TCONS_00034967-protein (polypeptide) - C. hemisphaerica

Overview
NameTCONS_00034967-protein
Unique NameTCONS_00034967-protein
Typepolypeptide
OrganismClytia hemisphaerica (Jellyfish)
Sequence length487

Sequence
The following sequences are available for this feature:

polypeptide sequence

>TCONS_00034967-protein ID=TCONS_00034967-protein|Name=TCONS_00034967-protein|organism=Clytia hemisphaerica|type=polypeptide|length=487bp
DSLILNFNTRAMALGLGFLYLLILRVCTVKTTLSSHEIQKIREKIFDGYD
ANIMPLEEGRPINVSVDFFINDMVPLHAASMHFSIDCFFTLQWRDYRLQW
DPPNNETYVLPFDDRIAKDLWMPNVYFPELKHGYNHKVPMPNELIYLYPD
GNVVYNQRILMDSFCPMNLTYYPFDMQHCRLTVEPYSYNMKFVVLFWRDG
KAIDTSEKGNLYVIDFKDVDMSLNSKIVDWGIYGNYSRLSIHLDMTRHSQ
LSLLRDFIPCILIVFLSWVGFWINYKSTPARVALGITTVLTIVTLTNSVR
LNSPHSDSFRSIDVYTLGCNIFVFAAIVEYALVGMSSPKLHHNSEVPSQI
NETKMRRKLLRKRRRNKKKSNNNNDSDDECVPLSSIPGFQEEKRESGCTF
PSRRRKKDSTSISLETVKEDSSPKTNGLTHAERKKSSVRQLGPVVIVTDD
IHAVDKYSRSIFPGVFMILNIIFFVFHVLTPDTVLST
Run BLAST on NCBI
Gene-mRNA-Prot
This polypeptide comes from the following gene feature:
Feature NameUnique NameSpeciesType
XLOC_020357XLOC_020357Clytia hemisphaericagene
This polypeptide derives from the following transcript feature(s):
Feature NameUnique NameSpeciesType
TCONS_00034967TCONS_00034967Clytia hemisphaericatranscript
Annotated Terms
The following terms have been associated with this polypeptide:
Vocabulary: INTERPRO
TermDefinition
IPR006028GABAA/Glycine_rcpt
IPR006201Neur_channel
IPR006202Neur_chan_lig-bd
IPR006029Neurotrans-gated_channel_TM
IPR018000Neurotransmitter_ion_chnl_CS
Vocabulary: Cellular Component
TermDefinition
GO:0016021integral component of membrane
Vocabulary: Biological Process
TermDefinition
GO:0006811ion transport
Vocabulary: Molecular Function
TermDefinition
GO:0005216ion channel activity
GO:0005230extracellular ligand-gated ion channel activity
GO Annotation
GO Assignments
This polypeptide is annotated with the following GO terms.
Category Term Accession Term Name
biological_process GO:0006811 ion transport
cellular_component GO:0016021 integral component of membrane
molecular_function GO:0005230 extracellular ligand-gated ion channel activity
molecular_function GO:0005216 ion channel activity
InterPro
Analysis Name: InterPro Annotations of C. hemisphaerica v1.0
Date Performed: 2017-06-01
IPR TermIPR DescriptionSourceSource TermSource DescriptionAlignment
IPR006028Gamma-aminobutyric acid A receptor/Glycine receptor alphaPRINTSPR00253GABAARECEPTRcoord: 457..477
score: 33.46
coord: 278..299
score: 54.63
coord: 312..333
score: 46.98
coord: 252..272
score: 46.94
IPR006201Neurotransmitter-gated ion-channelPRINTSPR00252NRIONCHANNELcoord: 165..179
score: 49.71
coord: 84..100
score: 34.31
coord: 119..130
score: 25.19
NoneNo IPR availableGENE3D1.20.58.390coord: 253..484
e-value: 5.5E-37
score: 126.5
NoneNo IPR availableMOBIDB_LITEmobidb-litedisorder_predictioncoord: 362..435
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainPFAMPF02931Neur_chan_LBDcoord: 40..248
e-value: 1.4E-40
score: 138.9
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainGENE3D2.70.170.10coord: 38..248
e-value: 3.4E-49
score: 166.8
IPR006202Neurotransmitter-gated ion-channel ligand-binding domainSUPERFAMILY63712Nicotinic receptor ligand binding domain-likecoord: 39..248
IPR006029Neurotransmitter-gated ion-channel transmembrane domainPFAMPF02932Neur_chan_membcoord: 258..474
e-value: 1.2E-26
score: 94.1
IPR006029Neurotransmitter-gated ion-channel transmembrane domainSUPERFAMILY90112Neurotransmitter-gated ion-channel transmembrane porecoord: 257..479
IPR018000Neurotransmitter-gated ion-channel, conserved sitePROSITEPS00236NEUROTR_ION_CHANNELcoord: 165..179

