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Sequence
The following sequences are available for this feature:
polypeptide sequence >TCONS_00059541-protein ID=TCONS_00059541-protein|Name=TCONS_00059541-protein|organism=Clytia hemisphaerica|type=polypeptide|length=2326bp
MIFTGCVFSFDLGTSVKYKEKDNLRKQIIENGGTFSYIVTKKTSHLLVNS
IEQAGSSFRCDRSRQYQIPIILTDYVSQCLKEKKLVANDPYLVDKSSSKE
NEELTSGKITAAQPKEDANTKISLHSIRTWSCSDKDTEWDENWNYDVPKC
VFLKAKQKGKTTSFHFLECHASENGKYRVWHQFGSIKTDNKLENKNEDYK
MAVDGSSCEEIFNLWIKSFGSEFSRETLNKKIDIGSRNLYEWPGRASQRI
KPKDLDEVEDLLTVLWKEAHGDLKKFLKNDIKTYTMENISKAEGVLLRLK
DQLKGTKDINEIGTLCNEFYKSIPHKNGEDEKIDSLSKVAGKASLCQLMK
DIVSVSESTNWMTVTNTEAKYNALGCHIRKLSGLELDSQIKEVQNNMNKS
VPRDQLKIKAIYEVNRSSEVKFHGQKTGPFFHSTNPKNFVGILSRGLLLP
KIIVEEFGGQRTDAGMLGSGIYFASDPMTSAKYSKRSSNGYRYRFMLMCK
LALGKTKDFDTYQKDLTEPPYGFDSTHGVPGNDFKDDEYCIYDESRKEIT
HVIEFLEKEDVEQKIFVVDDDEVTVSEDEGIVADLSSDIELTDVENVADP
KDKVVAGLQSNGDQKIPLKAVHVRAKLQDLTSEVIILQQYTNESFEPIEA
KYVFPLDGMAAICGFEAFINGKHIIGKVKEKEEARKEYKEAISKGYGAYL
MEEQEEQPDVFSVSVGNLPPLADVLIKITYVAELPFDGELINFVLPGCVA
PWTKDAAMNTKVQDDLTTVDAGSSNAGDFSLQLSIEMPYEIRQINSPTHS
IKIKKTATNAVVHLEEKSVLGDSFQLHLGLAEIHAPRMIAQQHPTDSNKQ
ACMLTFFPEFESSFENLDVTFFIDASNSMKGELKELKKLVLLAYHLLPEN
VKFNMVAFGEEYYELYDVSHKKTKDVKQRNEVVSFLQPIHTNMGGTHFWK
PLKAIHLLSSSNRPKNIFLFSDGHISDEVSTLATIQKYQQNVRVFTFGLS
STANKHMLRKIANQGCGWYEFFDKAAKSKWQDKVEKQMEKSQQPVLNNIQ
ILWKQHENEAPKPLQAPHQINALFNGSRLVVYGFVPYCTMAYLSSTVNGK
EVNTMVSTTELNTSTGLSFHRLTAKAIINDFENGILHTDRSQHEALKDEM
KKKIISLSIEYSIVTQFTSFVAIEEREENECKDDTAPTMLELVAMETIDI
LPYMGFEGQQKSQDEEKEMDGIDFELDEVETEEEESCERRRSRSRRRSRS
RSRSRSRDRSRAGEKKEKRKASKKKSERISSSSSSASSLSDNEMLSSKRR
SLSSHSSDSGSGDFNELFYQRSPAFTRFSRHRVLKAAAGEPESMGFDDLY
DDVVLCHDEPPRVLKAASGEPEPMDIDDIYDDVDYDLCQEEAEGEYKSMA
ALKNVVELDYTHMCDAIAPPIYEYECAELRSNKMALFDDDDDDDSDDGEY
HSFSLADEEKGPSLRRQEETRSLSSFSSRIDEAKEESIFDNPPIVLDTGM
AEVKAGFAGDDTPKVVIPTLVGRPRHQGVMVGMGQKDAYVGEEAKSKRGI
LTLKSPFERPPKKIPDTMAVAQSAPISKNARTFIKERELAVDSLTYSPTS
RSYSPTSPSYSPTSPVYESAPVRSALPPLTRRSMSMNYCEVACTTTLDEI
AVEMSKMTSYQSLSSARSAVKDNRRVARDVSEKAEALETPSVPPRRPRSA
ARMTANSLDDVEPPQLQQKPKSTFKADSNISLFGVPNSSPAANSLFGSAT
TAASTRFGSIPQDALIDRDQAVFGSRVPAQLQSTGFSGFGSAPPPPPPPA
HARSGDFGSASPPTALRGFGGFGSAPPPPPAPAAFGSAPQSQTMGFGFGS
TSKPLDQPADGFSFGTAPPPPPQSNKPDDLFGGGFGSTPSSATSFGSAPP
PPTLPKSFFGATQPPGDPPGSSLFCESQPPPPPPPPPAEDVQVEKQSFFR
SSRGTAKPRAAFGMKTSIVKKLSEPPPLREEKSRMSLTERLKQRNKEIEA
KESLPEPPKVNSKKKRTKTITFQAMDSQYVVEEAVNDVETLSSRSSLLSS
LKKETVLKKAQQELILHEEEVQRPSKRSAKFKADIFLRKGVLEPPPKAKL
SSCLIDAEPAEKSSTSEVNPYRLKEATKNRKDRKNLREKRRSAGVVIMPS
KPATEPEKENVSEEISNERLVEMGLSLLKEYKDSSLGEELCIWECTDEAK
EKFQLIINEIGIVSFNSRTGMRSIEIFSRLLFTILGVVLIKMKYEISTES
