TCONS_00058142-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00058142-protein
Unique Name	TCONS_00058142-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	1611

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00058142-protein ID=TCONS_00058142-protein|Name=TCONS_00058142-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1611bp
MEDQSRAVASDYQPHEIDNKIEINNNTMTIHAIQEALFEEDETEDGIKKP
PTVQVEPRPKPSKKRANSNVVLRRKHSVPNIVIPSSFGQKINVTFRDDTK
RTSSFKHYSTGYFYNDVQIPQYGANNNHADVINKNGGKKKKKRGLRRTLS
MPSFQKQIVKEEEGRLCEGRKCSELPPQHRHIATKICHHSDCQALNNMNP
LLLCPECDEQNHQEVDFISHLRFDLPSSTTTPINLHRKTSMKSNHSDDSG
TEEDSDASYRFDKKNRSYSSARRFFNISANKNKGRLKKLQSFDQQQESPE
DCFTLQLYDQDENLLAAESVSVKKGRTLKEAIGPLLENYNVNLDTHSIFL
ESSKTPLRLDFITAPLAGNTLHVKATKKMQVDERIVKLMQNVDEQKQPSQ
RQKKTIMSIMSNDDSQAQIKTASLPASNARLTKKGGSSKDLSKSLPDLLQ
QYSMKGFEGSSSINLSDNLDGSEASLVSNDDVEEDLEEKWTDVIDGPEDM
TRSQKNQQEAIWELLSTEYKYVGKIRVILQVFRECLFSLQRDNFLREVDS
ERLFSNIQEIYNTNRIFWSEYLRHVVAETKRTREPIKPSQLLDSFARFED
LFDPYIKYCLEESHCVAYLKQLKETNENFNEYLLWCENQSECHRLKLADL
LVKPMQRVTKYALLLKAVLQRTIDTDEILSLENMISQVDRFVSKINTTLR
LRHEEQKLKTVLNRLENYCPIEATEEVDKVIQDYCNLDLHQKVPGLPEDE
QRCILLDGSMKMIEKQGRLDVQVFLFTDVLLITKAKKNGEKFRIIRPPYR
LNKVVIYPSSQFGSFILIYLNEYGVLVNAFTLQVQNTELTKWMQAIERAK
RRYQAARSGHGSTLDFIDDDLPFSNLSVPSAYTPSMSPLPMRTMNNSISD
ENGLLPPIVVKDEDLPLRSSSSSNFTSSVRGREESSDPTDASVKRSLSDP
KTSVHPRSRDKRMAKTTKARPYSMIQTSERDQVSSWVFNDKRNRSGSIPS
DISDDSRRSSGIGDSFRSINSDTGPQIHRDGKSGNYTEMQSVQKLKKRFE
TGGEYHSDSSSSLASSTQNDPTKPVSRSNSNKRSNPDFTEQQHTIHEEEE
QPNKTRVQLDDSESEAEIDEEEDEEIFRSEEGDTTRTLNGETVLLREIPI
VIESCTQTEPCEKEPYNELYNDTTFSCDKCSSRTTKEQYSSNTDLVSTID
AETSFEMDISDKIEIGVQCGEKKTLTRSVSSQCGDFVQLTGVCEEETDTD
TLRRNNKLFYTADETDGVRSHTPLTPNQTPMMDALTQSLPEYSMNNLKNE
SPRGILKSLSDANIPSLLRDGQAPQGDVRVIHNRSQSDEPRKGQSSGSSP
KHSTVEESPGMRALMVLSENLEELNQQRTSSAGSKPKMSVQQQNSASPSL
RKTAIVNSSPQLKPKTFESVDDEKQVILRSNSSITPSQSWSSSPKQMTKS
LSEQNMYSHKRNTWHESMFQHNKNSSADRTISPVLEEDPKSSMERTFSKS
TEQLNSPRKQKSFKKTLLKKFSDARLIEREQPQQHSSSDDHVTSSVSDTS
MDSKQMKKQMEKEKKEEKKRLKMEKKLEKKEKKYSKRRSGSHTSLTSSIT
SLPTNNVTVQS

