TCONS_00014633-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00014633-protein
Unique NameTCONS_00014633-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1616

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00014633-protein ID=TCONS_00014633-protein|Name=TCONS_00014633-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1616bp
MATALKEVTNMESKKSTNKKRLSVERIYQKKTQLEHIILRPDSYIGSAEP
TTQNMWIWDDQKQAIVNKSITFTPGLYKIFDEIIVNAADNKQRDPRMNTI
KVKIDQETNVISVWNNGKGIPVEMHKEENLFVPTLIFGHLLTSSNYDDTE
KKVVGGRNGFGAKLCNIFSTKFTVETGCNGKKFKQVWRNNMGKAETEKIV
DYTGTDFTCITFSPDLKKFGMEKLDDDFVALLKRRAYDMAGVAKGVSVQL
NGDKLKVKTFKDYVNLYLKGTKKSEDDELPKVIHEIVNPRWEVCVTLSET
GFQQASFVNSIATTKGGSHINYLVDQICEKLISAVKKKTGKGGFNIKPFQ
VKSHMWVFANCLIENPTFDSQTKENMTLRKNAFGSACELSDKYIKQVQDC
GILENIMNWVKYKSEAQLNKKTSGSSKHTRLKGVPKLDDANMAGTKNGRD
CTLIVTEGDSAKALAMAGLSIVGRDRYGVFPLRGKLLNVRDASHKQIMDN
AEIGSMCKIIGLQFGKKYTTESDMKNLRYGHLMIMADQDIDGSHIKGLVI
NFIHAHWPDLLKLPFLEEFITPIVKVSKGNQVFSFFSIPEFEEWQGETPN
HKSWRIKYYKGLGTSTSKEGKEYFSNMQRHRIVFDYDGPSCDQALIMAFS
KKLANDRKDWLNTGMNERKMRREADLPEIYLYEKNTKSVTYRDFVNKELI
LFSNADNERSIPSMVDGLKPGQRKVLFTCMKRNDKHEVKVAQLAGSISEL
SAYHHGEMSLMGTIINLAQNYVGSNNLNILVPHGQFGTRHMGGKDSASPR
YICTMMSSLTRLLYPVHDDYVLNFLSEDNQKIEPEWYCPIIPMCLINGAE
GIGTGYSTKVPNHDVREVVENVRRMIAGEEPQAMKPSYKNFTGTIEHVEG
QKYHCTGIVNVIDENTIEITELPIRTWTQPYKETVMDVFLYGTDKVPACI
TDYKEYHTDTTVKFLVSMTTEQLNKAEDEGFYKKFKLESNMLLSNIVLFD
QYGCLKKYNNTLEILQEFYGIRLKKYQERKDFLVGMLQAEASRLENQARF
IMEKIEGKIIIENRTKRDVITKLVERGFDSDPVKIWKNKVSKDTAAVDDE
SEAPVTDYASSTSTTSGGPDFQYLLSMAIMSLSKEKKDELLKQRDQKKEE
LDTLLAKTPEELWSTDLDVFCEELDRVEEQEKMDDAASAAMSKKAQGRLG
AASKKGRKVKVESRDIKKTFDKKPKEPSKAALKKVKDAFGFDTDSVKSED
TASVTSKASEKPASEISEPLSLADRLKKKKQSTLSFKPSNAKKSKKKLGS
DSESEDEKIEDFSDDSDNDNDDGDDDDEYVPKATKTRTAKNKKKLVIDDS
SDSDVDIKPDDDDDENPDVAETRALIERLTPKKDKKKAASSRDSNEGEAA
KKDIFGGGEGSSADPISLEDSPKKDSPKKTKKATTKAAAGGSKKETKSKK
TAASKAKEDPKQKKLSFATKTKKTSTEKFEMSDDSDIEIAPPPAKKKATT
SSAATKKKSTATKSTKSSSVAVKRKTNSSDDDSASEDDKPAKKTKTTKTK
TMPKSNKVRKVAYTVSDDDDESFVADEKVEPLPARDRAGGRRAAAAKKTY
TFSSDDDDDDDDDDFC
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_008188XLOC_008188Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00014633TCONS_00014633Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001241Topo_IIA
IPR001154TopoII_euk
IPR002205Topo_IIA_A/C
IPR003594HATPase_C
IPR006171TOPRIM_domain
IPR031660TOPRIM_C
IPR014721Ribosomal_S5_D2-typ_fold_subgr
IPR024946Arg_repress_C-like
IPR013757Topo_IIA_A_a
IPR013758Topo_IIA_A/C_ab
IPR013506Topo_IIA_bsu_dom2
IPR013759Topo_IIA_cen_dom
IPR018522TopoIIA_CS
IPR034157TOPRIM_TopoII
IPR020568Ribosomal_S5_D2-typ_fold
IPR013760Topo_IIA-like_dom
Vocabulary: Biological Process
TermDefinition
GO:0006265DNA topological change
GO:0006259DNA metabolic process
Vocabulary: Molecular Function
TermDefinition
GO:0003918DNA topoisomerase type II (ATP-hydrolyzing) activity
GO:0003677DNA binding