WSSPYHFQTADVSKITDAKDKKSFQDGVKYILKMEKLFPSFHVNYGLGYT
YDEMCVGFVKKLSDGNLVKKSISYLL Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
This polypeptide derives from the following transcript feature(s):
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: Molecular Function
| Term | Definition |
|---|
| GO:0003950 | NAD+ ADP-ribosyltransferase activity |
| GO:0003677 | DNA binding |
Vocabulary: Biological Process
| Term | Definition |
|---|
| GO:0006471 | protein ADP-ribosylation |
| GO:0006366 | transcription from RNA polymerase II promoter |
Vocabulary: Cellular Component
| Term | Definition |
|---|
| GO:0005665 | DNA-directed RNA polymerase II, core complex |
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
| Category |
Term Accession |
Term Name |
| biological_process |
GO:0006471 |
protein ADP-ribosylation |
| biological_process |
GO:0006366 |
transcription from RNA polymerase II promoter |
| cellular_component |
GO:0005665 |
DNA-directed RNA polymerase II, core complex |
| molecular_function |
GO:0003677 |
DNA binding |
| molecular_function |
GO:0003950 |
NAD+ ADP-ribosyltransferase activity |
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
| IPR Term | IPR Description | Source | Source Term | Source Description | Alignment |
|---|
| None | No IPR available | COILS | Coil | Coil | coord: 1466..1486 |
| None | No IPR available | GENE3D | 3.30.420.40 | | coord: 1488..1642
e-value: 9.9E-22
score: 76.7 |
| None | No IPR available | GENE3D | 3.90.228.10 | | coord: 376..578
e-value: 5.1E-25
score: 88.0 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 1224..1314 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 1661..1699 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 1783..2018 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 1437..1482 |
| None | No IPR available | MOBIDB_LITE | mobidb-lite | disorder_prediction | coord: 1595..1619 |
| None | No IPR available | SUPERFAMILY | 53067 | Actin-like ATPase domain | coord: 1490..1559 |
| None | No IPR available | SUPERFAMILY | 56399 | ADP-ribosylation | coord: 389..555 |
| IPR013694 | VIT domain | SMART | SM00609 | vit | coord: 602..732
e-value: 1.2E-32
score: 124.4 |
| IPR013694 | VIT domain | PFAM | PF08487 | VIT | coord: 618..730
e-value: 7.2E-40
score: 135.6 |
| IPR013694 | VIT domain | PROSITE | PS51468 | VIT | coord: 602..732
score: 40.105 |
| IPR002035 | von Willebrand factor, type A | SMART | SM00327 | VWA_4 | coord: 866..1032
e-value: 5.5E-12
score: 55.8 |
| IPR002035 | von Willebrand factor, type A | GENE3D | 3.40.50.410 | | coord: 845..1041
e-value: 1.6E-21
score: 76.2 |
