TCONS_00035360-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00035360-protein
Unique Name	TCONS_00035360-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	699

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00035360-protein ID=TCONS_00035360-protein|Name=TCONS_00035360-protein|organism=Clytia hemisphaerica|type=polypeptide|length=699bp
MKLLTWNVNGIRAASIKSKSIKLLLDSLDADIICLQETKITRNLLTTDIG
NIDEYLAFFSFSKKRGGYSGVVTYCKKSCCPVAAEEGITGVLCSTEKTQS
IGYYPASFHDEFTTQELKDLDSEGRVIITEHKLKDGRHLCIVNVYCPMAV
VDNKERYEFKMKFYHLLEMRCRHLEKAGKHVMVVGDLNVSHQRIDHCDPE
QDFEASRSRKWFNSIIIRNTRILKTHQHESLSEFNSKDESYHDLSEGRKT
SSSSNNRIFVKTQEVSATVENDLNDADSKTDFPCTHAINNIDISEAKNSK
LMESSEFRAIKSLRIRNSDITDDDGGRQFGDHDDVLELKTQIKKKELSNS
KYNDTKNSNDEEQSSNKLQSMNGLKSSSLAKTVSIDFCESFSPPSNEDTP
HSQYDNSDCDDGKQQFCDDFHFVEDSLKTPFLVDVFRAMHPTRREAFTCW
NTKERARETNYGTRIDYVLTTRDFYESDAIEWCDIRPDIYGSDHCPVECS
LKCSFSTSSIIPSTCVIFMPELSGKQQNIKTYFANSVTASNGKRLSGDIC
QNFDNSSNKRLKLCRLNDKKVSKTKKDNLLAYFDSSGKGKCLENTTGLIS
KSNADVKSFETIDKNFDNITKLKRLQSLSNDKSKTTKWKGIFKGPEPVPK
CSGHNEPCILQTVKKEGPNIGRQFYCCKRPSGHATNKEARCKFFKWKNK

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_020652	XLOC_020652	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00035360	TCONS_00035360	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR005135	Endo/exonuclease/phosphatase
IPR010666	Znf_GRF
IPR020847	AP_endonuclease_F1_BS
IPR004808	AP_endonuc_1

Vocabulary: **Molecular Function**
Term	Definition
GO:0008270	zinc ion binding
GO:0003677	DNA binding
GO:0004519	endonuclease activity
GO:0004518	nuclease activity

Vocabulary: **Biological Process**
Term	Definition
GO:0006281	DNA repair

Vocabulary: **Cellular Component**
Term	Definition
GO:0005622	intracellular

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
biological_process	GO:0006281	DNA repair
cellular_component	GO:0005622	intracellular
molecular_function	GO:0003677	DNA binding
molecular_function	GO:0004519	endonuclease activity
molecular_function	GO:0004518	nuclease activity
molecular_function	GO:0008270	zinc ion binding

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR005135	Endonuclease/exonuclease/phosphatase	PFAM	PF03372	Exo_endo_phos	coord: 4..494 e-value: 2.4E-13 score: 50.1
IPR005135	Endonuclease/exonuclease/phosphatase	GENE3D	3.60.10.10		coord: 1..510 e-value: 1.2E-41 score: 142.3
IPR005135	Endonuclease/exonuclease/phosphatase	SUPERFAMILY	56219	DNase I-like	coord: 431..502 coord: 1..90 coord: 120..218
IPR010666	Zinc finger, GRF-type	PFAM	PF06839	zf-GRF	coord: 650..698 e-value: 2.5E-10 score: 40.2
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 347..372
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 234..257
IPR020847	AP endonuclease 1, binding site	PROSITE	PS00726	AP_NUCLEASE_F1_1	coord: 30..39
IPR004808	AP endonuclease 1	PROSITE	PS51435	AP_NUCLEASE_F1_4	coord: 1..503 score: 36.673

Blast

[Close]

BLAST of TCONS_00035360-protein vs. Swiss-Prot (Human)
Match: APEX2 (DNA-(apurinic or apyrimidinic site) lyase 2 OS=Homo sapiens GN=APEX2 PE=1 SV=1)

