TCONS_00016615-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00016615-protein
Unique Name	TCONS_00016615-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	510

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00016615-protein ID=TCONS_00016615-protein|Name=TCONS_00016615-protein|organism=Clytia hemisphaerica|type=polypeptide|length=510bp
MFKNITTMAKLNGIYDCMRVLLVTLLIGQQIRTIENHPSITGGSHAQNNG
QAPSAMPKPEFSSINATLLSQTFENAMKNYDKKFKPFFGEKSTNVSLEMH
VLSFNRIDESGMEYGIDFYFAQFWNDPRFIDQSKNFHPQQNFINLIGKDV
ERIWLPDVVFINSKSSRFHDVTINNRFLTIYFDTGRIIYHSRITTTAQCR
MDLRDYPFDVQTCYLAIESYGHDERTMKFDWYDQSGQNCESEGCKMIYVY
DKEMSNFDVVEAMKSTNKTTYHAERFSSATAKFTFKRRSKYFVLQVYIPC
ILIVMVTWASFWITPSAAPARTAICVTTILTLITMLGIVNANMPKVSYIK
ALDLYLFVAFIFVLLSLLEYILVLNLNVNYGGINKYGVKLPFLNHLRRKK
KHNPDHHDTNGYSNGRQRLLNGEETSETRFRSNVYKDNTKESTVLEMEKN
NNEEKPKIEEKPKPPAGTSHAGCDVISRFLFPIGFIVFNVGYWVAYMTQQ
KEFKPMLGEE

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_009285	XLOC_009285	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00016615	TCONS_00016615	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR006028	GABAA/Glycine_rcpt
IPR006201	Neur_channel
IPR006029	Neurotrans-gated_channel_TM
IPR006202	Neur_chan_lig-bd
IPR018000	Neurotransmitter_ion_chnl_CS

Vocabulary: **Cellular Component**
Term	Definition
GO:0016021	integral component of membrane

Vocabulary: **Biological Process**
Term	Definition
GO:0006811	ion transport

Vocabulary: **Molecular Function**
Term	Definition
GO:0005216	ion channel activity
GO:0005230	extracellular ligand-gated ion channel activity

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0006811	ion transport
cellular_component	GO:0016021	integral component of membrane
molecular_function	GO:0005230	extracellular ligand-gated ion channel activity
molecular_function	GO:0005216	ion channel activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR006028	Gamma-aminobutyric acid A receptor/Glycine receptor alpha	PRINTS	PR00253	GABAARECEPTR	coord: 476..496 score: 48.71 coord: 318..339 score: 39.66 coord: 352..373 score: 40.67 coord: 292..312 score: 51.33
IPR006201	Neurotransmitter-gated ion-channel	PRINTS	PR00252	NRIONCHANNEL	coord: 152..163 score: 48.57 coord: 283..295 score: 29.27 coord: 199..213 score: 50.02 coord: 115..131 score: 26.75
IPR006201	Neurotransmitter-gated ion-channel	TIGRFAM	TIGR00860	TIGR00860	coord: 70..496 e-value: 1.8E-94 score: 315.1
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain	PFAM	PF02932	Neur_chan_memb	coord: 296..453 e-value: 4.4E-26 score: 92.3
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain	SUPERFAMILY	90112	Neurotransmitter-gated ion-channel transmembrane pore	coord: 291..499
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	PFAM	PF02931	Neur_chan_LBD	coord: 71..288 e-value: 1.5E-37 score: 129.1
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	GENE3D	2.70.170.10		coord: 60..295 e-value: 2.6E-46 score: 157.3
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	SUPERFAMILY	63712	Nicotinic receptor ligand binding domain-like	coord: 72..288
None	No IPR available	GENE3D	1.20.58.390		coord: 296..504 e-value: 1.8E-47 score: 160.7
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 441..469
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 38..58
IPR018000	Neurotransmitter-gated ion-channel, conserved site	PROSITE	PS00236	NEUROTR_ION_CHANNEL	coord: 199..213

Blast

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BLAST of TCONS_00016615-protein vs. Swiss-Prot (Human)
Match: GLRA3 (Glycine receptor subunit alpha-3 OS=Homo sapiens GN=GLRA3 PE=1 SV=2)

HSP 1 Score: 226.868 bits (577), Expect = 1.828e-68
Identity = 135/432 (31.25%), Postives = 222/432 (51.39%), Query Frame = 0

Query:   79 NYDKKFKPFFGEKSTNVSLEMHVLSFNRIDESGMEYGIDFYFAQFWNDPRFIDQSKNFHPQQNFINLIGKDVERIWLPDVVFINSKSSRFHDVTINNRFLTIYFDTGRIIYHSRITTTAQCRMDLRDYPFDVQTCYLAIESYGHDERTMKFDWYDQSGQNCESEGCKMIYVYDKEMSNFDVVEAMKSTNKTTYHAERFSSATAKFTFKRRSKYFVLQVYIPCILIVMVTWASFWITPSAAPARTAICVTTILTLITMLGIVNANMPKVSYIKALDLYLFVAFIFVLLSLLEYILVLNLNVNYGGINKYGVKLPFLNHLRRKKKHNPDHHDTNGYSNGRQRLLNGEETSETRFRSNVYKDNTKESTVLEMEKNNNEEKPK--IEEKPKPPAGTSHA------GCDVISRFLFPIGFIVFNVGYWVAYMTQQKE 502
             YD + +P F     NV+  + + SF  I E+ M+Y ++ +  Q WNDPR    + + +P  + ++L    ++ IW PD+ F N K + FH+VT +N+ L I F  G ++Y  R+T T  C MDL+++P DVQTC + +ES+G+    + F+W D++     +EG  +     KE  +      ++   K  Y+  +F+    +F  +R+  Y+++Q+YIP +LIV+++W SFWI   AAPAR A+ +TT+LT+ T      A++PKVSY+KA+D+++ V  +FV  +LLE          Y  +N    +   L   RRK+K+  +      +          +E  E+RF    Y         L+ +     + P   ++  PK P              D ISR  FP+ F++FN+ YWV Y   + E
Sbjct:   56 GYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRL---AYSEYPDDS-LDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRI-FKNGNVLYSIRLTLTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQV-AEGLTLPQFLLKEEKD------LRYCTKH-YNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLE----------YAAVNFVSRQHKELLRFRRKRKNKTEAFALEKFYRFSDM---DDEVRESRFSFTAY----GMGPCLQAKDGMTPKGPNHPVQVMPKSPDEMRKVFIDRAKKIDTISRACFPLAFLIFNIFYWVIYKILRHE 457

The following BLAST results are available for this feature:

BLAST of TCONS_00016615-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00016615-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
GLRA3	1.828e-68	31.25	Glycine receptor subunit alpha-3 OS=Homo sapiens G...	[more]

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TCONS_00016615-protein (polypeptide) - C. hemisphaerica