TCONS_00022872-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00022872-protein
Unique NameTCONS_00022872-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length926

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00022872-protein ID=TCONS_00022872-protein|Name=TCONS_00022872-protein|organism=Clytia hemisphaerica|type=polypeptide|length=926bp
CFLESTSYPITSVNTIYADAKFTGRYCNALALPNPDCGENITVNAIILDT
FPNTKTHNTPTEQEVNLPVMDDLKVPIPQKDGKPSFFEAKQTITYDNKLN
KKYIRYLFDSKMGCGSISGFEIYYYKCPSATSSLAVFGVNNAPSLSDDAK
EYEGKCVDNAVEVGNEKLTMKCAWNGTVQSITGQCVCLKGYEKENNQCKI
CDSQHFKPTQGNEKCTRCGLNSRSSIDKTTCNCLHKYKREVIEINNPLAV
CYKIPDVPSAISFSNITRNSVEITWSHPSQINKTNIYIVDCNDCPSGVFP
KTTTDKFITINGLGAFADYEISVTFSSEVSRMIGENQTSKFESFKTLPGP
PGKVRNLRQKSLDGGKVELSWDPPFAKGGNLITYLLTYGGSTKKTTLTTY
IIESDAEDQTFTVKIAAQVSVGGQLLTGESSTFKDKISVKGGVALDMAIG
VGVGVVLLVIIIAIIAFYIYRKKHPPYAQAVRLENGQVELKTRFLSFPGS
KLYVDPMTYGAVDEAVQEFAFELDQKSLTIGQLLGGGEFADVYKGTLFKN
GKSKEVAIKTLKQSATKHDRDDFLSEAAIVGQFTDPNVISLEGVVLKERP
NVIVLEYMANGSLDKYLQKHDMQLTNLQLLGMARGVASGMKYLNELGFIH
RDLAARNILVDEYRVCKVSDFGMSREIKVDETYDTQGGKIPVRWTAPESI
QYKKFTTASDAWSYGILLWEIMSYGERPYWDWGNYEVLERLNQGYRLPPP
MNCPKVIHDLMLHCWKKDRTKRPRMVEIRDQIEKWIRSPDLLETTVTVVT
KTDENLDYTVLQTINKWLDAIGMAKYTENFIEKGYATPRQILSLTLEDLE
ELGIAPIGHRKKIFKAIQNTKQQVEQRHNSVSVGTGGRKKTFSLPKKGGC
CLLKACGSLYGSFLPIYNNQVMEWLI
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_012853XLOC_012853Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00022872TCONS_00022872Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001245Ser-Thr/Tyr_kinase_cat_dom
IPR001660SAM
IPR003961FN3_dom
IPR020635Tyr_kinase_cat_dom
IPR027936Eph_TM
IPR013783Ig-like_fold
IPR016257Tyr_kinase_ephrin_rcpt
IPR008266Tyr_kinase_AS
IPR017441Protein_kinase_ATP_BS
IPR000719Prot_kinase_dom
IPR001090Ephrin_rcpt_lig-bd_dom
IPR013761SAM/pointed
IPR011009Kinase-like_dom
Vocabulary: Molecular Function
TermDefinition
GO:0004672protein kinase activity
GO:0005515protein binding
GO:0004713protein tyrosine kinase activity
GO:0005524ATP binding
GO:0005003ephrin receptor activity
Vocabulary: Biological Process
TermDefinition
GO:0006468protein phosphorylation
GO:0007169transmembrane receptor protein tyrosine kinase signaling pathway
Vocabulary: Cellular Component
TermDefinition
GO:0005887integral component of plasma membrane
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006468 protein phosphorylation
biological_process GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
cellular_component GO:0005887 integral component of plasma membrane
molecular_function GO:0005524 ATP binding
molecular_function GO:0005003 ephrin receptor activity
molecular_function GO:0005515 protein binding
molecular_function GO:0004672 protein kinase activity
molecular_function GO:0004713 protein tyrosine kinase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPRINTSPR00109TYRKINASEcoord: 690..700
score: 61.48
coord: 642..660
score: 65.18
coord: 709..731
score: 57.7
coord: 605..618
score: 45.8
