TCONS_00050449-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00050449-protein
Unique NameTCONS_00050449-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length521

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00050449-protein ID=TCONS_00050449-protein|Name=TCONS_00050449-protein|organism=Clytia hemisphaerica|type=polypeptide|length=521bp
MSQCLSLNEKKSQKCFEDLNCFETCGKNQVCTIFYRNMTGELQPGFAGCW
EKEGKGFCNPDHLTHIDCHLRHKGKHNGIDSFMCCCTGNRCNKNLIQNAT
LMTPTPSTSTETTLMTELPKHPESKTLQYSIPPVICSIFVVIALLYFWKR
HKQRIPSGHPLILYQPPTPIITKPVQWDRVVNVGQFGCVWKATYNNNEVA
VKIIQAHEKSYWITEKTMYQYNLVHDNILKFYSAEKRLSDSNMIQYWIVT
QYHANGSLADYLSSNTLDWTLMLQLAISMTQGIAYLHEEIMTETIRKPII
AHRDIKSRNVLVRDNLTCCISDFGSACQFSENTDKEEIKGQVGTKRYMAP
EVLEGAVAFQTESYKSIDCYSLSLILWELLSRCDTGQVPAEPVYQLPFEA
EVGTNPTLEELRACVSEQGMRPKLKAGWTRDPKVTELCNTIEEGWDKEGD
ARLSAPGVLQRLKELQLAAEGGEVNPTQATRINIPPYGDGDSTLGGNSTG
VSFLSGSTSSCGKEPLIVDLS
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_031950XLOC_031950Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00050449TCONS_00050449Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR000333TGFB_receptor
IPR000719Prot_kinase_dom
IPR008271Ser/Thr_kinase_AS
IPR011009Kinase-like_dom
Vocabulary: Molecular Function
TermDefinition
GO:0004702signal transducer, downstream of receptor, with serine/threonine kinase activity
GO:0005524ATP binding
GO:0004672protein kinase activity
Vocabulary: Biological Process
TermDefinition
GO:0007178transmembrane receptor protein serine/threonine kinase signaling pathway
GO:0006468protein phosphorylation
Vocabulary: Cellular Component
TermDefinition
GO:0016020membrane
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006468 protein phosphorylation
biological_process GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway
cellular_component GO:0016020 membrane
molecular_function GO:0005524 ATP binding
molecular_function GO:0004672 protein kinase activity
molecular_function GO:0004702 signal transducer, downstream of receptor, with serine/threonine kinase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR000333Ser/Thr protein kinase, TGFB receptorPRINTSPR00653ACTIVIN2Rcoord: 433..452
score: 49.67
coord: 6..24
score: 24.56
coord: 313..334
score: 39.39
IPR000719Protein kinase domainSMARTSM00220serkin_6coord: 175..468
e-value: 1.8E-16
score: 70.8
IPR000719Protein kinase domainPFAMPF00069Pkinasecoord: 183..383
e-value: 9.3E-31
score: 107.0
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 175..465
score: 33.828
NoneNo IPR availableGENE3D1.10.510.10coord: 270..471
e-value: 5.1E-36
score: 123.3
NoneNo IPR availableGENE3D3.30.200.20coord: 108..269
e-value: 3.8E-14
score: 52.1
NoneNo IPR availableGENE3D2.10.60.10coord: 2..101
e-value: 1.0E-6
score: 28.6
IPR008271Serine/threonine-protein kinase, active sitePROSITEPS00108PROTEIN_KINASE_STcoord: 300..312
IPR011009Protein kinase-like domainSUPERFAMILY56112Protein kinase-like (PK-like)coord: 155..462

Blast
[Close]
BLAST of TCONS_00050449-protein vs. Swiss-Prot (Human)
Match: AVR2A (Activin receptor type-2A OS=Homo sapiens GN=ACVR2A PE=1 SV=1)

HSP 1 Score: 298.13 bits (762), Expect = 4.391e-95
Identity = 170/460 (36.96%), Postives = 256/460 (55.65%), Query Frame = 0 
Query:   21 CFETCGKNQVCTIFYRNMTGELQPGFAGCWEKEGKGFCNPDHLTHIDCHLRHK--GKHNGIDSFMCCCTGNRCNKNLIQNATLMTPTPSTSTETTLMTELPKHPESKTLQYSIPPVICSIFVVIALLYFWKRHKQRIPSGHPLILYQPPT----------PIITKPVQWDRVVNVGQFGCVWKATYNNNEVAVKIIQAHEKSYWITEKTMYQY-NLVHDNILKFYSAEKRLSDSNMIQYWIVTQYHANGSLADYLSSNTLDWTLMLQLAISMTQGIAYLHEEI-MTETIRKPIIAHRDIKSRNVLVRDNLTCCISDFGSACQFSENTDKEEIKGQVGTKRYMAPEVLEGAVAFQTESYKSIDCYSLSLILWELLSRCDTGQVPAEPVYQLPFEAEVGTNPTLEELRACVSEQGMRPKLKAGWTRDPKVTELCNTIEEGWDKEGDARLSAPGVLQRLKELQ 466
            C+    K + C   ++N++G ++    GCW            L  I+C+ R     K +  + + CCC GN CN+       +    P+++  T      PK P    L YS+ P++    +VI   + ++ HK   P   P+++   PT           +  KP+Q   V   G+FGCVWKA   N  VAVKI    +K  W  E  +Y    + H+NIL+F  AEKR +  + +  W++T +H  GSL+D+L +N + W  +  +A +M +G+AYLHE+I   +   KP I+HRDIKS+NVL+++NLT CI+DFG A +F       +  GQVGT+RYMAPEVLEGA+ FQ +++  ID Y++ L+LWEL SRC     P +  Y LPFE E+G +P+LE+++  V  +  RP L+  W +   +  LC TIEE WD + +ARLSA  V +R+ ++Q
Sbjct:   50 CYGDKDKRRHCFATWKNISGSIEIVKQGCW------------LDDINCYDRTDCVEKKDSPEVYFCCCEGNMCNEKFSYFPEMEVTQPTSNPVT------PKPPYYNILLYSLVPLMLIAGIVICAFWVYRHHKMAYP---PVLV---PTQDPGPPPPSPLLGLKPLQLLEVKARGRFGCVWKAQLLNEYVAVKIFPIQDKQSWQNEYEVYSLPGMKHENILQFIGAEKRGTSVD-VDLWLITAFHEKGSLSDFLKANVVSWNELCHIAETMARGLAYLHEDIPGLKDGHKPAISHRDIKSKNVLLKNNLTACIADFGLALKFEAGKSAGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELASRCTAADGPVDE-YMLPFEEEIGQHPSLEDMQEVVVHKKKRPVLRDYWQKHAGMAMLCETIEECWDHDAEARLSAGCVGERITQMQ 483
The following BLAST results are available for this feature:
BLAST of TCONS_00050449-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
AVR2A4.391e-9536.96Activin receptor type-2A OS=Homo sapiens GN=ACVR2A... [more]
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