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Sequence
The following sequences are available for this feature:
polypeptide sequence >TCONS_00015142-protein ID=TCONS_00015142-protein|Name=TCONS_00015142-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1980bp
MGECADGILDTLLQVENLGNAIKTYPIPPIDVLNPERIQIIEDQQEAIAD
LLNKLTLNNNLTCISKVLEDILSIEGTSDDLPHCLYPMLMKKPYLNILYR
EISTTNVELAICVLTKILEYCQDKDDFRQFSRTFFYELDFEFDLQTLLLN
ELEKCLTGEENAETSIVVILLNFLVQFFKRLSHFDLTDQNPVNNMLNFTK
VIIKSIEICMFEEDVALYGIELLECLLLQQRDGMWLMLIKNGWYRVLFDV
LSTHPYEKDVVRSTSCLFTHLFCQSAPAPYEKHLACKSEELLNTKASIGY
FTSESVVYIINRLNFYEDYPDFMYIFLNVIQEISIFEDLAEILIEQGAVS
IIMDWMSQLIGNGKIQLAALKTVQNLKSAGFEDNSDSRWLAEVFAAMIAH
QGNVQVQEAACLTLSSRLASKPELINLIGEGEDHLLPLHGTVLSALNIHA
GNVYVFRAACEAIYQLSIHSSDLQKYLYYKGASASIIREMKNNTNASDVI
GSGCKALRALGLNNPYQHELMFVAEDVLSVIYETLKTFREETVLQECIGL
LVCLATDLPIVLHQCMAMKIPDMILKIADNNFESQRLVEITLEAIALFCS
SEEQQLLHIDCVRSLRRIMEHHVQIASIQIKVCVIMQLINADIHFISNSA
VFQEIVDVLIQAMSSDPDNNILQIEGCIAIYLMFTHKGSKADHVKRYALE
KDVPDILFEIIEDGRQGDKTAILAKDALKMFSSSQHFKDALLQKACLSKR
NKCAEFMIEEQEASLDVRPNLPLCIAVETNNKKLVEMLLNYDSTNASEAL
ALCLDLKNYEIAGVLLRYIGFEQESGYLIWGNLNLKDLRPELIENTLEFQ
VKRKRSSHRGDRSPKSSARPPSRMELDQSPPLSRNNSFTENMNIDEEDSS
SYAHARNIESISGPVLPYNRDDPRLSHNDTIRTQKHFIPFSPRKDFQHHP
QQPNTKPILPEAGHLLPPIDKCPSFGKRSIGQICSSPSDGAINDIIGPVG
SSIFYTPVRNIRSNTSNDLNHPVNKIPKLSSPPVQRRSRHAFSCINQPNV
QPKNNDHIKTLDISHNDLTDIDQLVSYPSLLVKELLSNLQTLHLSENALT
EFSPHCCEALSGLKVLNLAKNKLVDFPYEILHHKNIETIDLSKNLITTLH
SDKVKDTFSLLKLDISHNKLKSFPNWIGASFPRMTKLSFRGNEIREIPDK
SYDFRSIKEINLSHNDINRISPHFFRSCQSLEKIDLSHNRLESLPDFTLS
TLSKLFQVKLSHNCLKGQKPFYIPKALLAIPSLTMVDLSYNSIMQMPDPS
FWSAKGLKELNLANNRIQQINLSTNSKDFWPEISRLNLSNNNIRNLPAEI
GFLDSLVSFDVSHNQINELPNEIGLLKKVFELNLKENPLKHDPALQNFRP
QDIIGHHRYKLKNAVPYRRMKLMLVGYGGRGKSSLLRQLVNMKHPTHNVA
TVGVELRDWELKPPSRFFEKSRPTFTLNTWDFAGQEEFYSTHQYFLSSRA
LYLAVFDASQTGTSELDNLRPWLLNIQASAPAAMVILVGTHIDQIPREVR
EEHVNLLLGYMNKFVCEPGLPKIEAKFVVNCMRETSAMEKLREKIYSIVS
NFKYEGQQIIEQMVPNAYVLLEKLLCEEVAKMHAEKLLPIRKWDQIVKMC
QDGKLVIDDEELKCALKFLKETGSIMHFSDASGTINNLYFIDPQWLCQMM
ARVVTIREINPWIDEHGVLPKEKSSQLFPNDKFPLEFLDRYFKLLQMFEI
VLPLSDKDYLVTARVPQSPPDYIPKHQKNCVTDENVVTRRYRLPYFPSGF
WTRLITRILVYQKENLSSEPNIIDYWQTGMYMSWDVNSLFLITTVPEKQN
IFDIYVPMNQHGFMVLGVVVDLVDNLIEEWYPGLSDSSYSSRSSIQRLVP
CNTCRGDLYGNCHYFTVAQCTKESHHSDIIECPQCGPRRIRDVAPDVVFA
DIDQSLIVERINIDENGLRAXRSGRCFRGH Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
This polypeptide derives from the following transcript feature(s):
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: Biological Process
| Term | Definition |
|---|
| GO:0007264 | small GTPase mediated signal transduction |
Vocabulary: Molecular Function
| Term | Definition |
|---|
| GO:0005525 | GTP binding |
| GO:0005515 | protein binding |