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_036640	XLOC_036640	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00058142	TCONS_00058142	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR000219	DH-domain
IPR001849	PH_domain
IPR011993	PH_dom-like
IPR029071	Ubiquitin-rel_dom

Vocabulary: **Biological Process**
Term	Definition
GO:0035023	regulation of Rho protein signal transduction

Vocabulary: **Molecular Function**
Term	Definition
GO:0005089	Rho guanyl-nucleotide exchange factor activity

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0035023	regulation of Rho protein signal transduction
molecular_function	GO:0005089	Rho guanyl-nucleotide exchange factor activity

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
None	No IPR available	COILS	Coil	Coil	coord: 1550..1583
None	No IPR available	COILS	Coil	Coil	coord: 832..852
None	No IPR available	GENE3D	1.20.900.10		coord: 485..717 e-value: 3.7E-48 score: 163.2
None	No IPR available	GENE3D	3.10.20.90		coord: 316..374 e-value: 1.0E-7 score: 31.4
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 916..1037
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 40..68
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 422..443
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1051..1138
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1430..1611
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1333..1359
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1374..1416
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 228..260
None	No IPR available	CDD	cd00160	RhoGEF	coord: 507..696 e-value: 6.79652E-36 score: 135.503
None	No IPR available	CDD	cd13244	PH_PLEKHG5_G6	coord: 752..846 e-value: 1.70428E-28 score: 111.549
IPR000219	Dbl homology (DH) domain	SMART	SM00325	RhoGEF_3	coord: 510..697 e-value: 4.2E-36 score: 135.9
IPR000219	Dbl homology (DH) domain	PFAM	PF00621	RhoGEF	coord: 511..696 e-value: 2.9E-35 score: 122.1
IPR000219	Dbl homology (DH) domain	PROSITE	PS50010	DH_2	coord: 506..698 score: 29.364
IPR000219	Dbl homology (DH) domain	SUPERFAMILY	48065	DBL homology domain (DH-domain)	coord: 496..718
IPR001849	Pleckstrin homology domain	SMART	SM00233	PH_update	coord: 754..853 e-value: 1.1E-5 score: 34.8
IPR011993	PH domain-like	GENE3D	2.30.29.30		coord: 723..856 e-value: 8.5E-14 score: 51.4
IPR011993	PH domain-like	SUPERFAMILY	50729	PH domain-like	coord: 726..851
IPR029071	Ubiquitin-related domain	SUPERFAMILY	54236	Ubiquitin-like	coord: 317..383

Blast

[Close]

BLAST of TCONS_00058142-protein vs. Swiss-Prot (Human)
Match: PKHG5 (Pleckstrin homology domain-containing family G member 5 OS=Homo sapiens GN=PLEKHG5 PE=1 SV=3)

HSP 1 Score: 329.717 bits (844), Expect = 4.185e-94
Identity = 163/376 (43.35%), Postives = 243/376 (64.63%), Query Frame = 0

