TCONS_00036674-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00036674-protein
Unique NameTCONS_00036674-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length886

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00036674-protein ID=TCONS_00036674-protein|Name=TCONS_00036674-protein|organism=Clytia hemisphaerica|type=polypeptide|length=886bp
MILKKKKISLVFICLFIANQCTQQGKTSQGGKKKRTGLQIRKRSNNSSDY
VLTCINAPKQRESAKRKTIREKRISIQWYKDTKEWGIERYFKATGRLYKH
NDNQRKLILIGIREADSGTYHCVPFDHPSLVNSVDIPPKAAPQIHSYLPR
IRIKKINEFTKFSCVTSSKYARSWGWFINGKKVDQDDRQNFKVVKFNYLR
IQKISYEYDRLNKVECVVTNDFGTSTMNYTLIVEGQQTKLKFVKIRERPF
FDLGLEGHTMDCRAFGKRPLNITWYHDGVDIRRKYRTGYQYFFLDDDHQR
LTINNAHYTDCGIYKCVLKNKYGSISRQSTFRWPGPHITFNHLDGRAPGI
KLISAAIGEELVMETTFSDFDLTTNFRLELFKLVSTTHQKASELAWNASS
IIDLEDNHLPSDVHGTPNFVDDQGVVMENMNRFVKYMVGSINNRGTSKKV
KMVMKNITKHSFGDYMLMVSTQYSYDVFNFTIVQDSPAGEDDSTVEIAVG
VTIPILIVVVIVSYVYFKSPHRYLKPRRRSDIMPIVRQDSDASFEAIAVR
RIRQSFYDEHIDSHWEIDPSKLTKYESIGAGNFGDVFRGQLEDLNGNLTT
VAIKTVKGSASDGDINNFFKEIEIMKRVDGRDHPNVLAFYGVCTRNLFAV
LEYCSNGNLRDYLRSKRPSEENKDIGLDRTEMLTIYSQICDGLCFLASKN
IIHRDIAARNVLVTSDLTMKIADFGLARSLNKDYYQMRSTGEMPILWMAI
ESITKGVFTVKSDVWSFAVLMWEVETLGGRPYTGISVQLLSSFLTSGRRL
HKPHWTPEKIYTIMLMCWEEEPSRRPSFEDLQMIFDSIANTTSTTSSSSY
TALVHRQFHSDILEVVPNHLAVEGLRQSKSNHYNTL
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_021652XLOC_021652Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00036674TCONS_00036674Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR001245Ser-Thr/Tyr_kinase_cat_dom
IPR003598Ig_sub2
IPR020635Tyr_kinase_cat_dom
IPR003599Ig_sub
IPR013098Ig_I-set
IPR013783Ig-like_fold
IPR008266Tyr_kinase_AS
IPR017441Protein_kinase_ATP_BS
IPR007110Ig-like_dom
IPR000719Prot_kinase_dom
IPR011009Kinase-like_dom
Vocabulary: Molecular Function
TermDefinition
GO:0004672protein kinase activity
GO:0004713protein tyrosine kinase activity
GO:0005524ATP binding
Vocabulary: Biological Process
TermDefinition
GO:0006468protein phosphorylation
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006468 protein phosphorylation
molecular_function GO:0005524 ATP binding
molecular_function GO:0004672 protein kinase activity
molecular_function GO:0004713 protein tyrosine kinase activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPRINTSPR00109TYRKINASEcoord: 651..664
score: 47.35
coord: 695..713
score: 58.98
coord: 806..828
score: 42.21
coord: 743..753
score: 48.98
coord: 762..784
score: 59.67
IPR001245Serine-threonine/tyrosine-protein kinase, catalytic domainPFAMPF07714Pkinase_Tyrcoord: 573..833
e-value: 5.2E-83
score: 278.2
IPR003598Immunoglobulin subtype 2SMARTSM00408igc2_5coord: 255..323
e-value: 1.3E-4
score: 31.3
IPR020635Tyrosine-protein kinase, catalytic domainSMARTSM00219tyrkin_6coord: 572..835
e-value: 4.2E-110
score: 381.8
IPR003599Immunoglobulin subtypeSMARTSM00409IG_3ccoord: 39..137
e-value: 78.0
score: 3.7
coord: 149..234
e-value: 66.0
score: 4.3
coord: 249..334
e-value: 1.8
score: 17.6
NoneNo IPR availableGENE3D3.30.200.20coord: 552..653
e-value: 2.9E-21
score: 74.9
NoneNo IPR availableGENE3D1.10.510.10coord: 654..881
e-value: 7.2E-47
score: 159.2
NoneNo IPR availablePIRSFPIRSF000615TyrPK_CSF1-Rcoord: 667..882
e-value: 1.2E-58
score: 197.0
coord: 80..334
e-value: 0.22
score: 7.5
coord: 439..672
e-value: 1.2E-10
score: 38.1
NoneNo IPR availableCDDcd00096Igcoord: 74..123
e-value: 0.00140341
score: 36.6983
NoneNo IPR availableCDDcd00096Igcoord: 259..327
e-value: 1.43567E-8
score: 52.1063
NoneNo IPR availableCDDcd00192PTKccoord: 578..836
e-value: 3.71115E-115
score: 353.767
IPR013098Immunoglobulin I-setPFAMPF07679I-setcoord: 258..327
e-value: 1.3E-9
score: 37.9
IPR013783Immunoglobulin-like foldGENE3D2.60.40.10coord: 41..127
e-value: 2.4E-5
score: 23.5
IPR013783Immunoglobulin-like foldGENE3D2.60.40.10coord: 256..332
e-value: 4.1E-12
score: 45.8
IPR013783Immunoglobulin-like foldGENE3D2.60.40.10coord: 133..243
e-value: 3.6E-6
score: 26.3
IPR008266Tyrosine-protein kinase, active sitePROSITEPS00109PROTEIN_KINASE_TYRcoord: 701..713
IPR017441Protein kinase, ATP binding sitePROSITEPS00107PROTEIN_KINASE_ATPcoord: 578..604
IPR007110Immunoglobulin-like domainPROSITEPS50835IG_LIKEcoord: 142..234
score: 6.578
IPR007110Immunoglobulin-like domainPROSITEPS50835IG_LIKEcoord: 52..122
score: 7.395
IPR007110Immunoglobulin-like domainPROSITEPS50835IG_LIKEcoord: 256..332
score: 9.882
IPR007110Immunoglobulin-like domainSUPERFAMILY48726Immunoglobulincoord: 258..331
IPR007110Immunoglobulin-like domainSUPERFAMILY48726Immunoglobulincoord: 115..122
coord: 73..85
coord: 164..234
IPR000719Protein kinase domainPROSITEPS50011PROTEIN_KINASE_DOMcoord: 572..835
score: 37.517
IPR011009Protein kinase-like domainSUPERFAMILY56112Protein kinase-like (PK-like)coord: 557..836

