Isocitrate/isopropylmalate dehydrogenase (polypeptide) - C. hemisphaerica

Overview
NameIsocitrate/isopropylmalate dehydrogenase
Unique NameTCONS_00012269-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length208

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00012269-protein ID=TCONS_00012269-protein|Name=Isocitrate/isopropylmalate dehydrogenase|organism=Clytia hemisphaerica|type=polypeptide|length=208bp
MVVDGVVQSIKLITRQASERIANYAFDYARSNNRTSVTTVHKANIMRLSD
GLFLQCCREASERNPDIQYNEVFLDTTCLNMVKDPSIYDVLVMPNLYGDI
LSDLGAGLIGGLGLTPSGNIGMDGVAVFEAVHGTAPDIAGQDKANPTALL
LSGVMMLRHMKLNSYADTIENACFKTIAEGKATTGDLGGRSSCTDYTNEI
IRHIEESS
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_006908XLOC_006908Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00012269TCONS_00012269Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR024084IsoPropMal-DH-like_dom
IPR019818IsoCit/isopropylmalate_DH_CS
Vocabulary: Biological Process
TermDefinition
GO:0055114oxidation-reduction process
Vocabulary: Molecular Function
TermDefinition
GO:0016616oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0051287NAD binding
GO:0000287magnesium ion binding
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0055114 oxidation-reduction process
molecular_function GO:0000287 magnesium ion binding
molecular_function GO:0051287 NAD binding
molecular_function GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR024084Isopropylmalate dehydrogenase-like domainSMARTSM01329Iso_dh_2coord: 1..200
e-value: 6.1E-52
score: 188.5
IPR024084Isopropylmalate dehydrogenase-like domainPFAMPF00180Iso_dhcoord: 6..200
e-value: 1.1E-69
score: 235.2
NoneNo IPR availableGENE3D3.40.718.10coord: 1..206
e-value: 1.7E-86
score: 289.9
NoneNo IPR availableSUPERFAMILY53659Isocitrate/Isopropylmalate dehydrogenase-likecoord: 4..204
IPR019818Isocitrate/isopropylmalate dehydrogenase, conserved sitePROSITEPS00470IDH_IMDHcoord: 95..114

Blast
[Close]
BLAST of Isocitrate/isopropylmalate dehydrogenase vs. Swiss-Prot (Human)
Match: IDH3A (Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial OS=Homo sapiens GN=IDH3A PE=1 SV=1)

HSP 1 Score: 308.531 bits (789), Expect = 9.153e-106
Identity = 145/206 (70.39%), Postives = 176/206 (85.44%), Query Frame = 0 
Query:    1 MVVDGVVQSIKLITRQASERIANYAFDYARSNNRTSVTTVHKANIMRLSDGLFLQCCREASERNPDIQYNEVFLDTTCLNMVKDPSIYDVLVMPNLYGDILSDLGAGLIGGLGLTPSGNIGMDGVAVFEAVHGTAPDIAGQDKANPTALLLSGVMMLRHMKLNSYADTIENACFKTIAEGKATTGDLGGRSSCTDYTNEIIRHIEE 206
            ++VDGVVQSIKLIT  AS+RIA +AF+YAR+N+R++VT VHKANIMR+SDGLFLQ CRE +E   DI++NE++LDT CLNMV+DPS +DVLVMPNLYGDILSDL AGLIGGLG+TPSGNIG +GVA+FE+VHGTAPDIAG+D ANPTALLLS VMMLRHM L  +A  IE ACF TI +GK+ T DLGG + C+D+T EI R +++
Sbjct:  159 VIVDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVHKANIMRMSDGLFLQKCREVAESCKDIKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAARIEAACFATIKDGKSLTKDLGGNAKCSDFTEEICRRVKD 364
The following BLAST results are available for this feature:
BLAST of Isocitrate/isopropylmalate dehydrogenase vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
IDH3A9.153e-10670.39Isocitrate dehydrogenase [NAD] subunit alpha, mito... [more]
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