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Sequence
The following sequences are available for this feature:
polypeptide sequence >TCONS_00015037-protein ID=TCONS_00015037-protein|Name=TCONS_00015037-protein|organism=Clytia hemisphaerica|type=polypeptide|length=2036bp
KIQLDKFGRLVMEFNVFLLVLCIKVLPVPATHDYEIVRPEMLDHQHNRMR
RSIYTKLPDEDKHVDKLTLKIPTQQKDFVLDLKKKRTFSDGGITVRTFDE
NGKSQHKTTVPEDCHYIGVVKDHPNSHAHISTCHGVTGTIQDGEETYDIL
PHDNEKGDHKFIKAADIIKKASHQVNKDHEIFHPEDQRFDSEDAPALDEH
PDKIITTHKVTKDNTVHLANTENVYMPYLKSNVTKFVEIFVSIDRQIFEY
YGRDEKLVIEKALHTVSQLDMSYQAINIRLVLVAIEIQKEGPHFTRSLWA
HEELGAFSKYYKDVIMKDLSFLSIDNAVFLSHRSWHNGVIGLAFVGATCS
SLATSIVGWSFYDISGPVFVLGHEIGHTLNFPHDGDTCRCLSERGCFMKG
SKSSKPGFSDCSLKYFAKKDYACLSNYPKSTVVAVCGNGIIEGNEECDCG
TPEMCSKIDPCCQPHHCRLKAHAQCSYQNSPTCCSQKCLFKKQGELCRSS
ESNCDLPEFCTGDSAKCPKDEVMRDGSSCGDSKKLIAGTEERYKGHLSQL
SPRVYGRYFKFIPKYWGKKDYPCMAIEMFGCGKDDDQFVTPTPITTKALY
YHSPMCIKLKAIDTCQHVADGTLLIYKTTEHHDCNHEHMLFVHGVDGTLT
HHCSQKRVCPNDKGQLVVSSQCELEVSKFTRTKKKSLKHVQSNKCALSED
HWPHSNDIMALRGICDEVETKRTELIFLNTDCVLPMNFTNGKLPDTAFTS
KTHMGIHSAHEARYSRRTWCGESKKDETWLQVDLGKEVKVSSIIVKGCYF
GFVMSYYLMFSNDGVHWDAYKESHATSWKDMNSFCYRGNCIKTYDHQCQQ
LWSAASKKAKEPCWKEMNVKNETFGTCDPFKHEYCKERDMYCGQIQCESK
YQVPYYVNYGSSYTTQMINSSKCSAASIMKSEQSGFGMVSDGTKCGQGKM
CMNQKCLTSEEHGIKHCPFINGTECNGKGICRSDGKCFCHGGYDPSTGCK
TPLIPVNGGWSAWSSWGLCNKACGSGQHIRHRYCNQPIAKHGGKQCEGDW
KEYEGCNKEPCPAARSCKQMKSQLESKGKHAFDGIYLIQPSDGIKIKAYC
DMTRHGGGWTLLITSLNNRWTPENVLERNIKEPSLSKDYSILKYGDAIKK
SSYMMKPHFEYMLEAHNPDEWGGIWRADGDYSLKSTDRYQSNVRLLKKFS
DWSYSNKGIVQRVPYLYHQRLTMSEKPDKVFWGTITDNRTDVVPASWIQG
KQKMEAPNKIWYWVRESDVDIPGSCLEIMLRGMNFKTPYKSGVYNIQPKR
DQTVKTYCDFERHGGGWALLAVSKRGSRWTKDESLANGTDPLGDKFSLFG
LVDHLKQRDPAEIEFEYIIEAEDSKGNKHGGIFTSSTKYSLLTCPPHGST
PKLIQKIGVWNETEENIAKYPVYFANKDNKIFITASSDKPSDTLGTIISD
NNNGVFMKSLPSAEVVKVWIREGGSRKSCNDIKVHGYHKGKLDYEDGYYR
IENSQIVYCDMTTTPNEGWTLVLTSKTSGWNMDQVKSRNANRPSLHDDYS
ILNQAEKIKKLSQSDFFKYMLDATARADWGGIWRAPINYPLASTSSARYE
VTMVEQFGQWDYEKRWYQNPRQRMPYMASGNREKALLTTATYTYYTEWGS
IVANDSQGYVPAKWITPQKESPGVIWYWINENDCEDDYKPVHGGFEPWSE
WSQCSVFCGVGKQVRRRLCNTPLPKCGGDPCDPKEKRLQERECQGECSTS
IIRTKSDEYCVVPKTNGCDEITTKTDLILSSSRCDQPEAKFIYNPSNGEL
RHQCSQQLVCEKDWTVGIDVNCQHGSSGAQFSRMFDFLRASNKRCIGLSN
GETEDSKIKVHSSCKDILRFPEIANGPVNSDFFLNMPTNIKNIAQIKALP
KYPAFPSFSTHLDNFDAPHDIGSYYALKTWTYFKAPETGEYRFSVSCDDF
CSLFLGENQESTEEIVTFTSWVPLYVWNRHPSQTSHPINLIAGQKYYMEM
IAGEIKGADHFTVAVKFPDGKFVGPITTNYLHSNSE Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
