TCONS_00067135-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00067135-protein
Unique Name	TCONS_00067135-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	885

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00067135-protein ID=TCONS_00067135-protein|Name=TCONS_00067135-protein|organism=Clytia hemisphaerica|type=polypeptide|length=885bp
MGCTPSIHVSQRTGVVYCRDDIKDSSGGSSGLQPTHVSKRLSAASLSISE
VVSHIPSVHRESLTTEVRITHYQTGGKRDSLITTTTTTTQAWVSAEGKHT
QTDPIFKEMDKATKCELELGPMKVYKHPMEILLVFGCKDKQSDALENAAK
KGSYRCRLATTAESAMEYYLKKLPELVIIDLRSNQYFDGETLCRNIRGTR
PIVNTVIVGVTKRPEGEDVSILPLIKAGFDRRFVEDYSVTACFNELLMLD
NGEVSSQCKLKATSCLFSAVEHAYDAIEIQCVDTEKTEFQYVNPAYEKVT
GFWRSEIVGNQKNNILSNCEVPTPESHDNISKQLSRGKSWEGVCIARKKS
GEQFVQSLKIVPIIGHAGRVTHYVVVKRDLTAVERDSQIQQMHQELQKIR
VDSKGTDKNQIANNNTGLTVANYVPIRAEAPITKVINMLNAVQDNSPNGV
VQVLDRVIDILRTTELYTPSSLDQVEDKTREGRDLVEGLMMNKMERRLSA
DSHVKGHSSANSMITKVSQPMKAPPDIQLALEGDDKWSFDIIKLEKVTQK
RPLYYLGQKIFTRFDVAGYLSVPDIVIRNWLELIEDNYSSHNTYHNSTHA
ADVLHATAVFLLQDDVKNVLERSDEVASLIAAVVHDVDHPGFTNSFLCNA
GSELAVLYNDLAVLESHHAAMAFKLTCRDSNSNIFKNLKQDDFKMIRQSI
IDMVMATEMKQHFEHLAKFENNFNKRHNAHEDGQSTNGRGTPESVSSALT
NFQSPENRAIVRRMIIKCADIANPARPTELCKVWAYRIAEEYFRQTEEEK
KRGLPIVMPVFDRHTCNVPKSQIFFIDYFVMNLYVSWNKFAQVSKAMEYL
NKNYEYWTSEADQLEKDKDKETSNDEPSSTVTSSS

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_041947	XLOC_041947	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00067135	TCONS_00067135	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR023088	PDEase
IPR003607	HD/PDEase_dom
IPR013938	PDEase_PDE8
IPR002073	PDEase_catalytic_dom
IPR000014	PAS
IPR023174	PDEase_CS
IPR011006	CheY-like_superfamily

Vocabulary: **Molecular Function**
Term	Definition
GO:0008081	phosphoric diester hydrolase activity
GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity

Vocabulary: **Biological Process**
Term	Definition
GO:0007165	signal transduction