GO:0005524ATP binding
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006259 DNA metabolic process
biological_process GO:0006265 DNA topological change
molecular_function GO:0005524 ATP binding
molecular_function GO:0003677 DNA binding
molecular_function GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 1034..1054
NoneNo IPR availableCOILSCoilCoilcoord: 1130..1157
NoneNo IPR availableGENE3D3.30.1490.30coord: 585..615
e-value: 1.1E-20
score: 73.1
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1181..1616
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1096..1115
NoneNo IPR availableCDDcd03481TopoIIA_Trans_ScTopoIIAcoord: 258..411
e-value: 6.37578E-72
score: 237.955
NoneNo IPR availableCDDcd00075HATPase_ccoord: 76..176
e-value: 2.71609E-7
score: 49.5674
NoneNo IPR availableCDDcd00187TOP4ccoord: 707..1170
e-value: 2.147E-141
score: 444.317
IPR001241DNA topoisomerase, type IIAPRINTSPR00418TPI2FAMILYcoord: 306..319
score: 63.33
coord: 75..90
score: 56.55
coord: 112..125
score: 58.45
coord: 606..622
score: 54.52
coord: 453..467
score: 56.34
coord: 155..169
score: 60.08
coord: 564..576
score: 39.49
coord: 544..561
score: 45.33
coord: 526..542
score: 59.33
IPR001241DNA topoisomerase, type IIASMARTSM00433topII5coord: 75..666
e-value: 7.8E-288
score: 972.2
IPR001154DNA topoisomerase II, eukaryotic-typePRINTSPR01158TOPISMRASEIIcoord: 1003..1029
score: 47.64
coord: 499..512
score: 51.23
coord: 545..560
score: 67.89
coord: 565..576
score: 81.03
coord: 814..834
score: 47.78
coord: 451..458
score: 83.62
coord: 737..760
score: 71.98
coord: 612..624
score: 77.19
coord: 784..806
score: 70.91
coord: 919..933
score: 77.24
coord: 436..446
score: 73.04
IPR002205DNA topoisomerase, type IIA, subunit A/C-terminalSMARTSM00434topIV4coord: 689..1165
e-value: 9.0E-187
score: 636.4
IPR002205DNA topoisomerase, type IIA, subunit A/C-terminalPFAMPF00521DNA_topoisoIVcoord: 709..1168
e-value: 1.4E-124
score: 416.2
IPR003594Histidine kinase-like ATPase, C-terminal domainSMARTSM00387HKATPase_4coord: 71..218
e-value: 5.5E-5
score: 32.6
IPR003594Histidine kinase-like ATPase, C-terminal domainGENE3D3.30.565.10coord: 31..264
e-value: 1.4E-66
score: 223.6
IPR003594Histidine kinase-like ATPase, C-terminal domainPFAMPF02518HATPase_ccoord: 74..216
e-value: 1.0E-14
score: 55.0
IPR003594Histidine kinase-like ATPase, C-terminal domainSUPERFAMILY55874ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinasecoord: 28..257
IPR006171TOPRIM domainPFAMPF01751Toprimcoord: 452..554
e-value: 6.4E-6
score: 26.2
IPR006171TOPRIM domainPROSITEPS50880TOPRIMcoord: 451..568
score: 17.255
IPR031660C-terminal associated domain of TOPRIMPFAMPF16898TOPRIM_Ccoord: 569..707
e-value: 1.2E-46
score: 158.0
IPR014721Ribosomal protein S5 domain 2-type fold, subgroupGENE3D3.30.230.10coord: 265..425
e-value: 8.3E-50
score: 168.1
