TCONS_00045941-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00045941-protein
Unique NameTCONS_00045941-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length1185

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00045941-protein ID=TCONS_00045941-protein|Name=TCONS_00045941-protein|organism=Clytia hemisphaerica|type=polypeptide|length=1185bp
MESEYLADPREDVVNSNTVDDNSNGLPQNGEKEQKNAIDEEKKEELDEKI
RKTSDSIYSLKHTPVLSIAHILQQKYIYLNGCLDKEQHPILICSFNRSLG
SLDQDDFKSTVNYFKEISSVLWERCKFLVIIDRQHGKWNSVKSILSNLQV
FDADEIFKILLLKPQGFLQRHFGNSDVKQIKELSKHELVFLDNPTMLEDY
VELACLPDEFGGFDSFNVNEWVEYTTAVERFQQTCIKIRNRVKEFRTLFG
SRVPLCSVTEIEQQAKQQRQMVTDIQEDIKCASEIAETLAPIVDKPLSHS
RKGPSALERYNSAQLKAYTECLSKYHDEIEALWQKQANFHEQSKELCGFE
ESFGQISIKLMQITSILDGRTDIGDSLSSANELMYELDDFELKRKEPYNE
MMKLKEKGMQMVAFFGEFAKESVVVRCNEIKHLLKDFEIKLEARKQLLQV
SLDVFTCLDQIEKWCQVGVELLASQPVEAFNQEEAAKKCYEDIQNFMKNK
SGISMNRIRKLKELCQKLGNPSIDERCENSFKRIQEVTEMLEKREASLKK
VALKPKRPVQRVEAIVINKDYDLQKEKGSQSPKIPQTPIITTPTGGVTKE
SIEVVVTDDIEKYKRNKTFRKSLRLSFKRPVSSPAQLQLAEYEEDPEHRK
KIRFIVAELCETEIIYVKDLKEIIEGYFAMFDNPSFNVPEQFRSQKAVIF
GNIDEIYIFHSEIFLEDLKACKDAPYMAGHCFLDKKEEFQFYATYCKNKP
KSELLRNELHKTTFLQAIQKQLGHPLNLDSYLLKPVQRITKYKLLLTEML
KYVSKKNPAYSDILEALVCMKRVLRNVNDVMHSSGLTGFPKNLDEQGKLL
LQDSFTVWEGKKSTTLKQLTKLGAKHRQVFLFEKCLIFSKKEVENGRDLG
TYQYKGHIWTADIGVTESVRGDANRFEVWSKIVVYTLQANNTDMKTNWLS
EIRKILMSQFEGAKETLTQKLSSDIYKSDDVKQQLRQKLKFLDPSLRAST
PVLNLNPSDIGDRPRMNTFGECSPKKEKLRACTSESNLLDDNRSRSTDSL
WSDSEFEDDAENAVIEETTNLPDDDANKTTSEEIFEEEVSPRTQGEIQFC
SVADYEAMEETELSLKYGDKVSLIKEGDDGWWYCKSLETNQEGWAPSGYL
EINALDVTDGRSKSPPIEPVKPSKPSPKKRLETAV
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_029362XLOC_029362Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00045941TCONS_00045941Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001849PH_domain
IPR000219DH-domain
IPR001452SH3_domain
IPR001251CRAL-TRIO_dom
IPR011993PH_dom-like
Vocabulary: Biological Process
TermDefinition
GO:0035023regulation of Rho protein signal transduction
Vocabulary: Molecular Function
TermDefinition
GO:0005089Rho guanyl-nucleotide exchange factor activity
GO:0005515protein binding
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0035023 regulation of Rho protein signal transduction
molecular_function GO:0005515 protein binding
molecular_function GO:0005089 Rho guanyl-nucleotide exchange factor activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
NoneNo IPR availableCOILSCoilCoilcoord: 258..278
NoneNo IPR availableCOILSCoilCoilcoord: 29..49
NoneNo IPR availableGENE3D1.20.58.60coord: 229..344
e-value: 0.22
score: 11.1
NoneNo IPR availableGENE3D2.30.30.40coord: 1087..1122
e-value: 2.0E-8
score: 33.1
NoneNo IPR availableGENE3D2.30.30.40coord: 1123..1183
e-value: 5.7E-11
score: 41.4
NoneNo IPR availableGENE3D1.20.900.10coord: 643..833
e-value: 9.1E-52
score: 175.0
NoneNo IPR availableGENE3D1.20.58.60coord: 454..551
e-value: 0.0025
score: 17.5
NoneNo IPR availableGENE3D1.20.58.60coord: 345..453
e-value: 6.9E-4
score: 19.3
