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Sequence
The following sequences are available for this feature:
polypeptide sequence >TCONS_00017241-protein ID=TCONS_00017241-protein|Name=TCONS_00017241-protein|organism=Clytia hemisphaerica|type=polypeptide|length=891bp
MLQTRICCLLMLLSICSIAEADKPKLTDKSTLPKQALGGDISMSCTFESS
VPGFKLTWLKNGQPVQKDGNRVFTQMLASQQGLLVVNKLQPTDEATYTCR
GENDDGVTDATIELDLYELKPTIQKIPKVYLRPNQGINITCLNEAVPIAS
TKWMKINGLFDNNVKEHKDGVLEIIKLTNTKEIFRCTASNVAGSDQIDVE
VEIVGNSPIWIDQPKDANVTLGNTFTYTISFATSATNPKVEWFKNYLKLP
KVRYEDTWRRVGAVYTSDLYFETVDIGNAGLYRAMVNFGQISPFEKHGTL
TVWAKPEITIDEISSEDGNEMYRDEGDDVELTCIVHAYPAAKLQWEKNNT
VLITSNSDNTEVNEFRTSFTLKLPSVSETGFYTCSGVNSQGSSSATVKVN
VAAAAGGGGTSRTTIIAVVVASIVAIIIIILVAIIYVKYRERFCISNYTK
ANGQFYTDVIAGEKDVSNLEDFEKNPYAIKKNINISIKRTDRANSIGYRP
NETVKGRSLRQTLKGMSVKRPSQGAIENTYARLDTMVTQGKAIDFKSIVF
DESLGEGEYGHIYGGRIIEDESATVFKECSIKMLKDDWTAEQRRDMLAEL
RMMRRIAKHRNVITLMGWCITDDNVYVLEEYAPFGSLLEFVRAQRTIHQS
REELDQLSQEDRVDTKTLLSFASQIASGMNHLEQLQVIHRDLACRNVYLS
FEKTCKIADYGLVRDIYAENVYRKVTGGQLPVRWMAKESIFEGQYTHKSD
VWSFGILLWELVNLGKIPYPGLVRTEHLLTELEQGYHMENPGHVSTDIYL
LMSQCWNDDPSRRPSFEKLERKINGFMDEEEEVHIDLSKMLQLEIDEELN
CDDELIKSPTEDFHRPKVHFSSFREEDEDEEIKKKNQAEGC Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
This polypeptide derives from the following transcript feature(s):
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: Molecular Function
| Term | Definition |
|---|
| GO:0004672 | protein kinase activity |
| GO:0004713 | protein tyrosine kinase activity |
| GO:0005524 | ATP binding |
Vocabulary: Biological Process
| Term | Definition |
|---|
| GO:0006468 | protein phosphorylation |
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
| Category |
Term Accession |
Term Name |
| biological_process |
GO:0006468 |
protein phosphorylation |
| molecular_function |
GO:0005524 |
ATP binding |
| molecular_function |
GO:0004672 |
protein kinase activity |
| molecular_function |
GO:0004713 |
protein tyrosine kinase activity |
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
| IPR Term | IPR Description | Source | Source Term | Source Description | Alignment |
|---|
| None | No IPR available | COILS | Coil | Coil | coord: 640..660 |
| None | No IPR available | PFAM | PF13927 | Ig_3 | coord: 23..103
e-value: 2.3E-9
score: 37.7
coord: 305..388
e-value: 5.8E-11
score: 42.7 |
| None | No IPR available | GENE3D | 3.30.200.20 | | coord: 539..635
e-value: 3.8E-15
score: 55.2 |
| None | No IPR available | PIRSF | PIRSF000615 | TyrPK_CSF1-R | coord: 162..406
e-value: 3.8E-11
score: 39.8
coord: 13..182
e-value: 3.0E-5
score: 20.2
coord: 407..445
e-value: 310.0
score: -3.0
coord: 644..890
e-value: 2.5E-64
score: 215.8
coord: 546..661
e-value: 1.4E-11
score: 41.2 |
| None | No IPR available | GENE3D | 1.10.510.10 | | coord: 636..889
e-value: 1.9E-44
score: 151.3 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 867..891 |
| None | No IPR available | CDD | cd00096 | Ig | coord: 41..113
e-value: 2.01484E-7
score: 48.6395 |
| None | No IPR available | CDD | cd00192 | PTKc | coord: 554..823
e-value: 3.58106E-109
score: 337.974 |
| None | No IPR available | CDD | cd00096 | Ig | coord: 329..398
e-value: 8.63119E-9
score: 52.4915 |
| IPR001245 | Serine-threonine/tyrosine-protein kinase, catalytic domain | PRINTS | PR00109 | TYRKINASE | coord: 794..816
score: 40.13
coord: 730..740
score: 54.2
coord: 629..642
score: 43.54
coord: 681..699
score: 46.19
coord: 749..771
score: 65.02 |
| IPR001245 | Serine-threonine/tyrosine-protein kinase, catalytic domain | PFAM | PF07714 | Pkinase_Tyr | coord: 549..822
e-value: 1.2E-83
score: 280.2 |
| IPR003599 | Immunoglobulin subtype | SMART | SM00409 | IG_3c | coord: 30..117
e-value: 2.4E-5
score: 33.8
coord: 126..204
e-value: 40.0
score: 6.3
coord: 214..303
e-value: 27.0
score: 7.8
coord: 318..402
e-value: 1.3E-5
score: 34.7 |
| IPR003598 | Immunoglobulin subtype 2 | SMART | SM00408 | igc2_5 | coord: 132..193
e-value: 1.9
score: 4.5
coord: 36..106
