TCONS_00068142-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00068142-protein
Unique NameTCONS_00068142-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1546

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00068142-protein ID=TCONS_00068142-protein|Name=TCONS_00068142-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1546bp
MMQTCCSHILFLVLGVILSTPWSKIANADDGGTGNNGVVPYKPCFLNQPQ
VNIRLSTNGHCLTPKTCNELKGCTVLHGSLILRRIIQYKVVNTTVPDLSS
LQEITGYLVITFFAEVADLLPSLTVIRGNDLVGNYAFVVYFNTYTKFIYF
PNLTTILNGGVRVSMNKILCYVGTVRWKSIVKDKEQKSKYGIVVTDNNDN
CDSACYPNRCYAGKGHGNNPKAQFCWGPGTEKNTQCQRFCDSRCDLQGCV
TGTSSKCCHSLCLGGCSKADDPYACSACLKYRVWSTGLCVNQCPVNTYLV
DNLFCKPQCPGWSAEDQKNKIVHHFVMDSKCVEQCPAGYIAKDKTCQECS
RVDSCPKVCILKEERLENGLMDRIAYIRVPSDIVNKGLAGCTEIIGSLSF
EIPKGTGKSEEYLKNLELLRKVRGHISIKKTSFRNLNFLSNLEIIDPPRH
NLLYRRYALQIYENELLETLWAPSKKINVTNGQIFAQYNDRLCPREIFKV
QKLMHTSKGENVTGDISTQTNGNRVFCDVERLEISVEEIHIPQHIVDKLT
KVDPNEVLPFLSWSNPDFIKYLDYLQCLTDKCMLVQWQFKRDQRSSYNII
FYQVFYRKLKEDEKETEEVVTADVENNLEWKNIFVERPTDFAKTSTMEPM
LNNLTPFARYAVFVREVVSKGEARTSRIHYLRISPGIPTAPVGLEASFLS
SESIHLKWNQPDQPNGIVNKYIIYWQPSIYSFWKEHSYIEWCKRDNVKSG
VVHQSNFGNKKPPIPKGENEGQCLANNTCVCSDKDKPTSEAIKWDRDNSA
FRAEFGERINKILFTKERSDDEDDNNNNNINETEIFNASVDNLSRQSTNK
SLSELEKYNNQLRQGKVNLKNVEVTGDIFNFTVNGLQYFQDYEFHVCACT
EQINISGIIYGGCAKPKTDPNDVGYPCAIAQARTDAKSGADALGSALRLA
VEDQLFNITWLPPVKPNAVVLKYDVEIKHEDRNNDIIHCRSARDTSFSRT
MQPGTYYIRARAQTPAGNGSWSEAVELIIEQPEVDNPLILPLGVGISVLF
VILVILIVYYAFFRRNLEKDSPGVLYASVNPEYMNSNEVYVPDEWELNRE
TIELLRELGQGSFGMVYEGIAHDINGLSELRVAVKTVNENATIRERIEFL
QEASIMKAFNTNHVVRLIGVVSQGQPTFVVMELMAKGDLKNFLRSRRPEE
KNPTLLPPLRAEILQMAAEIADGMAYLAARKYVHRDLAARNCMVAVDFTV
KIGDFGMARDIYETDYYRKGGKGLLPVRWMAPESLRDGIFTTASDVWSFG
VVLWEVATLAAQPYQGKSNEEVLKFILAGGKLEYPSDCDKRLQQFMEMCW
SKDPKMRPSFLEIVRLLEDDVSEDFVQCSFYHEMKKKALEDTLCQEGNLY
ELLARPLNTPLTNSGGKLKRDHSTCSSDDSGAFIESCKNDADQTPTLERH
DSFHAPLPRHPTKEAAETSTPLPPNRNSLIAQRQNSAPHHYDNINDQMRY
GASPVAPPICPGGERPSTTSGPDAFKESREELKLSKIFGIGKGVPV
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_042535XLOC_042535Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00068142TCONS_00068142Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001245Ser-Thr/Tyr_kinase_cat_dom
IPR003961FN3_dom
IPR006212Furin_repeat
IPR020635Tyr_kinase_cat_dom
IPR013783Ig-like_fold
IPR000494Rcpt_L-dom
IPR006211Furin-like_Cys-rich_dom
IPR017441Protein_kinase_ATP_BS
IPR002011Tyr_kinase_rcpt_2_CS
IPR008266Tyr_kinase_AS
IPR000719Prot_kinase_dom
IPR032675L_dom-like
IPR011009Kinase-like_dom
IPR009030Growth_fac_rcpt_
Vocabulary: Molecular Function
TermDefinition
GO:0004672protein kinase activity
GO:0005515protein binding
GO:0004713protein tyrosine kinase activity
GO:0004714transmembrane receptor protein tyrosine kinase activity
GO:0005524ATP binding
Vocabulary: Biological Process
TermDefinition
GO:0006468protein phosphorylation
GO:0007169transmembrane receptor protein tyrosine kinase signaling pathway
Vocabulary: Cellular Component
TermDefinition
