TCONS_00050538-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00050538-protein
Unique Name	TCONS_00050538-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	456

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00050538-protein ID=TCONS_00050538-protein|Name=TCONS_00050538-protein|organism=Clytia hemisphaerica|type=polypeptide|length=456bp
SEKVNKLLVLIAVVMDSRDREFLRSNRREICLIDFDAPNVASKLHELGIL
SKNENEMISLEEKDLRQKERLLDILPRRGPKAFAKFIETAKELRILKLYK
ILGGDPALYGDGESKVSSEETDKTKMEDDRTDGPPRQLPLKEQNPDDEKP
TEDTVDTPPETETDGRPSLFGGSGKKKTKTSSTSEGDERVPLSPSSFIEA
PIDLKECYAMQSTPRGHFILVNNKHFLPSSGMENYPRNGTDVDGAAITEL
FQEMGFLVEAHSNLSVYEMRKVFKQAAHKDYSGVSCLTCCILSHGQEGVI
YGTDGTIEIREITSFFHGTNLSGKPKLFFFQACQGSDYMDSVTPDEVMET
DGPASEGNDITLPSEADFLYAYSTVPGYYSWRNSQRGSWFIQSICEVFRK
HAHKMDVVRMLTRVNAIVSTKKSQTGQRASHHKRQISSIVTQLRKELYFF
XVKSHL

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_032007	XLOC_032007	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00050538	TCONS_00050538	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR015917	Pept_C14A
IPR001315	CARD
IPR033139	Caspase_cys_AS
IPR001309	Pept_C14_p20
IPR002138	Pept_C14_p10
IPR011029	DEATH-like_dom
IPR029030	Caspase-like_dom

Vocabulary: **Molecular Function**
Term	Definition
GO:0008234	cysteine-type peptidase activity
GO:0004197	cysteine-type endopeptidase activity

Vocabulary: **Biological Process**
Term	Definition
GO:0042981	regulation of apoptotic process
GO:0006508	proteolysis

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0006508	proteolysis
biological_process	GO:0042981	regulation of apoptotic process
molecular_function	GO:0004197	cysteine-type endopeptidase activity
molecular_function	GO:0008234	cysteine-type peptidase activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR015917	Peptidase C14A, caspase catalytic domain	PRINTS	PR00376	IL1BCENZYME	coord: 214..227 score: 32.03 coord: 255..273 score: 25.84 coord: 318..336 score: 52.15 coord: 287..295 score: 48.48 coord: 441..450 score: 42.73 coord: 380..391 score: 64.9
IPR015917	Peptidase C14A, caspase catalytic domain	SMART	SM00115	caspase_2	coord: 207..451 e-value: 4.9E-81 score: 285.2
IPR015917	Peptidase C14A, caspase catalytic domain	CDD	cd00032	CASc	coord: 207..450 e-value: 1.85466E-91 score: 279.1
None	No IPR available	PIRSF	PIRSF038001	Caspase_ICE	coord: 15..451 e-value: 8.0E-87 score: 289.6
None	No IPR available	GENE3D	3.40.50.1460		coord: 173..345 e-value: 7.8E-25 score: 87.2
None	No IPR available	PFAM	PF00656	Peptidase_C14	coord: 219..449 e-value: 2.4E-38 score: 132.4
None	No IPR available	GENE3D	1.10.533.10		coord: 14..128 e-value: 3.8E-12 score: 45.8
None	No IPR available	GENE3D	3.30.70.1470		coord: 353..456 e-value: 4.2E-35 score: 119.2
None	No IPR available	CDD	cd01671	CARD	coord: 23..88 e-value: 1.22395E-13 score: 65.2305
IPR001315	CARD domain	PFAM	PF00619	CARD	coord: 39..100 e-value: 1.4E-7 score: 31.3
IPR001315	CARD domain	PROSITE	PS50209	CARD	coord: 15..92 score: 12.49
IPR033139	Peptidase family C14A, cysteine active site	PROSITE	PS01122	CASPASE_CYS	coord: 324..335
IPR001309	Peptidase C14, p20 domain	PROSITE	PS50208	CASPASE_P20	coord: 214..337 score: 34.615
IPR002138	Peptidase C14, caspase non-catalytic subunit p10	PROSITE	PS50207	CASPASE_P10	coord: 358..451 score: 38.444
IPR011029	Death-like domain	SUPERFAMILY	47986	DEATH domain	coord: 15..104
IPR029030	Caspase-like domain	SUPERFAMILY	52129	Caspase-like	coord: 205..450

Blast

[Close]

BLAST of TCONS_00050538-protein vs. Swiss-Prot (Human)
Match: CASP7 (Caspase-7 OS=Homo sapiens GN=CASP7 PE=1 SV=1)

HSP 1 Score: 214.157 bits (544), Expect = 4.697e-66
Identity = 123/320 (38.44%), Postives = 183/320 (57.19%), Query Frame = 0

Query:  137 QLPLKEQNPDDEKPTEDTVDTPPETETDGRPSLFGGSGKKKTKTSSTSEGDERVPLSPSSFIEAPIDLKECYAMQSTPRGHFILVNNKHFLPSSGMENYPRNGTDVDGAAITELFQEMGFLVEAHSNLSVYEMRKVFKQAAHKDYSGVSCLTCCILSHGQEGVIYGTDGTIEIREITSFFHG---TNLSGKPKLFFFQACQGSDYMDSVTPDEVMETDGPASEGND---ITLPSEADFLYAYSTVPGYYSWRNSQRGSWFIQSICEVFRKHAHKMDVVRMLTRVNAIVSTK-KSQTGQRASHHKRQISSIVTQLRKELYF 449
            Q  ++EQ  +D    ED+VD  P+  +   PSLF    K  T  S  +  D RVP                Y M     G  I++NNK+F   +GM    RNGTD D  A+ + F+ +GF V  +++ S  +M+ + K+A+ +D++  +C  C +LSHG+E VIYG DG   I+++T+ F G     L  KPKLFF QAC+G++  D +  D      GP ++ +      +P EADFL+AYSTVPGYYSWR+  RGSWF+Q++C +  +H   ++++++LTRVN  V+   +SQ+     H K+QI  +V+ L KELYF
Sbjct:    5 QGCIEEQGVEDS-ANEDSVDAKPD-RSSFVPSLFSKKKKNVTMRSIKTTRD-RVPTYQ-------------YNMNFEKLGKCIIINNKNFDKVTGMG--VRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQDLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKLFFIQACRGTELDDGIQADS-----GPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSWFVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELYF 301

The following BLAST results are available for this feature:

BLAST of TCONS_00050538-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00050538-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
CASP7	4.697e-66	38.44	Caspase-7 OS=Homo sapiens GN=CASP7 PE=1 SV=1	[more]

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TCONS_00050538-protein (polypeptide) - C. hemisphaerica