TCONS_00055972-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00055972-protein
Unique Name	TCONS_00055972-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	927

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00055972-protein ID=TCONS_00055972-protein|Name=TCONS_00055972-protein|organism=Clytia hemisphaerica|type=polypeptide|length=927bp
MKAHQTRCITWCLAFVLIAQVSAQSAAWDKWGVWSNCTRPCGGGVTQRSR
QCIGESDGLSCEGKSVEYSMCNIQDCPDGTPNFRMKQCSAYDNKPFKGKI
FRWASFTHGAGECELKCMPKKHFFYVTFKDKVIDGTRCNPYTLDVCINGT
CQPVGCDNQLFSDAKFDECGVCRGDGSTCVQLKDTYKPIEGAYGYVKVTK
IAEGATSVYIKENGDPDMYLALTTSSGKNVLNGDYIFTSPRKMKLHGNIM
HYERNAQVNQITIDGPTEVPLQLKVFVMEGSEQQNNISFQYMLPKADAPI
EQPKRAEYVYVENEWTECTKSCATGFRSRSYFCANRVTKEKVEAFYCNNL
QRPVTRERCNTQSCPARWYISQWAACSTTCGRGLRARRVHCVRTQPDGNI
EMLSLEKCPGETPRRVEVCVDQGSCPKWFANEWSQCSQSCGNGVQTRQVE
CMSMEDNSVEATKCSEAEKPIIQQPCHNAPCGSLWKTGPWRECSAECGRG
MRMRQVTCENSEGFEVPASFCDKENEPKHYEECTAEEGECKPRWQTTMWS
KCSSKCGRGMQYRSSYCTLLNPELNRMSVLKNTECPSDEQPIVVRRCKNE
KPCRVRYFVSRWSKCSVSCGTGIAKRTIQCYADRNIDYSKHACAKLQEPI
SFKLCDMPKCDGSDEITTPLSQTTTPVPSTTKTVSLKGPVILHKGDNADY
TCTVTGLRNPKITWYSDDKPLMSNSRLRPVDARFGSKLIVLSASEEDGGR
LKCYAEDGNQKGEDSLDVLVYVKPTTKLSQTSTNVKAGQSLTITCQVEGF
PKPRVQWQKNDDVFRVDGLRITRTDSAITFKRLVTSDSGKYDCIAFNAAG
SSTSTANLKVAADENANESISTGEESSTSTDDNNCQDQQNTCNLAKQMKL
CEFPHYEKRVCCKTCRKLANEVIKKSR

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_035233	XLOC_035233	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00055972	TCONS_00055972	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR013273	Peptidase_M12B_ADAM-TS
IPR000884	TSP1_rpt
IPR003599	Ig_sub
IPR003598	Ig_sub2
IPR013783	Ig-like_fold
IPR013098	Ig_I-set
IPR010294	ADAM_spacer1
IPR007110	Ig-like_dom

Vocabulary: **Molecular Function**
Term	Definition
GO:0008270	zinc ion binding
GO:0004222	metalloendopeptidase activity

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
molecular_function	GO:0004222	metalloendopeptidase activity
molecular_function	GO:0008270	zinc ion binding