Blast
BLAST of TCONS_00034967-protein vs. Swiss-Prot (Human)
Match: GBRB3 (Gamma-aminobutyric acid receptor subunit beta-3 OS=Homo sapiens GN=GABRB3 PE=1 SV=1)

HSP 1 Score: 223.402 bits (568), Expect = 2.450e-67
Identity = 145/475 (30.53%), Postives = 241/475 (50.74%), Query Frame = 0
Query:   21 LLILRVCTVKTTLSSHEIQKIRE---KIFDGYDANIMPLEEGRPINVSVDFFINDMVPLHAASMHFSIDCFFTLQWRDYRLQWDP-PNNETYVLPFDDRIAKDLWMPNVYFPELKHGYNHKVPMPNELIYLYPDGNVVYNQRILMDSFCPMNLTYYPFDMQHCRLTVEPYSYNMKFVVLFWRDG-KAIDTSEKGNLYVIDFKDVDMSLNSKIVDWGIYGNYSRLSIHLDMTRHSQLSLLRDFIPCILIVFLSWVGFWINYKSTPARVALGITTVLTIVTLTNSVRLNSPHSDSFRSIDVYTLGCNIFVFAAIVEYALVGM----SSPKLHHNSEVPSQINETKMRRKLLRKRRRNKKKSNNNNDSDDECVPLSSIPGFQEEKRESGCTFPSRRRKKDSTSISLETVKEDSSPKTNGLTHAER----KKSSVR----QLGPVVIVTDDIHAVDKYSRSIFPGVFMILNIIFFVFHV 478
            +L+  VC  ++      +  ++E   K+  GYD  + P   G P+ V ++  I  +  +   +M +++  +F   WRD RL +   P N    L  D+R+A  LW+P+ YF   K  + H V + N +I L+PDG V+Y  RI   + C M+L  YP D Q+C L +E Y Y    +  +WR G KA+   E+  + +  F  V+  L S+ V +   G Y RLS+   + R+    +L+ ++P ILI  LSWV FWINY ++ ARVALGITTVLT+ T+   +R   P     ++ID+Y +GC +FVF A++EYA V        P+            + K+  K  + +    K  +N  D+    + L+S+    E    SG    +R       +  ++  K+    + +G    +R    KK+ +R    QL   +    D++A+D++SR +FP  F + N+++++++V
Sbjct:   17 VLVAVVCCAQSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLN----LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVER--IELPQFSIVEHRLVSRNVVFAT-GAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQ-----------RQKKLAEKTAKAKNDRSKSESNRVDAHGNIL-LTSLEVHNEMNEVSGGIGDTRNSAISFDNSGIQYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYV 472          
The following BLAST results are available for this feature:
BLAST of TCONS_00034967-protein vs. Swiss-Prot (Human)
Analysis Date: 2018-01-31 (Blastp Clytia hemisphaerica v1.0 proteins vs SwissProt (Homo sapiens))
Total hits: 1
Match NameE-valueIdentityDescription
GBRB32.450e-6730.53Gamma-aminobutyric acid receptor subunit beta-3 OS... [more]
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