IPR024946Arginine repressor C-terminal-like domainGENE3D3.30.1360.40coord: 893..993
e-value: 9.3E-23
score: 79.8
IPR013757Type IIA DNA topoisomerase subunit A, alpha-helical domainGENE3D1.10.268.10coord: 1010..1184
e-value: 1.3E-51
score: 174.2
IPR013758DNA topoisomerase, type IIA, subunit A/ C-terminal, alpha-betaGENE3D3.90.199.10coord: 711..892
e-value: 2.9E-67
score: 225.6
IPR013506DNA topoisomerase, type IIA, subunit B, domain 2PFAMPF00204DNA_gyraseBcoord: 260..422
e-value: 1.1E-23
score: 83.6
IPR013759DNA topoisomerase, type IIA, central domainGENE3D3.40.50.670coord: 426..584
e-value: 1.8E-58
score: 195.9
IPR018522DNA topoisomerase, type IIA, conserved sitePROSITEPS00177TOPOISOMERASE_IIcoord: 455..463
IPR034157DNA topoisomerase 2, TOPRIM domainCDDcd03365TOPRIM_TopoIIAcoord: 451..571
e-value: 1.06505E-71
score: 235.657
IPR020568Ribosomal protein S5 domain 2-type foldSUPERFAMILY54211Ribosomal protein S5 domain 2-likecoord: 249..411
IPR013760DNA topoisomerase, type IIA-like domainSUPERFAMILY56719Type II DNA topoisomerasecoord: 427..1181

Blast
[Close]
BLAST of TCONS_00014633-protein vs. Swiss-Prot (Human)
Match: TOP2B (DNA topoisomerase 2-beta OS=Homo sapiens GN=TOP2B PE=1 SV=3)

HSP 1 Score: 1586.62 bits (4107), Expect = 0.000e+0
Identity = 783/1318 (59.41%), Postives = 973/1318 (73.82%), Query Frame = 0 
Query:   13 SKKSTNKKRLSVERIYQKKTQLEHIILRPDSYIGSAEPTTQNMWIWDDQKQAIVNKSITFTPGLYKIFDEIIVNAADNKQRDPRMNTIKVKIDQETNVISVWNNGKGIPVEMHKEENLFVPTLIFGHLLTSSNYDDTEKKVVGGRNGFGAKLCNIFSTKFTVETGCNGKK--FKQVWRNNMGKAETEKIVDYTGTDFTCITFSPDLKKFGMEKLDDDFVALLKRRAYDMAGVAKGVSVQLNGDKLKVKTFKDYVNLYLKGTKKSEDDELPKVIHEIVNPRWEVCVTLSETGFQQASFVNSIATTKGGSHINYLVDQICEKLISAVKKKTGKGGFNIKPFQVKSHMWVFANCLIENPTFDSQTKENMTLRKNAFGSACELSDKYIKQVQDCGILENIMNWVKYKSEAQLNKKTSGSSKHTRLKGVPKLDDANMAGTKNGRDCTLIVTEGDSAKALAMAGLSIVGRDRYGVFPLRGKLLNVRDASHKQIMDNAEIGSMCKIIGLQFGKKYTTESDMKNLRYGHLMIMADQDIDGSHIKGLVINFIHAHWPDLLKLPFLEEFITPIVKVSKGNQVFSFFSIPEFEEWQGETPNHKSWRIKYYKGLGTSTSKEGKEYFSNMQRHRIVFDYDGPSCDQALIMAFSKKLANDRKDWLNTGMNERKMRREADLPEIYLYEKNTKSVTYRDFVNKELILFSNADNERSIPSMVDGLKPGQRKVLFTCMKRNDKHEVKVAQLAGSISELSAYHHGEMSLMGTIINLAQNYVGSNNLNILVPHGQFGTRHMGGKDSASPRYICTMMSSLTRLLYPVHDDYVLNFLSEDNQKIEPEWYCPIIPMCLINGAEGIGTGYSTKVPNHDVREVVENVRRMIAGEEPQAMKPSYKNFTGTIEHVEGQKYHCTGIVNVIDENTIEITELPIRTWTQPYKETVMDVFLYGTDKVPACITDYKEYHTDTTVKFLVSMTTEQLNKAEDEGFYKKFKLESNMLLSNIVLFDQYGCLKKYNNTLEILQEFYGIRLKKYQERKDFLVGMLQAEASRLENQARFIMEKIEGKIIIENRTKRDVITKLVERGFDSDPVKIWKNKVSKDTAAVDDESEAPVTDYASSTSTTSGGPDFQYLLSMAIMSLSKEKKDELLKQRDQKKEELDTLLAKTPEELWSTDLDVFCEELDRVEEQEKMDDAASAAMSKKA-------------QGRLGAASKKGRKVKVESRDIKKTFDKKPKEPSKAALKKVKDAFGFDTD--------SVKSEDTASVTSKASEKPASEISEPLSLADRLKKKKQSTLSFKPSNAKKSKKKLGSDSESEDE 1307
