TCONS_00035292-protein (polypeptide) - C. hemisphaerica

Overview


Name	TCONS_00035292-protein
Unique Name	TCONS_00035292-protein
Type	polypeptide
Organism	Clytia hemisphaerica (Jellyfish)
Sequence length	931

Sequence

The following sequences are available for this feature:

polypeptide sequence

polypeptide sequence

>TCONS_00035292-protein ID=TCONS_00035292-protein|Name=TCONS_00035292-protein|organism=Clytia hemisphaerica|type=polypeptide|length=931bp
MAPQASDSAVDLPPKGSADSNGVTVVDSHKQKDSKGCCKTFTDTINASLE
NFFGAIGRIVANNPWPVILIALTISGLCMVGIIELQTENRGEKNWVSQTS
DPVKHKEWVDDVFPIPSRTSKLLLEKKDGSDLLTRDGLLKLYEEDQKVRG
MLFNETGYQWHDICYSASASADCIPASILEVWSYNRTIIENLTDKEIKST
INKGGLLSPMTGRLVTVERLIGGPVVRDNGTIVKASVLKVDYRLQKQDIF
DKGKGRDVDKYADKWEEELEKTFEGGQPDYEVYTFSQWSQAKASEDASNG
DLQFFVIGYIMVIVYLSIMLGSFSRIGHKVLLALAGIGVIGISIGISYGL
GSAFQLKYTAVHNVLPFLLLGIGVDDLFVIVQSWDNIGGPKRDHRSVEEK
ISLAMRHAGVSVLVTSVTDVCAFLIGAATILPALRSFSVWCAIGILAIFL
LTITLFTALLTLDAKRQEKERDACCCCLKLSSSYEPPKCSETKYLKGFLK
NYYARALLSTPGKIVVMVAVAGLLAAGLYGLVGLEQDFDYAWFWPSDSRP
RVFIEKDRIAFPGNGVPGNIYIGRINYWRDGHEHLGKVKEALESDKYVSE
GTVNSWFHQYHDWLRLNHPADLEAGCTETCKVKNEERFYKLLDEFLNGDG
KLYKSLIDIPSSDGRIRASKIQYTHRQLVGSDQQVNAMDSITGTIKPGFI
PDGGEEILPFAFTQNYINWSTNKVISQELVRNIALAGVCVLLVTLFLLSN
VIASVLVVACVAFSLIEIAAFMGFWGLTIDTVTTIILVIAIGLTVDYSVH
IAHGFMASRAGGRNERMTEALYEVGPAVFHGGFSTFLAFLLLSASTSYVF
LTFFKVFFLVVIFGMFHGMVFLPVILSLVGPAPYADHAAENCAASPPVET
PKQNGGHSTAEKDHEMRVVIDGNENTGYVKE

Run BLAST on NCBI

Gene-mRNA-Prot

This polypeptide comes from the following gene feature:


Feature Name	Unique Name	Species	Type
XLOC_020603	XLOC_020603	Clytia hemisphaerica	gene

This polypeptide derives from the following transcript feature(s):


Feature Name	Unique Name	Species	Type
TCONS_00035292	TCONS_00035292	Clytia hemisphaerica	transcript

Annotated Terms

The following terms have been associated with this polypeptide:

Vocabulary: **INTERPRO**
Term	Definition
IPR003392	Ptc/Disp
IPR000731	SSD

Vocabulary: **Cellular Component**
Term	Definition
GO:0016021	integral component of membrane

GO Annotation

GO Assignments

This polypeptide is annotated with the following GO terms.

Category	Term Accession	Term Name
cellular_component	GO:0016021	integral component of membrane

InterPro

Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01


IPR Term	IPR Description	Source	Source Term	Source Description	Alignment
IPR003392	Protein patched/dispatched	PFAM	PF02460	Patched	coord: 217..879 e-value: 1.5E-92 score: 311.0
None	No IPR available	GENE3D	1.20.1640.10		coord: 246..474 e-value: 3.4E-41 score: 140.3
None	No IPR available	GENE3D	1.20.1640.10		coord: 665..882 e-value: 8.7E-34 score: 116.1
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 1..26
None	No IPR available	MOBIDB_LITE	mobidb-lite	disorder_prediction	coord: 894..931
None	No IPR available	SUPERFAMILY	82866	Multidrug efflux transporter AcrB transmembrane domain	coord: 255..462
None	No IPR available	SUPERFAMILY	82866	Multidrug efflux transporter AcrB transmembrane domain	coord: 713..880
IPR000731	Sterol-sensing domain	PROSITE	PS50156	SSD	coord: 752..878 score: 12.188
IPR000731	Sterol-sensing domain	PROSITE	PS50156	SSD	coord: 301..462 score: 34.952

Blast

[Close]

BLAST of TCONS_00035292-protein vs. Swiss-Prot (Human)
Match: NPC1 (Niemann-Pick C1 protein OS=Homo sapiens GN=NPC1 PE=1 SV=2)

HSP 1 Score: 222.631 bits (566), Expect = 8.025e-60
Identity = 232/997 (23.27%), Postives = 426/997 (42.73%), Query Frame = 0

