TCONS_00060554-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00060554-protein
Unique NameTCONS_00060554-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length475

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00060554-protein ID=TCONS_00060554-protein|Name=TCONS_00060554-protein|organism=Clytia hemisphaerica|type=polypeptide|length=475bp
MLRVSQRLMAPVKKFDYLVVGGGSGGIASARRATEFCKSDGSKLKVAVIE
EKRLGGTCVNVGCVPKKVMFNTALHAEMLHDMKDYGFDVTYNGFDWSHVK
TKRDAYVKRLNGMFATNLDKAEVEHIDGHAKFDSDGVCHVGDLQLQGEHT
MIATGGKPLVPNVPGAEYGITSDGFFELEKLPKKTVVVGAGYIAVELAAI
LQTLGSEVHHFIRNDKVLRNFDSLISESITNEHENNVGVKLHKFVDSKSM
KITKCDNTGLLSIETLAGPNKETLQINDAECLLWAVGRVPNTTDLGLEGL
GIKMNEKQEIVVDEFQNTSKPNFYALGDVCGKALLTPVAIAAGRRLSHRL
FNNELDSKLNYDNIPTVVFSHPTIGTIGLTEREAREKYGEENIKIYQSKF
TNMFYTFAENKPQTVLKLVCQLPTEKVVGLHCMGMGCDEMLQGFSVAVKM
GATKKDFDNTVAIHPTSSEEFVTMR
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_038088XLOC_038088Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00060554TCONS_00060554Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR006322Glutathione_Rdtase_euk/bac
IPR023753FAD/NAD-binding_dom
IPR004099Pyr_nucl-diS_OxRdtase_dimer
IPR016156FAD/NAD-linked_Rdtase_dimer
IPR012999Pyr_OxRdtase_I_AS
Vocabulary: Molecular Function
TermDefinition
GO:0050661NADP binding
GO:0004362glutathione-disulfide reductase activity
GO:0050660flavin adenine dinucleotide binding
GO:0016491oxidoreductase activity
GO:0016668oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
Vocabulary: Biological Process
TermDefinition
GO:0055114oxidation-reduction process
GO:0006749glutathione metabolic process
GO:0045454cell redox homeostasis
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0045454 cell redox homeostasis
biological_process GO:0006749 glutathione metabolic process
biological_process GO:0055114 oxidation-reduction process
molecular_function GO:0050660 flavin adenine dinucleotide binding
molecular_function GO:0004362 glutathione-disulfide reductase activity
molecular_function GO:0050661 NADP binding
molecular_function GO:0016491 oxidoreductase activity
molecular_function GO:0016668 oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availablePRINTSPR00368FADPNRcoord: 147..165
score: 28.19
coord: 17..36
score: 35.72
coord: 279..295
score: 38.28
coord: 184..202
score: 40.55
coord: 308..330
score: 36.63
NoneNo IPR availablePRINTSPR00411PNDRDTASEIcoord: 54..69
score: 70.89
coord: 184..209
score: 44.31
coord: 449..469
score: 41.32
coord: 280..294
score: 44.51
coord: 323..330
score: 54.04
coord: 427..442
score: 30.51
coord: 16..38
score: 38.45
coord: 360..381
score: 42.74
coord: 150..159
score: 43.82
NoneNo IPR availableGENE3D1.10.287.990coord: 53..120
e-value: 8.2E-23
score: 80.3
NoneNo IPR availablePIRSFPIRSF000350Hg-II_reductase_MerAcoord: 3..471
e-value: 3.8E-72
score: 241.6
NoneNo IPR availableSFLDSFLDF00172glutathione_reductasecoord: 9..475
e-value: 0.0
score: 606.2
IPR006322Glutathione reductase, eukaryote/bacterialTIGRFAMTIGR01421TIGR01421coord: 13..475
e-value: 1.9E-197
score: 654.9
IPR023753FAD/NAD(P)-binding domainPFAMPF07992Pyr_redox_2coord: 15..343
e-value: 3.2E-55
score: 187.4
IPR023753FAD/NAD(P)-binding domainGENE3D3.50.50.60coord: 130..243
e-value: 9.7E-20
score: 70.3
IPR023753FAD/NAD(P)-binding domainGENE3D3.50.50.60coord: 244..362
e-value: 1.7E-12
score: 47.1
IPR023753FAD/NAD(P)-binding domainSUPERFAMILY51905FAD/NAD(P)-binding domaincoord: 13..389
IPR004099Pyridine nucleotide-disulphide oxidoreductase, dimerisation domainPFAMPF02852Pyr_redox_dimcoord: 364..474
e-value: 4.0E-35
score: 120.3
IPR016156FAD/NAD-linked reductase, dimerisation domainGENE3D3.30.390.30coord: 363..475
e-value: 1.0E-38
score: 131.8
IPR016156FAD/NAD-linked reductase, dimerisation domainSUPERFAMILY55424FAD/NAD-linked reductases, dimerisation (C-terminal) domaincoord: 361..475
IPR012999Pyridine nucleotide-disulphide oxidoreductase, class I, active sitePROSITEPS00076PYRIDINE_REDOX_1coord: 55..65

