TCONS_00015022-protein (polypeptide) - C. hemisphaerica

BLAST of TCONS_00015022-protein vs. Swiss-Prot (Human)
Match: MDR1 (Multidrug resistance protein 1 OS=Homo sapiens GN=ABCB1 PE=1 SV=3)

HSP 1 Score: 803.897 bits (2075), Expect = 0.000e+0
Identity = 417/947 (44.03%), Postives = 613/947 (64.73%), Query Frame = 0

Query:  111 EAEKAGGRGKRK--KFDN-----------SVTLRQLFQFSDKLDVLYMVFGSLGAIFHGLSLPGQLIIFGQLVNNFIDFTQQRELIRKNATAVAPEDV---IDIESEMLFYAQIYAYVAVASWIVGYMQCAFWSISAIRQIQRIRMLFFNSILRQDVGWFDVNEAGGLTTRMFEDLQQIQSGIGDKVGNTLQAVSTLVGGFGVAFVFGWKLALVMLAVCPLIVMAGALTGKVMASLTSKEQTAYAQAGAIAEQAISSIRTVVAFGGEKEELDSYNAKLVLAEEAGIKKAITGAFSMGVFFIVMAGAEALAFWYGSTLVADEDFPPGSLLTVFFSILIGSAQIGQAGPNMEALATAKGAAYYVYQVIKRKSPIDTMNEEGKKPDFYSADQIQFQNIHFHYPSRTDIPVLQGFDLTVNKGQTVALVGESGCGKSTTIKLLQRFYDVIGGSVIIGKDNIKDINVKWLRQHIGIVSQEPVLFDMTIADNIRMGKDNATQQEIEQAAINANAHDFITNLPKGYDTNVGEGGAQLSGGQKQRIAIARALIKDPQILLLDEATSALDTESESIVQTALDNASMGRTTIIIAHRLSTVKNADLIVAVQDGRVAEKGTHDELMARKGVYYQLVMLQTLAEQEEHELSETGSLITEEEREALLQVRMMRSLSQMSGEQGASIEDISFARALSVRKSKSDRKKRTKKVKKKSKKEALIEEAVDPAPISRVLSYNKPEWHLMGMGLIFSAMHGCIPIFFAFIIGQVLGALA-LPDKEQIKEESKKWSLVFLAMGAANCIGYGMGNYLFGKSGERLTRRLRSKAFECILKQDIAYFDDPYHGTGQLTARLATDASKVKGATSSRISVLVQVSFTALSALFVAFYYSWKLTLLVIAFVPFLVFGGVMRASRFKNFAAKEGKRLLEASAVSQQALMNIRTVASLGKEDYFYERFSCLLQEPY 1040
            E ++ GG  K+   K +N           +V++  +F++S+ LD LYMV G+L AI HG  LP  +++FG++ + F +     +L+          D    +++E +M  YA  Y+ +     +  Y+Q +FW ++A RQI +IR  FF++I+RQ++GWFDV++ G L TR+ +D+ +I  GIGDK+G   Q+++T   GF V F  GWKL LV+LA+ P++ ++ A+  K+++S T KE  AYA+AGA+AE+ +++IRTV+AFGG+K+EL+ YN  L  A+  GIKKAIT   S+G  F+++  + ALAFWYG+TLV   ++  G +LTVFFS+LIG+  +GQA P++EA A A+GAAY ++++I  K  ID+ ++ G KPD    + ++F+N+HF YPSR ++ +L+G +L V  GQTVALVG SGCGKSTT++L+QR YD   G V +   +I+ INV++LR+ IG+VSQEPVLF  TIA+NIR G++N T  EIE+A   ANA+DFI  LP  +DT VGE GAQLSGGQKQRIAIARAL+++P+ILLLDEATSALDTESE++VQ ALD A  GRTTI+IAHRLSTV+NAD+I    DG + EKG HDELM  KG+Y++LV +QT   + E E +   S   + E +AL          +MS     S    S  R  S R+S    + + +K+   S KEAL +E++ P    R++  N  EW    +G+  + ++G +   FA I  +++G    + D E  ++ S  +SL+FLA+G  + I + +  + FGK+GE LT+RLR   F  +L+QD+++FDDP + TG LT RLA DA++VKGA  SR++V+ Q      + + ++F Y W+LTLL++A VP +   GV+        A K+ K L  +  ++ +A+ N RTV SL +E  F   ++  LQ PY
Sbjct:    4 EGDRNGGAKKKNFFKLNNKSEKDKKEKKPTVSVFSMFRYSNWLDKLYMVVGTLAAIIHGAGLPLMMLVFGEMTDIFANAGNLEDLMSNITNRSDINDTGFFMNLEEDMTRYAYYYSGIGAGVLVAAYIQVSFWCLAAGRQIHKIRKQFFHAIMRQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGMFFQSMATFFTGFIVGFTRGWKLTLVILAISPVLGLSAAVWAKILSSFTDKELLAYAKAGAVAEEVLAAIRTVIAFGGQKKELERYNKNLEEAKRIGIKKAITANISIGAAFLLIYASYALAFWYGTTLVLSGEYSIGQVLTVFFSVLIGAFSVGQASPSIEAFANARGAAYEIFKIIDNKPSIDSYSKSGHKPDNIKGN-LEFRNVHFSYPSRKEVKILKGLNLKVQSGQTVALVGNSGCGKSTTVQLMQRLYDPTEGMVSVDGQDIRTINVRFLREIIGVVSQEPVLFATTIAENIRYGRENVTMDEIEKAVKEANAYDFIMKLPHKFDTLVGERGAQLSGGQKQRIAIARALVRNPKILLLDEATSALDTESEAVVQVALDKARKGRTTIVIAHRLSTVRNADVIAGFDDGVIVEKGNHDELMKEKGIYFKLVTMQTAGNEVELENAADES---KSEIDAL----------EMSSNDSRS----SLIRKRSTRRSVRGSQAQDRKL---STKEAL-DESIPPVSFWRIMKLNLTEWPYFVVGVFCAIINGGLQPAFAIIFSKIIGVFTRIDDPETKRQNSNLFSLLFLALGIISFITFFLQGFTFGKAGEILTKRLRYMVFRSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGAIGSRLAVITQNIANLGTGIIISFIYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELEGSGKIATEAIENFRTVVSLTQEQKFEHMYAQSLQVPY 928          