coord: 753..775
score: 39.46
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPFAMPF07714Pkinase_Tyrcoord: 528..781
e-value: 1.6E-91
score: 306.1
IPR001660Sterile alpha motif domainSMARTSM00454SAM_4coord: 806..873
e-value: 6.0E-17
score: 72.3
IPR001660Sterile alpha motif domainPFAMPF07647SAM_2coord: 809..869
e-value: 4.0E-17
score: 62.0
IPR001660Sterile alpha motif domainPROSITEPS50105SAM_DOMAINcoord: 809..873
score: 19.813
IPR003961Fibronectin type IIISMARTSM00060FN3_2coord: 351..424
e-value: 0.0074
score: 25.5
coord: 255..332
e-value: 0.025
score: 23.7
IPR003961Fibronectin type IIIPROSITEPS50853FN3coord: 257..349
score: 10.825
IPR003961Fibronectin type IIIPROSITEPS50853FN3coord: 350..442
score: 9.05
IPR003961Fibronectin type IIICDDcd00063FN3coord: 255..346
e-value: 1.96327E-7
score: 49.0319
IPR003961Fibronectin type IIICDDcd00063FN3coord: 351..432
e-value: 7.37103E-5
score: 40.9427
IPR003961Fibronectin type IIISUPERFAMILY49265Fibronectin type IIIcoord: 254..422
IPR020635Tyrosine-protein kinase, catalytic domainSMARTSM00219tyrkin_6coord: 528..782
e-value: 4.9E-126
score: 434.7
NoneNo IPR availableGENE3D1.20.5.510coord: 434..474
e-value: 2.0E-4
score: 20.7
NoneNo IPR availableGENE3D3.30.200.20coord: 2..127
e-value: 0.0018
score: 18.0
NoneNo IPR availableGENE3D1.10.150.50coord: 806..869
e-value: 8.6E-18
score: 63.9
NoneNo IPR availableGENE3D2.60.40.1770coord: 128..185
e-value: 7.5E-7
score: 28.7
NoneNo IPR availableGENE3D3.30.200.20coord: 510..605
e-value: 3.4E-22
score: 77.9
NoneNo IPR availableGENE3D1.10.510.10coord: 606..788
e-value: 5.9E-47
score: 158.8
IPR027936Ephrin receptor, transmembrane domainPFAMPF14575EphA2_TMcoord: 450..524
e-value: 2.0E-10
score: 41.2
IPR013783Immunoglobulin-like foldGENE3D2.60.40.10coord: 348..433
e-value: 2.6E-9
score: 36.6
IPR013783Immunoglobulin-like foldGENE3D2.60.40.10coord: 253..347
e-value: 8.4E-11
score: 41.5
IPR016257Ephrin receptor type-A /type-BPIRSFPIRSF000666TyrPK_ephrin_receptorcoord: 2..882
e-value: 6.8E-222
score: 737.0
IPR008266Tyrosine-protein kinase, active sitePROSITEPS00109PROTEIN_KINASE_TYRcoord: 648..660
IPR017441Protein kinase, ATP binding sitePROSITEPS00107PROTEIN_KINASE_ATPcoord: 534..559
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 528..786
score: 37.404
IPR001090Ephrin receptor ligand binding domainPROSITEPS51550EPH_LBDcoord: 1..132
score: 13.761
IPR013761Sterile alpha motif/pointed domainSUPERFAMILY47769SAM/Pointed domaincoord: 806..876
IPR011009Protein kinase-like domainSUPERFAMILY56112Protein kinase-like (PK-like)coord: 521..802

Blast
[Close]
BLAST of TCONS_00022872-protein vs. Swiss-Prot (Human)
Match: EPHA7 (Ephrin type-A receptor 7 OS=Homo sapiens GN=EPHA7 PE=1 SV=3)

HSP 1 Score: 517.694 bits (1332), Expect = 1.053e-168
Identity = 325/919 (35.36%), Postives = 483/919 (52.56%), Query Frame = 0 