GO:0016020membrane
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006468 protein phosphorylation
biological_process GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
cellular_component GO:0016020 membrane
molecular_function GO:0005524 ATP binding
molecular_function GO:0005515 protein binding
molecular_function GO:0004672 protein kinase activity
molecular_function GO:0004713 protein tyrosine kinase activity
molecular_function GO:0004714 transmembrane receptor protein tyrosine kinase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 855..875
NoneNo IPR availableGENE3D1.10.510.10coord: 1185..1482
e-value: 6.2E-50
score: 169.3
NoneNo IPR availableGENE3D3.30.200.20coord: 1083..1184
e-value: 1.2E-22
score: 79.4
NoneNo IPR availableGENE3D2.10.220.10coord: 253..350
e-value: 1.5E-5
score: 24.6
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1443..1474
NoneNo IPR availableCDDcd05032PTKc_InsR_likecoord: 1095..1369
e-value: 2.09354E-178
score: 535.771
NoneNo IPR availableCDDcd00064FUcoord: 257..302
e-value: 9.94636E-5
score: 40.9652
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPRINTSPR00109TYRKINASEcoord: 1181..1194
score: 50.37
coord: 1275..1285
score: 63.14
coord: 1294..1316
score: 60.14
coord: 1226..1244
score: 63.43
coord: 1338..1360
score: 41.21
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPFAMPF07714Pkinase_Tyrcoord: 1102..1367
e-value: 3.4E-92
score: 308.3
IPR003961Fibronectin type IIISMARTSM00060FN3_2coord: 943..1019
e-value: 26.0
score: 7.9
coord: 566..673
e-value: 130.0
score: 1.9
coord: 688..906
e-value: 1.0E-7
score: 41.7
IPR003961Fibronectin type IIIPROSITEPS50853FN3coord: 690..788
score: 7.985
IPR003961Fibronectin type IIIPROSITEPS50853FN3coord: 942..1032
score: 11.409
IPR003961Fibronectin type IIIPROSITEPS50853FN3coord: 565..686
score: 7.117
IPR003961Fibronectin type IIICDDcd00063FN3coord: 688..735
e-value: 4.40901E-7
score: 48.6467
IPR003961Fibronectin type IIICDDcd00063FN3coord: 956..1028
e-value: 8.06308E-6
score: 44.7947
IPR003961Fibronectin type IIISUPERFAMILY49265Fibronectin type IIIcoord: 951..1028
IPR003961Fibronectin type IIISUPERFAMILY49265Fibronectin type IIIcoord: 577..614
coord: 644..726
coord: 873..901
IPR006212Furin-like repeatSMARTSM00261furin_3coord: 254..299
e-value: 1.3E-4
score: 31.4
IPR020635Tyrosine-protein kinase, catalytic domainSMARTSM00219tyrkin_6coord: 1102..1367
e-value: 2.8E-135
score: 465.4
IPR013783Immunoglobulin-like foldGENE3D2.60.40.10coord: 686..921
e-value: 1.3E-15
score: 56.9
IPR013783Immunoglobulin-like foldGENE3D2.60.40.10coord: 579..680
e-value: 3.6E-5
score: 23.6
IPR013783Immunoglobulin-like foldGENE3D2.60.40.10coord: 932..1033
e-value: 3.0E-9
score: 36.4
IPR000494Receptor L-domainGENE3D3.80.20.20coord: 351..578
e-value: 5.1E-21
score: 74.8
IPR000494Receptor L-domainPFAMPF01030Recep_L_domaincoord: 72..180
e-value: 2.1E-18
score: 66.4
coord: 390..498
e-value: 4.5E-19
score: 68.5