This polypeptide derives from the following transcript feature(s):
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: Molecular Function
| Term | Definition |
|---|
| GO:0008237 | metallopeptidase activity |
| GO:0004222 | metalloendopeptidase activity |
Vocabulary: Biological Process
| Term | Definition |
|---|
| GO:0006508 | proteolysis |
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
| Category |
Term Accession |
Term Name |
| biological_process |
GO:0006508 |
proteolysis |
| molecular_function |
GO:0004222 |
metalloendopeptidase activity |
| molecular_function |
GO:0008237 |
metallopeptidase activity |
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
| IPR Term | IPR Description | Source | Source Term | Source Description | Alignment |
|---|
| IPR001762 | Disintegrin domain | SMART | SM00050 | DISIN_2 | coord: 442..523
e-value: 2.0E-26
score: 103.8 |
| IPR001762 | Disintegrin domain | PFAM | PF00200 | Disintegrin | coord: 442..520
e-value: 4.0E-18
score: 65.9 |
| IPR001762 | Disintegrin domain | GENE3D | 4.10.70.10 | | coord: 440..513
e-value: 8.2E-20
score: 70.8 |
| IPR001762 | Disintegrin domain | PROSITE | PS50214 | DISINTEGRIN_2 | coord: 433..525
score: 17.182 |
| IPR001762 | Disintegrin domain | SUPERFAMILY | 57552 | Blood coagulation inhibitor (disintegrin) | coord: 442..521 |
| IPR006586 | ADAM, cysteine-rich | SMART | SM00608 | acr | coord: 831..959
e-value: 4.4E-13
score: 59.5 |
| IPR006586 | ADAM, cysteine-rich | PFAM | PF08516 | ADAM_CR | coord: 830..930
e-value: 4.7E-17
score: 62.4 |
| IPR000884 | Thrombospondin type-1 (TSP1) repeat | SMART | SM00209 | TSP1_2 | coord: 1695..1748
e-value: 4.4E-10
score: 49.5
coord: 1010..1062
e-value: 4.3E-13
score: 59.5 |
| IPR000884 | Thrombospondin type-1 (TSP1) repeat | GENE3D | 2.20.100.10 | | coord: 1006..1061
e-value: 1.7E-13
score: 50.1
coord: 1691..1747
e-value: 2.1E-11
score: 43.5 |
| IPR000884 | Thrombospondin type-1 (TSP1) repeat | PFAM | PF00090 | TSP_1 | coord: 1697..1739
e-value: 8.4E-9
score: 35.4
coord: 1011..1061
e-value: 3.4E-11
score: 43.1 |
| IPR000884 | Thrombospondin type-1 (TSP1) repeat | PROSITE | PS50092 | TSP1 | coord: 1692..1748
score: 12.225 |
| IPR000884 | Thrombospondin type-1 (TSP1) repeat | PROSITE | PS50092 | TSP1 | coord: 1007..1062
score: 13.071 |
| IPR000884 | Thrombospondin type-1 (TSP1) repeat | SUPERFAMILY | 82895 | TSP-1 type 1 repeat | coord: 1004..1061 |