            + K+ + K+LSVER+YQKKTQLEHI+LRPD+YIGS EP TQ MW++D+    +  + +TF PGLYKIFDEI+VNAADNKQRD  M  IKV ID E+N+IS+WNNGKGIPV  HK E ++VP LIFG LLTSSNYDD EKKV GGRNG+GAKLCNIFSTKFTVET C   K  FKQ W NNM K    KI  + G D+TCITF PDL KF MEKLD D VAL+ RRAYD+AG  +GV V  NG KL V  F+ YV+LY+K  K  E     KVIHE+ N RW+VC+TLSE GFQQ SFVNSIATTKGG H++Y+VDQ+  KLI  VKKK  K G ++KPFQVK+H+WVF NCLIENPTFDSQTKENMTL+  +FGS C+LS+K+ K   +CGI+E+I+NWVK+K++ QLNKK S S K++++KG+PKLDDAN AG K+  +CTLI+TEGDSAK+LA++GL ++GRDRYGVFPLRGK+LNVR+ASHKQIM+NAEI ++ KI+GLQ+ K Y     +K LRYG +MIM DQD DGSHIKGL+INFIH +WP LLK  FLEEFITPIVK SK  Q  SF+SIPEF+EW+    N K+W+IKYYKGLGTST+KE KEYF++M+RHRI+F Y GP  D A+ +AFSKK  +DRK+WL   M +R+ RR   LPE +LY   TK +TY DF+NKELILFSN+DNERSIPS+VDG KPGQRKVLFTC KRNDK EVKVAQLAGS++E+SAYHHGE +LM TI+NLAQN+VGSNN+N+L P GQFGTR  GGKD+ASPRYI TM+S+L RLL+P  DD +L FL +DNQ++EPEWY PIIPM LINGAEGIGTG++ K+PN+D RE+V NVRRM+ G +P  M P+YKNF GTI+ +   +Y  +G + V+D NT+EITELP+RTWTQ YKE V++  L GTDK PA I+DYKEYHTDTTVKF+V MT E+L +AE  G +K FKL++ +  +++VLFD  GCLKKY    +IL+EF+ +RL  Y  RK++LVGML AE+++L NQARFI+EKI+GKI IENR+K+D+I  LV+RG++SDPVK WK   +++ AA +DE++    D +SS S T  GPDF Y+L+M++ SL+KEK +EL+KQRD K  E++ L  K+P +LW  DL  F EELD+VE QE+ D    A MS KA             Q      S  GR++  E   +K    KK  +  K  L        FD +        + +   T SV      KP  E  EP +     + +K  T S KPS  K  K+   SD ES+ E
Sbjct:   40 ANKNDSSKKLSVERVYQKKTQLEHILLRPDTYIGSVEPLTQFMWVYDED-VGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTCIKVSIDPESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQPDLSKFKMEKLDKDIVALMTRRAYDLAGSCRGVKVMFNGKKLPVNGFRSYVDLYVK-DKLDETGVALKVIHELANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKKKN-KAGVSVKPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAASNCGIVESILNWVKFKAQTQLNKKCS-SVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGDSAKSLAVSGLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYDDAESLKTLRYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKNKQELSFYSIPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPEDDAAITLAFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELILFSNSDNERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQALMMTIVNLAQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSTLARLLFPAVDDNLLKFLYDDNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLDGLDPHPMLPNYKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPMLNGTDKTPALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLFDHMGCLKKYETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKITIENRSKKDLIQMLVQRGYESDPVKAWKE--AQEKAAEEDETQNQHDD-SSSDSGTPSGPDFNYILNMSLWSLTKEKVEELIKQRDAKGREVNDLKRKSPSDLWKEDLAAFVEELDKVESQERED--VLAGMSGKAIKGKVGKPKVKKLQLEETMPSPYGRRIIPEITAMKADASKKLLKKKKGDLDTAAVKVEFDEEFSGAPVEGAGEEALTPSVPINKGPKPKREKKEPGT-----RVRKTPTSSGKPSAKKVKKRNPWSDDESKSE 1343
The following BLAST results are available for this feature:
BLAST of TCONS_00014633-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
TOP2B0.000e+059.41DNA topoisomerase 2-beta OS=Homo sapiens GN=TOP2B ... [more]
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