IPR000494Receptor L-domainGENE3D3.80.20.20coord: 55..252
e-value: 7.8E-32
score: 110.2
IPR006211Furin-like cysteine-rich domainPFAMPF00757Furin-likecoord: 214..359
e-value: 3.0E-18
score: 66.0
IPR017441Protein kinase, ATP binding sitePROSITEPS00107PROTEIN_KINASE_ATPcoord: 1108..1135
IPR002011Tyrosine-protein kinase, receptor class II, conserved sitePROSITEPS00239RECEPTOR_TYR_KIN_IIcoord: 1260..1268
IPR008266Tyrosine-protein kinase, active sitePROSITEPS00109PROTEIN_KINASE_TYRcoord: 1232..1244
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 1102..1376
score: 38.237
IPR032675Leucine-rich repeat domain, L domain-likeSUPERFAMILY52058L domain-likecoord: 65..227
IPR032675Leucine-rich repeat domain, L domain-likeSUPERFAMILY52058L domain-likecoord: 387..528
IPR011009Protein kinase-like domainSUPERFAMILY56112Protein kinase-like (PK-like)coord: 1075..1367
IPR009030Growth factor receptor cysteine-rich domainSUPERFAMILY57184Growth factor receptor domaincoord: 258..359

Blast
[Close]
BLAST of TCONS_00068142-protein vs. Swiss-Prot (Human)
Match: INSR (Insulin receptor OS=Homo sapiens GN=INSR PE=1 SV=4)

HSP 1 Score: 736.487 bits (1900), Expect = 0.000e+0
Identity = 495/1383 (35.79%), Postives = 719/1383 (51.99%), Query Frame = 0 
Query:   68 NELKGCTVLHGSLILRRIIQYKVVNTTVPDLS--SLQEITGYLV---ITFFAEVADLLPSLTVIRGNDLVGNYAFVVYFNTYTKFIYFPNLTTILNGGVRVSMNKILCYVGTVRWKSIVKDKEQKSKYGIVVTDNNDNCDSACYPNRCYAGKGHGNNP----KAQF---CWGPGTEKNTQCQRFCDSRCDLQGCVTGTSSKCCHSLCLGGCSKADDPYACSACLKYRVWSTGLCVNQCPVNTY------LVDNLFCKPQCPGWSAEDQKNKIVHHFVM-DSKCVEQCPAGYI--AKDKTCQECSRVDSCPKVCILKEERLENGLMDRIAYIRVPSDIVNKGLAGCTEIIGSLSFEIPKGTGKSEEYLKNLELLRKVRGHISIKKT-SFRNLNFLSNLEIIDPPRHNLLYRRYALQIYENELLETLWAPSKK-INVTNGQIFAQYNDRLCPREIFKVQKLMHTSKGENVTGDISTQTNGNRVFCDVERLEISVEEIHIPQHIVDKLTKVDPNEVLPFLSWSNPDFIKYLDYLQCLTDKCMLVQWQ--FKRDQRSSYNIIFYQVFYRKLKEDEKETEEVVTADVENNLEWKNIFVERP---TDFAKTSTMEPMLNNLTPFARYAVFVREVVSKGEAR-----TSRIHYLRISPGIPTAPVGLEASFLSSESIHLKWNQPDQPNGIVNKYIIYWQPSIYSFWKEHSYIEWCKRDNVKSGVVHQSNFGNKKPPIPK------GENEGQCLANNTCVCSDKDKPTSEAIKWDRDNSAFRAEFGERINKILFTKERS-------DDEDDNNNNNINETEIFNASVDNLSRQSTNKSLSELEKYNNQLRQGKVNLKNVEVTGDIFNFTVNGLQYFQDYEFHVCACTEQINISGIIYGGCAKPKTDPNDVGYPCAIAQARTDAKSGADAL-GSALRLAVEDQLFNITWLPPVKPNAVVLKYDVEIKHEDRNNDIIH-CRSARDTSFSRT-----MQPGTYYIRARAQTPAGNGSWSEAVELIIEQPEVDNPL-ILPLGVGISVLFVILVILIVYYAFFRRNLEKDSP-GVLYASVNPEYMNSNEV-----YVPDEWELNRETIELLRELGQGSFGMVYEGIAHDI-NGLSELRVAVKTVNENATIRERIEFLQEASIMKAFNTNHVVRLIGVVSQGQPTFVVMELMAKGDLKNFLRSRRPE-EKNPTLLPPLRAEILQMAAEIADGMAYLAARKYVHRDLAARNCMVAVDFTVKIGDFGMARDIYETDYYRKGGKGLLPVRWMAPESLRDGIFTTASDVWSFGVVLWEVATLAAQPYQGKSNEEVLKFILAGGKLEYPSDCDKRLQQFMEMCWSKDPKMRPSFLEIVRLLEDDVSEDFVQCSFYHEMKKKA 1388