| IPR000884 | Thrombospondin type-1 (TSP1) repeat | SUPERFAMILY | 82895 | TSP-1 type 1 repeat | coord: 1690..1744 |
| IPR014716 | Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1 | GENE3D | 3.90.215.10 | | coord: 1471..1620
e-value: 3.4E-4
score: 20.0 |
| IPR014716 | Fibrinogen, alpha/beta/gamma chain, C-terminal globular, subdomain 1 | GENE3D | 3.90.215.10 | | coord: 1062..1241
e-value: 2.1E-8
score: 33.7
coord: 1268..1373
e-value: 7.8E-8
score: 31.9 |
| IPR002870 | Peptidase M12B, propeptide | PFAM | PF01562 | Pep_M12B_propep | coord: 35..157
e-value: 9.0E-22
score: 77.7 |
| IPR024079 | Metallopeptidase, catalytic domain | GENE3D | 3.40.390.10 | | coord: 230..428
e-value: 2.4E-35
score: 121.8 |
| IPR008979 | Galactose-binding domain-like | GENE3D | 2.60.120.260 | | coord: 715..933
e-value: 2.9E-15
score: 55.9 |
| IPR008979 | Galactose-binding domain-like | GENE3D | 2.60.120.260 | | coord: 514..583
e-value: 0.014
score: 14.9 |
| IPR008979 | Galactose-binding domain-like | SUPERFAMILY | 49785 | Galactose-binding domain-like | coord: 731..827 |
| IPR001590 | Peptidase M12B, ADAM/reprolysin | PFAM | PF01421 | Reprolysin | coord: 235..428
e-value: 3.1E-28
score: 99.0 |
| IPR001590 | Peptidase M12B, ADAM/reprolysin | PROSITE | PS50215 | ADAM_MEPRO | coord: 235..418
score: 26.504 |
| IPR018871 | GLEYA adhesin domain | PFAM | PF10528 | GLEYA | coord: 1926..2015
e-value: 2.3E-6
score: 27.9 |
| IPR000421 | Coagulation factor 5/8 C-terminal domain | PFAM | PF00754 | F5_F8_type_C | coord: 760..823
e-value: 8.4E-10
score: 38.8 |
| IPR000421 | Coagulation factor 5/8 C-terminal domain | PROSITE | PS50022 | FA58C_3 | coord: 732..823
score: 16.312 |
| None | No IPR available | GENE3D | 2.60.120.380 | | coord: 1874..2016
e-value: 2.3E-15
score: 56.5 |
| None | No IPR available | SUPERFAMILY | 56988 | Anthrax protective antigen | coord: 1932..1999 |
| None | No IPR available | SUPERFAMILY | 55486 | Metalloproteases ("zincins"), catalytic domain | coord: 234..428 |
| IPR002181 | Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain | SUPERFAMILY | 56496 | Fibrinogen C-terminal domain-like | coord: 1061..1119 |
| IPR002181 | Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain | SUPERFAMILY | 56496 | Fibrinogen C-terminal domain-like | coord: 1269..1323 |
Blast
BLAST of TCONS_00015037-protein vs. Swiss-Prot (Human)
