TCONS_00012912-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00012912-protein
Unique NameTCONS_00012912-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length824

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00012912-protein ID=TCONS_00012912-protein|Name=TCONS_00012912-protein|organism=Clytia hemisphaerica|type=polypeptide|length=824bp
MALDLQLKVINNLKGKADRFCRLIFRGVPATSAVLTNCSGDAFFNEEFYW
PLETPIDKEEWLEVRLYNRNKIFQDRLVAAYRLSLAAISEGGTAEVIDNM
IDDRFQILKTEIHMEVTYTKPEPGGVLYDMDQRSYDKKSLGGKSTMTTMT
MMTNRQLNDEEADIYDKEIFHPKIQHPHIVNAMFSDWTISVRIIEAQDLA
GVSLDPSVTITLGENEKKTTVKKQTNNPSWDELFCFDYKCPAQEVLDTIL
KIEVFTGRNMISEGSSIGFFKCDMWYIYDQCDHSFFSKWAPLLDGATTEI
KGYLRLDLQMFGKGDIVKDPPPRKEDQEIDQNLILPPKTNPYRPVHQYQI
KVFKAEGIPQMNTTFMANVKKTFTKKNQDMADPFVEVSFAGVTATTNTEK
NTYNPEFNQLISFTEFFPPLCKRIRFQLKDSDVTSNEVIGTHFLDLDEIS
NEGQKNKGGFMPQFGPTWVNLYGSTRDYALNDEHQDLNNSIGEGIAYRGR
LLIWLDCIEGEPADTGMVEIDDCDPIPPKIMGRDEVYQLFSTFYEASMIP
RKIGTKPISFETTIGEYGFYMKNPSNTDDKTKPRIDFSTPNQDEIDDIDE
DELYQQEKVYVESLTPPTQPLTHEKKYLHVPFGSDKPCCHIKFPFEDQRR
RHYNKILLLKIWTILEENLDELDERVRLNSKGTAKLLKRIMGDVCRQCSL
FIELADGKKTSTHLGKNRLDKERTKMLLICVKQVSEEAALIGEKSKDANC
KVEDLVKQAHNLRKRTKKLLNEPQHGLPDVFVWMLSNNKRIAYTRIPAEE
ILFSRVQSEKGRNCGRVQTIFLRV
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_007243XLOC_007243Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00012912TCONS_00012912Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR012561Ferlin_B-domain
IPR000008C2_dom
IPR012968FerIin_dom
Vocabulary: Cellular Component
TermDefinition
GO:0016021integral component of membrane
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
cellular_component GO:0016021 integral component of membrane
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 745..772
NoneNo IPR availableCDDcd04018C2C_Ferlincoord: 348..499
e-value: 3.67758E-74
score: 239.072
NoneNo IPR availableCDDcd08373C2A_Ferlincoord: 3..129
e-value: 1.00315E-33
score: 125.829
NoneNo IPR availableCDDcd04011C2B_Ferlincoord: 186..294
e-value: 2.31178E-37
score: 135.396
IPR012561Ferlin B-domainSMARTSM01201FerB_2coord: 773..823
e-value: 1.1E-23
score: 94.7
IPR012561Ferlin B-domainPFAMPF08150FerBcoord: 773..823
e-value: 1.9E-22
score: 79.5
IPR000008C2 domainSMARTSM00239C2_3ccoord: 347..458
e-value: 2.8E-11
score: 53.5
coord: 2..97
e-value: 6.0
score: 10.0
coord: 188..286
e-value: 2.6E-11
score: 53.6
IPR000008C2 domainGENE3D2.60.40.150coord: 183..315
e-value: 2.9E-18
score: 65.7
IPR000008C2 domainGENE3D2.60.40.150coord: 1..124
e-value: 3.2E-9
score: 36.4
IPR000008C2 domainPFAMPF00168C2coord: 12..93
e-value: 0.0014
score: 18.8
coord: 347..456
e-value: 1.6E-14
score: 54.0
coord: 187..276
e-value: 2.7E-11
score: 43.5
IPR000008C2 domainGENE3D2.60.40.150coord: 318..483
e-value: 1.6E-17
score: 63.0
IPR000008C2 domainPROSITEPS50004C2coord: 347..443
score: 11.122
IPR000008C2 domainPROSITEPS50004C2coord: 188..271
score: 11.788
IPR000008C2 domainSUPERFAMILY49562C2 domain (Calcium/lipid-binding domain, CaLB)coord: 345..505
IPR000008C2 domainSUPERFAMILY49562C2 domain (Calcium/lipid-binding domain, CaLB)coord: 11..120
IPR000008C2 domainSUPERFAMILY49562C2 domain (Calcium/lipid-binding domain, CaLB)coord: 187..326
IPR012968FerIin domainSMARTSM01202FerI_2coord: 272..339
e-value: 7.7E-19
score: 78.6
IPR012968FerIin domainPFAMPF08151FerIcoord: 297..336
e-value: 1.3E-6
score: 28.3

Blast
[Close]
BLAST of TCONS_00012912-protein vs. Swiss-Prot (Human)
Match: OTOF (Otoferlin OS=Homo sapiens GN=OTOF PE=1 SV=3)