            +EL+ C+V+ G L +  ++ +K       DLS   L  IT YL+   +     + DL P+LTVIRG+ L  NYA V++   + K +   NL  I  G VR+  N  LCY+ T+ W  I+   E    Y ++  D+N+ C   C P      KG  N P      QF   CW      ++ CQ+ C + C   GC       CCHS CLG CS+ DDP  C AC  +  +  G CV  CP   Y       V+  FC  Q      ++ + +  H +V+ ++KC+ +CP+GY   + +  C  C  +  CPKVC L E               + S    + L GCT I GSL   I  G   + E   NL L+ ++ G++ I+++ +  +L+F   L +I      L    Y+    +N+ L  LW  SK  + +T G++F  YN +LC  EI K++++  T KG     DI+ +TNG++  C+                          NE+L F             Y++   DK +L++W+  +  D R   +++ + +FY++     +   E    D   +  W  + ++ P    D    +    ++  L P+ +YA+FV+ +V+  + R      S I Y++     P+ P+   +   SS  I LKW  P  PNG +  Y+++W+       ++    E  + D    G+   S      PP          ++E +  A   C C   D   S+ +K + + S+FR  F + ++ ++F   ++       D        ++ +      +V  ++      S S            KV  K         +  ++GL++F  Y   + AC +                  P +     A   ART  ++ AD + G       E+ + ++ W  P +PN +++ Y  E+ +    ++ +H C S +  +  R      + PG Y +R RA + AGNGSW+E     +    +D P  I  + +G  +   +  ++I     F R  + D P G LYAS NPEY+++++V     YVPDEWE++RE I LLRELGQGSFGMVYEG A DI  G +E RVAVKTVNE+A++RERIEFL EAS+MK F  +HVVRL+GVVS+GQPT VVMELMA GDLK++LRS RPE E NP   PP   E++QMAAEIADGMAYL A+K+VHRDLAARNCMVA DFTVKIGDFGM RDIYETDYYRKGGKGLLPVRWMAPESL+DG+FTT+SD+WSFGVVLWE+ +LA QPYQG SNE+VLKF++ GG L+ P +C +R+   M MCW  +PKMRP+FLEIV LL+DD+   F + SF+H  + KA
Sbjct:   48 HELENCSVIEGHLQI--LLMFKTRPEDFRDLSFPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYALVIFEMVHLKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDN--YIVLNKDDNEECGDIC-PG---TAKGKTNCPATVINGQFVERCW-----THSHCQKVCPTICKSHGCTA--EGLCCHSECLGNCSQPDDPTKCVACRNF--YLDGRCVETCPPPYYHFQDWRCVNFSFC--QDLHHKCKNSRRQGCHQYVIHNNKCIPECPSGYTMNSSNLLCTPC--LGPCPKVCHLLE-----------GEKTIDSVTSAQELRGCTVINGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIR--GETLEIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGT-KGRQERNDIALKTNGDQASCE--------------------------NELLKF------------SYIRTSFDK-ILLRWEPYWPPDFR---DLLGFMLFYKEAPY--QNVTEFDGQDACGSNSWTVVDIDPPLRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFSDERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWE-------RQAEDSELFELDYCLKGLKLPSR--TWSPPFESEDSQKHNQSEYEDSAGECCSCPKTD---SQILK-ELEESSFRKTFEDYLHNVVFVPRKTSSGTGAEDPRPSRKRRSLGDVGNVTVAVPTVAAFPNTSSTSVPTSPEEHRPFEKVVNKE--------SLVISGLRHFTGYRIELQACNQDT----------------PEERCSVAAYVSARTMPEAKADDIVGPVTHEIFENNVVHLMWQEPKEPNGLIVLY--EVSYRRYGDEELHLCVSRKHFALERGCRLRGLSPGNYSVRIRATSLAGNGSWTEPTYFYVTD-YLDVPSNIAKIIIGPLIFVFLFSVVIGSIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVSREKITLLRELGQGSFGMVYEGNARDIIKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVRLLGVVSKGQPTLVVMELMAHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAAEIADGMAYLNAKKFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGVFTTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNCPERVTDLMRMCWQFNPKMRPTFLEIVNLLKDDLHPSFPEVSFFHSEENKA 1311
The following BLAST results are available for this feature:
BLAST of TCONS_00068142-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
INSR0.000e+035.79Insulin receptor OS=Homo sapiens GN=INSR PE=1 SV=4[more]
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