| GO:0005488 | binding |
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
| Category |
Term Accession |
Term Name |
| biological_process |
GO:0007264 |
small GTPase mediated signal transduction |
| molecular_function |
GO:0005488 |
binding |
| molecular_function |
GO:0005525 |
GTP binding |
| molecular_function |
GO:0005515 |
protein binding |
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
| IPR Term | IPR Description | Source | Source Term | Source Description | Alignment |
|---|
| None | No IPR available | PRINTS | PR00449 | RASTRNSFRMNG | coord: 1468..1490
score: 34.98
coord: 1420..1441
score: 41.39
coord: 1531..1544
score: 31.27 |
| None | No IPR available | SMART | SM00364 | LRR_bac_2 | coord: 1086..1105
e-value: 210.0
score: 3.6
coord: 1055..1074
e-value: 360.0
score: 1.8
coord: 1353..1372
e-value: 290.0
score: 2.5
coord: 1331..1349
e-value: 110.0
score: 5.8
coord: 1228..1247
e-value: 0.59
score: 19.2
coord: 1159..1176
e-value: 140.0
score: 5.0 |
| None | No IPR available | SMART | SM00365 | LRR_sd22_2 | coord: 1353..1384
e-value: 290.0
score: 3.6
coord: 1304..1324
e-value: 140.0
score: 6.1
coord: 1055..1076
e-value: 360.0
score: 2.8
coord: 1133..1154
e-value: 96.0
score: 7.5
coord: 1228..1249
e-value: 170.0
score: 5.5
coord: 1086..1112
e-value: 470.0
score: 1.9 |
| None | No IPR available | SMART | SM00175 | rab_sub_5 | coord: 1420..1598
e-value: 7.7E-6
score: -36.8 |
| None | No IPR available | GENE3D | 3.30.70.1390 | | coord: 1418..1498
e-value: 4.5E-16
score: 58.1 |
| None | No IPR available | GENE3D | 3.40.50.300 | | coord: 1499..1636
e-value: 3.7E-4
score: 20.0 |
| IPR003591 | Leucine-rich repeat, typical subtype | SMART | SM00369 | LRR_typ_2 | coord: 1280..1303
e-value: 32.0
score: 9.1
coord: 1305..1327
e-value: 300.0
score: 1.2
coord: 1330..1351
e-value: 180.0
score: 2.9
coord: 1086..1109
e-value: 0.083
score: 22.0
coord: 1204..1227
e-value: 18.0
score: 11.1
coord: 1353..1376
e-value: 1.5
score: 17.9
coord: 1228..1251
e-value: 12.0
score: 12.5
coord: 1110..1133
e-value: 7.2
score: 14.4
coord: 1181..1203
e-value: 330.0
score: 0.8
coord: 1159..1180
e-value: 120.0
score: 4.5 |
| IPR032675 | Leucine-rich repeat domain, L domain-like | GENE3D | 3.80.10.10 | | coord: 1024..1162
e-value: 1.7E-17
score: 62.8 |
| IPR032675 | Leucine-rich repeat domain, L domain-like | GENE3D | 3.80.10.10 | | coord: 1163..1283
e-value: 1.0E-27
score: 96.0 |
| IPR032675 | Leucine-rich repeat domain, L domain-like | GENE3D | 3.80.10.10 | | coord: 1284..1400
e-value: 2.9E-20
score: 71.7 |
| IPR032675 | Leucine-rich repeat domain, L domain-like | SUPERFAMILY | 52058 | L domain-like | coord: 1049..1400 |