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0007165	signal transduction
molecular_function	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity
molecular_function	GO:0008081	phosphoric diester hydrolase activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR023088	3'5'-cyclic nucleotide phosphodiesterase	PRINTS	PR00387	PDIESTERASE1	coord: 590..603 score: 52.71 coord: 662..678 score: 37.88 coord: 635..650 score: 50.38
IPR003607	HD/PDEase domain	SMART	SM00471	hd_13	coord: 592..784 e-value: 0.0026 score: 27.0
IPR013938	3'5'-cyclic nucleotide phosphodiesterase PDE8	PFAM	PF08629	PDE8	coord: 1..43 e-value: 4.5E-8 score: 32.9
IPR002073	3'5'-cyclic nucleotide phosphodiesterase, catalytic domain	GENE3D	1.10.1300.10		coord: 515..884 e-value: 6.5E-112 score: 373.6
IPR002073	3'5'-cyclic nucleotide phosphodiesterase, catalytic domain	PFAM	PF00233	PDEase_I	coord: 594..848 e-value: 3.9E-83 score: 278.7
None	No IPR available	GENE3D	3.30.450.20		coord: 266..419 e-value: 1.1E-11 score: 44.4
None	No IPR available	GENE3D	3.40.50.2300		coord: 121..241 e-value: 5.7E-6 score: 25.6
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 864..885
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 727..749
None	No IPR available	CDD	cd00077	HDc	coord: 594..793 e-value: 5.60864E-8 score: 50.8009
None	No IPR available	SUPERFAMILY	109604	HD-domain/PDEase-like	coord: 531..877
IPR000014	PAS domain	TIGRFAM	TIGR00229	TIGR00229	coord: 281..383 e-value: 2.6E-8 score: 32.0
IPR000014	PAS domain	PFAM	PF13426	PAS_9	coord: 282..381 e-value: 2.1E-9 score: 37.4
IPR000014	PAS domain	PROSITE	PS50112	PAS	coord: 282..336 score: 8.719
IPR000014	PAS domain	CDD	cd00130	PAS	coord: 281..380 e-value: 2.48913E-5 score: 42.2351
IPR000014	PAS domain	SUPERFAMILY	55785	PYP-like sensor domain (PAS domain)	coord: 286..381
IPR023174	3'5'-cyclic nucleotide phosphodiesterase, conserved site	PROSITE	PS00126	PDEASE_I	coord: 635..646
IPR011006	CheY-like superfamily	SUPERFAMILY	52172	CheY-like	coord: 149..219

Blast

[Close]

BLAST of TCONS_00067135-protein vs. Swiss-Prot (Human)
Match: PDE8B (High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B OS=Homo sapiens GN=PDE8B PE=1 SV=2)

HSP 1 Score: 726.857 bits (1875), Expect = 0.000e+0
Identity = 387/897 (43.14%), Postives = 562/897 (62.65%), Query Frame = 0

