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Sequence
The following sequences are available for this feature:
polypeptide sequence >TCONS_00018061-protein ID=TCONS_00018061-protein|Name=TCONS_00018061-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1768bp
MVNKDTFEKTTKPQRKSSVPIVIPKNNGRKYNGFNSLQPDYEKSFTRKIT
PTRKISNPVDVPMIFDRKRSEINYDNDTNENSYDDEFISFDASHIQDNQT
KNTELTKNYTRNLIQRNRKTSVMFNSTRSTTHYSENVKKKKSSSGVSSSS
SDNNFPLHTHFTGHSETPFEDDRKFSDISIDELMSSTDSSPAVSRRSSSK
KLSDISREDLGYSSMKEKARVPKTSSTFNSNLNNKLGRQSTSKKIGLWTD
KINSQQKANNETSTIYSLRDKKKRTSKKESNAQDKINENNKSNESDGLDK
IKPARRRNTTITSDETERIEKIEPRPKVHRSISAKVSSFFGKKRSRDVTN
NSTGEEAIKKKISASVQPVEETVTEEKPKSQPPSRKTSQHLQLSSQQVTQ
LRRQSETNNRYKEEERKLSFVELHRKFSANTPAPQRRRTSAANTQLVDQS
TQTVDMATQTINNKLHYLQIVNNQHFNNTKSLSPSPPKERRRSLPMRMFG
STNYDFGEKFSPLEPNSTIPESELIDQRKSRSVICRCGNYTLECNDNKKH
DIGLNTIDDVNDDWGIAEENEDIDDEDDLDFGTSGPDSDFNTEISDTGLP
SWQRQAKLSYQKEEFGGVSSSEGNTDLSESEEPSSLPSWQKNALANDVRK
TSKPRRKFSYNPQPTQPIKKPLRRNKSHEINSINHPLSNAPWYQDETPVV
PNIRTTALSTSLSQDETETTSQSCSASEAVDDQPKVSVIHRPDLSQIALQ
RERSYYDDHNDGLDDFDKPTEKNYVNLKDLKNAPNIDLTSNLEAISLDPL
DPLEDQIRSRANTFDNNMPNEFRNMVPELPATLPRQRRRKTGIVHLHALD
SLPQRRRSVYQRDTSEISNSFDGVAEPSSSLSRKISTAFGGGFPHFMQDD
ANDSGPTRKMSTAFAAMPYPHLPEEVELVSDQNTLNVIVDSYDALNMDVD
IAGGTSGMASVQPFDNNNIHLLYRQQLDNLEEEEQDQEIMTPTAGTTPPF
SEDSYQNMSGFLEKRRRELLVKSDATREHASSPQTNRKFFGDQTDSVQST
PKVSVDETDSNTSQNGGGCSYTAYSTMFGYFNHFLYIFITKEYGNDKWTE
ITRSLKLTKEQKNMFKNAKHIMFDDEITDKVLNAAAKHLLVNFKLLLSKY
GMKYYEYCSEKYGGILKSIATNLTDFINNMDDIRKHIHKIEKIPDEFPPS
IHATNDKKTLSMYIQSSLGNKSLEYFMIGFIKRAALDLFGIRSRVSLKQE
RSDPKDYSIVEIKAITSLIKKPSLSKLQMSGKCKDLILEPDVMDRVFPFH
FILNDKFEITQLGDSLNRLLEQFIRNYGNHVQTYFQLDEPAIDFTYSMVR
KNLNTSFVVSLRREFVDSEVAENEIAGLVLKGQFSFLESSKSLWFIGSPK
VDYLKHFNGQSNLFLSDIPLHDVTREVLLVGEQKHSVETLKNQLQIMTNR
LKETSKELALGRINTESILDEMFPKDVADKLMRNQPVPTVTTESVTILFT
DIVGFTSICEQCDPEEVTVMLNKLYINFDLLCEKYQNYKVETIGDAYMAV
GGLHQSESEHGRYVTAMGVEMVQNAKKVKIPRKNENIQIRVGIHSGSVVA
GVVGTLMPRYCLFGKNVTLANKMESSSEAGKVHISPYTYLKIKHQQEFIF
WQRDRSCMPNLIDQSDPNIKYVNSFFVEQRRQSVIAPSKNITSKKSKTKQ
PYMQSQHFDAQSSRSRRTATSHRLSRTETAASMSDILSPNIPENLREQIE
ALDKINGDGKGLVFLNSS Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
This polypeptide derives from the following transcript feature(s):
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: Biological Process
| Term | Definition |
|---|
| GO:0009190 | cyclic nucleotide biosynthetic process |
| GO:0035556 | intracellular signal transduction |
| GO:0006182 | cGMP biosynthetic process |
