TCONS_00053790-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00053790-protein
Unique NameTCONS_00053790-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length604

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00053790-protein ID=TCONS_00053790-protein|Name=TCONS_00053790-protein|organism=Clytia hemisphaerica|type=polypeptide|length=604bp
MKLILLVFGLIQAHASVLDVFAFTNGHEPRVAMNCDHVPFYIDLKTGSWV
EDSEGLEICDHNKEVVKKYCQKMYPKLNITNIVEANTPQTFNNWCRSGQS
QCTEAKEVVPYRCLVNEYEADALMVPDGCKFDHIHDPNQCLSHDQWKEKA
SKKCDSQYKMKLKDYGILLSCGTDVFTGVEFVCCPEKMPETKPAPSAATP
KITKDVFQAAVAKFLQYLPSVTKGCDRSTYLTKQASMGEHHQSQIAAVVD
EWDNAEKRYNDLKKKDPVVAEEKMKRTLEVFRQTLAALEQESKDEKERLR
VEHADCINTQISKDKRDAMINYLASIQKEPANADEILGAVRKFIQVCEHD
RVHSLRHFEHVRRRNASEADSIRSELLQHLKGLNKVVNESMALLNYLPTI
AKKFGLTGNTAVLKPKTELPEIKHEDHVHERVKEILENNKHLEEDDDEDD
DDDDEESIFVTSKPVPLKKLLAAAKIKNTVEKTPTIKSLGKMAAKIKNEY
DDSDDEDDDNDIIADAFPVPQKDAPTHHKGKKEHHRSPMVINIILGLCCG
ILVVMLIVVIVMVVQRRRVAHTRVVIAENNDDREHLIQMQKSGFENPTYK
FFYY
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_033950XLOC_033950Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00053790TCONS_00053790Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR008155Amyloid_glyco
IPR008154Amyloid_glyco_extra
IPR015849Amyloid_glyco_heparin-bd
IPR019543APP_amyloid_C
IPR024329Amyloid_glyco_E2_domain
IPR011178Amyloid_glyco_Cu-bd
IPR019744Amyloid_glyco_extracell_CS
Vocabulary: Cellular Component
TermDefinition
GO:0016021integral component of membrane
Vocabulary: Molecular Function
TermDefinition
GO:0008201heparin binding
GO:0046914transition metal ion binding
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
cellular_component GO:0016021 integral component of membrane
molecular_function GO:0008201 heparin binding
molecular_function GO:0046914 transition metal ion binding
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 245..265
NoneNo IPR availableCOILSCoilCoilcoord: 271..305
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 436..458
IPR008155Amyloidogenic glycoproteinPRINTSPR00203AMYLOIDA4coord: 536..561
score: 11.97
coord: 174..192
score: 48.54
coord: 582..604
score: 51.69
IPR008154Amyloidogenic glycoprotein, extracellularSMARTSM00006A4_EXTRA_3coord: 22..185
e-value: 4.6E-64
score: 228.8
IPR015849Amyloidogenic glycoprotein, heparin-bindingGENE3D3.90.570.10coord: 28..118
e-value: 1.9E-29
score: 101.3
IPR015849Amyloidogenic glycoprotein, heparin-bindingPFAMPF02177APP_Ncoord: 28..127
e-value: 1.0E-33
score: 115.6
IPR015849Amyloidogenic glycoprotein, heparin-bindingSUPERFAMILY56491A heparin-binding domaincoord: 27..118
IPR019543Beta-amyloid precursor protein C-terminalPFAMPF10515APP_amyloidcoord: 557..602
e-value: 2.4E-10
score: 40.7
IPR024329Amyloidogenic glycoprotein, E2 domainPFAMPF12925APP_E2coord: 216..394
e-value: 4.5E-45
score: 153.6
IPR024329Amyloidogenic glycoprotein, E2 domainSUPERFAMILY109843CAPPD, an extracellular domain of amyloid beta A4 proteincoord: 217..404
IPR011178Amyloidogenic glycoprotein, copper-bindingGENE3D3.30.1490.140coord: 128..185
e-value: 2.2E-22
score: 79.1
IPR011178Amyloidogenic glycoprotein, copper-bindingPFAMPF12924APP_Cu_bdcoord: 128..185
e-value: 3.0E-21
score: 75.8
IPR011178Amyloidogenic glycoprotein, copper-bindingSUPERFAMILY89811Amyloid beta a4 protein copper binding domain (domain 2)coord: 121..185
IPR019744Amyloidogenic glycoprotein, extracellular domain conserved sitePROSITEPS00319A4_EXTRAcoord: 178..185