| IPR002035 | von Willebrand factor, type A | PFAM | PF13768 | VWA_3 | coord: 868..1021
e-value: 7.9E-19
score: 68.0 |
| IPR002035 | von Willebrand factor, type A | PROSITE | PS50234 | VWFA | coord: 868..1049
score: 13.687 |
| IPR002035 | von Willebrand factor, type A | SUPERFAMILY | 53300 | vWA-like | coord: 865..1022 |
| IPR001357 | BRCT domain | SMART | SM00292 | BRCT_7 | coord: 2..83
e-value: 8.1E-4
score: 28.7 |
| IPR001357 | BRCT domain | PFAM | PF16589 | BRCT_2 | coord: 2..92
e-value: 3.0E-7
score: 30.7 |
| IPR001357 | BRCT domain | GENE3D | 3.40.50.10190 | | coord: 1..124
e-value: 6.4E-16
score: 58.0 |
| IPR001357 | BRCT domain | PROSITE | PS50172 | BRCT | coord: 1..93
score: 17.568 |
| IPR001357 | BRCT domain | CDD | cd00027 | BRCT | coord: 5..81
e-value: 2.31955E-4
score: 40.7679 |
| IPR001357 | BRCT domain | SUPERFAMILY | 52113 | BRCT domain | coord: 2..95 |
| IPR004000 | Actin family | SMART | SM00268 | actin_3 | coord: 1491..2192
e-value: 3.9E-4
score: -110.5 |
| IPR004000 | Actin family | PFAM | PF00022 | Actin | coord: 1492..1558
e-value: 1.0E-12
score: 47.3 |
| IPR004102 | Poly(ADP-ribose) polymerase, regulatory domain | PFAM | PF02877 | PARP_reg | coord: 285..358
e-value: 1.6E-6
score: 28.2 |
| IPR004102 | Poly(ADP-ribose) polymerase, regulatory domain | GENE3D | 1.20.142.10 | | coord: 260..374
e-value: 8.9E-11
score: 41.4 |
| IPR004102 | Poly(ADP-ribose) polymerase, regulatory domain | PROSITE | PS51060 | PARP_ALPHA_HD | coord: 242..360
score: 9.574 |
| IPR004102 | Poly(ADP-ribose) polymerase, regulatory domain | SUPERFAMILY | 47587 | Domain of poly(ADP-ribose) polymerase | coord: 257..357 |
| IPR012317 | Poly(ADP-ribose) polymerase, catalytic domain | PFAM | PF00644 | PARP | coord: 390..570
e-value: 1.7E-18
score: 66.8 |
| IPR012317 | Poly(ADP-ribose) polymerase, catalytic domain | PROSITE | PS51059 | PARP_CATALYTIC | coord: 365..564
score: 14.663 |
| IPR000684 | RNA polymerase II, heptapeptide repeat, eukaryotic | PROSITE | PS00115 | RNA_POL_II_REPEAT | coord: 1603..1609 |
Blast
BLAST of TCONS_00059541-protein vs. Swiss-Prot (Human)
Match: PARP4 (Poly [ADP-ribose] polymerase 4 OS=Homo sapiens GN=PARP4 PE=1 SV=3) HSP 1 Score: 715.301 bits (1845), Expect = 0.000e+0 Identity = 397/970 (40.93%), Postives = 577/970 (59.48%), Query Frame = 0
