TCONS_00013710-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00013710-protein
Unique NameTCONS_00013710-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1025

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00013710-protein ID=TCONS_00013710-protein|Name=TCONS_00013710-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1025bp
MYTISSKLLPGRTIVRNTIRTLQSRHLASTQNRQQKNNRTSSNNRRYGTA
VGAEPFINGTSSSYVEEMYDSWKEDPTSVHKSWDIFFRNAENGAVPGQAY
QSPPEIYGHPVHYTTEVAVQPPASSASSAVQPSSDQVSSLIQNHLAVYSL
IRAYQLRGHNLADLDPLGILHADLDSRVPEELILENWGLSEKDLDKEFQL
PPTAFIGKSGEKLKLREIVNRLNNVYCKSMGLEYMFLTSLKKTNWIRKRF
EEQGVMEINAEEKRRLLARLIRSHEFESYLAKKWTSEKRFGLEGCEVLIP
ALKQIIDVSSTLGVESVIMGMPHRGRLNVLANVCRKPLEQLFTQFNPSLE
PEDEGSGDVKYHLGMTHERLNRTNNKIVQLAVCANPSHLEAVDPIVQGKT
RAEQFYRGDTKGRQVMSILLHGDAAFAGQGVVYETFHLSDLPHYTTHGTI
HVVVNNQVGFTTDPRMSRSSPYCTDVAKVVQCPIFHVNADDPEAVMHVCK
VASEYRAEFGKDVVIDLVCYRKNGHNEGDNPDFTQPLMYQRIRKQKPVME
KYAAKVIADGIVTDAEYQEERSKYDKILDESFENAKKRPEMKIADWLDSK
WGGFFKKHDLLGELKSTGASMDRLIDLGNKFSTPPANFNLHNGLKRVLKA
RKEMIDEGVADWAIGEALAFASLLTEKIHVRISGQDVERGTFSHRHHVLH
DQKVDQKYHSVMNHMSDDQAQYSVCNSSLSEYAVLGFELGYSMTNPYSLV
VWEAQFGDFMNTAQCIIDQFVGSGQDKWVRQSGLVMLLPHGMEGMGPEHS
SARPERFLQMTKEDPDTYPDYPADEFELRQNYNINWFICNISTPANFFHA
LRRQVYLDFRKPLVVMSPKSLLRDRRCRSSLDEMADGTFFKRVIPEEGVA
TQNGEQVKKLVFCTGKIYYDIRDKRDEQNLSSDIAVARIEQLSPFPFDLV
REECAKYPNASIQWVQEEHKNYGYWSHVQPRIETAAGDNRRAMYGGREVA
ASPATGVKKTHVEEHNAVLDSALAL
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_007655XLOC_007655Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00013710TCONS_00013710Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR005475Transketolase-like_Pyr-bd
IPR001017DH_E1
IPR0116032oxoglutarate_DH_E1
IPR031717KGD_C
IPR0321062-oxogl_dehyd_N
IPR029061THDP-binding
Vocabulary: Molecular Function
TermDefinition
GO:0016624oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
GO:0004591oxoglutarate dehydrogenase (succinyl-transferring) activity
GO:0030976thiamine pyrophosphate binding
Vocabulary: Biological Process
TermDefinition
GO:0008152metabolic process
GO:0006099tricarboxylic acid cycle
GO:0055114oxidation-reduction process
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0008152 metabolic process
biological_process GO:0055114 oxidation-reduction process
biological_process GO:0006099 tricarboxylic acid cycle
molecular_function GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
molecular_function GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity
molecular_function GO:0030976 thiamine pyrophosphate binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR005475Transketolase-like, pyrimidine-binding domainSMARTSM00861Transket_pyr_3coord: 660..874