Query:   16 IYADAKFTGRYCNALALPNPDCGENITVNAIILDTFPNTKTHNTPTEQEVNLPVMDDLKVPIPQKDGKPSFF-----EAKQTITYDNK----LNKKYIRYLFDSKMGCGSISGFEIYYYKCPSATSSLAVFGVNNAPSLSDDAKEYEGKCVDNAVEVGNEKLTMKCAWNGTVQSITGQCVCLKGYEKENNQCKICDSQHFKPTQGNEKCTRCGLNSRSSIDKTT-CNCLHKYKREVIEINNPLAVCYKIPDVPSAISFSNITRNSVEITWSHPSQINKTN--IYIVDCNDCP------------SGVFPKTT--TDKFITINGLGAFADYEISVTFSSEVSRMIGENQTSKFESFKTLPGPPGKVRNLRQKSLDGGKVELSWDPPFAKGGNLITYLLTY--------GGSTKKTTLTTYIIESDAEDQTFTVKIAAQVSVGG-------QLLTGESSTFK----DKISVKGGVALDMAIGVGVGVVLLVIIIAIIAFYIYRKKHPPYAQAVRLENGQVELKTRFLSFPGSKLYVDPMTYGAVDEAVQEFAFELDQKSLTIGQLLGGGEFADVYKGTLFKNGKSK-EVAIKTLKQSATKHDRDDFLSEAAIVGQFTDPNVISLEGVVLKERPNVIVLEYMANGSLDKYLQKHDMQLTNLQLLGMARGVASGMKYLNELGFIHRDLAARNILVDEYRVCKVSDFGMSREIKVD--ETYDTQGGKIPVRWTAPESIQYKKFTTASDAWSYGILLWEIMSYGERPYWDWGNYEVLERLNQGYRLPPPMNCPKVIHDLMLHCWKKDRTKRPRMVEIRDQIEKWIRSPDLLETTVTVVTK-----TDENL-DYTVLQTINKWLDAIGMAKYTENFIEKGYATPRQILSLTLEDLEELGIAPIGHRKKIFKAIQNTKQQVEQRHNS 880
            I+ + KFT R CN+L      C E   +             +   T+ +    + ++L V I       SF      E K  +  + +    L+KK     F     C ++   ++YY KC S   +LA+F      S      E  G CV +A E       M C+  G      G+C+C  GY+++ + C+ C    +K +  + +C+RC  +S S  + ++ C C   Y R     + P   C + P  P  + F NI + +V + WS P+     N   Y + C  C              G  P+ T   D ++T+  L A A+Y   V   + VS +    +     S  T    P +V  + ++ +    VELSW  P    G +  Y + Y          ST KT  T+  I +      +  +I A  + G         + T E +T K      +S +    + +A+    G ++LV ++    F I R+ H  Y++A   + G  EL   F  FPG+K Y+DP TY   + AV +FA ELD   + I +++G GEF +V  G L   GK    VAIKTLK   T+  R DFL EA+I+GQF  PNV+ LEGVV + +P +IV+E+M NG+LD +L+KHD Q T +QL+GM RG+A+GM+YL ++G++HRDLAARNILV+   VCKVSDFG+SR I+ D    Y T GGKIPVRWTAPE+IQY+KFT+ASD WSYGI++WE+MSYGERPYWD  N +V++ + +GYRLP PM+CP  +H LML CW+K+R +RP+  +I   ++K IR+P+ L+T +   ++      D+N  D+T   ++ +WL AI M +Y +NF   GY +   +  +T+ED+  LGI  +GH+KKI  +IQ  + Q+   H +
Sbjct:   98 IFVELKFTLRDCNSLPGVLGTCKETFNL-------------YYYETDYDTGRNIRENLYVKIDTIAADESFTQGDLGERKMKLNTEVREIGPLSKKGFYLAFQDVGACIALVSVKVYYKKCWSIIENLAIFPDTVTGSEFSSLVEVRGTCVSSAEEEAENAPRMHCSAEGEWLVPIGKCICKAGYQQKGDTCEPCGRGFYKSSSQDLQCSRCPTHSFSDKEGSSRCECEDGYYRA--PSDPPYVACTRPPSAPQNLIF-NINQTTVSLEWSPPADNGGRNDVTYRILCKRCSWEQGECVPCGSNIGYMPQQTGLEDNYVTVMDLLAHANYTFEVEAVNGVSDLSRSQRLFAAVSITTGQAAPSQVSGVMKERVLQRSVELSWQEPEHPNGVITEYEIKYYEKDQRERTYSTVKTKSTSASINNLKPGTVYVFQIRAFTAAGYGNYSPRLDVATLEEATGKMFEATAVSSEQNPVIIIAVVAVAGTIILVFMV--FGFIIGRR-HCGYSKAD--QEGDEELYFHF-KFPGTKTYIDPETYEDPNRAVHQFAKELDASCIKIERVIGAGEFGEVCSGRLKLPGKRDVAVAIKTLKVGYTEKQRRDFLCEASIMGQFDHPNVVHLEGVVTRGKPVMIVIEFMENGALDAFLRKHDGQFTVIQLVGMLRGIAAGMRYLADMGYVHRDLAARNILVNSNLVCKVSDFGLSRVIEDDPEAVYTTTGGKIPVRWTAPEAIQYRKFTSASDVWSYGIVMWEVMSYGERPYWDMSNQDVIKAIEEGYRLPAPMDCPAGLHQLMLDCWQKERAERPKFEQIVGILDKMIRNPNSLKTPLGTCSRPISPLLDQNTPDFTTFCSVGEWLQAIKMERYKDNFTAAGYNSLESVARMTIEDVMSLGITLVGHQKKIMSSIQTMRAQMLHLHGT 994
The following BLAST results are available for this feature:
BLAST of TCONS_00022872-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
EPHA71.053e-16835.36Ephrin type-A receptor 7 OS=Homo sapiens GN=EPHA7 ... [more]
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