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR013273	Peptidase M12B, ADAM-TS	PRINTS	PR01857	ADAMTSFAMILY	coord: 160..179 score: 57.76 coord: 140..159 score: 47.04 coord: 34..52 score: 54.03
IPR000884	Thrombospondin type-1 (TSP1) repeat	SMART	SM00209	TSP1_2	coord: 309..365 e-value: 0.024 score: 23.6 coord: 484..541 e-value: 0.0024 score: 27.1 coord: 427..482 e-value: 0.0029 score: 26.8 coord: 368..426 e-value: 0.0049 score: 26.1 coord: 543..604 e-value: 0.24 score: 14.8 coord: 606..661 e-value: 2.4E-4 score: 30.5 coord: 28..77 e-value: 3.6E-9 score: 46.5
IPR000884	Thrombospondin type-1 (TSP1) repeat	PFAM	PF00090	TSP_1	coord: 371..421 e-value: 9.4E-5 score: 22.5 coord: 432..481 e-value: 5.5E-6 score: 26.4 coord: 30..76 e-value: 6.6E-8 score: 32.6 coord: 487..527 e-value: 8.6E-6 score: 25.8 coord: 546..603 e-value: 0.064 score: 13.4 coord: 610..660 e-value: 6.5E-6 score: 26.2
IPR000884	Thrombospondin type-1 (TSP1) repeat	GENE3D	2.20.100.10		coord: 307..365 e-value: 8.4E-11 score: 41.6 coord: 604..660 e-value: 9.1E-10 score: 38.3 coord: 482..539 e-value: 6.8E-12 score: 45.1 coord: 540..603 e-value: 7.0E-8 score: 32.3 coord: 427..481 e-value: 3.6E-13 score: 49.2
IPR000884	Thrombospondin type-1 (TSP1) repeat	GENE3D	2.20.100.10		coord: 22..77 e-value: 2.2E-12 score: 46.7 coord: 366..426 e-value: 9.1E-10 score: 38.3
IPR000884	Thrombospondin type-1 (TSP1) repeat	PROSITE	PS50092	TSP1	coord: 424..482 score: 11.425
IPR000884	Thrombospondin type-1 (TSP1) repeat	PROSITE	PS50092	TSP1	coord: 484..537 score: 9.06
IPR000884	Thrombospondin type-1 (TSP1) repeat	PROSITE	PS50092	TSP1	coord: 606..661 score: 8.445
IPR000884	Thrombospondin type-1 (TSP1) repeat	PROSITE	PS50092	TSP1	coord: 25..77 score: 11.934
IPR000884	Thrombospondin type-1 (TSP1) repeat	PROSITE	PS50092	TSP1	coord: 364..423 score: 10.182
IPR000884	Thrombospondin type-1 (TSP1) repeat	PROSITE	PS50092	TSP1	coord: 540..604 score: 9.442
IPR000884	Thrombospondin type-1 (TSP1) repeat	SUPERFAMILY	82895	TSP-1 type 1 repeat	coord: 543..603
IPR000884	Thrombospondin type-1 (TSP1) repeat	SUPERFAMILY	82895	TSP-1 type 1 repeat	coord: 368..422
IPR000884	Thrombospondin type-1 (TSP1) repeat	SUPERFAMILY	82895	TSP-1 type 1 repeat	coord: 310..364
IPR000884	Thrombospondin type-1 (TSP1) repeat	SUPERFAMILY	82895	TSP-1 type 1 repeat	coord: 606..660
IPR000884	Thrombospondin type-1 (TSP1) repeat	SUPERFAMILY	82895	TSP-1 type 1 repeat	coord: 25..76
IPR000884	Thrombospondin type-1 (TSP1) repeat	SUPERFAMILY	82895	TSP-1 type 1 repeat	coord: 424..481
IPR000884	Thrombospondin type-1 (TSP1) repeat	SUPERFAMILY	82895	TSP-1 type 1 repeat	coord: 484..535
IPR003599	Immunoglobulin subtype	SMART	SM00409	IG_3c	coord: 780..861 e-value: 2.1E-9 score: 47.3 coord: 687..773 e-value: 9.5E-4 score: 28.5
IPR003598	Immunoglobulin subtype 2	SMART	SM00408	igc2_5	coord: 786..850 e-value: 2.4E-12 score: 57.0 coord: 693..760 e-value: 7.3E-4 score: 28.8
IPR013783	Immunoglobulin-like fold	GENE3D	2.60.40.10		coord: 676..776 e-value: 4.2E-14 score: 52.0
IPR013783	Immunoglobulin-like fold	GENE3D	2.60.40.10		coord: 777..877 e-value: 1.2E-21 score: 76.3
IPR013098	Immunoglobulin I-set	PFAM	PF07679	I-set	coord: 689..768 e-value: 1.3E-9 score: 37.9 coord: 781..860 e-value: 2.5E-16 score: 59.4
IPR010294	ADAM-TS Spacer 1	PFAM	PF05986	ADAM_spacer1	coord: 183..294 e-value: 7.0E-21 score: 74.3
IPR007110	Immunoglobulin-like domain	PROSITE	PS50835	IG_LIKE	coord: 774..859 score: 13.856
IPR007110	Immunoglobulin-like domain	PROSITE	PS50835	IG_LIKE	coord: 678..769 score: 10.771
IPR007110	Immunoglobulin-like domain	SUPERFAMILY	48726	Immunoglobulin	coord: 768..860
IPR007110	Immunoglobulin-like domain	SUPERFAMILY	48726	Immunoglobulin	coord: 689..774
None	No IPR available	CDD	cd00096	Ig	coord: 701..765 e-value: 3.7885E-6 score: 44.7875

Blast

[Close]

BLAST of TCONS_00055972-protein vs. Swiss-Prot (Human)
Match: ATS6 (A disintegrin and metalloproteinase with thrombospondin motifs 6 OS=Homo sapiens GN=ADAMTS6 PE=2 SV=2)

HSP 1 Score: 309.686 bits (792), Expect = 6.468e-90
Identity = 178/523 (34.03%), Postives = 261/523 (49.90%), Query Frame = 0

