TCONS_00006337-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00006337-protein
Unique Name	TCONS_00006337-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	665

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00006337-protein ID=TCONS_00006337-protein|Name=TCONS_00006337-protein|organism=Clytia hemisphaerica|type=polypeptide|length=665bp
DKIKNIIFAIAMNEDEIKPRGLCGLSNIGNTCYMNSALQSLSNCPPLAQY
FMKSDEFLDFSKTDGKPLVSKCFKELLVQMWNKKRPKCITPSILLRAIRI
HNPAFRGNYQQDTQEFLRCLMDRLHEELKVPVVEIIKEQTGSSDEDISPR
NGKGLLGGNASADDSSNEMEISDTDGDVKAPLKKKRSRKRTLSTKSTPES
KAKNKKEEKAEVKKKEVTYRSIITNIFDGKLLSSVQCLTCNRISNRVETF
QDLSLPIPTFEDLKKIHTQAIISCSPNIYDDSNLINYMWTWVKSWFIGPN
IKLEDCLAAFFTHDELKGDNMYSCEKCKKLRNGIKYSRVHHLPEVLCIHL
KRFRHELYFSSKINTYISFPLCNLDMHNFLSKESIKTKQPSQYDLSAIIC
HFGSVGGGHYISYAKNCITNKWYEFNDAFVGEVNESVVVNAEAYVLFYSL
RDNRAEESRKDILNEINESPVDPLGIRYISKEWFTRYNACVKPGPVSNYE
LLCQHGAIDSQDFERVKDRVIPVPASAAHTLIKRFGGGPDISSLDECMHC
KELARRQDYELDTFNKLHERFQEEQDEVAVSYRISVRWFNTWRAFANAET
KEIPGEIDNSDIMPDENQGNKGDTYGQISGETWAFFHTRYGGGPVFRKEN
KIPEDSETEEMVVDG

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_003610	XLOC_003610	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00006337	TCONS_00006337	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR006615	Pept_C19_DUSP
IPR001394	Peptidase_C19_UCH
IPR018200	USP_CS
IPR028889	USP_dom

Vocabulary: **Molecular Function**
Term	Definition
GO:0004843	thiol-dependent ubiquitin-specific protease activity
GO:0036459	thiol-dependent ubiquitinyl hydrolase activity

Vocabulary: **Biological Process**
Term	Definition
GO:0016579	protein deubiquitination
GO:0006511	ubiquitin-dependent protein catabolic process

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0016579	protein deubiquitination
biological_process	GO:0006511	ubiquitin-dependent protein catabolic process
molecular_function	GO:0004843	thiol-dependent ubiquitin-specific protease activity
molecular_function	GO:0036459	thiol-dependent ubiquitinyl hydrolase activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR006615	Peptidase C19, ubiquitin-specific peptidase, DUSP domain	SMART	SM00695	dusp	coord: 574..653 e-value: 1.4E-6 score: 37.9 coord: 469..552 e-value: 4.3 score: 16.3
IPR006615	Peptidase C19, ubiquitin-specific peptidase, DUSP domain	GENE3D	3.30.2230.10		coord: 546..664 e-value: 4.2E-15 score: 55.1
IPR006615	Peptidase C19, ubiquitin-specific peptidase, DUSP domain	PFAM	PF06337	DUSP	coord: 582..645 e-value: 1.0E-7 score: 32.4
IPR006615	Peptidase C19, ubiquitin-specific peptidase, DUSP domain	PROSITE	PS51283	DUSP	coord: 555..652 score: 12.98
IPR006615	Peptidase C19, ubiquitin-specific peptidase, DUSP domain	PROSITE	PS51283	DUSP	coord: 453..547 score: 8.89
IPR006615	Peptidase C19, ubiquitin-specific peptidase, DUSP domain	SUPERFAMILY	143791	DUSP-like	coord: 558..646
IPR006615	Peptidase C19, ubiquitin-specific peptidase, DUSP domain	SUPERFAMILY	143791	DUSP-like	coord: 453..545
IPR001394	Peptidase C19, ubiquitin carboxyl-terminal hydrolase	PFAM	PF00443	UCH	coord: 23..448 e-value: 2.7E-63 score: 213.8
None	No IPR available	GENE3D	3.90.70.10		coord: 14..457 e-value: 9.0E-108 score: 359.4
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 139..210
None	No IPR available	SUPERFAMILY	54001	Cysteine proteinases	coord: 21..146 coord: 298..448 coord: 204..261
IPR018200	Ubiquitin specific protease, conserved site	PROSITE	PS00973	USP_2	coord: 393..410
IPR018200	Ubiquitin specific protease, conserved site	PROSITE	PS00972	USP_1	coord: 24..39
IPR028889	Ubiquitin specific protease domain	PROSITE	PS50235	USP_3	coord: 23..451 score: 55.51

Blast

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BLAST of TCONS_00006337-protein vs. Swiss-Prot (Human)
Match: UBP20 (Ubiquitin carboxyl-terminal hydrolase 20 OS=Homo sapiens GN=USP20 PE=1 SV=2)

