TCONS_00071774-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00071774-protein
Unique Name	TCONS_00071774-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	493

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00071774-protein ID=TCONS_00071774-protein|Name=TCONS_00071774-protein|organism=Clytia hemisphaerica|type=polypeptide|length=493bp
MEKILHSKMKRLKILNMFFFALIIFGFAISFTNGNDGNRTRPMNETNTNS
SATRATATDIYDKLFGNDANYQAEIRPHATNGKRQLSISFDINIQTIGSL
DVKTQLFHVTSVIFMKWFDYRLTWNATEFNGIDTINVGNTIAWTPDIMLY
NDGSEEVVSHTDLHRSKVLIKDDGQLIWTNLVTNKATCQVDVTWFPMDEQ
VCNLTFGSWSYSKNVMDIKFKNKKKDSDMIKSGYHIPNGEWDIEKVEFFE
EEKSFDCCQQPFSVVTLQVSMVRYPDFYYLYVFLPFISQLILFLLIFHIH
PDQGDRLSYGVALLLNMTMYMIFLSDKLPEKSDKIPFVGTVFVAFFFLLS
IGLVLSAITMKYSKHETNLPKSAHKIKRLLNKISPTRTATLDLSNEGACF
PESFNLEEKNSSKITKNSSLIQDKDFINNIDRNGNSQNGLDHQTIESSTN
HDMDASNSFQGWYEYMRFVEKCLTFVFAVLMVLVPIIVAYCLK

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_044561	XLOC_044561	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00071774	TCONS_00071774	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR006201	Neur_channel
IPR006029	Neurotrans-gated_channel_TM
IPR006202	Neur_chan_lig-bd
IPR018000	Neurotransmitter_ion_chnl_CS

Vocabulary: **Cellular Component**
Term	Definition
GO:0016021	integral component of membrane

Vocabulary: **Biological Process**
Term	Definition
GO:0006811	ion transport

Vocabulary: **Molecular Function**
Term	Definition
GO:0005216	ion channel activity
GO:0005230	extracellular ligand-gated ion channel activity

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0006811	ion transport
cellular_component	GO:0016021	integral component of membrane
molecular_function	GO:0005230	extracellular ligand-gated ion channel activity
molecular_function	GO:0005216	ion channel activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR006201	Neurotransmitter-gated ion-channel	PRINTS	PR00252	NRIONCHANNEL	coord: 141..152 score: 42.68 coord: 108..124 score: 29.25 coord: 188..202 score: 49.83
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain	PFAM	PF02932	Neur_chan_memb	coord: 288..425 e-value: 8.4E-10 score: 39.0
IPR006029	Neurotransmitter-gated ion-channel transmembrane domain	SUPERFAMILY	90112	Neurotransmitter-gated ion-channel transmembrane pore	coord: 275..488
None	No IPR available	GENE3D	1.20.58.390		coord: 279..492 e-value: 8.1E-19 score: 67.2
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	GENE3D	2.70.170.10		coord: 52..278 e-value: 5.1E-53 score: 179.2
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	PFAM	PF02931	Neur_chan_LBD	coord: 58..273 e-value: 3.0E-49 score: 167.3
IPR006202	Neurotransmitter-gated ion-channel ligand-binding domain	SUPERFAMILY	63712	Nicotinic receptor ligand binding domain-like	coord: 57..273
IPR018000	Neurotransmitter-gated ion-channel, conserved site	PROSITE	PS00236	NEUROTR_ION_CHANNEL	coord: 188..202

Blast

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BLAST of TCONS_00071774-protein vs. Swiss-Prot (Human)
Match: ACHA7 (Neuronal acetylcholine receptor subunit alpha-7 OS=Homo sapiens GN=CHRNA7 PE=1 SV=5)

HSP 1 Score: 187.193 bits (474), Expect = 2.764e-53
Identity = 102/317 (32.18%), Postives = 175/317 (55.21%), Query Frame = 0

Query:   70 NYQAEIRPHATNGKRQLSISFDINIQTIGSLDVKTQLFHVTSVIFMKWFDYRLTWNATEFNGIDTINVGNTIAWTPDIMLYNDGSE--EVVSHTDLHRSKVLIKDDGQLIWTNLVTNKATCQVDVTWFPMDEQVCNLTFGSWSYSKNVMDIKFKNKKKDSDMIKSGYHIPNGEWDIEKVEFFEEEKSFDCCQQPFSVVTLQVSMVRYPDFYYLYVFLPFISQLILFLLIFHIHPDQGDRLSYGVALLLNMTMYMIFLSDKLPEKSDKIPFVGTVFVAFFFLLSIGLVLSAITMKYSKHETN---LPKSAHKIKRLLN 381
            NY    RP A N  + L++ F +++  I  +D K Q+      + M W D+ L WN +E+ G+ T+   +   W PDI+LYN   E  +   HT+     VL+   G   +      K++C +DV WFP D Q C L FGSWSY    +D++ +    ++D+  SGY IPNGEWD+  +     E+ ++CC++P+  VT  V+M R   +Y L + +P +    L LL+F +  D G+++S G+ +LL++T++M+ +++ +P  SD +P +   F +   ++ + +V++ I ++Y  H+ +   +PK    I  LLN
Sbjct:   36 NYNPLERPVA-NDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEYPGVKTVRFPDGQIWKPDILLYNSADERFDATFHTN-----VLVNSSGHCQYLPPGIFKSSCYIDVRWFPFDVQHCKLKFGSWSYGGWSLDLQMQ----EADI--SGY-IPNGEWDLVGIPGKRSERFYECCKEPYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADSGEKISLGITVLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIVGLSVVVTVIVLQYHHHDPDGGKMPKWTRVI--LLN 337

The following BLAST results are available for this feature:

BLAST of TCONS_00071774-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00071774-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
ACHA7	2.764e-53	32.18	Neuronal acetylcholine receptor subunit alpha-7 OS...	[more]

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TCONS_00071774-protein (polypeptide) - C. hemisphaerica