Blast
[Close]
BLAST of TCONS_00053790-protein vs. Swiss-Prot (Human)
Match: APLP1 (Amyloid-like protein 1 OS=Homo sapiens GN=APLP1 PE=1 SV=3)

HSP 1 Score: 200.29 bits (508), Expect = 4.266e-56
Identity = 161/640 (25.16%), Postives = 280/640 (43.75%), Query Frame = 0 
Query:   30 RVAMNCDHVPFYIDLKTGSWVEDSEGLEICDHNKEVVKKYCQKMYPKLNITNIVEANTPQTFNNWCRSGQS-QCTEAK-EVVPYRCLVNEYEADALMVPDGCKFDHIHDPNQCLSHDQWKEKASKKCDSQYKMKLKDYGILLSCGTDVFTGVEFVCCPEKMPETKPAPSAAT---------------------------PKITKDVF----QA---------------AVAKFLQYLPSVTKGCD-----------RSTYLTKQASMGEHHQSQIAAVVDEWDNAEKRYNDLKKKDPVVAEEKMKRTL-EVFRQTLAALEQESKDEKERLRVEHADCINTQISKDKRDAMINYLASIQKEPANADEILGAVRKFIQVCEHDRVHSLRHFEHVRRRNASEADSIRSELLQHLKGLNKVVNESMALLNYLPTIAKKFGLTGNTAVLKPKTELPEIKHEDHVHERVKEIL------ENNKHLEEDDDEDDDDDDEESIFVTSKPVPLKKLLAAAKIKNTVEKTPTIKSLGKMAAKIKNEYDDSDDEDDDNDIIADAFPVPQKDAPTHHKGKKEHHRSPMVINIILGLCCGILVVMLIVVIVMVVQRRRVAHTRVVIAEN-NDDREHLIQMQKSGFENPTYKFF 602
            +VA  C  +  + DL+TG W  D +    C  + + V +YC++MYP+L I  + +A        WC   +S  C     +VVP+RCL  E+ ++AL+VP+GC+F H    +QC S  +  ++A + C SQ  + L   G+LL CG+D F GVE+VCCP   P   P PS                              P+   D F    QA               AV   +   P  T G D              +L  +  + E    QI  V+ EW  A+ +  +L K D        ++ L E F+  L  LE++   E++RL   HA  +   I+  +R A+  +LA++Q +P  A+ +L A+R++++  + ++ H+LRH++HV   +  +A  +R ++  HL+ + + VN+S+ LL+  P +A++         L+P+ +  E+ H +H+     E        E+   L+  D +DD          T   +P       A      +  P  +   K+ A +   +     E   +++      V                R  +   +I+G   G L+V+ ++++        ++H  V +      + + L ++Q+ G+ENPTY+F 
Sbjct:   55 QVAGLCGRLTLHRDLRTGRWEPDPQRSRRCLRDPQRVLEYCRQMYPELQIARVEQATQAIPMERWCGGSRSGSCAHPHHQVVPFRCLPGEFVSEALLVPEGCRFLHQERMDQCESSTRRHQEAQEACSSQ-GLILHGSGMLLPCGSDRFRGVEYVCCP---PPGTPDPSGTAVGDPSTRSWPPGSRVEGAEDEEEEESFPQPVDDYFVEPPQAEEEEETVPPPSSHTLAVVGKVTPTPRPTDGVDIYFGMPGEISEHEGFLRAKMDLEERRMRQINEVMREWAMADNQSKNLPKAD--------RQALNEHFQSILQTLEEQVSGERQRLVETHATRVIALINDQRRAALEGFLAALQADPPQAERVLLALRRYLRAEQKEQRHTLRHYQHVAAVDPEKAQQMRFQVHTHLQVIEERVNQSLGLLDQNPHLAQE---------LRPQIQ--ELLHSEHLGPSELEAPAPGGSSEDKGGLQPPDSKDD----------TPMTLPKGSTEQDAASPEKEKMNPLEQYERKVNASVPRGFPFHSSEIQRDELAPAGTGV---------------SREAVSGLLIMGAGGGSLIVLSMLLLRRKKPYGAISHGVVEVDPMLTLEEQQLRELQRHGYENPTYRFL 646
The following BLAST results are available for this feature:
BLAST of TCONS_00053790-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
APLP14.266e-5625.16Amyloid-like protein 1 OS=Homo sapiens GN=APLP1 PE... [more]
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