Blast
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BLAST of TCONS_00036674-protein vs. Swiss-Prot (Human)
Match: FGFR3 (Fibroblast growth factor receptor 3 OS=Homo sapiens GN=FGFR3 PE=1 SV=1)

HSP 1 Score: 240.736 bits (613), Expect = 1.295e-67
Identity = 187/635 (29.45%), Postives = 294/635 (46.30%), Query Frame = 0 
Query:  262 CRAFGKRPLNITWYHDGVDIRRKYRTGYQYFFLDDDHQRLTINNAHYTDCGIYKCVLKNKYGSISRQSTFRWPGPHITFNHLDGRAPGIKLISAAIGEELVMETTFSDFDLTTNFRLELFKLVSTTHQKASELAWNASSIIDLEDNHLPSDVHGTPNFVDDQGVVMENMNRFVKYMVGSINNRGTSKKVKMVMKNITKHSFGDYMLMVSTQYSYDVFNFTIVQDSPAGEDDSTVEIAVGVTIPIL----------IVVVIVSYVYFKSP----------HRYLK-PRRR----------SDIMPIVRQDSDASFEAIAVRRIRQSFYDEHIDSHWEIDPSKLTKYESIGAGNFGDVFRGQL----EDLNGNLTTVAIKTVKGSASDGDINNFFKEIEIMKRVDGRDHPNVLAFYGVCTRN--LFAVLEYCSNGNLRDYLRSKRPSEENKDIGLDRT--------------EMLTIYSQICDGLCFLASKNIIHRDIAARNVLVTSDLTMKIADFGLARSL-NKDYYQMRSTGEMPILWMAIESITKGVFTVKSDVWSFAVLMWEVETLGGRPYTGISVQLLSSFLTSGRRLHKPHWTPEKIYTIMLMCWEEEPSRRPSFEDLQMIFDSIANTTST 844
            C A G    +I+W  +G + R ++R G     L      L + +   +D G Y CV++NK+GSI RQ+         T + L+ R+P   ++ A +      +T     D+   F  +++       Q    +  N S +             GTP               +V  +  +  N    +   + + N+T    G+Y  +      +   +  +V   PA E+    + A  V   IL          +VV  V+    +SP          H+  + P +R          S   P+VR    +S E   +  + +   +   D  WE+  ++LT  + +G G FG V   +     +D      TVA+K +K  A+D D+++   E+E+MK +    H N++   G CT+   L+ ++EY + GNLR++LR++RP       GLD +              ++++   Q+  G+ +LAS+  IHRD+AARNVLVT D  MKIADFGLAR + N DYY+  + G +P+ WMA E++   V+T +SDVWSF VL+WE+ TLGG PY GI V+ L   L  G R+ KP      +Y IM  CW   PS+RP+F+ L    D +   TST
Sbjct:  176 CPAAGNPTPSISWLKNGREFRGEHRIGG--IKLRHQQWSLVMESVVPSDRGNYTCVVENKFGSI-RQT--------YTLDVLE-RSPHRPILQAGLPAN---QTAVLGSDV--EFHCKVYSDAQPHIQWLKHVEVNGSKV----------GPDGTP---------------YVTVLKTAGANTTDKELEVLSLHNVTFEDAGEYTCLAGNSIGFSHHSAWLVV-LPAEEELVEADEAGSVYAGILSYGVGFFLFILVVAAVTLCRLRSPPKKGLGSPTVHKISRFPLKRQVSLESNASMSSNTPLVRIARLSSGEGPTLANVSE--LELPADPKWELSRARLTLGKPLGEGCFGQVVMAEAIGIDKDRAAKPVTVAVKMLKDDATDKDLSDLVSEMEMMKMIG--KHKNIINLLGACTQGGPLYVLVEYAAKGNLREFLRARRPP------GLDYSFDTCKPPEEQLTFKDLVSCAYQVARGMEYLASQKCIHRDLAARNVLVTEDNVMKIADFGLARDVHNLDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDVWSFGVLLWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKPANCTHDLYMIMRECWHAAPSQRPTFKQLVEDLDRVLTVTST 757
The following BLAST results are available for this feature:
BLAST of TCONS_00036674-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
FGFR31.295e-6729.45Fibroblast growth factor receptor 3 OS=Homo sapien... [more]
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