HSP 1 Score: 202.986 bits (515), Expect = 2.098e-57
Identity = 100/232 (43.10%), Postives = 152/232 (65.52%), Query Frame = 0

Query:    1 MKLLTWNVNGIR----------AASIKSKSIKLLLDSLDADIICLQETKITRNLLTTDIGNIDEYLAFFSFSKKRGGYSGVVTYCKKSCCPVAAEEGITGVLCSTEKTQSIGYYPASFHDEFTTQELKDLDSEGRVIITEHKLK--DGRH--LCIVNVYCPMAVVDNKERYEFKMKFYHLLEMRCRHLEKAGKHVMVVGDLNVSHQRIDHCDPE--QDFEASRSRKWFNSII 216
            +++++WN+NGIR           ++  + ++  +LD LDADI+CLQETK+TR+ LT  +  ++ Y ++FSFS+ R GYSGV T+CK +  PVAAEEG++G+  +  +   +G Y     DEFT +EL+ LDSEGR ++T+HK++  +G+   L ++NVYCP A     ER  FKM+FY LL++R   L  AG HV+++GDLN +H+ IDH D    + FE    RKW +S++
Sbjct:    2 LRVVSWNINGIRRPLQGVANQEPSNCAAVAVGRILDELDADIVCLQETKVTRDALTEPLAIVEGYNSYFSFSRNRSGYSGVATFCKDNATPVAAEEGLSGLFAT--QNGDVGCY--GNMDEFTQEELRALDSEGRALLTQHKIRTWEGKEKTLTLINVYCPHADPGRPERLVFKMRFYRLLQIRAEALLAAGSHVIILGDLNTAHRPIDHWDAVNLECFEEDPGRKWMDSLL 229

HSP 2 Score: 155.992 bits (393), Expect = 1.089e-40
Identity = 91/286 (31.82%), Postives = 136/286 (47.55%), Query Frame = 0

Query:  430 PFLVDVFRAMHPTRREAFTCWNTKERARETNYGTRIDYVLTTRDFYESDAIEWCDIRPDIYGSDHCPVECSLKCSFSTSSIIPSTCVIFMPELSGKQQNIKTYFA----------NSVTASNGKRLSGDICQNFDNSSNKRLKLCRLNDKKVSKTKKDNLLAYFDSSG---------KGKCLENTTGLISKSNADVKSFETIDKNFDNITKLKRLQSLSNDKSKTTKWKGIFKGPEPVPKCSGHNEPCILQTVKKEGPNIGRQFYCCKRPSGHATNKEARCKFFKW 696
            PF +D +R   P +  AFTCW+    AR  NYG+R+DYVL  R     D  +   + P++ GSDHCPV   L  S   +   P  C  F+PE +G Q  I  +            +++  +N  R+    CQN     + R +  ++   +  K    NL +YF  S          +   L   + L++    + K+   + K     ++ K  + L     +T+ WK +  GP   P C GH EPC+++TVKK GPN+GR+FY C RP G  T+  +RC FF W
Sbjct:  242 PF-IDSYRCFQPKQEGAFTCWSAVTGARHLNYGSRLDYVLGDRTLV-IDTFQASFLLPEVMGSDHCPVGAVLSVSSVPAKQCPPLCTRFLPEFAGTQLKILRFLVPLEQSPVLEQSTLQHNNQTRV--QTCQNKAQVRSTRPQPSQVGSSRGQK----NLKSYFQPSPSCPQASPDIELPSLPLMSALMTPKTPEEKAVAKVVKGQAKTSEAKDEKEL-----RTSFWKSVLAGPLRTPLCGGHREPCVMRTVKKPGPNLGRRFYMCARPRGPPTDPSSRCNFFLW 514

The following BLAST results are available for this feature:

BLAST of TCONS_00035360-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00035360-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
APEX2	2.098e-57	43.10	DNA-(apurinic or apyrimidinic site) lyase 2 OS=Hom...	[more]

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TCONS_00035360-protein (polypeptide) - C. hemisphaerica