| IPR011989 | Armadillo-like helical | GENE3D | 1.25.10.10 | | coord: 212..639
e-value: 1.3E-18
score: 66.3 |
| IPR013684 | Mitochondrial Rho-like | PFAM | PF08477 | Roc | coord: 1421..1544
e-value: 1.2E-27
score: 96.5 |
| IPR032171 | C-terminal of Roc (COR) domain | PFAM | PF16095 | COR | coord: 1615..1831
e-value: 1.1E-23
score: 84.0 |
| IPR001611 | Leucine-rich repeat | PFAM | PF13855 | LRR_8 | coord: 1057..1123
e-value: 1.2E-7
score: 31.2
coord: 1182..1241
e-value: 5.7E-10
score: 38.7 |
| IPR001611 | Leucine-rich repeat | PROSITE | PS51450 | LRR | coord: 1088..1109
score: 6.765 |
| IPR001611 | Leucine-rich repeat | PROSITE | PS51450 | LRR | coord: 1282..1303
score: 6.357 |
| IPR001611 | Leucine-rich repeat | PROSITE | PS51450 | LRR | coord: 1378..1399
score: 4.909 |
| IPR001611 | Leucine-rich repeat | PROSITE | PS51450 | LRR | coord: 1306..1327
score: 7.566 |
| IPR001611 | Leucine-rich repeat | PROSITE | PS51450 | LRR | coord: 1230..1251
score: 8.628 |
| IPR001611 | Leucine-rich repeat | PROSITE | PS51450 | LRR | coord: 1112..1133
score: 6.118 |
| IPR001611 | Leucine-rich repeat | PROSITE | PS51450 | LRR | coord: 1057..1078
score: 7.981 |
| IPR001611 | Leucine-rich repeat | PROSITE | PS51450 | LRR | coord: 1159..1180
score: 7.134 |
| IPR001611 | Leucine-rich repeat | PROSITE | PS51450 | LRR | coord: 1135..1156
score: 5.764 |
| IPR001611 | Leucine-rich repeat | PROSITE | PS51450 | LRR | coord: 1183..1204
score: 5.071 |
| IPR001611 | Leucine-rich repeat | PROSITE | PS51450 | LRR | coord: 1332..1353
score: 7.08 |
| IPR001611 | Leucine-rich repeat | PROSITE | PS51450 | LRR | coord: 1355..1376
score: 7.62 |
| IPR001611 | Leucine-rich repeat | PROSITE | PS51450 | LRR | coord: 1206..1227
score: 6.541 |
| IPR020683 | Ankyrin repeat-containing domain | GENE3D | 1.25.40.20 | | coord: 698..868
e-value: 7.2E-6
score: 24.9 |
| IPR020683 | Ankyrin repeat-containing domain | SUPERFAMILY | 48403 | Ankyrin repeat | coord: 729..818 |
| IPR020859 | Roc domain | PROSITE | PS51424 | ROC | coord: 1413..1602
score: 39.765 |
| IPR027417 | P-loop containing nucleoside triphosphate hydrolase | SUPERFAMILY | 52540 | P-loop containing nucleoside triphosphate hydrolases | coord: 1418..1615 |
| IPR016024 | Armadillo-type fold | SUPERFAMILY | 48371 | ARM repeat | coord: 212..477
coord: 82..124 |
| IPR016024 | Armadillo-type fold | SUPERFAMILY | 48371 | ARM repeat | coord: 434..734 |
Blast
BLAST of TCONS_00015142-protein vs. Swiss-Prot (Human)
Match: LRRK2 (Leucine-rich repeat serine/threonine-protein kinase 2 OS=Homo sapiens GN=LRRK2 PE=1 SV=2) HSP 1 Score: 497.278 bits (1279), Expect = 1.697e-143 Identity = 311/922 (33.73%), Postives = 519/922 (56.29%), Query Frame = 0
