TCONS_00012299-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00012299-protein
Unique NameTCONS_00012299-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length420

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00012299-protein ID=TCONS_00012299-protein|Name=TCONS_00012299-protein|organism=Clytia hemisphaerica|type=polypeptide|length=420bp
MKSQLYLQMVLLVATSAIFGYDNTESRLHEDLTKGYNTIIRPVEKPVDAI
QVKFDIALQQIIEVNEKEESLVVSVFLRQYWTDVKLRWNMSEYGNIASTK
FSPGSVWVPDLMLYNNAEKSDNFGGGLDQLKTRVIVNNKGQVSWLAPAII
TGECSMNIRHFPFDTQICRLKFGSWTYHGDEIDLQPARDERTFDLGSYSE
HSEWTIENAYLKRNVLYYGCCPEPYPDVTAEFTLKRKPLFYVLNLLLPII
FIGVLTLLAFFLPAESGERISFAVTLMLALTVFMLIVADMIPANSEIVPM
LGIFFTCVMIEMVLMVFAMCYTLNLHFKEPNAENRIGKWTRAIVYNRLAI
YLGVRKRDEEFANANGWSTARKYANGNGPYEEDGFEDVAANKNVVRFTGL
NHNDKSDFEKESTSTKLMKK
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_006918XLOC_006918Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00012299TCONS_00012299Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR006201Neur_channel
IPR006202Neur_chan_lig-bd
IPR006029Neurotrans-gated_channel_TM
IPR018000Neurotransmitter_ion_chnl_CS
Vocabulary: Cellular Component
TermDefinition
GO:0016021integral component of membrane
Vocabulary: Biological Process
TermDefinition
GO:0006811ion transport
Vocabulary: Molecular Function
TermDefinition
GO:0005216ion channel activity
GO:0005230extracellular ligand-gated ion channel activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006811 ion transport
cellular_component GO:0016021 integral component of membrane
molecular_function GO:0005230 extracellular ligand-gated ion channel activity
molecular_function GO:0005216 ion channel activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR006201Neurotransmitter-gated ion-channelPRINTSPR00252NRIONCHANNELcoord: 72..88
score: 37.56
coord: 105..116
score: 46.49
coord: 154..168
score: 48.45
coord: 232..244
score: 42.26
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainPFAMPF02931Neur_chan_LBDcoord: 25..238
e-value: 2.2E-63
score: 213.5
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainGENE3D2.70.170.10coord: 20..241
e-value: 9.5E-70
score: 233.9
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainSUPERFAMILY63712Nicotinic receptor ligand binding domain-likecoord: 23..238
IPR006029Neurotransmitter-gated ion-channel transmembrane domainPFAMPF02932Neur_chan_membcoord: 245..376
e-value: 5.9E-25
score: 88.6
IPR006029Neurotransmitter-gated ion-channel transmembrane domainSUPERFAMILY90112Neurotransmitter-gated ion-channel transmembrane porecoord: 238..364
NoneNo IPR availableGENE3D1.20.58.390coord: 242..412
e-value: 1.5E-29
score: 102.1
IPR018000Neurotransmitter-gated ion-channel, conserved sitePROSITEPS00236NEUROTR_ION_CHANNELcoord: 154..168

Blast
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BLAST of TCONS_00012299-protein vs. Swiss-Prot (Human)
Match: ACHA7 (Neuronal acetylcholine receptor subunit alpha-7 OS=Homo sapiens GN=CHRNA7 PE=1 SV=5)

HSP 1 Score: 274.633 bits (701), Expect = 1.501e-87
Identity = 133/336 (39.58%), Postives = 208/336 (61.90%), Query Frame = 0 
Query:   25 ESRLHEDLTKGYNTIIRPVEKPVDAIQVKFDIALQQIIEVNEKEESLVVSVFLRQYWTDVKLRWNMSEYGNIASTKFSPGSVWVPDLMLYNNAEKSDNFGGGLDQLKTRVIVNNKGQVSWLAPAIITGECSMNIRHFPFDTQICRLKFGSWTYHGDEIDLQPARDERTFDLGSYSEHSEWTIENAYLKRNVLYYGCCPEPYPDVTAEFTLKRKPLFYVLNLLLPIIFIGVLTLLAFFLPAESGERISFAVTLMLALTVFMLIVADMIPANSEIVPMLGIFFTCVMIEMVLMVFAMCYTLNLHFKEPNAENRIGKWTRAIVYNRLAIYLGVRKRDEE 360
            + +L+++L K YN + RPV      + V F ++L QI++V+EK + L  +++L+  WTD  L+WN+SEY  + + +F  G +W PD++LYN+A++  +         T V+VN+ G   +L P I    C +++R FPFD Q C+LKFGSW+Y G  +DLQ     +  D+  Y  + EW +     KR+  +Y CC EPYPDVT   T++R+ L+Y LNLL+P + I  L LL F LPA+SGE+IS  +T++L+LTVFML+VA+++PA S+ VP++  +F   MI + L V      L  H  +P+   ++ KWTR I+ N  A +L +++  E+
Sbjct:   26 QRKLYKELVKNYNPLERPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFD-----ATFHTNVLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQ----MQEADISGYIPNGEWDLVGIPGKRSERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDG-GKMPKWTRVILLNWCAWFLRMKRPGED 351
The following BLAST results are available for this feature:
BLAST of TCONS_00012299-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
ACHA71.501e-8739.58Neuronal acetylcholine receptor subunit alpha-7 OS... [more]
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