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1..46
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1066..1091
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1157..1185
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 1002..1021
NoneNo IPR availableCDDcd00160RhoGEFcoord: 653..828
e-value: 1.6777E-41
score: 150.911
NoneNo IPR availableCDDcd11856SH3_p47phox_likecoord: 1098..1151
e-value: 1.76408E-16
score: 74.9803
NoneNo IPR availableCDDcd00176SPECcoord: 370..548
e-value: 1.87664E-9
score: 56.6852
NoneNo IPR availableSUPERFAMILY46966Spectrin repeatcoord: 310..449
NoneNo IPR availableSUPERFAMILY46966Spectrin repeatcoord: 403..548
IPR001849Pleckstrin homology domainSMARTSM00233PH_updatecoord: 849..959
e-value: 2.0E-7
score: 40.6
IPR001849Pleckstrin homology domainPROSITEPS50003PH_DOMAINcoord: 842..957
score: 8.171
IPR000219Dbl homology (DH) domainSMARTSM00325RhoGEF_3coord: 655..829
e-value: 3.6E-41
score: 152.7
IPR000219Dbl homology (DH) domainPFAMPF00621RhoGEFcoord: 655..828
e-value: 5.4E-39
score: 134.2
IPR000219Dbl homology (DH) domainPROSITEPS50010DH_2coord: 651..830
score: 32.224
IPR000219Dbl homology (DH) domainSUPERFAMILY48065DBL homology domain (DH-domain)coord: 645..832
IPR001452SH3 domainSMARTSM00326SH3_2coord: 1097..1154
e-value: 4.9E-12
score: 56.0
IPR001452SH3 domainPFAMPF00018SH3_1coord: 1104..1147
e-value: 2.4E-12
score: 46.2
IPR001452SH3 domainPROSITEPS50002SH3coord: 1094..1155
score: 14.563
IPR001452SH3 domainSUPERFAMILY50044SH3-domaincoord: 1098..1177
IPR001251CRAL-TRIO lipid binding domainGENE3D3.40.525.10coord: 61..228
e-value: 4.5E-6
score: 25.9
IPR001251CRAL-TRIO lipid binding domainSUPERFAMILY52087CRAL/TRIO domaincoord: 69..218
IPR011993PH domain-likeGENE3D2.30.29.30coord: 840..963
e-value: 1.5E-24
score: 85.9
IPR011993PH domain-likeSUPERFAMILY50729PH domain-likecoord: 841..960

Blast
[Close]
BLAST of TCONS_00045941-protein vs. Swiss-Prot (Human)
Match: MCF2L (Guanine nucleotide exchange factor DBS OS=Homo sapiens GN=MCF2L PE=1 SV=2)

HSP 1 Score: 449.514 bits (1155), Expect = 1.175e-138
Identity = 341/1173 (29.07%), Postives = 559/1173 (47.66%), Query Frame = 0 
Query:   39 DEEKKEELDEKIRKTSDSIYSLKHTP-------------------VLSIAHILQQKYIYLNGCLDKEQHPILICSFNRSLGSLDQDDFKSTVNYFKEISSVLWERCKFLVIIDRQHGKWNSVK-SILSNLQVFDADEIFKILLLKPQGFLQR-------HFGNSDVKQIKELSKHELVFLDNPTMLEDYVELACLPDEFGGFDSFNVNEWVEYTTAVERFQQTCIKIRNRVKEFRT-LFGSRVP---------LCSVTEIEQQAKQQRQMVTDIQEDIKCASEIAETLAPIVDKPLSHSRKGPSALERY--NSAQLKAYTECLSKYHDEIEALWQKQANFHEQSKELCGFEESFGQISIKLMQITSILDGRTDIGDSLSSANELMYELDDFELKRKEPYNEMMKLKEKGMQMVAFFGEFAKESVVVRCNEIKHLLKDFEIKLEARKQLLQVSLDVFTCLDQIEKWCQVGVELLASQPVEAFNQEEAAKKCYEDIQNFMKNKSGISMNRIRKLKELCQKLGNPSIDERCENSFKRIQEVTEMLEKREASLKKVALKPKRPVQ----RVEAIVINKDYDLQKEKGSQSPKIPQTPIITTPTGGVTKESIEVVVTDDIEKYKRNKTFRKSLRLSFKRPVSSPAQLQLAEYEEDPEHRKKIRFIVAELCETEIIYVKDLKEIIEGYFAMFDNP--SFNVPEQFRSQKAVIFGNIDEIYIFHSEIFLEDLKACKDAPYMAGHCFLDKKEEFQFYATYCKNKPKSELLRNELHKTTFLQAIQKQLGHPLNLDSYLLKPVQRITKYKLLLTEMLKYVSKKNPAYSDILEALVCMKRVLRNVNDVMHSSGLTGFPKNLDEQGKLLLQDSFTVWEGKK--STTLKQLTKLGAKHRQVFLFEKCLIFSKKEVENGRDL---GTYQYKGHIWTADIGVTESVRGDANRFEVW--SKIVVYTLQANNTDMKTNWLSEIRKILMSQFEGAKETLTQKLSSDIYKSDDVKQQLRQKLKFLDPSLRASTPVLNLNPSDIGDRPRMNTFGECSPKKEKLRACTSESNLLDDNRSRSTDSLWSDSEFEDDAENAVIEETTNLPDDDANKTTSEEIF-----EEE--VSPRTQGEIQFCSVADYEAMEETELSLKYGDKVSLIKEGDDGWWYCKSLETNQEGWAPSGYLEI 1152