Query: 1056 DHIKTLDISHNDLTDIDQLVSYPSLLVKELLSNLQTLHLSENALTEFSPHCCEALSGLKVLNLAKNKLVDFPYEILHHKNIETIDLSKNLIT-TLHSDKVKDTFSLLKLDISHNKLKSFPNWIGASFPRMTKLSFRGNEIREIPDKSYDFRSIKEINLSHNDINRISPHFFRSCQSLEKIDLSHNRLESLPDFTLS-TLSKLFQVKLSHNCLKGQKPFYIPKALLAIPSLTMVDLSYNSIMQMPDPSFWSAKGLKELNLANNRIQQINLSTNSKDFWPEISRLNLSNNNIRNLPAEIGFLDSLVSFDVSHN-QINELPNEIGLLKKVFELNLKENPLKHDPALQNFRPQDIIGHHRYKLKNAVPYRRMKLMLVGYGGRGKSSLLRQLVNMKHPTHNV--ATVGVELRDWELKPPSRFFEKSRPTFTLNTWDFAGQEEFYSTHQYFLSSRALYLAVFDASQTGTSELDNLRPWLLNIQASAPAAMVILVGTHIDQIPREVREEHVNLLLGYMNKFVCEPGLPKIEAKFVVNCMRETSAMEKLREKIYSIVSNFKYEGQQIIEQMVPNAYVLLEKLLCEEVAKMHAEKLLPIRKWDQIVKMCQDGKLVIDDEELKCALKFLKETGSIMHFSDASGTINNLYFIDPQWLCQMMARVVTIREINPWIDEHGVLPKEKSSQLFPND-KFPLEFLDRYFKLLQMFEIVLPLSDKDYLVTARVPQSPPDYIPKHQKNCVTDENVVTRRYRLPYFPSGFWTRLITRILVYQKENLSS-----EPNIIDYWQTGMYMSWDVNSLFLITTVP---EKQNIFDIYVPMNQHGFMVLGVVVDLVDNLIEEWYPGL--SDSSYSSRSSIQRLVPCNTCRGDLYGNCHYFTVAQCTKESHHSDIIECPQCGPRR---IRDVAPDVVFADIDQSLIV 1958
++I +LD+S N+L DID L + V L +L+ L L +NALT F CE L L L+L NK FP +L I +D+S+N I ++ D +L + ++S+N+L P + ++ +L GN+I I + +K +NLS N I+ +S +F +C +E N L ++P S T+ KL Q K S C IP+A+L +P L +D+S N I +P P+ W + L+EL ++N+I ++LS + W + +L+LS+N ++ +P EIG L++L S DVS+N ++ PNE+G L K+++L L E L D + +DII + +LK AVPY RMKLM+VG G GK++LL+QL+ K + ATVG++++DW P + +K + LN WDFAG+EEFYSTH +F++ RALYLAV+D S+ G +E+D ++PWL NI+A A ++ VILVGTH+D + R+ ++ + + + + G P I VN E+ A+ KLR+ I + NFK Q ++ Q++P+ YV LEK++ E + E P+ +++++ ++ +L +D+ EL A+ FL E+G ++HF D + +++LYF++P+WLC++MA+++T++ G++ + + KFP ++ +YFKLL+ F+I LP+ + +YL+ VP S D+ P + + ++ R Y +PYFP GFW+RLI R+L LS PN + YW+ G+Y++W + L+ + ++ I VP + G ++LG VVD +D+L+EEW+PGL D + +++ + G+ + + K++ D++ P PR I +APD++ AD+ +++++
Sbjct: 982 EYITSLDLSANELRDIDALSQKCCISVH--LEHLEKLELHQNALTSFPQQLCETLKSLTHLDLHSNKFTSFPSYLLKMSCIANLDVSRNDIGPSVVLDPTVKCPTLKQFNLSYNQLSFVPENLTDVVEKLEQLILEGNKISGICS-PLRLKELKILNLSKNHISSLSENFLEACPKVESFSARMNFLAAMPFLPPSMTILKLSQNKFS--C--------IPEAILNLPHLRSLDMSSNDIQYLPGPAHWKSLNLRELLFSHNQISILDLSEKAY-LWSRVEKLHLSHNKLKEIPPEIGCLENLTSLDVSYNLELRSFPNEMGKLSKIWDLPLDELHLNFDFKHIGCKAKDIIRFLQQRLKKAVPYNRMKLMIVGNTGSGKTTLLQQLMKTKKSDLGMQSATVGIDVKDW----PIQIRDKRKRDLVLNVWDFAGREEFYSTHPHFMTQRALYLAVYDLSK-GQAEVDAMKPWLFNIKARASSSPVILVGTHLDVSDEKQRKACMSKI---TKELLNKRGFPAIRDYHFVNATEESDALAKLRKTIINESLNFKIRDQLVVGQLIPDCYVELEKIILSERKNVPIE--FPVIDRKRLLQLVRENQLQLDENELPHAVHFLNESGVLLHFQDPALQLSDLYFVEPKWLCKIMAQILTVKVEGCPKHPKGIISRRDVEKFLSKKRKFPKNYMSQYFKLLEKFQIALPIGE-EYLL---VPSSLSDHRPVIELPHCENSEIIIRLYEMPYFPMGFWSRLINRLLEISPYMLSGRERALRPNRM-YWRQGIYLNWSPEAYCLVGSEVLDNHPESFLKITVPSCRKGCILLGQVVDHIDSLMEEWFPGLLEIDICGEGETLLKKWALYSFNDGEEH---QKILLDDLMKKAEEGDLLVNPD-QPRLTIPISQIAPDLILADLPRNIML 1870
The following BLAST results are available for this feature:
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