e-value: 1.2E-46
score: 171.0
IPR005475Transketolase-like, pyrimidine-binding domainPFAMPF02779Transket_pyrcoord: 661..873
e-value: 9.7E-63
score: 210.9
IPR001017Dehydrogenase, E1 componentPFAMPF00676E1_dhcoord: 270..593
e-value: 2.0E-76
score: 256.8
IPR0116032-oxoglutarate dehydrogenase E1 componentPIRSFPIRSF000157Oxoglu_dh_E1coord: 42..1025
e-value: 0.0
score: 1191.4
IPR0116032-oxoglutarate dehydrogenase E1 componentTIGRFAMTIGR00239TIGR00239coord: 57..1022
e-value: 0.0
score: 1045.6
IPR031717Multifunctional 2-oxoglutarate metabolism enzyme, C-terminalPFAMPF16870OxoGdeHyase_Ccoord: 878..1023
e-value: 1.4E-50
score: 170.9
IPR0321062-oxoglutarate dehydrogenase E1 component, N-terminal domainPFAMPF160782-oxogl_dehyd_Ncoord: 55..93
e-value: 5.5E-19
score: 67.4
NoneNo IPR availableGENE3D1.10.287.1150coord: 137..228
e-value: 1.6E-24
score: 85.7
NoneNo IPR availableGENE3D3.40.50.970coord: 229..589
e-value: 6.1E-90
score: 301.2
NoneNo IPR availableGENE3D3.40.50.970coord: 660..890
e-value: 7.3E-57
score: 191.2
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 27..48
NoneNo IPR availableCDDcd02016TPP_E1_OGDC_likecoord: 276..539
e-value: 2.96082E-173
score: 508.607
IPR029061Thiamin diphosphate-binding foldSUPERFAMILY52518Thiamin diphosphate-binding fold (THDP-binding)coord: 645..880
IPR029061Thiamin diphosphate-binding foldSUPERFAMILY52518Thiamin diphosphate-binding fold (THDP-binding)coord: 186..604

Blast
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BLAST of TCONS_00013710-protein vs. Swiss-Prot (Human)
Match: ODO1 (2-oxoglutarate dehydrogenase, mitochondrial OS=Homo sapiens GN=OGDH PE=1 SV=3)

HSP 1 Score: 1278.08 bits (3306), Expect = 0.000e+0
Identity = 622/1036 (60.04%), Postives = 762/1036 (73.55%), Query Frame = 0 
Query:    1 MYTISSKLLPGRTIVRNTIRTLQSRHLASTQNRQQKNNRTSSNNRRYGTAVGAEPFINGTSSSYVEEMYDSWKEDPTSVHKSWDIFFRNAENGAVPGQAYQSPPEIYGHPVHYTTEVAVQPPASSASSAVQPSSDQVSSLIQNHLAVYSLIRAYQLRGHNLADLDPLGILHADLDSRVPEELI-----LENWGLSEKDLDKEFQLPPTAFIGKSGEKLKLREIVNRLNNVYCKSMGLEYMFLTSLKKTNWIRKRFEEQGVMEINAEEKRRLLARLIRSHEFESYLAKKWTSEKRFGLEGCEVLIPALKQIIDVSSTLGVESVIMGMPHRGRLNVLANVCRKPLEQLFTQFNPSLEPEDEGSGDVKYHLGMTHERLNRTNNKIVQLAVCANPSHLEAVDPIVQGKTRAEQFYRGDTKGRQVMSILLHGDAAFAGQGVVYETFHLSDLPHYTTHGTIHVVVNNQVGFTTDPRMSRSSPYCTDVAKVVQCPIFHVNADDPEAVMHVCKVASEYRAEFGKDVVIDLVCYRKNGHNEGDNPDFTQPLMYQRIRKQKPVMEKYAAKVIADGIVTDAEYQEERSKYDKILDESFENAKKRPEMKIADWLDSKWGGFFKKHDLLGELK-----STGASMDRLIDLGNKFSTPPA-NFNLHNGLKRVLKARKEMIDEGVADWAIGEALAFASLLTEKIHVRISGQDVERGTFSHRHHVLHDQKVDQKYHSVMNHMSDDQAQYSVCNSSLSEYAVLGFELGYSMTNPYSLVVWEAQFGDFMNTAQCIIDQFVGSGQDKWVRQSGLVMLLPHGMEGMGPEHSSARPERFLQMTKEDPDTYPDYPADEFELRQNYNINWFICNISTPANFFHALRRQVYLDFRKPLVVMSPKSLLRDRRCRSSLDEMADGTFFKRVIPEEGVATQNGEQVKKLVFCTGKIYYDIRDKRDEQNLSSDIAVARIEQLSPFPFDLVREECAKYPNASIQWVQEEHKNYGYWSHVQPRIETAAGDNRRAMYGGREVAASPATGVKKTHVEEHNAVLDSALAL 1025