            +E KKEE D +I   SD I  ++ TP                      I   L++++ YL+G   ++  P++      +   +   +F++ + Y   I S+      F+++IDR+  KW SVK S+L     F A+ +  +L+L+P GF QR        F   D K      K  ++ L +   L  Y++ + L ++ GG   +  + W+   TA+E F     +    ++ F T L  + +P         LC+ TE + +AK+      D++  +K    + E+L     + L      PS  +    N A ++     L++     +  W K     EQ  +L  FE+ F ++   L   +  +   TDIG+SL+    L+ +L  FE K          L   G Q++     +A +S+  +C E++HL   F  ++  R+ LL  SL++   L+   KWC  G+ LLASQPV+    ++ A+   ++I+ F++  +   +  +  + +  + + N  + E     F++   + E+  +R+ASLKK+A +  RPVQ    R EA+          +    SP I +    ++  GG  +             Y+R K+            +S   Q + +  EE+       R +++EL +TE  YV++L  ++EGY A  DNP  +  +     ++K V+FGN++EIY FH+ IFL +L+   D P + G CFL++ E+FQ Y  YC+NKP+SE L  +     F Q  Q++L H L+LDSYLLKPVQRITKY+LLL EMLKY S+      D+ EAL  +  +L+ VND MH   +TG+  NL + GKLL+Q SF+VW   K   T +K+L +     R +FL EK ++F KK  ENG       +Y YK  +  A +G+TE+V+GDA +FE+W  ++  VY +QA   ++K  W++EIRK+L SQ +  +E    +              L Q      P+  +++P         G+   +    E       L    S + L    +       WS +    +A           P+DD   +++EE       EE+  + P+     ++  VAD+E      L ++ GD V L++EGD+G WY +   T +EGW P+  L +
Sbjct:   25 NEAKKEETDHQI-DVSDVIRLVQDTPEATAMATDEIMHQDIVPLCAADIQDQLKKRFAYLSGGRGQDGSPVITFPDYPAFSEIPDKEFQNVMTYLTSIPSLQDAGIGFILVIDRRRDKWTSVKASVLRIAASFPAN-LQLVLVLRPTGFFQRTLSDIAFKFNRDDFKM-----KVPVIMLSSVPDLHGYIDKSQLTEDLGGTLDYCHSRWLCQRTAIESFALMVKQTAQMLQSFGTELAETELPNDVQSTSSVLCAHTEKKDKAKE------DLRLALKEGHSVLESL-----RELQAEGSEPSVNQDQLDNQATVQRLLAQLNETEAAFDEFWAKHQQKLEQCLQLRHFEQGFREVKAILDAASQKIATFTDIGNSLAHVEHLLRDLASFEEKSGVAVERARALSLDGEQLIGN-KHYAVDSIRPKCQELRHLCDQFSAEIARRRGLLSKSLELHRRLETSMKWCDEGIYLLASQPVDKCQSQDGAEAALQEIEKFLETGAENKIQELNAIYKEYESILNQDLMEHVRKVFQKQASMEEVFHRRQASLKKLAARQTRPVQPVAPRPEALA---------KSPCPSPGIRRGSENSSSEGGALRRG----------PYRRAKS-----------EMSESRQGRGSAGEEEESLAILRRHVMSELLDTERAYVEELLCVLEGYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIYHFHNRIFLRELENYTDCPELVGRCFLERMEDFQIYEKYCQNKPRSESLWRQCSDCPFFQECQRKLDHKLSLDSYLLKPVQRITKYQLLLKEMLKY-SRNCEGAEDLQEALSSILGILKAVNDSMHLIAITGYDGNLGDLGKLLMQGSFSVWTDHKRGHTKVKELARFKPMQRHLFLHEKAVLFCKKREENGEGYEKAPSYSYKQSLNMAAVGITENVKGDAKKFEIWYNAREEVYIVQAPTPEIKAAWVNEIRKVLTSQLQACREASQHR-------------ALEQSQSLPLPAPTSTSP-------SRGNSRNIKKLEERKTDPLSLEGYVSSAPL---TKPPEKGKGWSKTSHSLEA-----------PEDDGGWSSAEEQINSSDAEEDGGLGPKKLVPGKYTVVADHEKGGPDALRVRSGDVVELVQEGDEGLWYVRDPTTGKEGWVPASSLSV 1113
The following BLAST results are available for this feature:
BLAST of TCONS_00045941-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
MCF2L1.175e-13829.07Guanine nucleotide exchange factor DBS OS=Homo sap... [more]
back to top