TCONS_00012307-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00012307-protein
Unique NameTCONS_00012307-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length348

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00012307-protein ID=TCONS_00012307-protein|Name=TCONS_00012307-protein|organism=Clytia hemisphaerica|type=polypeptide|length=348bp
MAIFSNLVVFALCWFVTSADFVEDFVDNAMEDFGDSPDLKRHRIVMPGVS
PQKPDTVLSYAMEMPDQDLYIIRFEPIGNMKVAHHMLLFSCEEPFLKNKI
WKNGHLHPKKCKDGYKAEMKYAWGKNAPPLQMPKDVAYHIGGSSKAKYFV
LEVHYLHVDSFKDGKTKDHSGFAFITTSKRPKYFAGIYLIQNKHFFIPPH
QKKFHVSAECRYRNKEGMKMHAFRFLVHSHKMGTVISGYLLRNGKYTLIG
KGDPQRPQAFNTVDNEVDIQDGDIVVAQCTYNSMERNRITKYGQTHKDEM
CTFNLMMYYEAKYGDKKPACLKAKGPFTFPKDSDVTLAEMEQRTKGSV
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_006924XLOC_006924Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00012307TCONS_00012307Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000720PHM/PAL
IPR024548Cu2_monoox_C
IPR000323Cu2_ascorb_mOase_N
IPR014784Cu2_ascorb_mOase-like_C
IPR020611Cu2_ascorb_mOase_CS-1
IPR008977PHM/PNGase_F_dom
Vocabulary: Biological Process
TermDefinition
GO:0006518peptide metabolic process
GO:0055114oxidation-reduction process
Vocabulary: Cellular Component
TermDefinition
GO:0016020membrane
Vocabulary: Molecular Function
TermDefinition
GO:0003824catalytic activity
GO:0005507copper ion binding
GO:0016715oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
GO:0004497monooxygenase activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0055114 oxidation-reduction process
biological_process GO:0006518 peptide metabolic process
cellular_component GO:0016020 membrane
molecular_function GO:0003824 catalytic activity
molecular_function GO:0005507 copper ion binding
molecular_function GO:0004497 monooxygenase activity
molecular_function GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000720Peptidylglycine alpha-hydroxylating monooxygenase/peptidyl-hydroxyglycine alpha-amidating lyasePRINTSPR00790PAMONOXGNASEcoord: 73..94
score: 51.95
coord: 292..311
score: 49.29
coord: 246..265
score: 54.29
IPR024548Copper type II ascorbate-dependent monooxygenase, C-terminalPFAMPF03712Cu2_monoox_Ccoord: 185..311
e-value: 3.9E-33
score: 114.1
IPR000323Copper type II, ascorbate-dependent monooxygenase, N-terminalGENE3D2.60.120.310coord: 27..185
e-value: 5.8E-34
score: 116.8
IPR000323Copper type II, ascorbate-dependent monooxygenase, N-terminalPFAMPF01082Cu2_monooxygencoord: 44..160
e-value: 2.1E-19
score: 70.0
IPR014784Copper type II, ascorbate-dependent monooxygenase-like, C-terminalGENE3D2.60.120.230coord: 186..335
e-value: 4.5E-38
score: 129.7
IPR020611Copper type II, ascorbate-dependent monooxygenase, histidine-cluster-1 conserved sitePROSITEPS00084CU2_MONOOXYGENASE_1coord: 84..91
IPR008977PHM/PNGase F domainSUPERFAMILY49742PHM/PNGase Fcoord: 36..181
IPR008977PHM/PNGase F domainSUPERFAMILY49742PHM/PNGase Fcoord: 181..322

Blast
BLAST of TCONS_00012307-protein vs. Swiss-Prot (Human)
Match: AMD (Peptidyl-glycine alpha-amidating monooxygenase OS=Homo sapiens GN=PAM PE=1 SV=2)

HSP 1 Score: 218.009 bits (554), Expect = 9.968e-64
Identity = 113/298 (37.92%), Postives = 165/298 (55.37%), Query Frame = 0
Query:   44 IVMPGVSPQKPDTVLSYAMEMP-DQDLYIIRFEPIGNMKVAHHMLLFSCEEPFLKNKIWKNGHLHPKKCKDGYKAEMKYAWGKNAPPLQMPKDVAYHIGGSSKAKYFVLEVHYLHVDSFKDGKTKDHSGFAFITTSKRPKYFAGIYLIQNKHFFIPPHQKKFHVSAECRYRNKEGMKMHAFRFLVHSHKMGTVISGYLLRNGKYTLIGKGDPQRPQAFNTVDNEVDIQDGDIVVAQCTYNSMERNRITKYGQTHKDEMCTFNLMMYYEAKYGDKKPACLKAKGP---FTFPKDSDVTL 337
            I MPGV+P++ DT    +M +P D++ ++I F+P  +M   HHMLLF C  P      W         C D  KA + YAW +NAPP ++PK V + +GG + +KYFVL+VHY  + +F+D   KD SG +   T       AG+YL+ +    IP  +K  +    C Y+N     MH F + VH+H +G V+SGY +RNG++TLIG+  PQ PQAF  V + VD+  GD++ A+C +    R   T  G T  DEMC   +M Y EAK+      C +   P    T P ++++ +
Sbjct:   61 IRMPGVTPKQSDTYFCMSMRIPVDEEAFVIDFKPRASMDTVHHMLLFGCNMPSSTGSYW---FCDEGTCTD--KANILYAWARNAPPTRLPKGVGFRVGGETGSKYFVLQVHYGDISAFRD-NNKDCSGVSLHLTRLPQPLIAGMYLMMSVDTVIPAGEKVVNSDISCHYKN---YPMHVFAYRVHTHHLGKVVSGYRVRNGQWTLIGRQSPQLPQAFYPVGHPVDVSFGDLLAARCVFTGEGRTEATHIGGTSSDEMCNLYIMYYMEAKHAVSFMTCTQNVAPDMFRTIPPEANIPI 349          
The following BLAST results are available for this feature:
BLAST of TCONS_00012307-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
AMD9.968e-6437.92Peptidyl-glycine alpha-amidating monooxygenase OS=... [more]
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