TCONS_00012724-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00012724-protein
Unique Name	TCONS_00012724-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	554

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00012724-protein ID=TCONS_00012724-protein|Name=TCONS_00012724-protein|organism=Clytia hemisphaerica|type=polypeptide|length=554bp
MEEKTDERTYEDAIQRLNNLQTNASVLANMKKEKEIGKKHLESLPAMRKF
LERSKIDVNKLDRLNIIHVSGTKGKGSVCAFCESILRQYGLKTGFYSSPH
LVEVGERIRINGKPLDRDLFTKYFFQLYDRLSETAVEHDGVMPGYFRFLT
LMAFHVYLQENVDVAVLEVGLGGTYDCTNVINTPIVCGITKLEIDHAAVL
GKEIHQIAAHKAGIMKPDRPAITIEQVKEAEDVLFEKSKEIKTPLYRIPR
LKDFQENIEDFGIKGHHQEVNAVMAIQLARVWCYEKQDILQQRCPEKVEE
LRSIITKSPYENADDESRLDAFNLPPSFIQGLAEAKWLGRCQYHRKDDNF
SYFLDGAHTKSSVEAFISWYLEVSGKYCEGFENISKILVFFITGERDSDI
ILKKLSVIDFEYVVFCPTIFDEKLTNANSDLTNYNRSRDGRLRKCFELEQ
KWLLMNVEGEEEQMETTTGLVNSTQKNSQGVSSSKTGVFPSITSAMKWIK
YSKEQRDEKPPMNDEYNPDYPIELQHSDHVQVLVTGSLHLVGGILKFLGP
GSYQ

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_007136	XLOC_007136	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00012724	TCONS_00012724	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR023600	Folylpolyglutamate_synth_euk
IPR001645	Folylpolyglutamate_synth
IPR013221	Mur_ligase_cen
IPR018109	Folylpolyglutamate_synth_CS
IPR004101	Mur_ligase_C

Vocabulary: **Molecular Function**
Term	Definition
GO:0004326	tetrahydrofolylpolyglutamate synthase activity
GO:0005524	ATP binding
GO:0016874	ligase activity

Vocabulary: **Biological Process**
Term	Definition
GO:0009396	folic acid-containing compound biosynthetic process
GO:0009058	biosynthetic process

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0009058	biosynthetic process
biological_process	GO:0009396	folic acid-containing compound biosynthetic process
molecular_function	GO:0005524	ATP binding
molecular_function	GO:0016874	ligase activity
molecular_function	GO:0004326	tetrahydrofolylpolyglutamate synthase activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 10..30
None	No IPR available	GENE3D	3.90.190.20		coord: 339..554 e-value: 5.1E-27 score: 94.4
IPR023600	Folylpolyglutamate synthase, eukaryota	PIRSF	PIRSF038895	FPGS	coord: 1..552 e-value: 8.2E-148 score: 490.9
IPR001645	Folylpolyglutamate synthetase	TIGRFAM	TIGR01499	TIGR01499	coord: 46..547 e-value: 1.2E-94 score: 315.9
IPR013221	Mur ligase, central	GENE3D	3.40.1190.10		coord: 9..337 e-value: 1.7E-74 score: 250.0
IPR013221	Mur ligase, central	SUPERFAMILY	53623	MurD-like peptide ligases, catalytic domain	coord: 44..285
IPR018109	Folylpolyglutamate synthetase, conserved site	PROSITE	PS01012	FOLYLPOLYGLU_SYNT_2	coord: 166..181
IPR018109	Folylpolyglutamate synthetase, conserved site	PROSITE	PS01011	FOLYLPOLYGLU_SYNT_1	coord: 67..90
IPR004101	Mur ligase, C-terminal	SUPERFAMILY	53244	MurD-like peptide ligases, peptide-binding domain	coord: 486..548 coord: 337..433

Blast

[Close]

BLAST of TCONS_00012724-protein vs. Swiss-Prot (Human)
Match: FOLC (Folylpolyglutamate synthase, mitochondrial OS=Homo sapiens GN=FPGS PE=1 SV=3)