Match: ADAM9 (Disintegrin and metalloproteinase domain-containing protein 9 OS=Homo sapiens GN=ADAM9 PE=1 SV=1) HSP 1 Score: 199.904 bits (507), Expect = 2.274e-52 Identity = 149/542 (27.49%), Postives = 243/542 (44.83%), Query Frame = 0
Query: 34 YEIVRPEMLDHQHNRMRRSIYTKLPDEDKHVDKLTLKIPTQQKDFVLDLKKKRTFSDGGITVRTFDENGK--SQHKTTVPEDCHYIGVVKDHPNSHAHISTCHGVTGTIQDGEETYDILPHDNEKGDHKFIKAADIIKKASHQVNKDHEIFHPEDQRFDSEDAPALDEHPDKIITTHKVTKDNTVHLANTENVYMPYLKSNVTKFVEIFVSIDRQIFEYYGRDEKLVIEKALHTVSQLDMSYQAINIRLVLVAIEIQKEGPHFTRSLWAHEELGAFSKYYKDVIMKDLSFLSIDNAVFLSHRSWHNGVIGLAFVGATCS-SLATSIVGWSFYDISGPVFVLGHEIGHTLNFPHD-GDTCRCLSERGCFMKGSKSSKPGFSDCSLKYFAK----KDYACLSNYPK---STVVAVCGNGIIEGNEECDCGTPEMCSKIDPCCQPHHCRLKAHAQCSYQNSPTCCSQKCLFKKQGELCRSSESNCDLPEFCTGDSAKCPKDEVMRDGSSCGDSKKLIAGTEERYKGHLSQLSPRVYGRYFKFIPK 564
YEI+ P L + R Y+K +++ I + K+ ++ L++ + V T+++ G + H + CHY G V+ NS +S C G+ G + +Y I P N I D + K + ++ E + + E+ P++ + L +P T++VE+F+ +D++ ++ GR++ V E+ + + LD Y +NIR+VLV +EI G A + LG F ++ + ++ D+A + + + G G+AFVG CS S A I + + ++ HE+GH L HD G C C + C M S FS CS + F K K CL N PK + CGN +++ EECDCGTP+ C ++DPCC+ C+LK+ A+C+Y + C + C F G LCR S CD+PE+C G S C D +++G C ++K +Y Q+ ++G K PK
Sbjct: 43 YEIITPWRLTRERREAPRP-YSK---------QVSYVIQAEGKEHIIHLERNKDLLPEDFVVYTYNKEGTLITDHPN-IQNHCHYRGYVEGVHNSSIALSDCFGLRGLLHLENASYGIEPLQNSSHFEHIIYRMDDVYKEPLKCGVSNKDIEKETAKDEEEEPPSMTQ------------------LLRRRRAVLPQ-----TRYVELFIVVDKERYDMMGRNQTAVREEMILLANYLDSMYIMLNIRIVLVGLEIWTNGNLINIVGGAGDVLGNFVQWREKFLITRRRH---DSAQLVLKKGF-GGTAGMAFVGTVCSRSHAGGINVFGQITVETFASIVAHELGHNLGMNHDDGRDCSC-GAKSCIMNSGASGSRNFSSCSAEDFEKLTLNKGGNCLLNIPKPDEAYSAPSCGNKLVDAGEECDCGTPKEC-ELDPCCEGSTCKLKSFAECAYGD----CCKDCRFLPGGTLCRGKTSECDVPEYCNGSSQFCQPDVFIQNGYPCQNNKAYCYNGMCQYYDAQCQV---IFGSKAKAAPK 537 HSP 2 Score: 88.9669 bits (219), Expect = 1.652e-17 Identity = 55/172 (31.98%), Postives = 92/172 (53.49%), Query Frame = 0
Query: 833 SFCYRGNCIKTYDHQCQQLWSAASKKAKEPCWKEMNVKNETFGTCDPFKHEY--CKERDMYCGQIQCESKYQVPYYVNYGSSYTTQMINSSKCSAASI-MKSEQSGFGMVSDGTKCGQGKMCMNQKCLTSEEHGIKHCPFINGTECNGKGICRSDGKCFCHGGYDPSTGCKT 1001
++CY G C + YD QCQ ++ + +K A + C+ E+N K + FG C +EY C + CG++QCE+ ++P + + T +KC + S+ GMV++GTKCG GK+C N +C+ + + + +C+G G+C S+ C C G+ P C+T
Sbjct: 510 AYCYNGMC-QYYDAQCQVIFGSKAKAAPKDCFIEVNSKGDRFGNCGFSGNEYKKCATGNALCGKLQCENVQEIPVFGIVPAIIQTPS-RGTKCWGVDFQLGSDVPDPGMVNEGTKCGAGKICRNFQCVDAS---VLNYDCDVQKKCHGHGVCNSNKNCHCENGWAPPN-CET 675
The following BLAST results are available for this feature:
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