Vocabulary: Molecular Function
| Term | Definition |
|---|
| GO:0016849 | phosphorus-oxygen lyase activity |
| GO:0020037 | heme binding |
| GO:0004383 | guanylate cyclase activity |
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
| Category |
Term Accession |
Term Name |
| biological_process |
GO:0006182 |
cGMP biosynthetic process |
| biological_process |
GO:0009190 |
cyclic nucleotide biosynthetic process |
| biological_process |
GO:0035556 |
intracellular signal transduction |
| molecular_function |
GO:0004383 |
guanylate cyclase activity |
| molecular_function |
GO:0020037 |
heme binding |
| molecular_function |
GO:0016849 |
phosphorus-oxygen lyase activity |
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
| IPR Term | IPR Description | Source | Source Term | Source Description | Alignment |
|---|
| None | No IPR available | COILS | Coil | Coil | coord: 1437..1457 |
| None | No IPR available | GENE3D | 3.90.1520.10 | | coord: 1077..1272
e-value: 2.1E-26
score: 92.2 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 709..735 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 1023..1066 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 1687..1734 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 255..416 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 185..241 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 570..672 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 114..171 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 428..449 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 982..1006 |
| None | No IPR available | CDD | cd07302 | CHD | coord: 1495..1655
e-value: 1.15201E-49
score: 175.46 |
| IPR001054 | Adenylyl cyclase class-3/4/guanylyl cyclase | SMART | SM00044 | cyc_6 | coord: 1460..1652
e-value: 9.7E-76
score: 267.6 |
| IPR001054 | Adenylyl cyclase class-3/4/guanylyl cyclase | GENE3D | 3.30.70.1230 | | coord: 1483..1664
e-value: 1.1E-55
score: 187.7 |
| IPR001054 | Adenylyl cyclase class-3/4/guanylyl cyclase | PFAM | PF00211 | Guanylate_cyc | coord: 1491..1658
e-value: 5.7E-55
score: 185.7 |
| IPR001054 | Adenylyl cyclase class-3/4/guanylyl cyclase | PROSITE | PS50125 | GUANYLATE_CYCLASE_2 | coord: 1496..1624
score: 43.281 |
| IPR011644 | Heme-NO binding | PFAM | PF07700 | HNOB | coord: 1084..1242
e-value: 3.5E-18
score: 66.0 |
| IPR011645 | Haem NO binding associated | PFAM | PF07701 | HNOBA | coord: 1288..1481
e-value: 2.3E-33
score: 115.4 |