            + T ++KL P       T++T        +QNR     RT    R Y   V AEPF++GTSS+YVEEMY +W E+P SVHKSWDIFFRN   GA PG AYQSP      P+   +  AV    + A S V+ +   V  L+++HLAV SLIRAYQ+RGH++A LDPLGIL ADLDS VP ++I     L  +GL E DLDK F LP T FIG     L LREI+ RL   YC+ +G+E+MF+  L++  WIR++FE  G+M+   EEKR LLARL+RS  FE +L +KW+SEKRFGLEGCEVLIPALK IID SS  GV+ VIMGMPHRGRLNVLANV RK LEQ+F QF+  LE  DEGSGDVKYHLGM H R+NR  ++ + L++ ANPSHLEA DP+V GKT+AEQFY GDT+G++VMSILLHGDAAFAGQG+VYETFHLSDLP YTTHGT+HVVVNNQ+GFTTDPRM+RSSPY TDVA+VV  PIFHVN+DDPEAVM+VCKVA+E+R+ F KDVV+DLVCYR+NGHNE D P FTQPLMY++IRKQKPV++KYA  +++ G+V   EY+EE SKYDKI +E+F  +K    + I  WLDS W GFF    L G+ +     STG + D L  +GN  S+ P  NF +H GL R+LK R EM+     DWA+ E +AF SLL E IH+R+SGQDVERGTFSHRHHVLHDQ VD++    MNH+  +QA Y+VCNSSLSEY VLGFELG++M +P +LV+WEAQFGDF NTAQCIIDQF+  GQ KWVRQ+G+V+LLPHGMEGMGPEHSSARPERFLQM  +DPD  PD     F++ Q Y+ NW + N STP NFFH LRRQ+ L FRKPL++ +PKSLLR    RSS DEM  GT F+RVIPE+G A QN E VK+L+FCTGK+YYD+  +R  +++   +A+ RIEQLSPFPFDL+ +E  KYPNA + W QEEHKN GY+ +V+PR+ T     +   Y GR+ AA+PATG KKTH+ E   +LD+A  L
Sbjct:    4 LRTCAAKLRP--LTASQTVKTF-------SQNRPAAA-RTFQQIRCYSAPVAAEPFLSGTSSNYVEEMYCAWLENPKSVHKSWDIFFRNTNAGAPPGTAYQSP-----LPLSRGSLAAV----AHAQSLVE-AQPNVDKLVEDHLAVQSLIRAYQIRGHHVAQLDPLGILDADLDSSVPADIISSTDKLGFYGLDESDLDKVFHLPTTTFIGGQESALPLREIIRRLEMAYCQHIGVEFMFINDLEQCQWIRQKFETPGIMQFTNEEKRTLLARLVRSTRFEEFLQRKWSSEKRFGLEGCEVLIPALKTIIDKSSENGVDYVIMGMPHRGRLNVLANVIRKELEQIFCQFDSKLEAADEGSGDVKYHLGMYHRRINRVTDRNITLSLVANPSHLEAADPVVMGKTKAEQFYCGDTEGKKVMSILLHGDAAFAGQGIVYETFHLSDLPSYTTHGTVHVVVNNQIGFTTDPRMARSSPYPTDVARVVNAPIFHVNSDDPEAVMYVCKVAAEWRSTFHKDVVVDLVCYRRNGHNEMDEPMFTQPLMYKQIRKQKPVLQKYAELLVSQGVVNQPEYEEEISKYDKICEEAFARSKDEKILHIKHWLDSPWPGFFT---LDGQPRSMSCPSTGLTEDILTHIGNVASSVPVENFTIHGGLSRILKTRGEMVKNRTVDWALAEYMAFGSLLKEGIHIRLSGQDVERGTFSHRHHVLHDQNVDKRTCIPMNHLWPNQAPYTVCNSSLSEYGVLGFELGFAMASPNALVLWEAQFGDFHNTAQCIIDQFICPGQAKWVRQNGIVLLLPHGMEGMGPEHSSARPERFLQMCNDDPDVLPDLKEANFDINQLYDCNWVVVNCSTPGNFFHVLRRQILLPFRKPLIIFTPKSLLRHPEARSSFDEMLPGTHFQRVIPEDGPAAQNPENVKRLLFCTGKVYYDLTRERKARDMVGQVAITRIEQLSPFPFDLLLKEVQKYPNAELAWCQEEHKNQGYYDYVKPRLRTTISRAKPVWYAGRDPAAAPATGNKKTHLTELQRLLDTAFDL 1016
The following BLAST results are available for this feature:
BLAST of TCONS_00013710-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
ODO10.000e+060.042-oxoglutarate dehydrogenase, mitochondrial OS=Hom... [more]
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