Query:   19 DSNGVTVVDSHKQKDSKGCCKTFTDTINASLENFFGAIGRIVANNPWPVILIALTISGLCMVGIIELQTENRGEKNWVSQTSDPVKHKEWVDDVFPIPSRTSKLLLEKK-----------DGSD--------LLTRDGLLKLYEEDQKVRGMLFNETGYQWHDICYS--ASASADCIPASILEVWSYNRTIIEN----------------LTDKEIKSTINKGGLL-SPMTGRLVTVERLIGGPVV-------RDNGTIVKASVLKVDYRLQKQDIFDKGKGRDVDKY--ADKWEEELEKTFEG-GQPDYEVYTFSQWSQAKASEDASNGDLQFFVIGYIMVIVYLSIMLGSFSR-----IGHKVLLALAGIGVIGISIGISYGLGSAFQLKYT-AVHNVLPFLLLGIGVDDLFVIVQSWDNIGGPKRDHR----SVEEKISLAMRHAGVSVLVTSVTDVCAFLIGAATILPALRSFSVWCAIGILAIFLLTITLFTALLTLDAKRQEKERDACCCCLKLSSSYEPPKCSETKYLKGFLKNYYARALLSTPGKIVVMVAVAGLLAAGLYGLVGLEQDFDYAWFWPSDSRPRVFIEKDRIAFPGNGVPGNIYIGRINYW--RDGHEH--------------------LGKVKEALESDKYVSEGTV-NSWFHQYHDWL-------RLNHPAD-------LEAGCTETCKVKNEER-------FYKLLDEFLN---------GDGKLYKSLIDIPSSDG-RIRASKIQYTHRQLVGSDQQVNAM-------DSITGTIKPGFIPDGGEEILPFAFTQNYINWSTNKVISQELVRNIALAGVCVLLVTLFLL-SNVIASVLVVACVAFSLIEIAAFMGFWGLTIDTVTTIILVIAIGLTVDYSVHIAHGFMASRAGGRNERMTEALYEVGPAVFHG-GFSTFLAFLLLSASTSYVFLTF-FKVFFLVVIFGMFHGMVFLPVILSLVGPAPYADHAAENCA 893
            DSN    V++   K    CC   +      L   F   G     NP  VI  +L     C  G++ ++        W + +S     KE+ D  F    RT +L++               G+D        +     +L L    + +     NET     DIC +  +  + +C   S+L  +  + +++++                L      +++N   LL  P  G         GGPV         D+     A+ L + + +            D +K   A  WE+E     +    P+  +   ++ S        S+ D+   VI Y ++ +Y+S+ LG         +  KV L +AGI ++  S+  S G+ S   L  T  V  V+PFL+L +GVD++F++VQ++      +RD R    ++++++   +     S+ ++S ++  AF +GA +++PA+ +FS++  + +   FLL IT F +LL LD KRQEK R    CC++ +      + SE+   + F KN Y+  LL    + +V+    G+L+  +  L  ++   D +   P DS    + +          +   ++ G   Y+   +GH++                    + ++  A + D Y   G   +SW   Y DW+       R+++  D       ++  C     +  E +       F + L  FL+         G    Y S ++I    G R+ A+     H  L  S   ++A+        ++T T+        G     F ++  Y+ +     I  + + N+ ++   + LVT+ LL   + ++V++ A +A  L+ +   M  WG++++ V+ + LV++ G++V++  HI   F  S  G R ER  EAL  +G +VF G   + F   ++L+ + S +F  F F+++  +V+ G  HG++FLPV+LS +GP+    + A++CA
Sbjct:  306 DSNIAFSVNA-SDKGEASCCDPVSAAFEGCLRRLFTRWGSFCVRNPGCVIFFSLVFITACSSGLVFVRVTTNPVDLWSAPSSQARLEKEYFDQHFGPFFRTEQLIIRAPLTDKHIYQPYPSGADVPFGPPLDIQILHQVLDLQIAIENITASYDNET-VTLQDICLAPLSPYNTNCTILSVLNYFQNSHSVLDHKKGDDFFVYADYHTHFLYCVRAPASLNDTSLLHDPCLGTF-------GGPVFPWLVLGGYDDQNYNNATALVITFPVNNY-------YNDTEKLQRAQAWEKEFINFVKNYKNPNLTISFTAERSIEDELNRESDSDVFTVVISYAIMFLYISLALGHMKSCRRLLVDSKVSLGIAGILIVLSSVACSLGVFSYIGLPLTLIVIEVIPFLVLAVGVDNIFILVQAY------QRDERLQGETLDQQLGRVLGEVAPSMFLSSFSETVAFFLGALSVMPAVHTFSLFAGLAVFIDFLLQITCFVSLLGLDIKRQEKNRLDIFCCVRGAEDGTSVQASESCLFR-FFKNSYSPLLLKDWMRPIVIAIFVGVLSFSIAVLNKVDIGLDQSLSMPDDSYMVDYFKS---------ISQYLHAGPPVYFVLEEGHDYTSSKGQNMVCGGMGCNNDSLVQQIFNAAQLDNYTRIGFAPSSWIDDYFDWVKPQSSCCRVDNITDQFCNASVVDPACVRCRPLTPEGKQRPQGGDFMRFLPMFLSDNPNPKCGKGGHAAYSSAVNILLGHGTRVGATYFMTYHTVLQTSADFIDALKKARLIASNVTETMGIN-----GSAYRVFPYSVFYVFYEQYLTIIDDTIFNLGVSLGAIFLVTMVLLGCELWSAVIMCATIAMVLVNMFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSMKGSRVERAEEALAHMGSSVFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSYIGPSV---NKAKSCA 1262

The following BLAST results are available for this feature:

BLAST of TCONS_00035292-protein vs. Swiss-Prot (Human)

BLAST of TCONS_00035292-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1


Match Name	E-value	Identity	Description
NPC1	8.025e-60	23.27	Niemann-Pick C1 protein OS=Homo sapiens GN=NPC1 PE...	[more]

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TCONS_00035292-protein (polypeptide) - C. hemisphaerica