TCONS_00059713-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00059713-protein
Unique NameTCONS_00059713-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length801

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00059713-protein ID=TCONS_00059713-protein|Name=TCONS_00059713-protein|organism=Clytia hemisphaerica|type=polypeptide|length=801bp
MVINSKSKIITKVNIRKAKQQKQAADKMIEKNRPLLIRAYSAESSGGYSY
GKRNNVYGTAHLESSRKEKKVVQFCMRYLSMAIWGIPTMQDTQGLQAIPE
RPESVIEDQNNNILNSDHLQKANKRKLQKSYNPVTNMASQPQDHECTYCL
KIFQSKATLDIHLMTKRHDWQLKKAIENMDSINNEVTTEDDFAKHYLTSG
RNETQQEHSPTLCKEGRYSNGSLVSSEEGYYSTDSDETKHMNTYSTTTAN
GPSCQRRGGVIANGAVDMASYKQRPSVIRLKRMKMEELKEIYKQYAASRG
SGDLYKNLLDTYVDFNFYPDAENRQFSDSEVVNVSAKSNRKYSVSEKEAL
MRRDLVLTEMADTEKNYVDDLAFIINEYFPLMDKDEVSEDLNGDFEKIFG
NIQEIYKFHSRIFSEKIEDCLEDPQLLNETFCQYEDELATLYSQYCKCKP
YADEALHNHQDEIDMLRRKYLPKVKFLLKDYLVTPVQRLMKYQLLLITAK
KYSEKSVAHKIVIKDAIEVMDRVPKLANDAMHVELIKGYEGFLQSEDLLF
QEVIEVDPAPKDNKCKPREMRVFIFDSMVMFCDIVPRKGQLAVYKYVGSG
QTSLMGITETIQNEPYSFAIFFRKFNSTNIYQCKADNKQTKDEWIQVLKD
VIALQMIIMNRASQHTSLDRIDGHKKREGVYRRTSRGKYVNDLVVGETLR
QALQGHPRIGEMSERLKNNIERYILNELIMASEGDPSHFKQRSQSIVPIS
SLVDEWDLKPTCRPRFYSQIDYTRPPYIKDARPKAALVQSITHVSFNQLD
A
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_037561XLOC_037561Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00059713TCONS_00059713Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000219DH-domain
IPR011993PH_dom-like
IPR013087Znf_C2H2_type
Vocabulary: Biological Process
TermDefinition
GO:0035023regulation of Rho protein signal transduction
Vocabulary: Molecular Function
TermDefinition
GO:0005089Rho guanyl-nucleotide exchange factor activity
GO:0003676nucleic acid binding
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0035023 regulation of Rho protein signal transduction
molecular_function GO:0003676 nucleic acid binding
molecular_function GO:0005089 Rho guanyl-nucleotide exchange factor activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000219Dbl homology (DH) domainSMARTSM00325RhoGEF_3coord: 356..529
e-value: 6.7E-24
score: 95.4
IPR000219Dbl homology (DH) domainPFAMPF00621RhoGEFcoord: 356..528
e-value: 2.3E-27
score: 96.3
IPR000219Dbl homology (DH) domainPROSITEPS50010DH_2coord: 352..530
score: 28.289
IPR000219Dbl homology (DH) domainSUPERFAMILY48065DBL homology domain (DH-domain)coord: 352..532
IPR011993PH domain-likeGENE3D2.30.29.30coord: 544..670
e-value: 1.5E-11
score: 43.6
IPR011993PH domain-likeSUPERFAMILY50729PH domain-likecoord: 548..655
NoneNo IPR availableGENE3D1.20.900.10coord: 345..533
e-value: 3.3E-39
score: 134.0
NoneNo IPR availableCDDcd00160RhoGEFcoord: 353..528
e-value: 3.99274E-27
score: 108.539
IPR013087Zinc finger C2H2-typePROSITEPS00028ZINC_FINGER_C2H2_1coord: 146..168

Blast
[Close]
BLAST of TCONS_00059713-protein vs. Swiss-Prot (Human)
Match: ARHGP (Rho guanine nucleotide exchange factor 25 OS=Homo sapiens GN=ARHGEF25 PE=1 SV=2)

HSP 1 Score: 166.392 bits (420), Expect = 1.849e-43
Identity = 113/346 (32.66%), Postives = 177/346 (51.16%), Query Frame = 0 
Query:  346 EKEALMRRDLVLTEMADTEKNYVDDLAFIINEYFPLMDKDEVSEDLNGDFEKIFGNIQEIYKFHSRIFSEKIEDCLEDPQLLNETFCQYEDELATLYSQYCKCKPYADEALHNHQDE-IDMLRRKYLPKVKFLLKDYLVTPVQRLMKYQLLLITAKKYSEKSVAHKIVIKDAIEVMDRVPKLANDAMHVELIKGYEGFLQSED-LLFQEVIEVDPAPKDN--KCKPREMRVFIFDSMVMFCDIVP---RKGQLAVYKYVGSGQTSLMGITETIQNEPYSFAIFFRKF-NSTNIYQCKADNKQTKDEWIQVLKDVIALQMIIMN----------RASQHTSLDRIDG 673
            +K+AL R   VL+E+ +TEK YVDDL  I+  Y   M    V E L G    +FGNIQ+IY++H   F ++++ CL+DP  L + F ++E  L  +Y  YC+ KP ++  +    D   + LR++   +++  L D L+ PVQR+MKYQLLL    KY  ++      ++ A+EVM  VPK  ND M +  ++G+EG L ++  LL Q+   V           + RE RVF+F+ +++F + +    R G    Y Y  S + S +G+   +Q +P  FA+  R        Y  +A +      WI+ +  ++  Q   +N          R SQ  SL R  G
Sbjct:  154 KKKALERSMYVLSELVETEKMYVDDLGQIVEGYMATMAAQGVPESLRGRDRIVFGNIQQIYEWHRDYFLQELQRCLKDPDWLAQLFIKHERRL-HMYVVYCQNKPKSEHVVSEFGDSYFEELRQQLGHRLQ--LNDLLIKPVQRIMKYQLLLKDFLKYYNRAGMDTADLEQAVEVMCFVPKRCNDMMTLGRLRGFEGKLTAQGKLLGQDTFWVTEPEAGGLLSSRGRERRVFLFEQIIIFSEALGGGVRGGTQPGYVYKNSIKVSCLGLEGNLQGDPCRFALTSRGPEGGIQRYVLQAADPAISQAWIKHVAQILESQRDFLNALQSPIEYQRRESQTNSLGRPRG 496
The following BLAST results are available for this feature:
BLAST of TCONS_00059713-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
ARHGP1.849e-4332.66Rho guanine nucleotide exchange factor 25 OS=Homo ... [more]
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