TCONS_00063528-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00063528-protein
Unique NameTCONS_00063528-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length435

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00063528-protein ID=TCONS_00063528-protein|Name=TCONS_00063528-protein|organism=Clytia hemisphaerica|type=polypeptide|length=435bp
MRYFIQPSIIFLLLVTRGFSMSTWEHEARLMTHLFGNNTFTSLTRPNPNG
GGALNVTIGLAYVQLMDLDEHRQMLKSNIWIRQYWTNEALAWNPTDYGNI
SVINIDPVHAWLPDIVLYNNARAISAISGGVLYQFKKKLVLHFDGSIQWF
APTIIQTSCHIDPSLYPFDRQNCSVILGSWTHHGFELDVFAQKDSIDTEF
YQESSEFHLVTSQSRKLVQNFSCCAEPYPLLVFDLVFQRHSTYYFINIII
PTALITCLSCLSFVLPSGERVTIGLNVFFTITFINLYNMQKVPQTSTTSL
MNRFLHACTVLTAFCMCSNACVLIMLSLKNVQVPFFIKYLIFEVIAPSVG
LHTNEMFSSTKRREDSSWRIKTDFQVAPKTIYTRIEKELRKDFWRCCAQT
LDRCCFIAFVVLFLSLSLNFVTVDLRDSSRGKLSS
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_039823XLOC_039823Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00063528TCONS_00063528Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR002394Nicotinic_acetylcholine_rcpt
IPR006201Neur_channel
IPR006202Neur_chan_lig-bd
IPR006029Neurotrans-gated_channel_TM
Vocabulary: Molecular Function
TermDefinition
GO:0022848acetylcholine-gated cation-selective channel activity
GO:0005216ion channel activity
GO:0005230extracellular ligand-gated ion channel activity
Vocabulary: Biological Process
TermDefinition
GO:0006811ion transport
Vocabulary: Cellular Component
TermDefinition
GO:0045211postsynaptic membrane
GO:0016021integral component of membrane
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006811 ion transport
cellular_component GO:0016021 integral component of membrane
cellular_component GO:0045211 postsynaptic membrane
molecular_function GO:0022848 acetylcholine-gated cation-selective channel activity
molecular_function GO:0005230 extracellular ligand-gated ion channel activity
molecular_function GO:0005216 ion channel activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR002394Nicotinic acetylcholine receptorPRINTSPR00254NICOTINICRcoord: 63..79
score: 34.9
coord: 97..111
score: 26.52
coord: 115..127
score: 47.01
IPR006201Neurotransmitter-gated ion-channelPRINTSPR00252NRIONCHANNELcoord: 76..92
score: 31.94
coord: 159..173
score: 46.58
coord: 235..247
score: 28.33
coord: 109..120
score: 49.21
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainGENE3D2.70.170.10coord: 18..246
e-value: 3.0E-60
score: 202.9
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainPFAMPF02931Neur_chan_LBDcoord: 28..240
e-value: 9.6E-48
score: 162.4
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainSUPERFAMILY63712Nicotinic receptor ligand binding domain-likecoord: 26..240
NoneNo IPR availableGENE3D1.20.58.390coord: 247..433
e-value: 2.8E-23
score: 81.7
IPR006029Neurotransmitter-gated ion-channel transmembrane domainPFAMPF02932Neur_chan_membcoord: 248..326
e-value: 1.3E-9
score: 38.3
IPR006029Neurotransmitter-gated ion-channel transmembrane domainSUPERFAMILY90112Neurotransmitter-gated ion-channel transmembrane porecoord: 242..419

Blast
[Close]
BLAST of TCONS_00063528-protein vs. Swiss-Prot (Human)
Match: ACH10 (Neuronal acetylcholine receptor subunit alpha-10 OS=Homo sapiens GN=CHRNA10 PE=1 SV=1)

HSP 1 Score: 206.838 bits (525), Expect = 7.253e-62
Identity = 106/306 (34.64%), Postives = 169/306 (55.23%), Query Frame = 0 
Query:   27 EARLMTHLFGN--NTFTSLTRPNPNGGGALNVTIGLAYVQLMDLDEHRQMLKSNIWIRQYWTNEALAWNPTDYGNISVINIDPVHAWLPDIVLYNNARAISAISGGVLYQFKKKLVLHFDGSIQWFAPTIIQTSCHIDPSLYPFDRQNCSVILGSWTHHGFELDVFAQKDSIDTEFYQESSEFHLVTSQSRKLVQNFSCCAEPYPLLVFDLVFQRHSTYYFINIIIPTALITCLSCLSFVLP--SGERVTIGLNVFFTITFINLYNMQKVPQTSTTSLMNRFLHACTVLTAFCMCSNACVLIMLSL 328
            E RL   LF +    +TS  RP  +    LNVT+ +   Q++D+DE  Q+L   +WIRQ WT+  L W+P  YG +  I I     W PDIVLYN A A    S          +VL  DG+++W AP I ++SC +D + +PFD Q+C +  GSWTH G +LDV  +  +     + E+ E+ ++   +R+ V  + CC+EPYP + F L+ +R +  Y  N+++P  LI+ L+ L+F LP  SGE+V++G+ V   +T   L   + +P   +  L+ ++  A   +  F   S A  +++++L
Sbjct:   26 EGRLALKLFRDLFANYTSALRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTLYLWIRQEWTDAYLRWDPNAYGGLDAIRIPSSLVWRPDIVLYNKADAQPPGSA------STNVVLRHDGAVRWDAPAITRSSCRVDVAAFPFDAQHCGLTFGSWTHGGHQLDVRPRGAAASLADFVENVEWRVLGMPARRRVLTYGCCSEPYPDVTFTLLLRRRAAAYVCNLLLPCVLISLLAPLAFHLPADSGEKVSLGVTVLLALTVFQLLLAESMPPAESVPLIGKYYMATMTMVTF---STALTILIMNL 322
The following BLAST results are available for this feature:
BLAST of TCONS_00063528-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
ACH107.253e-6234.64Neuronal acetylcholine receptor subunit alpha-10 O... [more]
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