process**
Term	Definition
GO:0006811	ion transport

Vocabulary: **Molecular Function**
Term	Definition
GO:0005216	ion channel activity
GO:0005230	extracellular ligand-gated ion channel activity

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0006811	ion transport
cellular_component	GO:0016021	integral component of membrane
molecular_function	GO:0005230	extracellular ligand-gated ion channel activity
molecular_function	GO:0005216	ion channel activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR006201	Neurotransmitter-gated ion-channel	PRINTS	PR00252	NRIONCHANNEL	coord: 83..97 score: 47.42 coord: 165..177 score: 23.56 coord: 3..19 score: 33.14 coord: 36..47 score: 47.66
None	No IPR available	GENE3D	1.20.58.390		coord: 175..229 e-value: 1.4E-14 score: 53.4
None	No IPR available	GENE3D	1.20.58.390		coord: 230..426 e-value: 2.5E-13 score: 49.4
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	GENE3D	2.70.170.10		coord: 1..174 e-value: 4.3E-44 score: 150.0
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	PFAM	PF02931	Neur_chan_LBD	coord: 2..169 e-value: 1.0E-37 score: 129.6
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	SUPERFAMILY	63712	Nicotinic receptor ligand binding domain-like	coord: 2..169
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain	PFAM	PF02932	Neur_chan_memb	coord: 179..228 e-value: 1.8E-12 score: 47.8
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain	SUPERFAMILY	90112	Neurotransmitter-gated ion-channel transmembrane pore	coord: 232..421
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain	SUPERFAMILY	90112	Neurotransmitter-gated ion-channel transmembrane pore	coord: 172..229
IPR018000	Neurotransmitter-gated ion-channel, conserved site	PROSITE	PS00236	NEUROTR_ION_CHANNEL	coord: 83..97

Blast

[Close]

BLAST of TCONS_00020651-protein vs. Swiss-Prot (Human)
Match: ACHA3 (Neuronal acetylcholine receptor subunit alpha-3 OS=Homo sapiens GN=CHRNA3 PE=1 SV=4)

HSP 1 Score: 162.155 bits (409), Expect = 1.383e-44
Identity = 121/438 (27.63%), Postives = 205/438 (46.80%), Query Frame = 0

Query:    1 MMSIDAFLIMNWFDPRLTWNKTLYNDTDKINLRGDKIWTPDIMLINRGNPVAKFHTELYISKVLVFNDGNAVWSNLVTLDVSCDLDVTWFPVDKQECSMKFGSWSYDRTQLSLVFLNKPNSTTGLKSDAFNIDSGEWVIEEFEAEETIVRFSCCPMPFSVISYTLSMSRVSLYYFMYILLPLVSLAFLFLLVFHIPADSGERMGFGVTILLSITVYLLVISEKLPEKS------NEXLL----------SITVYLLVISEKLPEKSNDAPMLGICFITIFYILIFALMMAAGTTIFARRVTKP-PEWLLNLTTKGCFKLNSDDLAARKVRPVMSKKFSCGHMRRGTVTESDFTLKSNGMLNGNGVIVNGNCHDEADRNAIHHRRPNTPKVFEQDNPMERTIEEMEDQ-----YNDDWIKICRALDKKLFIFFLIVIIL 416
            +M  + +L   W D +L WN + Y   + + +   KIW PDI+L N  N V  F  +   +K L+   G   W        SC +DVT+FP D Q C+MKFGSWSYD+ ++ LV +    S+  LK      +SGEW I +    +  ++++CC   +  I+Y+L + R+ L+Y + +++P + ++FL +LVF++P+D GE++   +++LLS+TV+LLVI+E +P  S       E LL           ITV++L +  + P        +     T+F  L+  +M     T       KP P +   L+   CF   ++    ++  P         H RR  ++            N +  +   +  +  D  A+      +P++ E    ++   E M+ Q       DDW  +   +D+     F +V IL
Sbjct:   80 IMETNLWLKQIWNDYKLKWNPSDYGGAEFMRVPAQKIWKPDIVLYN--NAVGDFQVDDK-TKALLKYTGEVTWIPPAIFKSSCKIDVTYFPFDYQNCTMKFGSWSYDKAKIDLVLIG---SSMNLKD---YWESGEWAIIKAPGYKHDIKYNCCEEIYPDITYSLYIRRLPLFYTINLIIPCLLISFLTVLVFYLPSDCGEKVTLCISVLLSLTVFLLVITETIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFVLNVHYRTPTTHTMPSWVK----TVFLNLLPRVMFMTRPTSNEGNAQKPRPLYGAELSNLNCFS-RAESKGCKEGYPCQDGMCGYCHHRRIKIS------------NFSANLTRSSSSESVD--AVLSLSALSPEIKEAIQSVKYIAENMKAQNEAKEIQDDWKYVAMVIDRIFLWVFTLVCIL 489

The following BLAST results are available for this feature:

BLAST of TCONS_00020651-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00020651-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
ACHA3	1.383e-44	27.63	Neuronal acetylcholine receptor subunit alpha-3 OS...	[more]

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TCONS_00020651-protein (polypeptide) - C. hemisphaerica