HSP 1 Score: 575.859 bits (1483), Expect = 0.000e+0
Identity = 319/905 (35.25%), Postives = 507/905 (56.02%), Query Frame = 0 
Query:    1 MALDLQLKVINNLKGKADRFCRLIFRGVPATSAVLTNCSGDAFFNEEFYWPLETPIDKEEWLEVRLYNRNKIFQDRLVAAYRLSLAAISEGGTAEVIDNMIDDRFQILKTEIHMEVTYTKPEP-------GGVLYDMDQRSYDKKS-----------------------LGGKSTMTTMTMMTNR------QLNDEEADIYDKEIFHPKIQ---------------------------------HPHIVNAMFSDWTISVRIIEAQDLAGVSLDPSVTITLGENEKKTTVKKQTNNPSWDELFCFDYKCPAQEVLDTILKIEVFTGRNMISEGSSIGFFKCDMWYIYDQCDHSFFSKWAPLLD--GATTEIKGYLRLDLQMFGKGDIVKDPPPRKEDQE--IDQNLILPPKTNPYRPVHQYQIKVFKAEGIPQMNTTFMANVKKTFTKKNQDMADPFVEVSFAGVTATTNTEKNTYNPEFNQLISFTEFFPPLCKRIRFQLKDSDVTSNEVIGTHFLDLDEISNEGQKNKGGFMPQFGPTWVNLYGSTRDYALNDEHQDLNNSIGEGIAYRGRLLIWL-----DCIEGEPADTGMVEIDDCDPIPPKIMGRDEVYQLFSTFYEASMIPRKIGTKPISFETTIGEYGFYMKNPSNTDDKTKPRIDFSTPNQDEIDDI---DEDELYQQEKVYVESLTPPTQPLTHEKKYLHVPFGSDKPCCHIKFPFEDQRRRHYNKILLLKIWTILEENLDELDERVRLNSKGTAKLLKRIMGDVCRQCSLFIELADGKKTSTHLGKNRLDKERTKMLLICVKQVSEEAALIGEKSKDANCKVEDLVKQAHNLRKRTKKLLNEPQHGLPDVFVWMLSNNKRIAYTRIPAEEILFSRVQSEKGRNCGRVQTIFLRV 824
            MAL + LK ++ L+G+ DR  ++ FRG    S VL NC   A F+E F WP+ + ID+ E LE++++N +K+F ++L+  +R+ L  + E    EV D +IDD   I+KT + +EV Y   +        G  L D   +  +K S                         G+S  + M +  NR      Q  DE A +  +++ H  I+                                  P     M  D+ +S+ +IEA+ L G+++DP V + +G+++K T++K+ TN P ++E F FD+      + D I+KI V   +N++  G+ +G FK D+  +Y Q +H F  KWA L D    ++ +KGY++ D+ + GKGD +K P    E  E  I+ NL+LP    P R   ++ +K+++AEG+P+MNT+ MANVKK F  +N+D+ DP+V+V FAG    T+ +K++Y P +N+ + FT+ FPPLCKR++ Q++DSD  ++  IGTHF+DL +ISN+G K   GF+P  GP WVN+YGSTR+Y L DEHQDLN  +GEG+++R RLL+ L     D    E   +  V+++   PI     G+ E + LF  F EASMI R+ G KPI+FE TIG YG  +   S      +PR      +++E+D I    +DE      +   S TPP +P   ++ Y H+P+   KPC +IK  + DQRRR YN  ++  I   LEE L+++ E ++       + L+ ++ ++   C  F+ LAD  K   H  + RLD+ER K  +  ++ + ++A ++  + K     V D ++   N  ++ + L +EPQH +PD+F+WM+SNNKR+AY R+P++++LFS V+ E G++C +V+T+FL++
Sbjct:    1 MALLIHLKTVSELRGRGDRIAKVTFRGQSFYSRVLENCEDVADFDETFRWPVASSIDRNEMLEIQVFNYSKVFSNKLIGTFRMVLQKVVEESHVEVTDTLIDDNNAIIKTSLCVEVRYQATDGTVGSWDDGDFLGDESLQEEEKDSQETDGLLPGSRPSSRPPGEKSFRRAGRSVFSAMKLGKNRSHKEEPQRPDEPAVLEMEDLDHLAIRLGDGLDPDSVSLASVTALTTNVSNKRSKPDIKMEPSAGRPM--DYQVSITVIEARQLVGLNMDPVVCVEVGDDKKYTSMKESTNCPYYNEYFVFDFHVSPDVMFDKIIKISVIHSKNLLRSGTLVGSFKMDVGTVYSQPEHQFHHKWAILSDPDDISSGLKGYVKCDVAVVGKGDNIKTPHKANETDEDDIEGNLLLPEGVPPERQWARFYVKIYRAEGLPRMNTSLMANVKKAFIGENKDLVDPYVQVFFAGQKGKTSVQKSSYEPLWNEQVVFTDLFPPLCKRMKVQIRDSDKVNDVAIGTHFIDLRKISNDGDK---GFLPTLGPAWVNMYGSTRNYTLLDEHQDLNEGLGEGVSFRARLLLGLAVEIVDTSNPELTSSTEVQVEQATPISESCAGKMEEFFLFGAFLEASMIDRRNGDKPITFEVTIGNYGNEVDGLSRP---QRPRPRKEPGDEEEVDLIQNASDDEAGDAGDLASVSSTPPMRPQVTDRNYFHLPYLERKPCIYIKSWWPDQRRRLYNANIMDHIADKLEEGLNDIQEMIKTEKSYPERRLRGVLEELSCGCCRFLSLAD--KDQGHSSRTRLDRERLKSCMRELENMGQQARMLRAQVKRHT--VRDKLRLCQNFLQKLRFLADEPQHSIPDIFIWMMSNNKRVAYARVPSKDLLFSIVEEETGKDCAKVKTLFLKL 893
The following BLAST results are available for this feature:
BLAST of TCONS_00012912-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
OTOF0.000e+035.25Otoferlin OS=Homo sapiens GN=OTOF PE=1 SV=3[more]
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