Query:   26 AAWDKWGVWSNCTRPCGGGVTQRSRQCIGES---DGLSCEGKSVEYSMCNIQDCPDGTPNFRMKQCSAYDNKPFKGKIFRWASFTHGAGE-CELKCMPKKHFFYVTFKDKVIDGTRCNPYTLDVCINGTCQPVGCDNQLFSDAKFDECGVCRGDGSTCVQLKDTYKPIEGAYGYVKVTKIAEGATSVYIKENGDPDMYLALTTSSGKNVLNGDYIFTSPRKMKLHGNIMHYER-NAQVNQITIDGPTEVPLQLKVFVMEGSEQQNNISFQYMLPKADAPIEQPKRAE----YVYVENEWTECTKSCATGFRSRSYFCANRVTKEKVEAFYCNNLQRPVTRER-CNTQSCPARWYISQWAACSTTCGRGLRARRVHCVRTQPDGNIEMLSLEKCPGETPRRVEVCVDQGSCPKWFANEWSQCSQSCGNGVQTRQVECMSME-DNSVEATKCSEAEKPIIQQPCHNAPC-GSLWKTGPWRECSAECGRGMRMRQVTCENSEGFEVPASFCDKENEPKHYEECTAE 536
              W  W +W  C+R CGGGV+   R C   +    G  C G+   Y  CN   CP G+ +FR KQC+ +DN PF+GK + W  +T G  + C L C+ + + FY      VIDGT+CN  +LD+CING C+ VGCDN L SDA+ D C VC GDGSTC  ++  +       GY++V +I  G+  + ++E      Y+AL +      +NG +    PRK  + G   HY+R   +   +   GPT   L + V +     Q+ N+  +Y   K + PI +    +    + +    W+EC+ +CA G + +   C        V+  YC+   +P   +R CNT+ CP  W+I  W  CS TC  G+R R V C+R       E L    C    P   E C +Q   P+W A +WS+C+  CG G + R V C S +   +  A +C E  KP ++  C    C    W TG W +CSA+CG G +MR V C +  G    +S C +   P   ++C ++
Sbjct:  559 GGWGPWSLWGECSRTCGGGVSSSLRHCDSPAPSGGGKYCLGERKRYRSCNTDPCPLGSRDFREKQCADFDNMPFRGKYYNWKPYTGGGVKPCALNCLAEGYNFYTERAPAVIDGTQCNADSLDICINGECKHVGCDNILGSDAREDRCRVCGGDGSTCDAIEGFFNDSLPRGGYMEVVQIPRGSVHIEVREVAMSKNYIALKSEGDDYYINGAWTIDWPRKFDVAGTAFHYKRPTDEPESLEALGPTSENLIVMVLL-----QEQNLGIRY---KFNVPITRTGSGDNEVGFTWNHQPWSECSATCAGGVQRQEVVCKRLDDNSIVQNNYCDPDSKPPENQRACNTEPCPPEWFIGDWLECSKTCDGGMRTRAVLCIRKIGPSEEETLDYSGCLTHRPVEKEPCNNQSCPPQWVALDWSECTPKCGPGFKHRIVLCKSSDLSKTFPAAQCPEESKPPVRIRCSLGRCPPPRWVTGDWGQCSAQCGLGQQMRTVQCLSYTG--QASSDCLETVRPPSMQQCESK 1071

HSP 2 Score: 115.546 bits (288), Expect = 4.004e-26
Identity = 84/255 (32.94%), Postives = 122/255 (47.84%), Query Frame = 0

Query:  428 WFANEWSQCSQSCGNGVQTRQVECMSMEDNS-VEATKCS-EAEKPIIQQPCHNAPCGSLWKTGPWRECSAECGRGMRMRQVTCEN----SEGFEVPASFCDKENEPKHYEECTAEEGECKPRWQTTMWSKCSSKCGRGMQYRSSYCTLLNPELNRMSVLKNTECPSDEQPIVVRRCKNEKPCRVRYFVSRWSKCSVSCGTGIAKRTIQCYADRNIDYSKHA---CAKLQEPISFKLCDMPKCDGSDEITTPLSQT 673
            W    WS+CS +C  GVQ ++V C  ++DNS V+   C  +++ P  Q+ C+  PC   W  G W ECS  C  GMR R V C      SE   +  S C   + P   E C  +   C P+W    WS+C+ KCG G ++R   C   + +L++       +CP + +P V  RC   +    R+    W +CS  CG G   RT+QC     + Y+  A   C +   P S + C+  KCD     +TP+S T
Sbjct:  844 WNHQPWSECSATCAGGVQRQEVVCKRLDDNSIVQNNYCDPDSKPPENQRACNTEPCPPEWFIGDWLECSKTCDGGMRTRAVLCIRKIGPSEEETLDYSGC-LTHRPVEKEPCNNQS--CPPQWVALDWSECTPKCGPGFKHRIVLCK--SSDLSK--TFPAAQCPEESKPPVRIRCSLGRCPPPRWVTGDWGQCSAQCGLGQQMRTVQC-----LSYTGQASSDCLETVRPPSMQQCE-SKCD-----STPISNT 1080

The following BLAST results are available for this feature:

BLAST of TCONS_00055972-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00055972-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
ATS6	6.468e-90	34.03	A disintegrin and metalloproteinase with thrombosp...	[more]

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TCONS_00055972-protein (polypeptide) - C. hemisphaerica