retinoid X receptor (polypeptide) - C. hemisphaerica

Overview
Nameretinoid X receptor
Unique NameTCONS_00006052-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length455

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00006052-protein ID=TCONS_00006052-protein|Name=retinoid X receptor|organism=Clytia hemisphaerica|type=polypeptide|length=455bp
MDTMISSSSDEPYLTSDGAISSTTSSMTQSRTAESYTSLLKDDTFTTQTP
ISPQSSISSIKSPDSTTLQLNSPPSDMFSPPPSAGSSNTIDTNPSTSDIY
LGASPVKIARTTSSTSSSFSNEQCTVCGDKATYSVFGAASCDSCGGFFKR
AVKNSREYTCETGKRDCLLNKKTRNRCKACRLQRCYKVGMSSNAAKEYAD
REKMEKTRKKEDKIQQVVSSSHSSSPMEAVQTIEIKEINDAELYVDPKIN
AFANIAVDPIRQLCLAADKQLASLAEWAKRMPHFTTLNLSDQVKLLQWNW
AELLIGGFCYRSSAVSDGILLATGLHLSRDNLQKAGVGAVVNKLFSEVIN
KMQKLQIDVSEWGCLRAIMLFAPDTKELTDPHQVEAIRQRYVATLCDYHK
KQYKEDPNRLGNLLLRLPPLKAIALQVLEHLFFFKLIGDVPIDTFLMEML
DVDSH
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_003449XLOC_003449Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00006052TCONS_00006052Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001628Znf_hrmn_rcpt
IPR000003Retinoid-X_rcpt/HNF4
IPR001723Nuclear_hrmn_rcpt
IPR000536Nucl_hrmn_rcpt_lig-bd
IPR013088Znf_NHR/GATA
Vocabulary: Molecular Function
TermDefinition
GO:0043565sequence-specific DNA binding
GO:0003700transcription factor activity, sequence-specific DNA binding
GO:0008270zinc ion binding
GO:0003677DNA binding
GO:0003707steroid hormone receptor activity
Vocabulary: Biological Process
TermDefinition
GO:0006355regulation of transcription, DNA-templated
GO:0043401steroid hormone mediated signaling pathway
Vocabulary: Cellular Component
TermDefinition
GO:0005634nucleus
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006355 regulation of transcription, DNA-templated
biological_process GO:0043401 steroid hormone mediated signaling pathway
cellular_component GO:0005634 nucleus
molecular_function GO:0003677 DNA binding
molecular_function GO:0043565 sequence-specific DNA binding
molecular_function GO:0003707 steroid hormone receptor activity
molecular_function GO:0003700 transcription factor activity, sequence-specific DNA binding
molecular_function GO:0008270 zinc ion binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001628Zinc finger, nuclear hormone receptor-typePRINTSPR00047STROIDFINGERcoord: 182..190
score: 52.0
coord: 124..140
score: 41.25
coord: 174..182
score: 61.54
coord: 140..155
score: 44.65
IPR001628Zinc finger, nuclear hormone receptor-typeSMARTSM00399c4goldcoord: 121..193
e-value: 1.9E-24
score: 97.2
IPR001628Zinc finger, nuclear hormone receptor-typePFAMPF00105zf-C4coord: 123..191
e-value: 2.4E-22
score: 79.0
IPR001628Zinc finger, nuclear hormone receptor-typePROSITEPS51030NUCLEAR_REC_DBD_2coord: 121..197
score: 17.994
IPR000003Retinoid X receptor/HNF4PRINTSPR00545RETINOIDXRcoord: 384..403
score: 36.16
coord: 317..342
score: 49.66
coord: 343..361
score: 31.2
IPR001723Nuclear hormone receptorPRINTSPR00398STRDHORMONERcoord: 287..303
score: 43.24
coord: 412..429
score: 34.22
coord: 186..196
score: 35.84
coord: 266..287
score: 37.39
coord: 355..370
score: 38.97
IPR000536Nuclear hormone receptor, ligand-binding domainSMARTSM00430holicoord: 265..424
e-value: 3.8E-36
score: 136.1
IPR000536Nuclear hormone receptor, ligand-binding domainPFAMPF00104Hormone_recepcoord: 262..437
e-value: 3.8E-29
score: 101.6
IPR000536Nuclear hormone receptor, ligand-binding domainSUPERFAMILY48508Nuclear receptor ligand-binding domaincoord: 202..453
NoneNo IPR availableGENE3D1.10.565.10coord: 185..452
e-value: 3.5E-69
score: 232.6
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..96
NoneNo IPR availableCDDcd06916NR_DBD_likecoord: 124..194
e-value: 8.98077E-29
score: 106.877
NoneNo IPR availableSUPERFAMILY57716Glucocorticoid receptor-like (DNA-binding domain)coord: 121..200
IPR013088Zinc finger, NHR/GATA-typeGENE3D3.30.50.10coord: 116..184
e-value: 4.6E-24
score: 84.0

Blast
[Close]
BLAST of retinoid X receptor vs. Swiss-Prot (Human)
Match: RXRG (Retinoic acid receptor RXR-gamma OS=Homo sapiens GN=RXRG PE=1 SV=1)

HSP 1 Score: 348.977 bits (894), Expect = 2.208e-116
Identity = 177/407 (43.49%), Postives = 254/407 (62.41%), Query Frame = 0 
Query:   52 SPQSSISSIKSPDSTTLQLNSPPSDMFSPPPSAGSSNTIDTNPSTSDI--YLGASPVKIARTTSSTSSSFSNEQCTVCGDKATYSVFGAASCDSCGGFFKRAVKNSREYTCETGKRDCLLNKKTRNRCKACRLQRCYKVGMSSNAAKEYADREKMEKTRKKEDKIQQVVSSSHSSSPMEAVQTIEIKEINDAELYVDPKINAFANIAV-----DPIRQLCLAADKQLASLAEWAKRMPHFTTLNLSDQVKLLQWNWAELLIGGFCYRSSAVSDGILLATGLHLSRDNLQKAGVGAVVNKLFSEVINKMQKLQIDVSEWGCLRAIMLFAPDTKELTDPHQVEAIRQRYVATLCDYHKKQYKEDPNRLGNLLLRLPPLKAIALQVLEHLFFFKLIGDVPIDTFLMEMLD 451
            SP   I+S   P S  L   +PP      PPS+   N +++  S+ DI    G   +      S++  S     C +CGD+++   +G  SC+ C GFFKR ++    YTC   K DCL++K+ RNRC+ CR Q+C  +GM     K  A +E+ +++R++ +   +  +S H   P+E         I +AEL V+PK  ++ ++ +     DP+  +C AADKQL +L EWAKR+PHF+ L L DQV LL+  W ELLI  F +RS +V DGILLATGLH+ R +   AGVG++ +++ +E+++KM+ +Q+D SE GCLRAI+LF PD K L++P +VE +R++  ATL  Y K++Y E P R   LLLRLP L++I L+ LEHLFFFKLIGD PIDTFLMEML+
Sbjct:   68 SPYRVITSAMGPPSGALA--APPGINLVAPPSS-QLNVVNSVSSSEDIKPLPGLPGIGNMNYPSTSPGSLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNK-DCLIDKRQRNRCQYCRYQKCLVMGM-----KREAVQEERQRSRERAESEAECATSGHEDMPVE--------RILEAELAVEPKTESYGDMNMENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILLRAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKDMQMDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLRLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLE 457
The following BLAST results are available for this feature:
BLAST of retinoid X receptor vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
RXRG2.208e-11643.49Retinoic acid receptor RXR-gamma OS=Homo sapiens G... [more]
back to top