Blast
[Close]
BLAST of TCONS_00060554-protein vs. Swiss-Prot (Human)
Match: GSHR (Glutathione reductase, mitochondrial OS=Homo sapiens GN=GSR PE=1 SV=2)

HSP 1 Score: 521.546 bits (1342), Expect = 0.000e+0
Identity = 273/471 (57.96%), Postives = 336/471 (71.34%), Query Frame = 0 
Query:   12 VKKFDYLVVGGGSGGIASARRATEFCKSDGSKLKVAVIEEKRLGGTCVNVGCVPKKVMFNTALHAEMLHDMKDYGFDVTYNGFDWSHVKTKRDAYVKRLNGMFATNLDKAEVEHIDGHAKFDSDG--VCHVGDLQLQGEHTMIATGGKPLVPN---VPGAEYGITSDGFFELEKLPKKTVVVGAGYIAVELAAILQTLGSEVHHFIRNDKVLRNFDSLISESITNEHENNVGVKLHKFVDSKSMKITKCDNTGLLSIETLAGPNKETLQ--INDAECLLWAVGRVPNTTDLGLEGLGIKMNEKQEIVVDEFQNTSKPNFYALGDVCGKALLTPVAIAAGRRLSHRLFNNELDSKLNYDNIPTVVFSHPTIGTIGLTEREAREKYGEENIKIYQSKFTNMFYTFAENKPQTVLKLVCQLPTEKVVGLHCMGMGCDEMLQGFSVAVKMGATKKDFDNTVAIHPTSSEEFVTMR 475
            V  +DYLV+GGGSGG+ASARRA E         + AV+E  +LGGTCVNVGCVPKKVM+NTA+H+E +HD  DYGF      F+W  +K KRDAYV RLN ++  NL K+ +E I GHA F SD      V   +    H +IATGG P  P+   +PGA  GITSDGFF+LE+LP ++V+VGAGYIAVE+A IL  LGS+    IR+DKVLR+FDS+IS + T E EN  GV++ KF   K +K T    +GL      A P +  +   I D +CLLWA+GRVPNT DL L  LGI+ ++K  I+VDEFQNT+    YA+GDVCGKALLTPVAIAAGR+L+HRLF  + DSKL+Y+NIPTVVFSHP IGT+GLTE EA  KYG EN+K Y + FT M++   + K + V+K+VC    EKVVG+H  G+GCDEMLQGF+VAVKMGATK DFDNTVAIHPTSSEE VT+R
Sbjct:   62 VASYDYLVIGGGSGGLASARRAAEL------GARAAVVESHKLGGTCVNVGCVPKKVMWNTAVHSEFMHDHADYGFPSCEGKFNWRVIKEKRDAYVSRLNAIYQNNLTKSHIEIIRGHAAFTSDPKPTIEVSGKKYTAPHILIATGGMPSTPHESQIPGASLGITSDGFFQLEELPGRSVIVGAGYIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELEN-AGVEVLKFSQVKEVKKTL---SGLEVSMVTAVPGRLPVMTMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTDDKGHIIVDEFQNTNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFSHPPIGTVGLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKVVGIHMQGLGCDEMLQGFAVAVKMGATKADFDNTVAIHPTSSEELVTLR 522
The following BLAST results are available for this feature:
BLAST of TCONS_00060554-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
GSHR0.000e+057.96Glutathione reductase, mitochondrial OS=Homo sapie... [more]
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