HSP 1 Score: 429.098 bits (1102), Expect = 5.339e-139
Identity = 222/479 (46.35%), Postives = 302/479 (63.05%), Query Frame = 0

Query:  195 KSTPESKAKNKKEEKAEV------KKKEVTYRSIITNIFDGKLLSSVQCLTCNRISNRVETFQDLSLPIPTFEDLKKIHTQAI--ISCSPNIYDDSN--------LINYMWTWV----KSWFIGPNIKLEDCLAAFFTHDELKGDNMYSCEKCKKLRNGIKYSRVHHLPEVLCIHLKRFRHELYFSSKINTYISFPLCNLDMHNFLSKESIKTKQPSQYDLSAIICHFGSVGGGHYISYAKNCITNKWYEFNDAFVGEVNESVVVNAEAYVLFYSLRDNRAEESRKDILNEINESPVDPLGIR-YISKEWFTRYNACVKPGPVSNYELLCQHGAIDSQDFERVKDRVIPVPASAAHTLIKRFGGGPDISSLDECMHCK----ELARRQDYELDTFNKLHERFQEEQDEVAVSYRISVRWFNTWRAFANAETKEIPGEIDNSDIMPDENQGN----KGDTYGQISGETWAFFHTRYGGGP 644
            +++P   A +   +KA+V      ++KE  YRS+I++IFDG +LS VQCLTC+R+S  VETFQDLSLPIP  EDL K+H+     +   P    DS         ++ Y+  +V     SWF GP + LEDCLAAFF  DELKGDNMYSCE+CKKLRNG+KY +V  LPE+LCIHLKRFRHE+ +S KIN+++SFPL  LD+  FL+KE   T Q + YDL ++ICH G+ G GHYI+Y +N I  +WYEF+D +V EV+E+VV NAE YVLFY      A   R+ +++       +P  +R Y+S+EW  ++N   +PGP++N   LC HG I    +  + D V+ +P +    L  RFGGGP ++ L  C  C+     LA+R+  E+DTF KL++ FQ E+    V Y IS++WF  W AF   +  E PG IDNS I   +  G+    +G  YGQIS ETW + ++ YGGGP
Sbjct:  411 RASPVRMAPSYVLKKAQVLSAGSRRRKEQRYRSVISDIFDGSILSLVQCLTCDRVSTTVETFQDLSLPIPGKEDLAKLHSAIYQNVPAKPGACGDSYAAQGWLAFIVEYIRRFVVSCTPSWFWGPVVTLEDCLAAFFAADELKGDNMYSCERCKKLRNGVKYCKVLRLPEILCIHLKRFRHEVMYSFKINSHVSFPLEGLDLRPFLAKEC--TSQITTYDLLSVICHHGTAGSGHYIAYCQNVINGQWYEFDDQYVTEVHETVVQNAEGYVLFYRKSSEEAMRERQQVVSLAAMR--EPSLLRFYVSREWLNKFNTFAEPGPITNQTFLCSHGGIPPHKYHYIDDLVVILPQNVWEHLYNRFGGGPAVNHLYVCSICQVEIEALAKRRRIEIDTFIKLNKAFQAEESP-GVIYCISMQWFREWEAFVKGKDNEPPGPIDNSRIAQVKGSGHVQLKQGADYGQISEETWTYLNSLYGGGP 884

HSP 2 Score: 154.066 bits (388), Expect = 5.795e-39
Identity = 74/154 (48.05%), Postives = 105/154 (68.18%), Query Frame = 0

Query:    3 IKNIIFAIA------MNEDEIKPRGLCGLSNIGNTCYMNSALQSLSNCPPLAQYFMKSDEFLDFSKTDGKPLVSKCFKELLVQMWNKKRPKCITPSILLRAIRIHNPAFRGNYQQDTQEFLRCLMDRLHEELKVPVVEII----KEQTGSSDED 146
            +K +  A+A        +D++KPRGL G+ N+GN+CYMN+ALQ+LSNCPPL Q+F++    +   +TD KP + K +++L+ ++W+KKRP  + P+ L   I++ NP FRG  QQDTQEFLRCLMD+LHEELK PVV  +       + SSD D
Sbjct:  119 LKAVPIAVADEGESESEDDDLKPRGLTGMKNLGNSCYMNAALQALSNCPPLTQFFLECGGLV---RTDKKPALCKSYQKLVSEVWHKKRPSYVVPTSLSHGIKLVNPMFRGYAQQDTQEFLRCLMDQLHEELKEPVVATVALTEARDSDSSDTD 269

The following BLAST results are available for this feature:

BLAST of TCONS_00006337-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00006337-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
UBP20	5.339e-139	46.35	Ubiquitin carboxyl-terminal hydrolase 20 OS=Homo s...	[more]

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TCONS_00006337-protein (polypeptide) - C. hemisphaerica