HSP 1 Score: 404.445 bits (1038), Expect = 5.225e-135
Identity = 235/571 (41.16%), Postives = 323/571 (56.57%), Query Frame = 0

Query:   10 YEDAIQRLNNLQTNASVLANMKKEKEIGKKHLESLPAMRKFLERSKIDVNKLDRLNIIHVSGTKGKGSVCAFCESILRQYGLKTGFYSSPHLVEVGERIRINGKPLDRDLFTKYFFQLYDRLSETAVEHDGVMPGYFRFLTLMAFHVYLQENVDVAVLEVGLGGTYDCTNVINTPIVCGITKLEIDHAAVLGKEIHQIAAHKAGIMKPDRPAITIEQVKEAEDVLFEKSKEIKTPLYRIPRLKDFQENIED--FGIKGHHQEVNAVMAIQLARVWCYEKQDILQQRCPEKVEE-LRSIITKSPYENADDESRLDAFNLPPSFIQGLAEAKWLGRCQYHRKDDNFSYFLDGAHTKSSVEAFISWYLEVSGKYCEGFENIS-----KILVFFITGERDSDIILKKLSVIDFEYVVFCPTIFDEKLTNANSDLTNYNRSRDGRLRKCFELEQKWLLMNVEGEEEQMETTTGLVNSTQKNSQG----------VSSSKTGVFPSITSAMKWIKYSKEQRDE--KPPMNDEYNPDYPIE------LQHSDHVQVLVTGSLHLVGGILKFLGPGSYQ 554
            Y+DA++ LN LQTNA  L  +K+++   +  LE   AM  +L RS + V  LDRLNIIHV+GTKGKGS CAF E ILR YGLKTGF+SSPHLV+V ERIRING+P+  +LFTKYF++LY RL ET       MP YFRFLTLMAFHV+LQE VD+AV+EVG+GG YDCTN+I  P+VCG++ L IDH ++LG  + +IA  K GI K   PA T+ Q +    VL +++++I  PLY  P L+  +E       G++G HQ  NA +A+QLA  W  ++QD      P+     L   +  +P        RL           GL   +W GR Q  R+    +++LDGAHT SS +A + W+ +      +G E  S     ++L+F  TG+RD   +LK L    F+Y VFCP +  E  +  N+D  N+  + D  L +C E +Q W  ++    EEQ         S +                 S+ + VF  I+ A++WI    + RD   +PP   +    +P+       L+ +  + VLVTGSLHLVGG+LK L P   Q
Sbjct:   45 YQDAVRMLNTLQTNAGYLEQVKRQRGDPQTQLE---AMELYLARSGLQVEDLDRLNIIHVTGTKGKGSTCAFTECILRSYGLKTGFFSSPHLVQVRERIRINGQPISPELFTKYFWRLYHRLEETKDGSCVSMPPYFRFLTLMAFHVFLQEKVDLAVVEVGIGGAYDCTNIIRKPVVCGVSSLGIDHTSLLGDTVEKIAWQKGGIFKQGVPAFTVLQPEGPLAVLRDRAQQISCPLYLCPMLEALEEGGPPLTLGLEGEHQRSNAALALQLAHCW-LQRQDRHGAGEPKASRPGLLWQLPLAPVFQPTSHMRL-----------GLRNTEWPGRTQVLRRGP-LTWYLDGAHTASSAQACVRWFRQA----LQGRERPSGGPEVRVLLFNATGDRDPAALLKLLQPCQFDYAVFCPNL-TEVSSTGNADQQNFTVTLDQVLLRCLEHQQHWNHLD----EEQASPDLWSAPSPEPGGSASLLLAPHPPHTCSASSLVFSCISHALQWI---SQGRDPIFQPPSPPKGLLTHPVAHSGASILREAAAIHVLVTGSLHLVGGVLKLLEPALSQ 587

The following BLAST results are available for this feature:

BLAST of TCONS_00012724-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00012724-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
FOLC	5.225e-135	41.16	Folylpolyglutamate synthase, mitochondrial OS=Homo...	[more]

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TCONS_00012724-protein (polypeptide) - C. hemisphaerica