Query:  486 LEEKWTDVIDGPEDMTRSQKNQQEAIWELLSTEYKYVGKIRVILQVFRECLFSLQRDNFLREVDSERLFSNIQEIYNTNRIFWSEYLRHVVAETKRTREPIKPSQLLDSFARFEDLFDPYIKYCLEESHCVAYLKQLKETNENFNEYLLWCENQSECHRLKLADLLVKPMQRVTKYALLLKAVLQRTIDTDEILSLENMISQVDRFVSKINTTLRLRHEEQKLKTVLNRLENYCPIE-ATEEVDKVIQDYCNLDLHQKVPGLPEDEQRCILLDGSMKMIE-KQGRLDVQVFLFTDVLLITKAKKNGEKFRIIRPPYRLNKVVIYPSSQFGSFILIYLNEYGVLVNAFTLQVQNTELTK-WMQAIERAKRRYQAARS 858
            LE+ W ++IDG E +TR Q +QQEA+WELL TE  Y+ K+RVI+ +F  CL +LQ    L EV++ERLFSNI EI   +R  W+  +  V+ + +RTR  ++P   L  F  F  LF PYI+YC+EE  C+ Y++ L   N+ F  Y+ W E   +C RLKL+D+L KP QR+TKY LLLK+VL++T +     ++  MI  V+RF+  +N  +R R E Q+L  V++R++ Y  +E +++EVDK+++++ +LDL   +PG   +E R +LL+GS++M E K  ++DV  FLFTD+LL+TKA K  E+ R+IRPP  ++K+V       GSF+LIYLNE+   V A+T Q     L + W+  I  A+ + Q  R+
Sbjct:  372 LEDSWRELIDGHEKLTRRQCHQQEAVWELLHTEASYIRKLRVIINLFLCCLLNLQESGLLCEVEAERLFSNIPEIAQLHRRLWASVMAPVLEKARRTRALLQPGDFLKGFKMFGSLFKPYIRYCMEEEGCMEYMRGLLRDNDLFRAYITWAEKHPQCQRLKLSDMLAKPHQRLTKYPLLLKSVLRKTEEPRAKEAVVAMIGSVERFIHHVNACMRQRQERQRLAAVVSRIDAYEVVESSSDEVDKLLKEFLHLDLTAPIPGASPEETRQLLLEGSLRMKEGKDSKMDVYCFLFTDLLLVTKAVKKAERTRVIRPPLLVDKIVCRELRDPGSFLLIYLNEFHSAVGAYTFQASGQALCRGWVDTIYNAQNQLQQLRA 747

HSP 2 Score: 90.8929 bits (224), Expect = 3.902e-18
Identity = 72/271 (26.57%), Postives = 120/271 (44.28%), Query Frame = 0

Query:  161 EEEGRLCEGRKCSELPPQHRHIATKICHHSDCQALNNMNPLLLCPECDEQNHQEVDFISHLRFDLPSSTTTPINLHRKTSMKSNHSDDSGTEEDSDASYRFDKKNRSYSSARRFFNISANKNKGRLKKLQSFDQQQESPEDCFTLQLYDQDENL-LAAESVSVKKGRTLKEAIGPLLENYNVNLDTHSIFLESSKTPLRLDFITAPLAGNTLHVKATKKMQVDERIVKLMQNVDEQKQPSQRQKKTIMSIMSNDDSQAQIKTASLPASNAR 430
            E++G  C+   C +     +  A K+CHH+DCQ L+   PL LC  CD + H  + +  H+RFDLP   +    L R  S +S       T    D     ++ +      R+   +  +K K R +         +  ++CFTL+    D N+ +  E V   K ++L E + P+ E   + L    I+L+ S TPL L F      G+ L VKA  K   + ++ + M++      P  R   T    +   D+Q++ ++  + A   R
Sbjct:    8 EKKGLRCQNPACMD-----KGRAAKVCHHADCQQLHRRGPLNLCEACDSKFHSTMHYDGHVRFDLPPQGSV---LARNVSTRSCPPR---TSPAVDLEEEEEESSVDGKGDRKSTGLKLSKKKARRR------HTDDPSKECFTLKF---DLNVDIETEIVPAMKKKSLGEVLLPVFERKGIALGKVDIYLDQSNTPLSLTFEAYRFGGHYLRVKAPAKPGDEGKVEQGMKDSKSLSLPILRPAGTGPPALERVDAQSRRESLDILAPGRR 258

The following BLAST results are available for this feature:

BLAST of TCONS_00058142-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00058142-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
PKHG5	4.185e-94	43.35	Pleckstrin homology domain-containing family G mem...	[more]

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TCONS_00058142-protein (polypeptide) - C. hemisphaerica