e-value: 1.2E-5
score: 34.7
coord: 324..391
e-value: 1.5E-5
score: 34.4 |
| IPR020635 | Tyrosine-protein kinase, catalytic domain | SMART | SM00219 | tyrkin_6 | coord: 548..823
e-value: 3.0E-101
score: 352.3 |
| IPR013783 | Immunoglobulin-like fold | GENE3D | 2.60.40.10 | | coord: 122..204
e-value: 9.9E-6
score: 25.2 |
| IPR013783 | Immunoglobulin-like fold | GENE3D | 2.60.40.10 | | coord: 17..121
e-value: 4.7E-15
score: 55.0 |
| IPR013783 | Immunoglobulin-like fold | GENE3D | 2.60.40.10 | | coord: 205..307
e-value: 1.2E-7
score: 31.2 |
| IPR013783 | Immunoglobulin-like fold | GENE3D | 2.60.40.10 | | coord: 308..408
e-value: 3.0E-17
score: 62.2 |
| IPR008266 | Tyrosine-protein kinase, active site | PROSITE | PS00109 | PROTEIN_KINASE_TYR | coord: 687..699 |
| IPR017441 | Protein kinase, ATP binding site | PROSITE | PS00107 | PROTEIN_KINASE_ATP | coord: 554..577 |
| IPR007110 | Immunoglobulin-like domain | PROSITE | PS50835 | IG_LIKE | coord: 24..115
score: 12.749 |
| IPR007110 | Immunoglobulin-like domain | PROSITE | PS50835 | IG_LIKE | coord: 306..400
score: 12.241 |
| IPR007110 | Immunoglobulin-like domain | PROSITE | PS50835 | IG_LIKE | coord: 121..204
score: 7.159 |
| IPR007110 | Immunoglobulin-like domain | SUPERFAMILY | 48726 | Immunoglobulin | coord: 318..403 |
| IPR007110 | Immunoglobulin-like domain | SUPERFAMILY | 48726 | Immunoglobulin | coord: 208..309 |
| IPR007110 | Immunoglobulin-like domain | SUPERFAMILY | 48726 | Immunoglobulin | coord: 33..118 |
| IPR007110 | Immunoglobulin-like domain | SUPERFAMILY | 48726 | Immunoglobulin | coord: 124..203 |
| IPR000719 | Protein kinase domain | PROSITE | PS50011 | PROTEIN_KINASE_DOM | coord: 548..827
score: 37.389 |
| IPR011009 | Protein kinase-like domain | SUPERFAMILY | 56112 | Protein kinase-like (PK-like) | coord: 536..819 |
Blast
BLAST of TCONS_00017241-protein vs. Swiss-Prot (Human)
Match: FGFR3 (Fibroblast growth factor receptor 3 OS=Homo sapiens GN=FGFR3 PE=1 SV=1) HSP 1 Score: 247.669 bits (631), Expect = 5.300e-70 Identity = 192/632 (30.38%), Postives = 301/632 (47.63%), Query Frame = 0
Query: 219 VTLGNTFTYTISFATSATNPKVEWFKNYLKLPKVRYEDTWRRVGAVYTS----DLYFETVDIGNAGLYRAMV--NFGQISPFEKHGTLTVWAK-PEITIDEISSEDGNEMYRDEGDDVELTCIVHAYPAAKLQWEKNN---------------TVLITSNSDNTEVNEFRTSFTLKLPSVSETGFYTCSGVNSQGSSSATVKVNVAAA------AGGGGTSRTTIIAVVVASIVAIIIIILVAIIYVKYRERFCISNYTKANGQFYTDVIAGEKDVSNLEDFEKNPYAIKKNINISIKRTDRANSIGYRPNETVKGRSLRQTLKGMS-VKRPSQGAIENTYARLDTMVTQGKAIDFKSIVFDESLGEGEYGHIYGGRII--EDESATVFKECSIKMLKDDWTAEQRRDMLAELRMMRRIAKHRNVITLMGWCITDDNVYVLEEYAPFGSLLEFVRAQRTIHQSREELDQLSQEDRVDTKTLLSFASQIASGMNHLEQLQVIHRDLACRNVYLSFEKTCKIADYGLVRDIYAENVYRKVTGGQLPVRWMAKESIFEGQYTHKSDVWSFGILLWELVNLGKIPYPGLVRTEHLLTELEQGYHMENPGHVSTDIYLLMSQCWNDDPSRRPSFEKL 819
V NT + A + T P + W KN + R E R+G + L E+V + G Y +V FG I + TL V + P I + G DVE C V++ +QW K+ TVL T+ ++ T+ E +L + + G YTC NS G S + + V A A G+ I++ V + I+++ V + ++ + + G V + F +K+ +++ + +N+ R G TL +S ++ P+ E + ARL T GK LGEG +G + I + + A ++KMLKDD T + D+++E+ MM+ I KH+N+I L+G C +YVL EYA G+L EF+RA+R E+++ K L+S A Q+A GM +L + IHRDLA RNV ++ + KIAD+GL RD++ + Y+K T G+LPV+WMA E++F+ YTH+SDVWSFG+LLWE+ LG PYPG + E L L++G+ M+ P + + D+Y++M +CW+ PS+RP+F++L
Sbjct: 166 VPAANTVRFRCPAAGNPT-PSISWLKNGREF---RGE---HRIGGIKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSI---RQTYTLDVLERSPHRPILQAGLPANQTAVL--GSDVEFHCKVYSDAQPHIQWLKHVEVNGSKVGPDGTPYVTVLKTAGANTTD-KELEV-LSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVVLPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGL----------------GSPTVHKISRF-----PLKRQVSLESNASMSSNTPLVRIARLSSGEG--PTLANVSELELPADPKWELSRARL----TLGK-----------PLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIGKHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPPGLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPG-IPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQL 744
The following BLAST results are available for this feature:
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