Query: 257 EVEDLLTVLWKEAHGDLKKFLKNDIKTYTMENISKAEGVLLRLKDQLKGTKDINEIGTLCNEFYKSIPHKNGEDEKIDSLSKVAGKASLCQLMKDIVSVSESTNWMTVTNTEAKYNALGCHIRKL--SGLELDSQIKEVQNNMNKSVPRDQLKIKAIYEVNRSSEVKFHGQKTGPFFHSTNPKNFVGILSRGLLLPKIIVEEFGGQRTDAGMLGSGIYFASDPMTSAKYSKRS-SNGYRYRFMLMCKLALGKTKDFDTYQKDLTEPPYGFDSTHGVP-----GNDFKDDEYCIYDESRKEITHVIEFLEKEDVEQKIFVVDDDEVTVSEDEGIVADLSSDIELTDVENVADPKDKVVAGLQSNGDQKIPLKAVHVRAKLQDLTSEVIILQQYTNESFEPIEAKYVFPLDGMAAICGFEAFINGKHIIGKVKEKEEARKEYKEAISKGYGAYLMEEQEEQPDVFSVSVGNLPPLADVLIKITYVAELPFDGELINFVLPGCVAPWTKDAAMNTKVQDDLTTV---DAGSSNAGDFSLQLSIEMPYEIRQINSPTHSIKIKKTATNAVVHLEEKSVLGDS-FQLHLGLAEIHAPRMIAQQHPTDSNKQACMLTFFPEFESSFENL----DVTFFIDASNSMKG-ELKELKKLVLLAYHLLPENVKFNMVAFGEEYYELYDVSHKKTKDVKQRNEVVSFLQPIHTNMGGTHFWKPLKAIHLLSSSNRPKNIFLFSDGHISDEVSTLATIQKYQQNVRVFTFGLSSTANKHMLRKIANQGCGWYEFFDKAAKSKWQDKVEKQMEKSQQPVLNNIQILWKQHENEAPKPLQAPHQINALFNGSRLVVYGFVPYCTMAYLSSTVNGKEVNTMVSTTELNTSTGLSFHRLTAKAIINDFENGILHTDRSQHEALKDEMKKKIISLSIEYSIVTQFTSFVAIEEREENECKDDTAPTMLELVAMETIDILPYMGFEGQ 1209
EV DL+ ++W EA G L+ L + ++ ++SKAEG+LL +K LK + ++ + EFY+ IPHK ++++ L +A KA LCQL++D+V+V E+ + AKY AL C I + + E KEV N + P D L+I + VN ++E P H + +N VGIL RGLLLPK+ VE+ G QRTD G LGSGIYF+ TS KYS ++G R +L+C +ALGK D LTE P G+DS HGV DF+DDE+ +Y ++ ++ ++I+F D + D E+ E D +L D + + K AGLQ +PL+ VH++ ++ D ++VI+ Q YTN+S PIEAKY+FPLD AA+CGFEAFINGKHI+G++KEKEEA++EY EA+++G+GAYLM + + PDVF+VSVGNLPP A VLIKITY+ EL G + F +P VAPW +D A+N +QD + + + G+ + FSL +SIEMPY I I S TH +K K+T AV+ E S L S F LH+GL+ + PRM ++HP + +ACML F P+ + +L +V +D S+SM+G + K++ L A L+ E K N++ FG Y EL+ K + F+ MG T FWK L+ + LL + +NI L SDGH+ DE TL +++ + + R+F G+ STAN+H+LR ++ G G +E+F+ +K W+ ++E QM + P +++ + W+Q + P+ LQAP Q+ +LF RL+VYGF+P+CT A L + + KE TMVSTTEL +TG H+L A+A+I D+E+GILH + + HE K +K II LS E S++TQFTSFVA+E+R+ENE P + EL+A E +D LPYM ++G+
Sbjct: 262 EVSDLVEMIWAEALGHLEHMLLKPVNRISLNDVSKAEGILLLVKAALKNGETAEQLQKMMTEFYRLIPHKGTMPKEVN-LGLLAKKADLCQLIRDMVNVCETNLSKPNPPSLAKYRALRCKIEHVEQNTEEFLRVRKEVLQNHHSKSPVDVLQIFRVGRVNETTEFLSKLGNVRPLLHGSPVQNIVGILCRGLLLPKV-VEDRGVQRTDVGNLGSGIYFSDSLSTSIKYSHPGETDGTR--LLLICDVALGKCMDLHEKDFSLTEAPPGYDSVHGVSQTASVTTDFEDDEFVVYKTNQVKMKYIIKFSMPGDQIKDFHPSDHTELEEYRPEFSNFSKVEDYQLPDAKTSSSTK----AGLQDASGNLVPLEDVHIKGRIIDTVAQVIVFQTYTNKSHVPIEAKYIFPLDDKAAVCGFEAFINGKHIVGEIKEKEEAQQEYLEAVTQGHGAYLMSQ--DAPDVFTVSVGNLPPKAKVLIKITYITELSILGTVGVFFMPATVAPWQQDKALNENLQDTVEKICIKEIGTKQS--FSLTMSIEMPYVIEFIFSDTHELKQKRTDCKAVISTMEGSSLDSSGFSLHIGLSAAYLPRMWVEKHP-EKESEACMLVFQPDLDVDLPDLASESEVIICLDCSSSMEGVTFLQAKQIALHALSLVGEKQKVNIIQFGTGYKELFSYP----KHITSNTMAAEFIMSATPTMGNTDFWKTLRYLSLLYPARGSRNILLVSDGHLQDESLTLQLVKRSRPHTRLFACGIGSTANRHVLRILSQCGAGVFEYFNAKSKHSWRKQIEDQMTRLCSPSCHSVSVKWQQLNPDVPEALQAPAQVPSLFLNDRLLVYGFIPHCTQATLCALIQEKEFRTMVSTTELQKTTGTMIHKLAARALIRDYEDGILHENETSHEMKKQTLKSLIIKLSKENSLITQFTSFVAVEKRDENESPFPDIPKVSELIAKEDVDFLPYMSWQGE 1214
The following BLAST results are available for this feature:
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