| IPR018297 | Adenylyl cyclase class-4/guanylyl cyclase, conserved site | PROSITE | PS00452 | GUANYLATE_CYCLASE_1 | coord: 1601..1624 |
| IPR024096 | NO signalling/Golgi transport ligand-binding domain | SUPERFAMILY | 111126 | Ligand-binding domain in the NO signalling and Golgi transport | coord: 1077..1251 |
| IPR029787 | Nucleotide cyclase | SUPERFAMILY | 55073 | Nucleotide cyclase | coord: 1482..1655 |
Blast
BLAST of TCONS_00018061-protein vs. Swiss-Prot (Human)
Match: GCYB1 (Guanylate cyclase soluble subunit beta-1 OS=Homo sapiens GN=GUCY1B3 PE=1 SV=1) HSP 1 Score: 311.612 bits (797), Expect = 1.092e-91 Identity = 191/581 (32.87%), Postives = 319/581 (54.91%), Query Frame = 0
Query: 1077 MFGYFNHFLYIFITKEYGNDKWTEITRSLKLTKEQKNMFKNAKHIMFDDEITDKVLNAAAKHLLVNFKLLLSKYGMKYYEYCSEK-YGGILKSIATNLTDFINNMDDIRKHIHKIEKIPDEFPPSIHATNDKKTLSMYIQSSLGNKSLEYFMIGFIKRAALDLFGIRSRVSLKQERSDPKDYS--IVEIKAITSLIKKPSLSKLQMSGKCKDLILEPDVMDRVFPFHFILNDKFEITQLGDSLNRLLEQFIRNYGN-HVQTYFQLDEPAIDFTYSMVRKNLNTSFVVSLRREFVDSEVAE-------NEIAGLVLKGQFSFLESSKSLWFIGSPKVDYLKHFNGQSNLFLSDIPLHDVTREVLLVGEQKHSVETLKNQLQIMTNRLKETSKELALGRINTESILDEMFPKDVADKLMRNQPVPTVTTESVTILFTDIVGFTSICEQCDPEE----VTVMLNKLYINFDLLCEKYQN---YKVETIGDAYMAVGGLHQSESEHGRYVTAMGVEMVQNAKKVKIPRKNENIQIRVGIHSGSVVAGVVGTLMPRYCLFGKNVTLANKMESSSEAGKVHISPYTY 1639
M+G+ NH L + + + YG + W +I + +L +E + + + I++DD T ++ AA+K L +N +L +G ++ +C E Y IL+ + +N+ +F+ N+D + H+ I P PS T+ +K + + + L+ +IG IK A + G + + Q+R++ D++ ++E K L + + +G + I P + FPFH I + +TQ G+++ R+L Q GN + + F L P ID ++ + ++NT FV+ + +D E E EI+ L LKGQ +L + S+ F+ SP V L + L+LSDIPLHD TR+++L+GEQ L +L+I+T+RL+ T + L + T+++L + P VA++L +PVP ++VTILF+ IVGF + C + E + +LN LY FD L + +N YKVET+GD YM V GL + H R + + ++M++ A +V++ E++QI +GIH+G VV GV+G MPRYCLFG V L ++ E++ E GK+++S YTY
Sbjct: 1 MYGFVNHALELLVIRNYGPEVWEDIKKEAQLDEEGQFLVR----IIYDDSKTYDLVAAASKVLNLNAGEILQMFGKMFFVFCQESGYDTILRVLGSNVREFLQNLDALHDHLATI--YPGMRAPSFRCTDAEKGKGLILHYYSEREGLQDIVIGIIKTVAQQIHGTEIDMKVIQQRNEECDHTQFLIEEKESKEEDFYEDLDRFEENGTQESRI-SPYTFCKAFPFHIIFDRDLVVTQCGNAIYRVLPQL--QPGNCSLLSVFSLVRPHIDISFHGILSHINTVFVLRSKEGLLDVEKLECEDELTGTEISCLRLKGQMIYLPEADSILFLCSPSVMNLDDLT-RRGLYLSDIPLHDATRDLVLLGEQFREEYKLTQELEILTDRLQLTLRALEDEKKKTDTLLYSVLPPSVANELRHKRPVPAKRYDNVTILFSGIVGFNAFCSKHASGEGAMKIVNLLNDLYTRFDTLTDSRKNPFVYKVETVGDKYMTVSGLPEPCIHHARSICHLALDMMEIAGQVQV--DGESVQITIGIHTGEVVTGVIGQRMPRYCLFGNTVNLTSRTETTGEKGKINVSEYTY 569
The following BLAST results are available for this feature:
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