HSP 2 Score: 444.121 bits (1141), Expect = 8.094e-137
Identity = 243/586 (41.47%), Postives = 357/586 (60.92%), Query Frame = 0

Query:  144 YMVFGSLGAIFHGLSLPGQLIIFGQLVNNFIDFTQQRELIRKNATAVAPEDVIDIESEMLFYAQIYAYVAVASWIVGYMQCAFWSISAIRQIQRIRMLFFNSILRQDVGWFD--VNEAGGLTTRMFEDLQQIQSGIGDKVGNTLQAVSTLVGGFGVAFVFGWKLALVMLAVCPLIVMAGALTGKVMASLTSKEQTAYAQAGAIAEQAISSIRTVVAFGGEKEELDSYNAKLVLAEEAGIKKA----ITGAFSMGVFFIVMAGAEALAFWYGSTLVADEDFPPGSLLTVFFSILIGSAQIGQAGPNMEALATAKGAAYYVYQVIKRKSPIDTMNEEGKKPDFYSADQIQFQNIHFHYPSRTDIPVLQGFDLTVNKGQTVALVGESGCGKSTTIKLLQRFYDVIGGSVIIGKDNIKDINVKWLRQHIGIVSQEPVLFDMTIADNIRMGKDN--ATQQEIEQAAINANAHDFITNLPKGYDTNVGEGGAQLSGGQKQRIAIARALIKDPQILLLDEATSALDTESESIVQTALDNASMGRTTIIIAHRLSTVKNADLIVAVQDGRVAEKGTHDELMARKGVYYQLVMLQ 721
            Y V G   AI +G   P   IIF +++  F       E  R+N+                 ++ ++  + + S+I  ++Q   +  +     +R+R + F S+LRQDV WFD   N  G LTTR+  D  Q++  IG ++    Q ++ L  G  ++F++GW+L L++LA+ P+I +AG +  K+++    K++     +G IA +AI + RTVV+   E++    Y   L +     ++KA    IT +F+  + +   AG     F +G+ LVA +      +L VF +++ G+  +GQ        A AK +A ++  +I++   ID+ + EG  P+    + + F  + F+YP+R DIPVLQG  L V KGQT+ALVG SGCGKST ++LL+RFYD + G V++    IK +NV+WLR H+GIVSQEP+LFD +IA+NI  G ++   +Q+EI +AA  AN H FI +LP  Y T VG+ G QLSGGQKQRIAIARAL++ P ILLLDEATSALDTESE +VQ ALD A  GRT I+IAHRLST++NADLIV  Q+GRV E GTH +L+A+KG+Y+ +V +Q
Sbjct:  710 YFVVGVFCAIINGGLQPAFAIIFSKIIGVFTRI-DDPETKRQNSN---------------LFSLLFLALGIISFITFFLQGFTFGKAGEILTKRLRYMVFRSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGAIGSRLAVITQNIANLGTGIIISFIYGWQLTLLLLAIVPIIAIAGVVEMKMLSGQALKDKKELEGSGKIATEAIENFRTVVSLTQEQKFEHMYAQSLQVPYRNSLRKAHIFGITFSFTQAMMYFSYAGC----FRFGAYLVAHKLMSFEDVLLVFSAVVFGAMAVGQVSSFAPDYAKAKISAAHIIMIIEKTPLIDSYSTEGLMPNTLEGN-VTFGEVVFNYPTRPDIPVLQGLSLEVKKGQTLALVGSSGCGKSTVVQLLERFYDPLAGKVLLDGKEIKRLNVQWLRAHLGIVSQEPILFDCSIAENIAYGDNSRVVSQEEIVRAAKEANIHAFIESLPNKYSTKVGDKGTQLSGGQKQRIAIARALVRQPHILLLDEATSALDTESEKVVQEALDKAREGRTCIVIAHRLSTIQNADLIVVFQNGRVKEHGTHQQLLAQKGIYFSMVSVQ 1274