TCONS_00010297-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00010297-protein
Unique NameTCONS_00010297-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length477

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00010297-protein ID=TCONS_00010297-protein|Name=TCONS_00010297-protein|organism=Clytia hemisphaerica|type=polypeptide|length=477bp
MIIRDGVFTRSLYVLVLTIVFLISTCSCGGSKKFPLMKRRNQATKDVVTT
ENLKGRPGQGYYIAILFGTPPQRINVLVDTGSSNFAIASRPHPYLPLYFH
ADQSKTFVPLNRPVAVPYTQGNWQGELGTDFIQFIDALNVTVNVNVALIK
SSENFFINGSNWEGILGLGYTHLSKPDSSVIPVFDQFVIDNVVDDTFSMQ
LCSSSELDPSAEPTVAGTLVFGETDEDLYKGDLFYTPIVKKWYYEVIITD
FAVNGVSLGLNCKKYNYDKTIVDSGTTNLRVPEDVFNAILVHLKKYDRLG
VPDEFWIGRQMMCWNYDKTPWEEFPDMSISLLSSVSSSKEFILKITPQLY
LRETIERGPLPGQHCYKFAITKAERGTVIGAVIMEGFYVVFDRENVQVGF
AATTCGAEGRLNPRSSVSGPFNRADPVDCEYIETEPADSALLTVAYVMAG
VCGLCLLPVFILLGQASCKRRLVEYDG
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_005783XLOC_005783Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00010297TCONS_00010297Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR009120BACE1
IPR001461Aspartic_peptidase_A1
IPR009119BACE
IPR033121PEPTIDASE_A1
IPR021109Peptidase_aspartic_dom
IPR001969Aspartic_peptidase_AS
Vocabulary: Molecular Function
TermDefinition
GO:0004190aspartic-type endopeptidase activity
Vocabulary: Cellular Component
TermDefinition
GO:0016021integral component of membrane
Vocabulary: Biological Process
TermDefinition
GO:0006508proteolysis
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006508 proteolysis
cellular_component GO:0016021 integral component of membrane
molecular_function GO:0004190 aspartic-type endopeptidase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR009120Beta-secretase BACE1PRINTSPR01816BACE1coord: 420..439
score: 37.08
coord: 344..358
score: 40.0
coord: 82..97
score: 55.73
coord: 441..461
score: 53.17
IPR001461Aspartic peptidase A1 familyPRINTSPR00792PEPSINcoord: 270..281
score: 40.71
coord: 377..392
score: 32.48
coord: 67..87
score: 47.83
coord: 217..230
score: 34.85
IPR009119Beta-secretase BACEPRINTSPR01815BACEFAMILYcoord: 133..156
score: 40.72
coord: 340..354
score: 43.33
coord: 402..425
score: 31.82
coord: 438..459
score: 44.83
coord: 85..107
score: 39.72
coord: 252..271
score: 51.82
coord: 301..324
score: 47.35
IPR033121Peptidase family A1 domainPFAMPF00026Aspcoord: 61..402
e-value: 1.1E-39
score: 136.6
IPR033121Peptidase family A1 domainPROSITEPS51767PEPTIDASE_A1coord: 61..401
score: 44.171
IPR021109Aspartic peptidase domainGENE3D2.40.70.10coord: 189..448
e-value: 5.1E-44
score: 149.7
IPR021109Aspartic peptidase domainGENE3D2.40.70.10coord: 61..188
e-value: 7.5E-25
score: 87.2
IPR021109Aspartic peptidase domainSUPERFAMILY50630Acid proteasescoord: 49..407
IPR001969Aspartic peptidase, active sitePROSITEPS00141ASP_PROTEASEcoord: 76..87
NoneNo IPR availablePROSITEPS51257PROKAR_LIPOPROTEINcoord: 1..28
score: 5.0

Blast
[Close]
BLAST of TCONS_00010297-protein vs. Swiss-Prot (Human)
Match: BACE1 (Beta-secretase 1 OS=Homo sapiens GN=BACE1 PE=1 SV=3)

HSP 1 Score: 407.912 bits (1047), Expect = 1.406e-138
Identity = 202/429 (47.09%), Postives = 274/429 (63.87%), Query Frame = 0 
Query:   47 VVTTENLKGRPGQGYYIAILFGTPPQRINVLVDTGSSNFAIASRPHPYLPLYFHADQSKTFVPLNRPVAVPYTQGNWQGELGTDFIQFIDALNVTVNVNVALIKSSENFFINGSNWEGILGLGYTHLSKPDSSVIPVFDQFVIDNVVDDTFSMQLCSSSELDPSAE--PTVAGTLVFGETDEDLYKGDLFYTPIVKKWYYEVIITDFAVNGVSLGLNCKKYNYDKTIVDSGTTNLRVPEDVFNAILVHLKKYDRL-GVPDEFWIGRQMMCWNYDKTPWEEFPDMSISLLSSVSSSKEFILKITPQLYLRETIERGPLPGQHCYKFAITKAERGTVIGAVIMEGFYVVFDRENVQVGFAATTCGAEGRLNPRSSVSGPFNRADPVDCEYIETEPADSALLTVAYVMAGVCGLCLLPVFILLGQASCKRRL 472
            V   +NL+G+ GQGYY+ +  G+PPQ +N+LVDTGSSNFA+ + PHP+L  Y+    S T+  L + V VPYTQG W+GELGTD +      NVTV  N+A I  S+ FFINGSNWEGILGL Y  +++PD S+ P FD  V    V + FS+QLC +      +E   +V G+++ G  D  LY G L+YTPI ++WYYEVII    +NG  L ++CK+YNYDK+IVDSGTTNLR+P+ VF A +  +K        PD FW+G Q++CW    TPW  FP +S+ L+  V +++ F + I PQ YLR  +E        CYKFAI+++  GTV+GAVIMEGFYVVFDR   ++GFA + C         ++V GPF   D  DC Y   +  +S L+T+AYVMA +C L +LP+ +++ Q  C R L
Sbjct:   61 VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSSTYRDLRKGVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGILGLAYAEIARPDDSLEPFFDSLVKQTHVPNLFSLQLCGAGFPLNQSEVLASVGGSMIIGGIDHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKKVFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEV-TNQSFRITILPQQYLR-PVEDVATSQDDCYKFAISQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSACHVHDEFR-TAAVEGPFVTLDMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQWRCLRCL 486
The following BLAST results are available for this feature:
BLAST of TCONS_00010297-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
BACE11.406e-13847.09Beta-secretase 1 OS=Homo sapiens GN=BACE1 PE=1 SV=... [more]
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