Query:    1 MGCTPSIHVSQRTGVVYCRDDIKDSSGGSSGLQPTHVSKRLSAASLSI---SEVVSHIPSVHRESLTTEVRITHYQT-------GGKRDSLITTTTTTTQAWVSAEGKHTQTDPIFKEMDKATKCELELGPMKVYKHPMEILLVFGCKDKQSDALENAAKKGSYRCRLATTAESAMEYYLKKLPELVIIDLRSNQYFDGETLCRNIRGTRPIVNTVIVGVTKR--PEGEDVSILPLIKAGFDRRFVEDYSVTACFNELLMLDNGEVSSQCKLKATSCLFSAVEHAYDAIEIQCVDTEKTEFQYVNPAYEKVTGFWRSEIVGNQKNNILSNCEVPTPESHDNISKQLSRGKSWEGVCIARKKSGEQFVQSLKIVPIIGHAGRVTHYVVVKRDLTAVERDSQIQQMHQ--------ELQKIR-------------VDSKGTDKNQIANNNTGLTVANYVPIRAEAPITKVINMLNAVQDNSPNGVVQVLDRVIDILRTTELYTPSSLDQVEDKTREGRDLVEGLMMNKMERRLSADSHV--KGHSSANSMITKVSQPMKAPPDIQLALEGDDKWSFDIIKLEKVTQKRPLYYLGQKIFTRFDVAGYLSVPDIVIRNWLELIEDNYSSHNTYHNSTHAADVLHATAVFLLQDDVKNVLERSDEVASLIAAVVHDVDHPGFTNSFLCNAGSELAVLYNDLAVLESHHAAMAFKLTCRDSNSNIFKNLKQDDFKMIRQSIIDMVMATEMKQHFEHLAKFENNFNKRHNAHEDGQSTNGRGTPESVSSALTNFQSPENRAIVRRMIIKCADIANPARPTELCKVWAYRIAEEYFRQTEEEKKRGLPIVMPVFDRHTCNVPKSQIFFIDYFVMNLYVSWNKFAQVSKAMEYLNKNYEYWTSEAD 862
            MGC PSIHVSQ +GV+YCRD    S   SS  Q T VS+  +A    +   ++    IP        +  R+   +T        G      TT+    +   S+    TQT   +  + + +  E+ +GPM++ + P+++LL+F  +D QSD    A  +  YRC +A T ESA+E +L K  E+++ID R  Q FD E +CR+IR T P  +TVI+ V  R   + E+ S+LPL+ AGF+RRF+E+ S+ AC+NEL+ +++GEV SQ KL+A + +F+A++H ++AIEI    ++    QYVNPA+E++ G+ + E++G +  + L   +    +  D I+  + +GK W+GV  AR+KSG+   Q +KI P+IG  G++ H+V +K+     + + QI ++H+        E    R             + S+G+D   + N     ++A    +  EAPITKVIN++NA Q+NSP  V + LDRV++ILRTTELY+P    + ED      DLV GLM + + RRLS + +V  K    ++S +         PP I   L+ ++ W F+I +LE +T KRPL YLG K+F+RF V  +L+  +  +R W ++IE NY S N YHNSTHAADVLHATA FL ++ VK  L++ DEVA+LIAA VHDVDHPG TNSFLCNAGSELAVLYND AVLESHH A+AF+LT +D+  NIFKN+ ++ ++ +RQ+IIDMV+ATEM +HFEH+ KF N+ NK   A  +G            + A  NF  PEN+ +++RM+IKCAD+ANP RP +LC  WA RI+EEYF QT+EEK++GLP+VMPVFDR+TC++PKSQI FIDYF+ +++ +W+ FA +   M++L  NY++W +  D
Sbjct:    1 MGCAPSIHVSQ-SGVIYCRD----SDESSSPRQTTSVSQGPAAPLPGLFVQTDAADAIPPSRASGPPSVARVRRARTELGSGSSAGSAAPAATTSRGRRRHCCSSAEAETQT--CYTSVKQVSSAEVRIGPMRLTQDPIQVLLIFAKEDSQSDGFWWACDRAGYRCNIARTPESALECFLDKHHEIIVIDHRQTQNFDAEAVCRSIRATNPSEHTVILAVVSRVSDDHEEASVLPLLHAGFNRRFMENSSIIACYNELIQIEHGEVRSQFKLRACNSVFTALDHCHEAIEIT---SDDHVIQYVNPAFERMMGYHKGELLGKELAD-LPKSDKNRADLLDTINTCIKKGKEWQGVYYARRKSGDSIQQHVKITPVIGQGGKIRHFVSLKKLCCTTDNNKQIHKIHRDSGDNSQTEPHSFRYKNRRKESIDVKSISSRGSDAPSLQNRRYP-SMARIHSMTIEAPITKVINIINAAQENSPVTVAEALDRVLEILRTTELYSPQLGTKDEDP--HTSDLVGGLMTDGL-RRLSGNEYVFTKNVHQSHSHLAMPITINDVPPCISQLLDNEESWDFNIFELEAITHKRPLVYLGLKVFSRFGVCEFLNCSETTLRAWFQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGSLDQLDEVAALIAATVHDVDHPGRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKDTKCNIFKNIDRNHYRTLRQAIIDMVLATEMTKHFEHVNKFVNSINKPMAAEIEGSDC-------ECNPAGKNF--PENQILIKRMMIKCADVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVMPVFDRNTCSIPKSQISFIDYFITDMFDAWDAFAHLPALMQHLADNYKHWKTLDD 873

The following BLAST results are available for this feature:

BLAST of TCONS_00067135-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00067135-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
PDE8B	0.000e+0	43.14	High affinity cAMP-specific and IBMX-insensitive 3...	[more]

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TCONS_00067135-protein (polypeptide) - C. hemisphaerica